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2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene

Linshang Chemical

Specifications

HS Code

877308

Chemical Formula C8H5ClF4
Molecular Weight 214.57
Solubility In Water Low solubility, likely less than 1 g/L due to non - polar nature
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene

As an accredited 2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2-(chloromethyl)-4-fluoro-1-(trifluoromethyl)benzene in sealed chemical - grade bottles.
Storage 2-(Chloromethyl)-4-fluoro-1-(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents, bases, and reactive materials to avoid potential chemical reactions.
Shipping 2-(Chloromethyl)-4-fluoro-1-(trifluoromethyl)benzene is shipped in accordance with chemical transportation regulations. It's carefully packaged in suitable containers to prevent leakage during transit to ensure safety.
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2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene 2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene
General Information
Where to Buy 2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene in China?
As a trusted 2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-(Chloromethyl)-4-Fluoro-1-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene?
2-%28chloromethyl%29-4-fluoro-1-%28trifluoromethyl%29benzene, the Chinese name is 2 - (chloromethyl) -4 -fluoro-1 - (trifluoromethyl) benzene. This substance is used for this purpose, and it is often used in the synthesis process. Due to the characteristics of chloromethyl, fluorine atoms and trifluoromethyl atoms in the molecule, it can be used for polymorphism, such as nuclear substitution, even anti-benzene, and other compounds. It is also a molecular framework with biological activity. For example, it can be used in the synthesis of specific anti-tumor compounds. By virtue of its specific characteristics, it can target specific receptors or enzymes of cancer cells, and dry the physiological processes such as cell proliferation and differentiation.
It is also indispensable in the field of cancer. It can be used as a raw material for the synthesis of new types of bacteria and bacteria. Its special properties can make the synthesized product have high performance, high activity and low toxicity. For example, it can be used to solve a specific damage or replace it. It has precise effect, high efficiency, and little impact on the environment and non-target organisms, which meets the needs of the development of the color of the next generation.
Furthermore, in the material department, 2 - (chloromethyl) -4 - fluoro-1 - (trifluoromethyl) benzene is also available. Due to the introduction of fluorine atoms and trifluoromethyl, the properties of the material can be improved. For example, in the synthesis of polymer materials, the addition of this compound can improve the weather resistance, chemical resistance and surface properties of the material. So that polymer materials can maintain good physical and chemical properties under poor conditions, and can be widely used in high-end applications such as aerospace and sub-devices.
What are the physical properties of 2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene
2-%28chloromethyl%29-4-fluoro-1-%28trifluoromethyl%29benzene, the Chinese name is 2 - (chloromethyl) -4 -fluoro-1 - (trifluoromethyl) benzene. This physical property is important, and it is important in chemical research and engineering.
In its physical properties, the outer color is often the color of the liquid. Under the eyes, it has flow properties, and it can be cleared under light. Smell it, there is a special aromatic smell, but this smell cannot be ignored, because it is irritating to the respiratory tract or the respiratory tract.

