2-Chloroethoxybenzene
Linshang Chemical
HS Code |
201882 |
Chemical Formula | C8H9ClO |
Molecular Weight | 156.61 |
Appearance | Colorless to light yellow liquid |
Boiling Point | 217 - 218 °C |
Density | 1.126 g/cm³ at 25 °C |
Flash Point | 93 °C |
Solubility In Water | Insoluble |
Vapor Pressure | Low |
Odor | Characteristic aromatic odor |
As an accredited 2-Chloroethoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 250g of 2 - chloroethoxybenzene packaged in a sealed glass bottle. |
Storage | 2 - Chloroethoxybenzene should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames as it is potentially flammable. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and incompatible substances to prevent chemical reactions. Ensure proper labeling for easy identification and safety. |
Shipping | 2 - Chloroethoxybenzene should be shipped in tightly - sealed, corrosion - resistant containers. It must be labeled clearly as a chemical, and transported following all relevant regulations for hazardous substances to ensure safety during transit. |
Competitive 2-Chloroethoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
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Tel: +8615365006308
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As a leading 2-Chloroethoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of pharmaceutical synthesis, its role is significant. In the construction of many drug molecules, the introduction of 2-% cyanoethoxy phenyl can optimize the physicochemical properties of drugs, such as improving the lipid solubility of drugs, making it easier to penetrate biofilms, and enhancing the affinity and specificity of drugs to specific targets. For example, in the development of some anti-cancer drugs, by ingeniously connecting this group, the absorption, distribution, metabolism and excretion process of drugs in the body can be improved, thereby improving the efficacy of drugs and reducing toxic side effects.
In the field of materials science, 2-% cyanoethoxy phenyl also plays a key role. In the preparation of polymer materials, it is introduced into the polymer chain as a functional monomer, which can endow the material with unique properties. Like some polymer materials with photoelectric activity, with the special electronic structure of 2-% cyanoethoxy phenyl, it can exhibit excellent fluorescence properties or charge transport ability, and has great application potential in the field of organic Light Emitting Diode (OLED), solar cells and other optoelectronic devices.
In addition, in fine chemical products, this group is also often used. For example, in the synthesis of some high-performance coatings and adhesives, the presence of 2-% cyanoethoxy phenyl can enhance the adhesion, corrosion resistance and other properties of the product, improve product quality and service life. In conclusion, 2-% cyanoethoxy phenyl, with its unique chemical structure, plays an indispensable role in many fields such as medicine, materials, and fine chemicals, promoting the continuous development and progress of related industries.
Looking at its appearance, under room temperature and pressure, it is mostly in the form of a colorless to light yellow liquid. This color and shape are also common in organic compounds. Its texture is uniform, and there are no obvious impurities. It is like a pool of quiet water, which sits quietly in a container.
When it comes to odor, this substance emits a weak and special smell. It is not as fragrant as flowers, nor is it stinky and pungent, but a relatively unique and indescribable smell that needs to be detected by sniffing.
When it comes to solubility, 2-% cyanoethoxy phenyl] propane shows good solubility characteristics in the field of organic solvents. Organic solvents such as common ethanol, ether, acetone, etc. can be fused with it, just like fish entering water, the two are inseparable. However, the solubility in water is extremely limited, just like the incompatibility of oil and water, the two meet, and the boundary is clear.
Then talk about its boiling point, this substance has a specific boiling point value. When the external temperature gradually rises to a certain level, the transition from liquid to gas will occur. The specific value of the boiling point plays a crucial role in industrial production, separation and purification, and is an indispensable parameter for precise control of the production process.
As for the melting point, it is also one of the important physical properties of the substance. In a specific low temperature environment, 2-% cyanoethoxyphenyl] propane will solidify from liquid to solid, and this temperature is the melting point. The characteristics of the melting point help to plan its storage and transportation conditions.
In terms of density, 2-% cyanoethoxyphenyl] propane also has its own fixed value. Density, as the mass of a substance per unit volume, provides key data support for measuring its dosage and occupied space in practical applications.
To sum up, the physical properties of 2-% cyanoethoxyphenyl] propane, from appearance, odor, solubility, boiling point, melting point to density, are unique, and these properties are interrelated. Together, they constitute its unique "identity" in the material world, laying the foundation for its application in many fields.
