(2-Chloroethyl)Benzene

Linshang Chemical

Specifications

HS Code

978047

Chemical Formula C8H9Cl
Molar Mass 140.61 g/mol
Appearance Colorless to light yellow liquid
Odor Aromatic odor
Density 1.069 g/cm³ at 20 °C
Boiling Point 208 - 210 °C
Melting Point -45 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in most organic solvents
Flash Point 80 °C

As an accredited (2-Chloroethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500 - gram bottle packaging for (2 - chloroethyl)benzene chemical.
Storage (2 - chloroethyl)benzene should be stored in a cool, well - ventilated area away from direct sunlight. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents, acids, and bases. Use storage cabinets made of compatible materials, and ensure proper labeling for easy identification and safety compliance.
Shipping (2 - chloroethyl)benzene is shipped in tightly - sealed, corrosion - resistant containers. Transport follows strict hazardous material regulations, ensuring proper handling to prevent spills and environmental or safety risks during transit.
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(2-Chloroethyl)Benzene (2-Chloroethyl)Benzene
General Information
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Frequently Asked Questions

As a leading (2-Chloroethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of (2-chloroethyl) benzene?
(2-Chloroethyl) benzene, which is an organic compound. This substance has the following chemical properties:
First, the property of halogenated hydrocarbons. Due to the presence of chlorine atoms, (2-chloroethyl) benzene can undergo nucleophilic substitution reaction. In aqueous sodium hydroxide solution, the hydroxyl group can replace the chlorine atom as a nucleophilic reagent to generate (2-hydroxyethyl) benzene, which is a common hydrolysis reaction. Under the condition of co-heating the alcohol solution with a strong base, the chlorine atom will eliminate the hydrogen atom on the adjacent carbon atom to form styrene. This reaction can be used to prepare styrene compounds.
Second, the properties of benzene rings. (2-chloroethyl) benzene has aromatic properties and can undergo substitution reactions. For example, under the catalysis of Lewis acid, bromination reaction occurs with bromine to generate o-bromo (2-chloroethyl) benzene or p-bromo (2-chloroethyl) benzene, because the alkyl group on the benzene ring is an o-para-localization group. Under the action of concentrated sulfuric acid and concentrated nitric acid mixed acid, nitration reaction can occur to generate the corresponding nitro compound.
Third, oxidation reaction. (2-chloroethyl) benzene side chain can be oxidized. Under the action of strong oxidant, the side chain can be gradually oxidized to eventually produce benzoic acid and its chlorine-containing derivatives. But the conditions are different, and the products are different.
Fourth, addition reaction. Although the benzene ring is relatively stable, it can also be added under special conditions. For example, under the action of high temperature, high pressure and catalyst, benzene ring can be added to hydrogen to form (2-chloroethyl) cyclohexane.
What are the common synthesis methods of (2-chloroethyl) benzene?
For (2-chloroethyl) benzene, there are three common synthesis methods.
First, benzene and chloroethanol are used as raw materials, and under the condition of acid catalysis, the Fu-gram alkylation reaction is carried out. In this reaction, acid is used as a catalyst, and the electron cloud of the benzene ring is electrophilically substituted with the carbon positive ion of chloroethanol to form (2-chloroethyl) benzene. However, this reaction needs to pay attention to the control of the reaction conditions. If the temperature is too high or the amount of catalyst is improper, it is easy to produce by-products with multiple substitutions, resulting in a decrease in the purity of the product.
Second, it can be obtained by the addition of styrene and hydrogen chloride. Styrene has a carbon-carbon double bond and can be electrophilically added to hydrogen chloride. In general, in the presence of peroxides, the addition of hydrogen chloride to styrene follows the anti-Martensitic rule; if there is no peroxide, the main Martensitic addition product is obtained. This reaction condition is relatively mild and the yield is quite high, but the cost of the raw material styrene may affect the synthesis.
Third, benzyl chloride and ethylene oxide are used as raw materials to react under alkaline conditions. The chlorine atom of benzyl chloride has a certain activity. In the alkaline environment, ethylene oxide opens the ring, and then reacts with benzyl chloride to form (2-chloroethyl) benzene. In this process, the choice and dosage of basic reagents are very critical, which is related to the reaction rate and the selectivity of the product.
All synthesis methods have advantages and disadvantages. In practical application, it is necessary to comprehensively consider the availability of raw materials, cost, product purity and many other factors to choose the optimal method.
