Linshang Chemical
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3,4,5-Trichlorobromobenzene
Linshang Chemical
|
HS Code |
266799 |
| Chemical Formula | C6H2BrCl3 |
| Molar Mass | 271.34 g/mol |
| Appearance | Solid (usually white to off - white) |
| Density | Data needed |
| Melting Point | Data needed |
| Boiling Point | Data needed |
| Solubility In Water | Low solubility in water |
| Solubility In Organic Solvents | Soluble in many organic solvents like benzene, toluene |
| Vapor Pressure | Data needed |
| Flash Point | Data needed |
| Odor | Data needed |
| Stability | Stable under normal conditions, but can react with strong oxidizing agents |
As an accredited 3,4,5-Trichlorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottles containing 3,4,5 - trichlorobromobenzene with tight - sealed packaging. |
| Storage | 3,4,5 - trichlorobromobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and other reactive substances to avoid potential chemical reactions. |
| Shipping | 3,4,5 - Trichlorobromobenzene is a chemical that requires careful shipping. It should be packaged in suitable containers to prevent leakage. Shipment must comply with hazardous material regulations, ensuring safe transportation. |
Competitive 3,4,5-Trichlorobromobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 3,4,5-Trichlorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 3,4,5-trichlorobromobenzene?
3,4,5-Trifluorobromobenzene is also an organic compound. Its chemical properties are unique, related to many chemical reactions and uses, and it is an important object of chemical research.
This compound has the typical properties of halogenated aromatics. The presence of bromine atoms and fluorine atoms gives it active chemical activity. Bromine is relatively easy to leave and can participate in nucleophilic substitution reactions. In case of nucleophilic reagents, bromine ions can be replaced to form new compounds. For example, in reaction with sodium alcohol, bromine atoms can be replaced by alkoxy groups to obtain corresponding ether compounds. This reaction mechanism is that nucleophilic reagents attack carbon atoms connected to bromine atoms, and bromine ions leave to form new carbon-oxygen bonds.
Furthermore, the electronegativity of fluorine atoms is strong, which has a great impact on the distribution of molecular electron clouds. Due to the electron-absorbing effect, the electron cloud density of benzene ring decreases, which decreases the electrophilic substitution activity of benzene ring. However, under certain conditions, electrophilic substitution can still occur, but the reaction conditions are more severe than benzene. For example, when nitrification occurs, stronger nitrifying reagents and stricter reaction conditions are required.
3,4,5-trifluorobromobenzene also exhibits good stability. Due to the high carbon-fluorine bond energy, the compound is not easy to decompose in general environment and can be stored for a long time. And its physical properties, such as boiling point, melting point, etc., are affected by halogen atoms and have significant changes compared with benzene. This property is of great significance in separation, purification and application. In the field of organic synthesis, it is often used as a key intermediate. After a series of reactions, complex organic compounds can be constructed, providing an important foundation for the development of pharmaceutical chemistry, materials science and many other fields.
This compound has the typical properties of halogenated aromatics. The presence of bromine atoms and fluorine atoms gives it active chemical activity. Bromine is relatively easy to leave and can participate in nucleophilic substitution reactions. In case of nucleophilic reagents, bromine ions can be replaced to form new compounds. For example, in reaction with sodium alcohol, bromine atoms can be replaced by alkoxy groups to obtain corresponding ether compounds. This reaction mechanism is that nucleophilic reagents attack carbon atoms connected to bromine atoms, and bromine ions leave to form new carbon-oxygen bonds.
Furthermore, the electronegativity of fluorine atoms is strong, which has a great impact on the distribution of molecular electron clouds. Due to the electron-absorbing effect, the electron cloud density of benzene ring decreases, which decreases the electrophilic substitution activity of benzene ring. However, under certain conditions, electrophilic substitution can still occur, but the reaction conditions are more severe than benzene. For example, when nitrification occurs, stronger nitrifying reagents and stricter reaction conditions are required.
3,4,5-trifluorobromobenzene also exhibits good stability. Due to the high carbon-fluorine bond energy, the compound is not easy to decompose in general environment and can be stored for a long time. And its physical properties, such as boiling point, melting point, etc., are affected by halogen atoms and have significant changes compared with benzene. This property is of great significance in separation, purification and application. In the field of organic synthesis, it is often used as a key intermediate. After a series of reactions, complex organic compounds can be constructed, providing an important foundation for the development of pharmaceutical chemistry, materials science and many other fields.
What are the physical properties of 3,4,5-trichlorobromobenzene?
3,4,5-trifluorobromobenzene is also an organic compound. It has various physical properties and is related to its experiment and application.
First of all, its phase state and color. At room temperature and pressure, 3,4,5-trifluorobromobenzene is a colorless to light yellow liquid. This color sign is quite useful for visually distinguishing this substance. If you see a colorless to light yellow liquid and know that it is in a related chemical system, you need to suspect it or this substance.