When it comes to melting, it is like spring ice meeting warmth. At moderate temperatures, it melts slowly, and the transformation is silent, just like the flowers of the night. Its melting point is precise and stable, just like the star track is established, and it is a specific value. This characteristic can be used in many applications to measure accurately and control temperature.
Then again, its solution state is different in various solvents. In polar solvents, such as alcohols, it is like a wanderer returning home, happily blending, and the two are seamless, forming a uniform and clear state, which is like a natural harmony and complements each other. In non-polar solvents, such as oil and water, they are distinct and difficult to miscible. This difference also provides a different path for their separation and purification.
And its chemical properties are also active. In the molecule, specific groups are always ready to participate in the reaction, such as warriors holding swords. When encountering electrophilic reagents, it is like a brave man facing the enemy, and the groups respond enthusiastically, using a unique mechanism to build new structures and derive other substances. This process is like a natural creation, and it is fascinating. It opens up infinite possibilities in the field of organic synthesis, providing cornerstones and opportunities for the creation of new materials and drugs.
First, phthalic anhydride is used as the beginning, and o-carboxybenzamide can be obtained by ammonolysis. This process requires moderate temperature control, and the amount of ammonia and the reaction time are all key. After the meeting of o-carboxybenzamide and ethylene oxide, in the alkaline environment, the two combine to obtain 2-% hydroxyethylaminobenzoic acid. Among them, the type of alkali and the dripping rate of ethylene oxide have a great impact on the purity and yield of the product.
Second, with phthalimide as the starting material, it is first hydrolyzed to open the ring to form o-carbamoyl benzoic acid. In this step of hydrolysis, it is necessary to select a suitable hydrolyzer to control the reaction conditions. Then, o-carbamoyl benzoic acid reacts with ethylene oxide, and with the help of catalysis, the target product is obtained. The activity and dosage of the catalyst also affect the reaction process.
Third, using benzoic acid as the starting material, first halogenate it to obtain halogenated benzoic acid. When halogenating, the choice of halogenating agent and the solvent for the reaction need to be carefully investigated. Then, when halobenzoic acid meets ethanolamine, under the catalysis of alkali, nucleophilic substitution can be performed, and 2-% hydroxyethylcarbamoyl benzoic acid can also be obtained. The strength of the base and the temperature of the reaction are all related to the quality of the product.
All kinds of synthesis methods have their own advantages. Either the raw materials are easy to obtain, or the reaction conditions are easy to control, or the purity of the product is commendable. However, in actual operation, it is necessary to choose carefully according to the quantity and quality of the required product, as well as the cost and equipment, etc., in order to make the synthesis smooth and achieve the expected effect.
First, it is related to storage. This substance should be stored in a cool, dry and well-ventilated place. Be sure to keep away from fire and heat sources, because it is very likely to cause combustion and explosion in case of open flames and hot topics. When storing, it should also be stored separately from oxidants, acids, alkalis, etc., and must not be mixed in storage to prevent violent chemical reactions from occurring, resulting in danger.
Second, there are risks in the operation process, so be careful. When operating, operators should strictly abide by the operating procedures and wear appropriate protective equipment, such as gas masks, chemical safety glasses, anti-toxic infiltration work clothes, and rubber gloves, to avoid direct contact between the skin and the respiratory tract of the substance. The operation site needs to have good ventilation conditions to prevent its vapor from accumulating in the air. At the same time, care should be taken during the operation to prevent it from leaking into the environment.
Third, the leakage response needs to be well-organized. In the event of a leakage accident, the personnel in the contaminated area of the leakage should be quickly evacuated to a safe area and quarantined to strictly restrict the entry and exit of personnel. Emergency responders should wear self-contained positive pressure breathing apparatus and anti-toxic clothing, and do not let the leakage come into contact with combustible substances (such as wood, paper, oil, etc.). When a small amount of leakage, it can be absorbed by sand, vermiculite or other inert materials; when a large amount of leakage, a dike should be built or dug for containment, covered with foam to reduce steam disasters, and then transferred to a tanker or a special collector with a pump, recycled or transported to a waste treatment site for disposal.
Fourth, the transportation link is also critical. Before transportation, ensure that the packaging is complete and the loading is secure. During transportation, ensure that the container does not leak, collapse, fall or damage. It is strictly forbidden to mix and transport with oxidants, acids, alkalis, food chemicals, etc. During transportation, the transportation vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. During transportation, it should be protected from exposure to the sun, rain and high temperature. Road transportation should follow the prescribed route and do not stop in residential areas and densely populated areas.
