Linshang Chemical
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2-Fluoro-3-Chloronitrobenzene
Linshang Chemical
|
HS Code |
297799 |
| Chemical Formula | C6H3ClFNO2 |
| Appearance | Yellow to light brown liquid |
| Boiling Point | 222 - 224 °C |
| Melting Point | 2 - 4 °C |
| Density | 1.495 g/mL at 25 °C |
| Flash Point | 103 °C |
| Solubility | Insoluble in water, soluble in organic solvents like ethanol, ether |
| Vapor Pressure | Low vapor pressure |
| Stability | Stable under normal conditions, but reacts with strong oxidizing agents |
As an accredited 2-Fluoro-3-Chloronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250g of 2 - fluoro - 3 - chloronitrobenzene packaged in a sealed glass bottle. |
| Storage | 2 - fluoro - 3 - chloronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Store separately from oxidizing agents, reducing agents, and bases to prevent chemical reactions. Follow local safety regulations for proper storage. |
| Shipping | 2 - fluoro - 3 - chloronitrobenzene is a chemical. For shipping, it must be packaged in accordance with hazardous material regulations. Use appropriate containers to prevent leakage during transportation to ensure safety. |
Competitive 2-Fluoro-3-Chloronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Fluoro-3-Chloronitrobenzene in China?
As a trusted 2-Fluoro-3-Chloronitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Fluoro-3-Chloronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-fluoro-3-chloronitrobenzene?
2-Fluoro-3-chloronitrobenzene is also an organic compound. Its main uses are quite extensive, and its use in the chemical industry is particularly important.
One of them is an intermediate for organic synthesis. Because its molecular structure contains specific functional groups such as fluorine, chlorine and nitro, it can participate in a variety of chemical reactions, such as nucleophilic substitution reactions. Through such reactions, chemists can introduce other groups into molecules to prepare various organic compounds with special properties and uses. For example, the synthesis of pharmaceutical intermediates with specific structures lays the foundation for the development of new drugs; in the creation of pesticides, pesticide ingredients with high insecticidal, bactericidal or herbicidal activities can also be prepared through a series of reactions using this as a raw material.
Second, it has also contributed to the field of materials science. Due to its structural characteristics, it can participate in the preparation of functional materials through specific synthesis paths and reactions. For example, in the synthesis process of optoelectronic materials, it can be skillfully chemically modified to become a material component with specific optoelectronic properties, which will help the development of optoelectronic devices such as Light Emitting Diode and solar cells.
Third, it also plays a key role in the field of dye synthesis. With its unique structure, through a series of chemical reactions, specific chromophore groups can be constructed, resulting in bright-colored and stable dyes, which are widely used in textiles, printing and dyeing and other industries, giving fabrics a rich and colorful color.
To sum up, 2-fluoro-3-chloronitrobenzene plays an indispensable and important role in many fields such as organic synthesis, materials science and dye synthesis, and is of great significance in promoting the development of the chemical industry and related fields.
One of them is an intermediate for organic synthesis. Because its molecular structure contains specific functional groups such as fluorine, chlorine and nitro, it can participate in a variety of chemical reactions, such as nucleophilic substitution reactions. Through such reactions, chemists can introduce other groups into molecules to prepare various organic compounds with special properties and uses. For example, the synthesis of pharmaceutical intermediates with specific structures lays the foundation for the development of new drugs; in the creation of pesticides, pesticide ingredients with high insecticidal, bactericidal or herbicidal activities can also be prepared through a series of reactions using this as a raw material.
Second, it has also contributed to the field of materials science. Due to its structural characteristics, it can participate in the preparation of functional materials through specific synthesis paths and reactions. For example, in the synthesis process of optoelectronic materials, it can be skillfully chemically modified to become a material component with specific optoelectronic properties, which will help the development of optoelectronic devices such as Light Emitting Diode and solar cells.
Third, it also plays a key role in the field of dye synthesis. With its unique structure, through a series of chemical reactions, specific chromophore groups can be constructed, resulting in bright-colored and stable dyes, which are widely used in textiles, printing and dyeing and other industries, giving fabrics a rich and colorful color.