< and boiling, the melting phase is low, and the liquid is often under the pressure. Due to factors such as molecular force, the boiling temperature can vaporize the substance at a specific temperature. This property is very important in chemical operations such as fractionation and extraction.
In terms of solubility, it is soluble in soluble molecules such as ethanol and ether. Due to the principle of similar phase solubility, its molecules are compatible with soluble molecules. However, the solubility in water is not good. Because of the solubility of the substance, the water molecule acts as a force to overcome the strong water molecules, so it is soluble.
Density is also important for physical properties. Its density is similar to that of water. If it is used in operations such as liquid separation, it can be divided into water phases according to this characteristic.
In addition, the property of this object also needs to be considered. There is a certain property under normal conditions. The preservation needs to be kept secret and placed in order to avoid loss or safety. In addition, understanding its physical rationality has implications for synthesis, storage, storage, and use.
What are the synthesis methods of 2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene
There are several ways to prepare 2 - (chloromethyl) -4 - fluoro-1 - (trifluoromethyl) benzene.
First, aromatic hydrocarbons containing appropriate substituents can be used as starting materials. Benzene derivatives with corresponding fluorine and trifluoromethyl substitutions can be taken first, and chloromethyl can be introduced under specific reaction conditions. For example, 4 - fluoro-1 - (trifluoromethyl) benzene is used as a substrate and reacts with chloromethylating reagents such as chloromethyl ether in the presence of appropriate catalysts. This reaction requires attention to the control of reaction conditions. Temperature and catalyst dosage all affect the reaction process and product yield. If the temperature is too high, or the side reaction increases, the purity of the product will be reduced; improper amount of catalyst will also change the reaction rate and selectivity.
Second, the target molecule can be constructed through multi-step reaction. The benzene ring structure containing fluorine and trifluoromethyl is prepared first, and then chloromethyl is gradually introduced. For example, fluorine atoms are introduced at specific positions in the benzene ring through halogenation reaction, and then trifluoromethyl is introduced in a suitable method, and finally chloromethylation is carried out. Although this route has many steps, each step of the reaction can be more selective, which helps to improve the purity of the product. However, the multi-step reaction also brings the problem of complicated operation and reduced total yield. The reaction sequence and conditions need to be carefully planned to optimize the entire synthesis process.
Third, transition metal catalysis can also be used. For example, transition metal complexes such as palladium and copper are used as catalysts to react halogenated aromatics containing fluorine and trifluoromethyl with chloromethylation reagents in the presence of appropriate ligands and bases. Such methods usually have the advantages of mild reaction conditions and high selectivity, but the cost of transition metal catalysts is higher, and the separation and recovery of catalysts after the reaction is also a problem to be considered. In actual synthesis, the advantages and disadvantages of each method need to be comprehensively weighed, and the most suitable synthesis path should be selected according to factors such as raw material availability, cost, product purity and yield.
2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene during storage and transportation
2-%28chloromethyl%29-4-fluoro-1-%28trifluoromethyl%29benzene, that is, 2 - (chloromethyl) - 4 - fluoromethyl - 1 - (trifluoromethyl) benzene. When storing and transporting this product, many matters must be paid attention to.
Safety is the first priority. Because it may be toxic and irritating, contact can cause human damage. When operating, protective clothing, gloves, goggles and gas masks must be worn to ensure the safety of personnel.
This is the second time for packaging. Choose a well-sealed packaging material to prevent leakage. Commonly used glass or metal containers, be sure to check their integrity before packaging, and post a warning mark as required to indicate the dangerous nature.
Furthermore, the storage environment. It should be stored in a cool and ventilated warehouse, away from fire and heat sources. The storage temperature should be controlled in an appropriate range to avoid direct sunlight. Due to high temperature and light, it may decompose or chemically react. At the same time, it should not be mixed with oxidants, acids, alkalis, etc., to prevent dangerous interactions.
When transporting, it is also necessary to strictly abide by the regulations. Choose transportation enterprises and vehicles with corresponding qualifications, and ensure that the container is stable during transportation to avoid collisions and vibrations. If it is long-distance transportation, the packaging condition should also be checked regularly. If a leak is found, emergency measures should be taken immediately.
In conclusion, 2 - (chloromethyl) - 4 - fluoromethyl - 1 - (trifluoromethyl) benzene is a top priority during storage and transportation. From personnel protection, packaging materials, storage environment, and transportation specifications, relevant requirements must be strictly followed to ensure a smooth and safe process and avoid accidents.
What is the market price of 2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene?
We have not obtained the exact number of 2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene on the market. However, if you want to know the quality of this product, you can find the supplier of this chemical product. This compound is often in the field of chemical synthesis, and its quality depends on the product, quantity, supplier and market conditions.
There are general chemical suppliers in the market, such as Sigma - Aldrich, Alfa Aesar, etc. Their projects may be available for their official use. In addition, if the buyer requests a large quantity, he may be able to get the benefit of discounts.
And the quality of the chemical product is often different. The quality of raw materials, the quality of manufacturing, and the supply and demand can all make it rise and fall. Therefore, if you want to know the market price of 2- (chloromethyl) -4-fluoro-1- (trifluoromethyl) benzene and its suppliers, or according to the example of recent transactions, you can only get the price.