2-Nitro-4-(Trifluoromethyl)-Chlorobenzene

Linshang Chemical

Specifications

HS Code

107043

Chemical Formula C7H3ClF3NO2
Molar Mass 225.55 g/mol
Appearance Colorless to light yellow liquid
Boiling Point Approx. 205 - 207 °C
Density Approx. 1.55 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low vapor pressure at room temperature
Flash Point Approx. 87 °C

As an accredited 2-Nitro-4-(Trifluoromethyl)-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2 - nitro - 4 - (trifluoromethyl) - chlorobenzene packaged in a sealed glass bottle.
Storage 2 - nitro - 4 - (trifluoromethyl) chlorobenzene should be stored in a cool, dry, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly - sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and bases due to potential reactivity. Follow local safety regulations for proper storage.
Shipping 2 - nitro - 4 - (trifluoromethyl) - chlorobenzene is shipped in specialized, corrosion - resistant containers. Strict safety protocols are followed, ensuring proper labeling, secure packaging to prevent leakage during transit.
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2-Nitro-4-(Trifluoromethyl)-Chlorobenzene 2-Nitro-4-(Trifluoromethyl)-Chlorobenzene
General Information
Where to Buy 2-Nitro-4-(Trifluoromethyl)-Chlorobenzene in China?
As a trusted 2-Nitro-4-(Trifluoromethyl)-Chlorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Nitro-4-(Trifluoromethyl)-Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2-nitro-4- (trifluoromethyl) chlorobenzene?
2-Nitro-4- (trifluoromethyl) chlorobenzene is a key intermediate in the field of organic synthesis. It has a wide range of uses and can be used as the cornerstone for the creation of new antibacterial and antiviral drugs in the field of pharmaceutical synthesis. Due to the special structure of the compound, it can endow the drug with unique biological activity and pharmacological properties, helping it to act more effectively on pathogens, inhibit or kill them.
It is also indispensable in the creation of pesticides. It can be converted into high-efficiency, low-toxicity and environmentally friendly pesticides, fungicides and other pesticides through specific chemical reactions. Due to the fluorine atoms in its structure, it can enhance the stability, lipophilicity and biological activity of pesticides, making it play an important role in crop protection, which can not only effectively control pests and diseases, but also reduce the adverse impact on the environment.
In the field of materials science, 2-nitro-4- (trifluoromethyl) chlorobenzene can be used as a raw material for the synthesis of special polymer materials. By polymerization or other chemical modification means, it is introduced into the polymer chain, thereby endowing the material with unique properties such as excellent heat resistance, chemical corrosion resistance and electrical properties. Such materials have broad application prospects in high-end fields such as electronics, aerospace, etc., and can meet the strict requirements for special properties of materials in related fields.
To sum up, 2-nitro-4- (trifluoromethyl) chlorobenzene plays an important role in many fields such as medicine, pesticides and materials science, and is of great significance to promote the development of related industries.
What are the physical properties of 2-nitro-4- (trifluoromethyl) chlorobenzene
2-Nitro-4- (trifluoromethyl) chlorobenzene, also an organic compound. It has special physical properties, which is what you are talking about in detail today.
Looking at its appearance, under room temperature, it is often colorless to light yellow liquid, with a clear texture, like a clear spring. Under the shimmering light, its flickering luster can be seen, like the brilliance of pearls, and the brightness of glaze.
Smell it, its smell is special, and it has a pungent smell. If you inhale it carelessly, it can cause nasal and throat discomfort. This smell is its significant feature. If you smell it, you can distinguish it.
As for the boiling point, it is about a specific temperature range. This temperature converts the substance from a liquid state to a gaseous state. When the temperature gradually rises and reaches the boiling point, the bubbles on the liquid surface surge, like boiling soup, and then turn into curling steam. The characteristics of its boiling point are crucial in chemical operations such as separation and purification. According to this characteristic, distillation can be carried out to obtain pure substances.
Melting point is also one of its important physical properties. When the temperature drops to a certain critical point, the substance slowly solidifies from the liquid state and turns into a solid state, just like a frozen frame of time, and the flowing state turns to a static shape. The value of this melting point is also the basis for identifying the substance and other substances. The melting points of different substances are different, just like human fingerprints, unique.
In terms of solubility, it has a certain solubility in organic solvents, such as ethanol, ether, etc., and can blend with these solvents, just like water emulsion. However, in water, its solubility is very small, dripping into water, like oil floating on the water surface, it is distinct and difficult to blend. This difference in solubility is a key reference for selecting suitable solvents in chemical production and laboratory operations, and is related to the process of the reaction and the purity of the product.
The characteristics of density cannot be underestimated. Its density is heavier than water. If it is placed in the same container as water, it will sink to the bottom of the water, just like a stone falling to the bottom of the abyss, and it will be stable. The properties of this density have important applications in the separation and storage of mixtures.
In summary, the physical properties of 2-nitro-4- (trifluoromethyl) chlorobenzene are of great significance in the fields of chemical industry and scientific research, providing the basis for in-depth research and rational use of this substance by relevant workers.