What are the industrial applications of (2-chloroethyl) benzene?
(2-Chloroethyl) benzene is widely used in industry. It can be used as an intermediary in organic synthesis and is crucial in the pharmaceutical, pesticide and fragrance industries.
In the field of medicine, it is often an important raw material for the preparation of drugs. Due to its special structure, specific groups can be introduced through a series of chemical reactions to form compounds with pharmacological activity. For example, in the synthesis of some anti-cancer drugs and nervous system drugs, (2-chloroethyl) benzene is often one of the starting materials. Through ingenious reaction design, complex drug molecular structures can be constructed to achieve the effect of treating diseases.
In the pesticide industry, it also has extraordinary performance. It can be chemically converted to prepare pesticides, fungicides and other pesticide products. With its chemical properties, it has the performance of efficient insecticidal and bactericidal, protecting crops from pests and diseases, and ensuring agricultural harvest.
In the manufacture of fragrances, (2-chloroethyl) benzene can be modified and converted to generate compounds with unique aromas. Add a unique flavor to the fragrance formula, or increase the durability and layering of the fragrance, making the fragrance of perfumes, flavors and other products more attractive.
In addition, in the field of polymer materials, (2-chloroethyl) benzene or monomers or modifiers that can be used for polymerization reactions. By participating in the polymerization process, the structure and properties of polymer materials can be changed, such as improving the heat resistance and mechanical properties of materials, expanding the application scope of polymer materials, and playing a role in the manufacturing of plastics, fibers, and many other products.
What are the physical properties of (2-chloroethyl) benzene?
The physical properties of (2-chloroethyl) benzene are quite interesting. This substance is often in a liquid state at room temperature. It is clear and transparent, like a clear spring, without impurities. Its color is pure, almost colorless, like natural water, without the slightest variegation.
Smell it, (2-chloroethyl) benzene emits a special smell, but this smell is neither pungent nor tasteless. It is between the two. Although it is not rich, it is also one of its characteristics.
When it comes to density, compared to water, (2-chloroethyl) benzene is slightly lighter, so it is placed in water and often floats on the water surface, such as oil floating in water, with clear boundaries.
In terms of solubility, (2-chloroethyl) benzene is insoluble in water. However, organic solvents, such as ethanol and ether, can blend with them, just like water and emulsion, without distinction.
Its boiling point is also a key physical property. When it reaches a certain temperature, (2-chloroethyl) benzene will boil and turn into a gaseous state. This boiling point value is relatively stable under specific conditions, which is an important basis for the identification and use of this substance. The melting point of
cannot be ignored either. When the temperature drops to a certain extent, (2-chloroethyl) benzene will change from liquid to solid. This melting point is also one of its inherent physical properties and is of great significance in related research and practical applications.
What are the effects of (2-chloroethyl) benzene on the environment and human health?
The impact of (2-chloroethyl) benzene on the environment and human health is of great concern to the world. This substance is toxic to a certain extent, and its harm to the environment is first seen in the disturbance of ecological balance. In soil, (2-chloroethyl) benzene may inhibit the growth of crops, causing their development to be hindered and harvests to be reduced. Because it is difficult to degrade, it will remain in the soil for a long time, gradually accumulating more and more, harming the soil ecology. And if it enters the water body, it can cause water pollution, poison aquatic organisms, fish may die, and the food chain of the aquatic ecosystem is also destroyed, causing ecological balance to be disrupted.
As for human health, (2-chloroethyl) benzene can be ingested by breathing, skin contact, or diet. After entering the body, it may damage the nervous system, causing dizziness, fatigue, and even affecting cognitive and behavioral abilities. It can also cause damage to the liver, kidneys and other organs, interfere with their normal metabolism and detoxification functions, long-term exposure, or increase the risk of liver and kidney diseases. And it may be carcinogenic. Long-term exposure to this substance environment may increase the risk of cancer, endangering life and health. Therefore, the use and emission of (2-chloroethyl) benzene should be done with caution to protect the environment and human health.
What are the chemical properties of (2-chloroethyl) benzene?
