Linshang Chemical
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2-(Chloromethyl)-1,4-Dimethoxybenzene
Linshang Chemical
|
HS Code |
733791 |
| Chemical Formula | C9H11ClO2 |
| Molar Mass | 186.635 g/mol |
| Appearance | Typically a colorless to light - yellow liquid or solid |
| Boiling Point | Approximately 240 - 245 °C |
| Melting Point | Around 38 - 42 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone, dichloromethane |
| Density | Approx. 1.166 g/cm³ |
| Flash Point | Around 112 °C |
| Odor | Characteristic, pungent |
As an accredited 2-(Chloromethyl)-1,4-Dimethoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2-(chloromethyl)-1,4 -dimethoxybenzene packaged in a sealed, chemical - resistant bottle. |
| Storage | 2-(Chloromethyl)-1,4 -dimethoxybenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass. Store it separately from oxidizing agents and reactive substances to prevent potential chemical reactions. |
| Shipping | 2-(Chloromethyl)-1,4 -dimethoxybenzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring proper labeling, secure packaging to prevent leakage during transit. |
Competitive 2-(Chloromethyl)-1,4-Dimethoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-(Chloromethyl)-1,4-Dimethoxybenzene in China?
As a trusted 2-(Chloromethyl)-1,4-Dimethoxybenzene manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-(Chloromethyl)-1,4-Dimethoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 2- (chloromethyl) -1,4-dimethoxybenzene?
2-%28chloromethyl%29-1%2C4-dimethoxybenzene is 2- (chloromethyl) -1,4-dimethoxybenzene, which is widely used. In the field of organic synthesis, it can be called an important intermediate.
It can be used to construct a variety of complex organic compounds. For example, with its chloromethyl activity, it can react with many nucleophiles to achieve the construction of carbon-carbon bonds or carbon-heteroatomic bonds. In the fine chemical industry, it also plays a key role. In the preparation of some special functional materials, such as photoelectric materials, 2- (chloromethyl) -1,4-dimethoxybenzene can be used as a starting material to participate in the reaction, imparting specific properties to the material.
In the field of medicinal chemistry, it also has potential applications. It can be used as a key intermediate for the synthesis of biologically active compounds. After subsequent chemical modification, or drug molecules with pharmacological activity can be obtained, opening up new paths for pharmaceutical research and development.
In the field of fragrance synthesis, its unique chemical structure can also become an important fragment for the construction of special aroma compounds, providing novel synthesis ideas and raw material selection for the creation of fragrances, giving fragrances unique odor characteristics. In short, 2 - (chloromethyl) -1,4 - dimethoxy benzene plays an indispensable role in many fields such as organic synthesis, fine chemistry, medicine and fragrances, and promotes technological innovation and development in various fields.
It can be used to construct a variety of complex organic compounds. For example, with its chloromethyl activity, it can react with many nucleophiles to achieve the construction of carbon-carbon bonds or carbon-heteroatomic bonds. In the fine chemical industry, it also plays a key role. In the preparation of some special functional materials, such as photoelectric materials, 2- (chloromethyl) -1,4-dimethoxybenzene can be used as a starting material to participate in the reaction, imparting specific properties to the material.
In the field of medicinal chemistry, it also has potential applications. It can be used as a key intermediate for the synthesis of biologically active compounds. After subsequent chemical modification, or drug molecules with pharmacological activity can be obtained, opening up new paths for pharmaceutical research and development.
In the field of fragrance synthesis, its unique chemical structure can also become an important fragment for the construction of special aroma compounds, providing novel synthesis ideas and raw material selection for the creation of fragrances, giving fragrances unique odor characteristics. In short, 2 - (chloromethyl) -1,4 - dimethoxy benzene plays an indispensable role in many fields such as organic synthesis, fine chemistry, medicine and fragrances, and promotes technological innovation and development in various fields.