What are the chemical synthesis methods of 2-nitro-4- (trifluoromethyl) chlorobenzene
The synthesis of 2-nitro-4- (trifluoromethyl) chlorobenzene follows a numerical method. One is to start with 4- (trifluoromethyl) chlorobenzene and obtain it by nitrification. In this case, in a suitable reaction vessel, put 4- (trifluoromethyl) chlorobenzene, and slowly add mixed acids, such as a mixture of nitric acid and sulfuric acid. For mixed acids, nitric acid can be a nitrifying agent, and sulfuric acid can promote the reaction and increase the activity of nitric acid. Control its temperature, do not make it too high, avoid side reactions, and keep the reaction direction selected. Usually at a low temperature, such as between 0 and 10 degrees Celsius, slowly add the mixed acid, add it, and keep warm and stir for a while to make the reaction complete. After completion, quench with water, after extraction, washing, drying, distillation and other steps, 2-nitro-4- (trifluoromethyl) chlorobenzene can be obtained.
Second, with 2-nitro-4- (trifluoromethyl) aniline as a group, obtained by diazotization and Sandmeyer reaction. Take 2-nitro-4- (trifluoromethyl) aniline first, dissolve it in an appropriate amount of acid, such as hydrochloric acid, cool it to 0 to 5 degrees Celsius, add sodium nitrite solution dropwise to form diazonium salts. Diazonium salts are active. Then, add the hydrochloric acid solution of cuprous chloride, or the mixture of copper powder and hydrochloric acid. After the Sandmeyer reaction, the diazo group is replaced by chlorine to obtain the target product. After the reaction is completed, the pure 2-nitro-4 - (trifluoromethyl) chlorobenzene is obtained through extraction, separation and purification.
Or there are other methods, but the two are more commonly used. The methods of synthesis have their own advantages and disadvantages, and they need to be selected according to factors such as the ease of raw materials, the level of cost, and the purity of the product.
What are the precautions for 2-nitro-4- (trifluoromethyl) chlorobenzene during storage and transportation?
2-Nitro-4- (trifluoromethyl) chlorobenzene is an important compound in organic chemistry. When storing and transporting, many matters must be taken with care.
First words Storage, this compound is dangerous and should be placed in a cool, dry and well ventilated place. Avoid heat, fire and strong oxidizing agents to prevent unexpected reactions. Because of its flammable nature, in case of hot topics, open flames or strong oxidizing agents, or risk of combustion or even explosion. Therefore, in the place of storage, fireproof and explosion-proof devices are indispensable, such as fire extinguishers, automatic fire extinguishing systems, etc., to prepare for emergencies.
Furthermore, this compound may be harmful to the environment, and the storage place should have measures to prevent leakage. If there is a leak, it must be able to detect and deal with it in time to avoid pollution and the surrounding environment. It must also be stored separately from other chemicals to avoid interaction and accidents.
As for transportation, the transporter must be familiar with its nature and hazards, and have corresponding qualifications. The transportation equipment must be specially designed and treated to ensure the safety of this compound. Anti-vibration, impact and friction on the way, so that the compound may react.
When transporting, it is also necessary to comply with relevant regulations and standards to ensure compliance during transportation. The amount of transportation should also be strictly controlled, not too much transportation, to reduce the potential danger. Shipping documents must contain detailed information on the compound, such as name, nature, hazard and emergency response methods, so that the situation on the way can be responded to quickly.
All of these, in the storage and transportation of 2-nitro-4- (trifluoromethyl) chlorobenzene, are critical, slightly careless, or cause serious consequences, so we must abide by the rules to ensure safety.
What are the effects of 2-nitro-4- (trifluoromethyl) chlorobenzene on the environment and human health?
2-Nitro-4- (trifluoromethyl) chlorobenzene is also an organic compound. The impact on the environment and human health cannot be ignored.
First talk about its impact on the environment. If this substance is released in nature, it will disturb water, soil and atmosphere. In water bodies, it may cause harm to aquatic organisms. Its chemical properties may hinder the photosynthesis of aquatic plants, cause growth inhibition, and spread in the food chain, affect aquatic animals such as fish, or cause abnormal reproduction and development. In soil, it can change soil chemical properties, inhibit soil microbial activity, hinder nutrient circulation and decomposition of organic matter, damage soil fertility, and be unfavorable to vegetation growth. In the atmosphere, it enters the atmosphere through volatilization, etc., or participates in photochemical reactions to generate harmful secondary pollutants, such as ozone, which deteriorates the quality of the atmosphere.
As for the impact on human health, it should not be underestimated. It can be harmful through respiratory tract, skin contact or accidental ingestion. Respiratory inhalation, or irritation of respiratory mucosa, causing cough, asthma, breathing difficulties and other diseases. Long-term exposure may damage lung function and increase the risk of respiratory diseases. Skin contact may cause skin allergies, redness, swelling, itching. If eaten by mistake, it can damage the digestive system, cause nausea, vomiting, abdominal pain, etc. What's more, this substance may be potentially carcinogenic, teratogenic and mutagenic. Long-term exposure can damage human genetic material and affect the health of future generations. Therefore, in the production, use and disposal of 2-nitro-4- (trifluoromethyl) chlorobenzene, care should be taken to prevent its escape into the environment and reduce the harm to the environment and human health.