(2-Chloroethyl) benzene is an organic compound with unique chemical properties. Its chemical properties can be viewed from the following points:
In the nucleophilic substitution reaction, (2-chloroethyl) benzene is prone to nucleophilic substitution due to the activity of chlorine atoms. Taking an aqueous solution of sodium hydroxide as an example, when heated, the hydroxyl negative ion acts as a nucleophilic reagent to attack the carbon atom connected to chlorine, and the chlorine atom leaves to form (2-hydroxyethyl) benzene. This reaction mechanism provides an electron pair for the nucleophilic reagent to form a new bond with the substrate, while the chlorine atom leaves with a pair of electrons. The reaction formula is as follows:
\ [C_6H_5CH_2CH_2Cl + NaOH\ xrightarrow {\ Delta} C_6H_5CH_2CH_2OH + NaCl\]
When reacting with sodium alcohol, the anion of alcohol and oxygen has strong nucleophilicity, attacks the carbon atom connected to chlorine, and generates the corresponding ether compound. If reacting with sodium ethanol, ethoxy phenethane can be obtained. The reaction formula is:
\ [C_6H_5CH_2CH_2Cl + C_2H_5ONa\ longrightarrow C_6H_5CH_2CH_2OC_2H_5 + NaCl\]
In the elimination reaction, in the strong alkali alcohol solution, (2-chloroethyl) benzene can be eliminated. Taking potassium hydroxide alcohol solution as an example, when heated, the chlorine atom and the hydrogen atom on the adjacent carbon atom are removed under the action of alkali to form styrene and hydrogen halide. This is the reaction mechanism of E2 elimination. The reaction is completed in one step, and the old bond is broken and the new bond is formed simultaneously. The reaction formula is:
\ [C_6H_5CH_2CH_2Cl + KOH\ xrightarrow {alcohol,\ Delta} C_6H_5CH = CH_2 + KCl + H_2O\]
In addition, the benzene ring of (2-chloroethyl) benzene is aromatic and can undergo electrophilic substitution reaction. The electron cloud density of the benzene ring is high and it is vulnerable to the attack of electrophilic reagents. For example, under the catalysis of ferric chloride, bromine reacts with bromine to form o-bromo (2-chloroethyl) benzene and p-bromo (2-chloroethyl) benzene. In this reaction, bromine molecules are polarized under the action of catalysts, and the positively charged end attacks the benzene ring to form an intermediate, and then loses protons to form products. The reaction formula is:
\ [C_6H_5CH_2CH_2Cl + Br_2\ xrightarrow {FeCl_3} o - BrC_6H_4CH_2CH_2Cl + p - BrC_6H_4CH_2CH_2Cl + HBr\]
(2-chloroethyl) benzene is rich in chemical properties, nucleophilic substitution, elimination and electrophilic substitution of the benzene ring. It is widely used in the field of organic synthesis and can prepare a variety of organic compounds.
What are the common uses of (2-chloroethyl) benzene?
(2-Chloroethyl) benzene, commonly known as β-chloroethylbenzene, has the following common uses.
First, in the field of organic synthesis, it is a key intermediate. Other organic compounds can be derived through many reactions. For example, when interacting with nucleophiles, chlorine atoms can be replaced. Like reacting with sodium alcohol, corresponding ether compounds can be formed, and this reaction follows the nucleophilic substitution mechanism. With this, complex organic molecular structures can be constructed, which are widely used in drug synthesis, material chemistry and other fields. When drug research and development, (2-chloroethyl) benzene is often used as a starting material and through a series of reactions, drug molecules with specific biological activities can be prepared.
Second, it also contributes to the field of materials science. Can participate in the synthesis of polymer materials. For example, through polymerization, its structural units are introduced into the polymer chain, thereby giving the material unique properties. Can change the solubility, thermal stability or mechanical properties of the material. For example, if the (2-chloroethyl) benzene structural unit is introduced into the polymer, it may improve the solubility of the polymer to specific solvents, and has practical value in the preparation of materials such as coatings and adhesives.
Third, in the fragrance industry, (2-chloroethyl) benzene can be used as a raw material for synthesizing fragrances. Due to its unique chemical structure, after appropriate reaction and transformation, compounds with special aromas can be generated. After modification and reaction, fragrance ingredients with fresh and unique aroma can be obtained, which can be used to prepare perfumes, flavors and other products to increase their aroma level and uniqueness.
In short, (2-chloroethyl) benzene has important uses in organic synthesis, materials science, fragrance industry and other fields, and is an indispensable raw material for the development of the chemical industry.
What are the synthesis methods of (2-chloroethyl) benzene?