Looking at "Tiangong Kaiwu", its detailed processes are described in detail, and it is used in chemical materials. Extrapolating from other organic compounds, 2-% cyanoethoxy phenyl may be used in the preparation of pigments and dyes. Due to the development of dyeing industry in ancient times, many organic compounds can produce brilliant pigments through specific reactions. This compound has a special chemical structure, or can produce bright and long-lasting pigments under specific conditions, which can be used in fabric dyeing to make clothing colorful and satisfy the pursuit of beauty in the world.
Furthermore, it may play a role in the synthesis of some special materials. "Tiangong Kaiwu" records the processing methods of various materials, and this compound may participate in similar processes. For example, in the process of making special paper or leather treatment, as an additive, change the physical and chemical properties of the material. Or enhance the toughness of the paper, making it not easy to break; or improve the softness and water resistance of leather, improve the quality of leather, and meet the needs of different industries for material properties.
Or used in the field of pharmaceutical preparation. Although ancient medicine is different from today's chemical pharmaceuticals, there are also many uses of various compounds to cure diseases and save people. The chemical properties of 2-% cyanoethoxy phenyl, or make it have certain pharmacological activity, if properly processed, compatible, or can be used to treat certain diseases, contribute to the health protection of the ancients.
Although the use of 2-% cyanoethoxy phenyl is not directly stated in Tiangong Kaizhi, it can be inferred that it may have important uses in dyeing, material synthesis, medicine, etc.
Looking at its properties, under normal temperature and pressure, 2-% hydroxyethylaminobenzoic acid is often white to pale yellow crystalline powder. This form makes it easy to handle and handle in many chemical reactions and industrial processes. Because it is powdery, it can be easily measured, mixed, and uniformly blended with other substances to participate in various reactions.
When it comes to solubility, this compound has limited solubility in water. However, it exhibits good solubility in some organic solvents, such as ethanol and acetone. For example, in ethanol, with the increase of temperature, its solubility will increase significantly. This property is of great significance. In the field of organic synthesis, researchers can choose suitable solvents based on this difference in solubility to achieve the dissolution, separation and purification of 2-% hydroxyethyl carbamoylbenzoic acid, laying the foundation for the preparation of high-purity products.
In terms of melting point, the melting point of 2-% hydroxyethyl carbamoylbenzoic acid has been accurately determined to be within a specific range. The melting point is one of the important physical constants of the compound, which is of great significance for the identification of its purity. If the compound is extremely pure, its melting point will be relatively fixed and accurate; if it contains impurities, the melting point will be reduced and the melting range will be widened. Therefore, in the process of production and scientific research, by measuring the melting point, the purity status of 2-% hydroxyethylaminobenzoic acid can be quickly determined.
In addition, the density of 2-% hydroxyethylaminobenzoic acid is also a specific value. The physical property of density is crucial when chemical production involves material measurement, storage and transportation. Knowing its density can accurately calculate the volume and quality of the required material, ensure the smooth progress of the production process, and avoid various problems caused by measurement errors. In conclusion, the physical properties of 2% hydroxyethylaminobenzoic acid, such as its white to pale yellow crystalline powder appearance, specific solubility, melting point, and density, provide a foundation and basis for its application in many fields such as organic synthesis, medicine, and chemical industry.
This compound contains carboxyl groups (-COOH), which are acidic and can neutralize with bases to form corresponding carboxylic salts and water. For example, when reacted with sodium hydroxide (NaOH), the hydrogen atoms in the carboxyl group will be replaced by sodium ions to form 2-% hydroxyethylaminobenzoic acid and water. This reaction is like a new equilibrium achieved by blending acid and base with the rigidity of the base and the softness of the acid.
At the same time, it also contains an amino group (-NH2O). Although the amino group in this compound is affected by neighboring groups and is weakly basic, it can still exhibit alkalinity under certain conditions and react with acids. For example, when reacting with hydrochloric acid (HCl), the amino group will bind hydrogen ions to form positively charged ions.
In addition, the ester group (-COO-) in 2-% hydroxyethylaminobenzoic acid can undergo hydrolysis reaction. Under acidic or basic conditions, the ester group will break and form corresponding acids and alcohols. Under alkaline conditions, hydrolysis is more thorough, resulting in carboxylate and alcohol substances. This hydrolysis reaction is like breaking the shackles of the original structure and deriving new material forms.