What are the physical properties of 2- (chloromethyl) -1,4-dimethoxybenzene
2-%28chloromethyl%29-1%2C4-dimethoxybenzene that is 2- (chloromethyl) -1,4-dimethoxybenzene, its physical properties are as follows:
This substance is mostly colorless to light yellow liquid at room temperature, and it has a certain fluidity. It has a special aromatic smell, but this smell is not pleasant, and it can be inhaled too much or irritated to the human senses. Its melting point is quite critical, and the melting point is about a relatively low range, which makes it difficult to solidify at room temperature and still exists in a liquid state; the boiling point is relatively high, indicating that more heat needs to be applied to make it boil into a gaseous state.
In terms of density, it is slightly heavier than water. If it is placed in water, it can be seen that it sinks to the bottom of the water. In terms of solubility, it exhibits good solubility in organic solvents such as ethanol and ether, and can be miscible with them; however, it has poor solubility in water. Due to its molecular structure characteristics, it is difficult to form an effective interaction with water molecules, so it is difficult to dissolve in water.
In addition, 2- (chloromethyl) -1,4-dimethoxy benzene has weak volatility and is difficult to evaporate rapidly in air, which makes it relatively stable during storage and use, and is not easy to be lost due to rapid volatilization or cause safety hazards. However, when using it, it is still necessary to pay attention to appropriate protection, because it has certain irritation, contact with skin and eyes, or cause discomfort.
This substance is mostly colorless to light yellow liquid at room temperature, and it has a certain fluidity. It has a special aromatic smell, but this smell is not pleasant, and it can be inhaled too much or irritated to the human senses. Its melting point is quite critical, and the melting point is about a relatively low range, which makes it difficult to solidify at room temperature and still exists in a liquid state; the boiling point is relatively high, indicating that more heat needs to be applied to make it boil into a gaseous state.
In terms of density, it is slightly heavier than water. If it is placed in water, it can be seen that it sinks to the bottom of the water. In terms of solubility, it exhibits good solubility in organic solvents such as ethanol and ether, and can be miscible with them; however, it has poor solubility in water. Due to its molecular structure characteristics, it is difficult to form an effective interaction with water molecules, so it is difficult to dissolve in water.
In addition, 2- (chloromethyl) -1,4-dimethoxy benzene has weak volatility and is difficult to evaporate rapidly in air, which makes it relatively stable during storage and use, and is not easy to be lost due to rapid volatilization or cause safety hazards. However, when using it, it is still necessary to pay attention to appropriate protection, because it has certain irritation, contact with skin and eyes, or cause discomfort.
What are the synthesis methods of 2- (chloromethyl) -1,4-dimethoxybenzene
To prepare 2 - (chloromethyl) -1,4 - dimethoxybenzene, there are various methods.
First, it can be obtained from 1,4 - dimethoxybenzene by chloromethylation. This reaction requires paraformaldehyde and hydrogen chloride as raw materials and is carried out in the presence of specific catalysts such as zinc salt or tin salt. The process is as follows: first place 1,4 - dimethoxybenzene in a suitable solvent, such as dichloromethane, stir well, slowly add paraformaldehyde, and then pass into dry hydrogen chloride gas to react at a certain temperature. This reaction condition is mild and the yield is acceptable, but attention needs to be paid to controlling the reaction process to avoid excessive chloromethylation.
Second, 1,4-dimethoxybenzyl alcohol can also be used as raw material and prepared by chlorination reaction. Select suitable chlorination reagents, such as thionyl chloride, phosphorus trichloride, etc. If thionyl chloride is used, dissolve 1,4-dimethoxybenzyl alcohol in an appropriate amount of solvent, such as pyridine, add thionyl chloride dropwise under an ice bath, and then rise to room temperature for reaction. The method is simple to operate, the product is easy to separate and purify, and the thionyl chloride reaction generates sulfur dioxide and hydrogen chloride gas, which is easy to remove.
Or, with 1,4-dimethoxybenzoic acid as the starting material, first reduce to 1,4-dimethoxybenzyl alcohol, and then chlorinate. Strong reducing agents such as lithium aluminum hydride can be used for reduction. Although the reduction effect is good, lithium aluminum hydride is active and requires caution in operation. The subsequent chlorination steps are similar to the above method using 1,4-dimethoxybenzyl alcohol as raw material.