To sum up, 2-fluoro-3-chloronitrobenzene plays an indispensable and important role in many fields such as organic synthesis, materials science and dye synthesis, and is of great significance in promoting the development of the chemical industry and related fields.
What are the physical properties of 2-fluoro-3-chloronitrobenzene?
2-Fluoro-3-chloronitrobenzene is one of the organic compounds. It has unique physical properties and is described by you today.
First of all, its shape and taste. At room temperature, 2-fluoro-3-chloronitrobenzene is mostly liquid and has a special odor. However, this smell is not pleasant, it is really irritating, and it may cause discomfort if smelled.
Times and boiling point and melting point. The boiling point is related to the temperature at which it changes from liquid to gaseous state. The boiling point of 2-fluoro-3-chloronitrobenzene is quite high, due to the intermolecular forces. There is a van der Waals force between molecules, which requires more energy to overcome this force, so as to realize the phase transition. As for the melting point, it also depends on the molecular structure and interaction. Under a specific temperature, this substance can be converted from solid to liquid.
Furthermore, solubility is also an important physical property. In water, the solubility of 2-fluoro-3-chloronitrobenzene is very small. Because its molecular polarity is quite different from that of water, water is a strongly polar molecule, while the polarity of 2-fluoro-3-chloronitrobenzene is relatively weak. According to the principle of "similar miscibility", the two are difficult to dissolve. However, in organic solvents, such as ethanol, ether, etc., its solubility is better. The molecular polarity of organic solvents is similar to that of 2-fluoro-3-chloronitrobenzene, and weak interactions can be formed between molecules to promote its dissolution.
In addition, the density cannot be ignored. 2-fluoro-3-chloronitrobenzene has a higher density than water. If it is mixed with water, it can be seen to sink to the bottom after standing. This density characteristic is important in many chemical operations and separation processes.
In summary, the physical properties of 2-fluoro-3-chloronitrobenzene, such as state, odor, melting point, solubility, and density, are determined by its molecular structure and intermolecular interactions, and these properties need to be carefully considered when applied in chemical engineering, scientific research, and other fields.
First of all, its shape and taste. At room temperature, 2-fluoro-3-chloronitrobenzene is mostly liquid and has a special odor. However, this smell is not pleasant, it is really irritating, and it may cause discomfort if smelled.
Times and boiling point and melting point. The boiling point is related to the temperature at which it changes from liquid to gaseous state. The boiling point of 2-fluoro-3-chloronitrobenzene is quite high, due to the intermolecular forces. There is a van der Waals force between molecules, which requires more energy to overcome this force, so as to realize the phase transition. As for the melting point, it also depends on the molecular structure and interaction. Under a specific temperature, this substance can be converted from solid to liquid.
Furthermore, solubility is also an important physical property. In water, the solubility of 2-fluoro-3-chloronitrobenzene is very small. Because its molecular polarity is quite different from that of water, water is a strongly polar molecule, while the polarity of 2-fluoro-3-chloronitrobenzene is relatively weak. According to the principle of "similar miscibility", the two are difficult to dissolve. However, in organic solvents, such as ethanol, ether, etc., its solubility is better. The molecular polarity of organic solvents is similar to that of 2-fluoro-3-chloronitrobenzene, and weak interactions can be formed between molecules to promote its dissolution.
In addition, the density cannot be ignored. 2-fluoro-3-chloronitrobenzene has a higher density than water. If it is mixed with water, it can be seen to sink to the bottom after standing. This density characteristic is important in many chemical operations and separation processes.
In summary, the physical properties of 2-fluoro-3-chloronitrobenzene, such as state, odor, melting point, solubility, and density, are determined by its molecular structure and intermolecular interactions, and these properties need to be carefully considered when applied in chemical engineering, scientific research, and other fields.
What are 2-fluoro-3-chloronitrobenzene synthesis methods?
To make 2-fluoro-3-chloronitrobenzene, there are many ways to synthesize it. One of the common methods is to use o-chloronitrobenzene as the starting material. First, the o-chloronitrobenzene meets the fluorinating agent, such as anhydrous potassium fluoride. In a specific reaction vessel, add an appropriate amount of phase transfer catalyst, such as quaternary ammonium salt. Add high temperature and stirring to make it fully react. This step aims to replace the chlorine atom with the fluorine atom to obtain 2-fluoronitrobenzene.