There are several ways to make (2-chloroethyl) benzene. One is to use benzene and chloroethanol as raw materials, and in the presence of appropriate catalysts, the two will undergo a substitution reaction. This reaction requires the selection of suitable catalysts, such as certain metal salts or specific organic compounds, to promote the smooth progress of the reaction. During the reaction, temperature control and pressure control are required to make the reaction proceed in the direction of generating (2-chloroethyl) benzene.
The second can be obtained by adding styrene and hydrogen chloride. Styrene has an unsaturated double bond. When exposed to hydrogen chloride, under suitable reaction conditions, the double bond is opened, and the hydrogen and chlorine atoms of hydrogen chloride are added to the carbon atoms at both ends of the double bond to form (2-chloroethyl) benzene. This process also requires attention to the reaction conditions, such as temperature, pressure and catalyst. The choice of catalyst is crucial to the reaction rate and product selectivity.
Or first react benzene with ethylene oxide to form an intermediate, and then the intermediate reacts with the chlorinating agent. After a series of conversions, (2-chloroethyl) benzene can also be obtained. In this method, the reaction with ethylene oxide and the subsequent reaction steps with chlorinating agents require fine regulation of the reaction conditions to ensure that each step of the reaction proceeds as expected to obtain higher yield and purity of (2-chloroethyl) benzene. In short, all synthetic methods have their own advantages and disadvantages. In practical application, when considering many factors such as raw material availability, cost, yield and product purity, the choice is made.
What are the environmental effects of (2-chloroethyl) benzene?
(2-Chloroethyl) benzene, its impact on the environment is quite complex. If this substance is dispersed in the atmosphere, or migrates with the airflow, it may also be gradually eliminated by photolysis. In water bodies, it may be insoluble, but it can be attached to suspended particles, causing sedimentation in bottom mud, long-term accumulation, harming aquatic organisms.
Its toxicity to aquatic organisms should not be underestimated, or disturbing its normal physiological functions, such as development and reproduction. In the food chain, due to biological enrichment, lower organisms gradually accumulate in higher organisms, eventually endangering the top organisms and causing ecological imbalance.
If the soil is stained by it, or stagnates on the soil surface, or seeps into the deep layer, it will affect the activity of soil microorganisms, damage the soil ecological structure, and then hinder the absorption of nutrients and water by plant roots, causing plant growth to be trapped, stunted, or cause plant diseases and death.
And (2-chloroethyl) benzene is volatile and escapes in the air. If inhaled, it may cause respiratory irritation and damage the lungs; through skin contact, it may also penetrate into the human body, affecting the function of the nervous system, liver and other organs.
Therefore, when it is produced, used and disposed of, it should be done with caution, in accordance with strict environmental protection regulations, to control its harm to the environment and people, and to maintain ecological balance and people's well-being.
What should I pay attention to when storing and transporting (2-chloroethyl) benzene?
For (2-chloroethyl) benzene, many matters must be paid attention to when storing and transporting.
One is related to storage. This substance should be placed in a cool and ventilated warehouse. Because of the cool and ventilated place, it can avoid the high temperature causing its volatilization to intensify, or the chemical reaction caused by excessive temperature. The temperature of the warehouse should be controlled in a suitable range, and it should not be overheated. And keep away from fire and heat sources. Open flames and hot topics can easily cause it to burn or even explode, which is a serious safety hazard. At the same time, it should be stored separately from oxidants and edible chemicals, and must not be mixed. Because the oxidizing agent may react with (2-chloroethyl) benzene and mix with edible chemicals, if there is leakage, it may cause serious pollution and endanger food safety.
Second, about transportation. Be sure to ensure that the packaging is complete and sealed before transportation. If the packaging is damaged, (2-chloroethyl) benzene is easy to leak, which not only causes material loss, but also leaks may pollute the environment, which is very harmful. During transportation, strictly follow the prescribed route and do not stop in densely populated areas, residential areas, etc. This is due to accidental leakage or accident of (2-chloroethyl) benzene, which will pose a threat to many lives in densely populated areas. Transport vehicles must also be equipped with the appropriate variety and quantity of fire fighting equipment and leakage emergency treatment equipment, in case of emergency, in case of emergencies can be responded to in time to reduce harm.
In this way, when storing and transporting (2-chloroethyl) benzene, pay careful attention to the above items to ensure safety.