All methods have advantages and disadvantages. In actual synthesis, the appropriate method should be carefully selected according to factors such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product.
First, it can be obtained from 1,4 - dimethoxybenzene by chloromethylation. This reaction requires paraformaldehyde and hydrogen chloride as raw materials and is carried out in the presence of specific catalysts such as zinc salt or tin salt. The process is as follows: first place 1,4 - dimethoxybenzene in a suitable solvent, such as dichloromethane, stir well, slowly add paraformaldehyde, and then pass into dry hydrogen chloride gas to react at a certain temperature. This reaction condition is mild and the yield is acceptable, but attention needs to be paid to controlling the reaction process to avoid excessive chloromethylation.
Second, 1,4-dimethoxybenzyl alcohol can also be used as raw material and prepared by chlorination reaction. Select suitable chlorination reagents, such as thionyl chloride, phosphorus trichloride, etc. If thionyl chloride is used, dissolve 1,4-dimethoxybenzyl alcohol in an appropriate amount of solvent, such as pyridine, add thionyl chloride dropwise under an ice bath, and then rise to room temperature for reaction. The method is simple to operate, the product is easy to separate and purify, and the thionyl chloride reaction generates sulfur dioxide and hydrogen chloride gas, which is easy to remove.
Or, with 1,4-dimethoxybenzoic acid as the starting material, first reduce to 1,4-dimethoxybenzyl alcohol, and then chlorinate. Strong reducing agents such as lithium aluminum hydride can be used for reduction. Although the reduction effect is good, lithium aluminum hydride is active and requires caution in operation. The subsequent chlorination steps are similar to the above method using 1,4-dimethoxybenzyl alcohol as raw material.
All methods have advantages and disadvantages. In actual synthesis, the appropriate method should be carefully selected according to factors such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product.
What should be paid attention to when storing and transporting 2- (chloromethyl) -1,4-dimethoxybenzene?
2-%28chloromethyl%29-1%2C4-dimethoxybenzene is 2- (chloromethyl) -1,4-dimethoxybenzene. When storing and transporting this substance, many matters need to be paid attention to.
First talk about storage. This substance has a certain chemical activity and is easily reacted with substances in the surrounding environment, so it should be placed in a cool, dry and well ventilated place. Do not store it in a high temperature or humid place, because high temperature will promote its reaction rate to speed up, and humid environment may cause adverse reactions such as hydrolysis. And keep away from fire and heat sources to prevent open flames, because it may be flammable. When storing, it should be stored separately from oxidizing agents, acids, bases, etc., and must not be mixed in storage to prevent violent chemical reactions and even cause danger. There are also requirements for storage containers, which must be made of corrosion-resistant materials to ensure good sealing and prevent leakage. At the same time, clear warning signs should be posted in the storage area to remind personnel to pay attention.
As for transportation, it should not be taken lightly. Before transportation, ensure that the packaging is complete and the loading is secure. During transportation, the relevant transportation regulations must be strictly adhered to, and the speed should not be too fast to avoid bumps and vibrations to prevent damage to the packaging. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During transportation, always pay attention to the condition of the goods. Once any abnormalities, such as leaks, are detected, effective measures should be taken immediately. And transportation personnel need to undergo professional training, familiar with the characteristics of the substance and emergency treatment methods to ensure the safety of the transportation process.
First talk about storage. This substance has a certain chemical activity and is easily reacted with substances in the surrounding environment, so it should be placed in a cool, dry and well ventilated place. Do not store it in a high temperature or humid place, because high temperature will promote its reaction rate to speed up, and humid environment may cause adverse reactions such as hydrolysis. And keep away from fire and heat sources to prevent open flames, because it may be flammable. When storing, it should be stored separately from oxidizing agents, acids, bases, etc., and must not be mixed in storage to prevent violent chemical reactions and even cause danger. There are also requirements for storage containers, which must be made of corrosion-resistant materials to ensure good sealing and prevent leakage. At the same time, clear warning signs should be posted in the storage area to remind personnel to pay attention.