Then, take out the 2-fluoronitrobenzene and place it in another reaction system. Introduce chlorinated reagents, such as chlorine gas or sulfoxide chloride, etc. Following the appropriate reaction conditions, either temperature control or pressure regulation, the chlorination reaction occurs. After this step, chlorine atoms are introduced at specific positions in the benzene ring to obtain 2-fluoro-3-chloronitrobenzene.
Another way is to start with m-chloroaniline. Shilling m-chloroaniline undergoes a diazotization reaction, and a solution of sodium nitrite and inorganic acid interacts with it to form a diazosalt. Then, the diazosalt reacts with fluoroboronic acid or its salts to form a diazosalt of fluoroboronic acid. This salt is decomposed by heat or other treatments to obtain m-chlorofluorobenzene.
m-chlorofluorobenzene is then nitrified, and a mixed acid (a mixture of nitric acid and sulfuric acid) is used as a nitrifying agent. 2-Fluoro-3-chloronitrobenzene can also be obtained by controlling the reaction temperature, time and other conditions so that the nitro group is introduced into the specific position of m-chlorofluorobenzene. The synthesis process has its own advantages and disadvantages. According to the actual situation, such as the availability of raw materials, cost considerations, product purity requirements, etc., choose the good one and use it.
Then, take out the 2-fluoronitrobenzene and place it in another reaction system. Introduce chlorinated reagents, such as chlorine gas or sulfoxide chloride, etc. Following the appropriate reaction conditions, either temperature control or pressure regulation, the chlorination reaction occurs. After this step, chlorine atoms are introduced at specific positions in the benzene ring to obtain 2-fluoro-3-chloronitrobenzene.
Another way is to start with m-chloroaniline. Shilling m-chloroaniline undergoes a diazotization reaction, and a solution of sodium nitrite and inorganic acid interacts with it to form a diazosalt. Then, the diazosalt reacts with fluoroboronic acid or its salts to form a diazosalt of fluoroboronic acid. This salt is decomposed by heat or other treatments to obtain m-chlorofluorobenzene.
m-chlorofluorobenzene is then nitrified, and a mixed acid (a mixture of nitric acid and sulfuric acid) is used as a nitrifying agent. 2-Fluoro-3-chloronitrobenzene can also be obtained by controlling the reaction temperature, time and other conditions so that the nitro group is introduced into the specific position of m-chlorofluorobenzene. The synthesis process has its own advantages and disadvantages. According to the actual situation, such as the availability of raw materials, cost considerations, product purity requirements, etc., choose the good one and use it.
2-fluoro-3-chloronitrobenzene What are the precautions during storage and transportation?
2-Fluoro-3-chloronitrobenzene is an organic compound. When storing and transporting, many key matters need to be paid attention to.
When storing, the first environmental conditions. A cool and ventilated warehouse should be selected, away from fire and heat sources. Because of its flammability, it can cause combustion and explosion in case of open flames and hot topics, so the temperature of the warehouse should be controlled within a suitable range, usually not exceeding 30 ° C. Furthermore, it should be stored separately from oxidizing agents, reducing agents, and alkalis, and must not be mixed. This compound is chemically active and in contact with the above substances, it is easy to cause chemical reactions or cause dangerous situations. And the warehouse needs to be equipped with suitable materials for containing leaks to prevent accidental leakage.
During transportation, it is necessary to ensure that the packaging is complete and safely loaded. The packaging should meet relevant standards to effectively prevent leakage and damage. Transportation vehicles must also meet safety requirements and be equipped with corresponding fire equipment. During driving, drivers should drive slowly and avoid sudden braking and sharp turns to prevent damage to the packaging. At the same time, during transportation, they should follow the specified route and do not stop in densely populated areas and traffic arteries. If a leak occurs during transportation, the surrounding personnel should be quickly evacuated to the safe area, and irrelevant personnel should be strictly prohibited from approaching the contaminated area. Emergency responders should wear gas masks and protective clothing, and take corresponding measures to clean up the leakage. In this way, the storage and transportation of 2-fluoro-3-chloronitrobenzene are guaranteed.