Its benzene ring structure also gives it a certain stability, and the benzene ring can undergo substitution reactions, such as halogenation reactions, nitrification reactions, etc. These reactions can introduce different substituents on the benzene ring to expand the uses and properties of the compound, just like putting on a colorful coat and giving it a variety of functions.
From the perspective of reactivity, the compound has its own unique reactivity due to the interaction of various functional groups. The presence of carboxyl groups and amino groups allows the formation of hydrogen bonds between molecules, which affects its physical properties, such as melting point, boiling point, etc. In the field of organic synthesis, these chemical properties provide rich possibilities for the preparation of more complex organic compounds, and can construct organic molecules with diverse structures and unique functions through clever design of reaction paths.
First, take phenols and halogenated ethanol as the basis to combine the two. First take refined phenols, such as phenol, put them in a kettle, and wash them with water several times to remove their impurities. Then take halogenated ethanol, such as bromoethanol, and add them to the kettle slowly by dripping according to the amount. In the meantime, slow down the heat with a slight fire to make the contents of the kettle gently phase, and at the same time keep stirring with bamboo chopsticks to ensure that the two blend evenly. Among them, the halogen atom of halogenated ethanol is active, and it is easy to undergo nucleophilic substitution with the phenyl ring connected to the hydroxyl group of phenol. After a long time, the embryonic form of 2-hydroxyethoxy phenyl ether may be obtained. After distillation, remove its unreacted raw materials and by-products, and a relatively pure product can be obtained.
Second, ethylene oxide and phenol are used as starting materials. First, the phenol is ground into a fine powder, placed in a pottery urn, and ethylene oxide gas is reintroduced. The mouth of the urn is sealed, and the temperature in the urn is heated by the method of water separation, so that the temperature in the urn gradually rises. Ethylene oxide has a ternary ring structure, which is active in nature. When it encounters the hydroxyl group of phenol, it is ring-opened and connected to the phenol, After the reaction is completed, extract it in an organic solvent, such as ether, repeatedly extract it several times, and then steam off the ether to obtain the product.
Third, alcohol and phenyl ether derivatives are used as groups. First, the alcohol is catalyzed by oxidation to obtain the corresponding aldehyde or ketone, and then condensation with phenyl ether derivatives under alkali catalysis. Take ethanol, use copper as a catalyst, and heat it to acetaldehyde. Another phenyl ether derivative is taken, placed in a porcelain kettle with acetaldehyde, and an appropriate amount of alkali, such as potassium hydroxide, is added to slow heat to promote its condensation. After the reaction is completed, neutralize with acid, and then wash with water, dry, rectify and other processes, 2-hydroxyethoxy phenyl ether can also be obtained.
This number method is based on the principles of ancient law, the nature of borrowing, the principle of Hue, or can be prepared 2-hydroxy ethoxy phenyl ether, but the actual operation, still need to carefully observe the physical properties, observe the degree of discipline, in order to achieve its purpose.
Its properties may be unstable. When storing, it should first choose a dry, cool and well-ventilated place. If this medicine encounters moisture, it may cause changes in its properties and its efficacy will be damaged. And if the temperature is too high, it can also cause its qualitative change. Therefore, when avoiding high temperature environment, it should be controlled in a moderate low temperature range, so as to ensure the stability of its chemical properties.
Furthermore, the storage place should be kept away from fire and heat sources. 2-% hydroxyethoxyphenyl ether may be flammable, but near fire is dangerous, which is easy to cause fire and endanger the safety of the surrounding area. At the same time, it also needs to be separated from oxidants, acids and other substances. Due to its active chemical properties, contact with them, or a violent reaction, causing accidents.
As for transportation, it should not be ignored. The packaging must be solid and reliable to prevent package damage and drug outflow due to bumps and collisions. And during transportation, it is also necessary to maintain a suitable environment and keep it dry and cool. The escort must be familiar with its characteristics and emergency methods, and in case of emergencies, it can be properly disposed of in a timely manner. When loading and unloading, it is even more necessary to be careful, handle it with care, and do not damage the packaging.
Only during storage and transportation, strict adherence to all points and comprehensive protection can ensure the quality and safety of 2-% hydroxyethoxyphenyl ether, so that it can play its due role in subsequent applications.

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