As for transportation, it should not be taken lightly. Before transportation, ensure that the packaging is complete and the loading is secure. During transportation, the relevant transportation regulations must be strictly adhered to, and the speed should not be too fast to avoid bumps and vibrations to prevent damage to the packaging. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During transportation, always pay attention to the condition of the goods. Once any abnormalities, such as leaks, are detected, effective measures should be taken immediately. And transportation personnel need to undergo professional training, familiar with the characteristics of the substance and emergency treatment methods to ensure the safety of the transportation process.
What are the effects of 2- (chloromethyl) -1,4-dimethoxybenzene on the environment and human body?
2-%28chloromethyl%29-1%2C4-dimethoxybenzene is 2- (chloromethyl) -1,4-dimethoxybenzene, which has considerable effects on the environment and human body.
First of all, its impact on the environment. If 2- (chloromethyl) -1,4-dimethoxybenzene is released in the environment, it has certain chemical activity, or it migrates and transforms between soil and water bodies. In soil, or interacts with soil particles, it affects the activity and composition of soil microbial communities. Soil microorganisms play a key role in many aspects such as soil fertility maintenance and material circulation. This compound may inhibit the growth of some beneficial microorganisms and destroy the balance of soil ecology. In water bodies, it may affect aquatic organisms. Such as fish, plankton, etc., or due to exposure to this compound, physiological function is impaired. Or cause abnormal behavior of fish such as respiration and reproduction. In the long run, it may disrupt the food chain and biodiversity of the entire aquatic ecosystem.
Re-discuss its impact on the human body. 2 - (chloromethyl) -1,4 -dimethoxybenzene may be potentially toxic. It can enter the human body through respiratory tract, skin contact or accidental ingestion. Inhalation through the respiratory tract, or irritation of respiratory mucosa, causing uncomfortable symptoms such as cough and asthma. If exposed through skin, or cause allergic reactions to the skin, such as itching, redness and swelling. The harm of accidental ingestion is particularly serious. After entering the human body, or in the process of metabolism in the body, it interacts with biological macromolecules such as proteins and nucleic acids, which interferes with the normal physiological functions of cells. Or there is a latent risk of mutagenesis and carcinogenesis, and in the long run, it poses a great threat to human health.
In summary, 2- (chloromethyl) -1,4-dimethoxybenzene is potentially harmful to the environment and human health. During its production and use, it should be handled with caution to prevent adverse effects on the environment and human body.
First of all, its impact on the environment. If 2- (chloromethyl) -1,4-dimethoxybenzene is released in the environment, it has certain chemical activity, or it migrates and transforms between soil and water bodies. In soil, or interacts with soil particles, it affects the activity and composition of soil microbial communities. Soil microorganisms play a key role in many aspects such as soil fertility maintenance and material circulation. This compound may inhibit the growth of some beneficial microorganisms and destroy the balance of soil ecology. In water bodies, it may affect aquatic organisms. Such as fish, plankton, etc., or due to exposure to this compound, physiological function is impaired. Or cause abnormal behavior of fish such as respiration and reproduction. In the long run, it may disrupt the food chain and biodiversity of the entire aquatic ecosystem.
Re-discuss its impact on the human body. 2 - (chloromethyl) -1,4 -dimethoxybenzene may be potentially toxic. It can enter the human body through respiratory tract, skin contact or accidental ingestion. Inhalation through the respiratory tract, or irritation of respiratory mucosa, causing uncomfortable symptoms such as cough and asthma. If exposed through skin, or cause allergic reactions to the skin, such as itching, redness and swelling. The harm of accidental ingestion is particularly serious. After entering the human body, or in the process of metabolism in the body, it interacts with biological macromolecules such as proteins and nucleic acids, which interferes with the normal physiological functions of cells. Or there is a latent risk of mutagenesis and carcinogenesis, and in the long run, it poses a great threat to human health.
In summary, 2- (chloromethyl) -1,4-dimethoxybenzene is potentially harmful to the environment and human health. During its production and use, it should be handled with caution to prevent adverse effects on the environment and human body.
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