When storing, the first environmental conditions. A cool and ventilated warehouse should be selected, away from fire and heat sources. Because of its flammability, it can cause combustion and explosion in case of open flames and hot topics, so the temperature of the warehouse should be controlled within a suitable range, usually not exceeding 30 ° C. Furthermore, it should be stored separately from oxidizing agents, reducing agents, and alkalis, and must not be mixed. This compound is chemically active and in contact with the above substances, it is easy to cause chemical reactions or cause dangerous situations. And the warehouse needs to be equipped with suitable materials for containing leaks to prevent accidental leakage.
During transportation, it is necessary to ensure that the packaging is complete and safely loaded. The packaging should meet relevant standards to effectively prevent leakage and damage. Transportation vehicles must also meet safety requirements and be equipped with corresponding fire equipment. During driving, drivers should drive slowly and avoid sudden braking and sharp turns to prevent damage to the packaging. At the same time, during transportation, they should follow the specified route and do not stop in densely populated areas and traffic arteries. If a leak occurs during transportation, the surrounding personnel should be quickly evacuated to the safe area, and irrelevant personnel should be strictly prohibited from approaching the contaminated area. Emergency responders should wear gas masks and protective clothing, and take corresponding measures to clean up the leakage. In this way, the storage and transportation of 2-fluoro-3-chloronitrobenzene are guaranteed.
2-fluoro-3-chloronitrobenzene impact on the environment and human health
2-Fluoro-3-chloronitrobenzene is an organic compound that has an impact on both the environment and human health.
In terms of the environment, once this substance is released into the natural environment, it is difficult to be degraded and can be retained for a long time. It may migrate with the flow of water, polluting rivers, lakes and seas and other water bodies, and aquatic organisms bear the brunt. If aquatic organisms mistakenly consume water containing this substance or eat food containing this pollutant, it can cause physiological disorders and even endanger life. And it can be transmitted and enriched through the food chain, which can harm higher organisms. It can also affect soil quality in the soil, hinder the absorption of nutrients by plant roots, cause poor plant growth, and affect the balance of the ecosystem.
As for human health, 2-fluoro-3-chloronitrobenzene is toxic. If inhaled through the respiratory tract, it can irritate the mucosa of the respiratory tract, cause cough, asthma and other discomfort, and long-term inhalation or damage lung function. If exposed through skin, it can penetrate the skin barrier, causing skin allergies, redness, swelling, itching and other symptoms, and in severe cases, it may cause skin ulceration. If eaten accidentally, it will damage the digestive system, cause nausea, vomiting, abdominal pain, etc., and may also involve important organs such as the liver and kidneys, affecting their normal function. Long-term exposure may even cause mutation and cancer.
Therefore, when producing and using this substance, when strictly following safety procedures, do a good job of protection and waste disposal, and must not let it wantonly endanger the environment and human health.
In terms of the environment, once this substance is released into the natural environment, it is difficult to be degraded and can be retained for a long time. It may migrate with the flow of water, polluting rivers, lakes and seas and other water bodies, and aquatic organisms bear the brunt. If aquatic organisms mistakenly consume water containing this substance or eat food containing this pollutant, it can cause physiological disorders and even endanger life. And it can be transmitted and enriched through the food chain, which can harm higher organisms. It can also affect soil quality in the soil, hinder the absorption of nutrients by plant roots, cause poor plant growth, and affect the balance of the ecosystem.
As for human health, 2-fluoro-3-chloronitrobenzene is toxic. If inhaled through the respiratory tract, it can irritate the mucosa of the respiratory tract, cause cough, asthma and other discomfort, and long-term inhalation or damage lung function. If exposed through skin, it can penetrate the skin barrier, causing skin allergies, redness, swelling, itching and other symptoms, and in severe cases, it may cause skin ulceration. If eaten accidentally, it will damage the digestive system, cause nausea, vomiting, abdominal pain, etc., and may also involve important organs such as the liver and kidneys, affecting their normal function. Long-term exposure may even cause mutation and cancer.
Therefore, when producing and using this substance, when strictly following safety procedures, do a good job of protection and waste disposal, and must not let it wantonly endanger the environment and human health.
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