Times and boiling point. The boiling point of 3,4,5-trifluorobrobenzene is about 142 ° C - 144 ° C. The boiling point is the critical temperature at which the substance changes from liquid to gas. At this temperature, the molecule obtains enough energy to break free from the liquid phase and escape into the gas phase. This boiling point value is a key parameter when separating and purifying this substance. For example, the method of distillation, which controls the temperature near the boiling point, can make 3,4,5-trifluorobromobenzene vaporized and separated from the mixture, and then condensed and collected into a liquid state to achieve the purpose of purification.
Let's talk about the density. Its density is about 1.738g/mL. The density is the mass of the substance per unit volume. In the experimental operation, the density is known, and the corresponding volume can be accurately measured according to the required mass, or the mass can be estimated according to the volume. It is indispensable data for configuring the solution and participating in the reaction.
and solubility. 3,4,5-trifluorobromobenzene is insoluble in water, but soluble in common organic solvents such as ethanol, ether, acetone, etc. This solubility characteristic is of great significance in organic synthesis, extraction and other processes. For example, during extraction, because it is insoluble in water but soluble in organic solvents, this property can be used to extract it from the aqueous phase with a suitable organic solvent to achieve separation and enrichment.
In addition, 3,4,5-trifluorobromobenzene still has a certain degree of volatility, and in the open system, it will gradually evaporate and dissipate. And because it contains halogen atoms, its chemical properties are also related to halogen atoms, and it can participate in many chemical reactions under specific conditions. Although this is not a physical property category, it is related to physical properties, which together affect its performance in practical applications.
First of all, its phase state and color. At room temperature and pressure, 3,4,5-trifluorobromobenzene is a colorless to light yellow liquid. This color sign is quite useful for visually distinguishing this substance. If you see a colorless to light yellow liquid and know that it is in a related chemical system, you need to suspect it or this substance.
Times and boiling point. The boiling point of 3,4,5-trifluorobrobenzene is about 142 ° C - 144 ° C. The boiling point is the critical temperature at which the substance changes from liquid to gas. At this temperature, the molecule obtains enough energy to break free from the liquid phase and escape into the gas phase. This boiling point value is a key parameter when separating and purifying this substance. For example, the method of distillation, which controls the temperature near the boiling point, can make 3,4,5-trifluorobromobenzene vaporized and separated from the mixture, and then condensed and collected into a liquid state to achieve the purpose of purification.
Let's talk about the density. Its density is about 1.738g/mL. The density is the mass of the substance per unit volume. In the experimental operation, the density is known, and the corresponding volume can be accurately measured according to the required mass, or the mass can be estimated according to the volume. It is indispensable data for configuring the solution and participating in the reaction.
and solubility. 3,4,5-trifluorobromobenzene is insoluble in water, but soluble in common organic solvents such as ethanol, ether, acetone, etc. This solubility characteristic is of great significance in organic synthesis, extraction and other processes. For example, during extraction, because it is insoluble in water but soluble in organic solvents, this property can be used to extract it from the aqueous phase with a suitable organic solvent to achieve separation and enrichment.
In addition, 3,4,5-trifluorobromobenzene still has a certain degree of volatility, and in the open system, it will gradually evaporate and dissipate. And because it contains halogen atoms, its chemical properties are also related to halogen atoms, and it can participate in many chemical reactions under specific conditions. Although this is not a physical property category, it is related to physical properties, which together affect its performance in practical applications.
What are the main uses of 3,4,5-trichlorobromobenzene?
3,4,5-trifluorobromobenzene is also an important agent in organic synthesis. It has a wide range of uses and has extraordinary performance in the fields of medicine, pesticides and materials.
In the field of medicine, it can be a key intermediate for the creation of new drugs. Because of its fluorine atom, it can change the physical, chemical and biological properties of compounds, such as improving fat solubility, making it easier for drugs to penetrate biofilms and enhance their bioavailability; and the introduction of fluorine atoms can increase the stability of molecules, slow down the metabolism of drugs, and make the drug effect last longer. Taking the research and development of antidepressants as an example, fluorinated compounds often have unique physiological activities. 3,4,5-trifluorobromobenzene may provide a unique structural basis for the synthesis of such drugs, which will help to develop more effective and less side effects.
In pesticides, this compound is also very useful. Fluorine atoms give pesticides higher activity and selectivity, can accurately act on target organisms, and have good environmental compatibility. For example, new insecticides can be synthesized based on 3,4,5-trifluorobromobenzene, which is highly toxic to pests and less harmful to non-target organisms. It not only ensures a good harvest of crops, but also protects the balance of the ecological environment.
In the field of materials science, 3,4,5-trifluorobromobenzene can be used as a raw material for the synthesis of high-performance polymer materials. The resulting polymers may have excellent thermal stability, chemical stability and electrical properties. For example, in electronic materials, such fluoropolymers can be used to make high-performance insulating materials, photoresists, etc., to meet the high-performance requirements of electronic equipment and promote the progress of electronic technology.
In short, 3,4,5-trifluorobromobenzene, with its unique structure and properties, is an indispensable and important substance in many fields, injecting vitality into the development of various industries and promoting its continuous innovation and progress.
In the field of medicine, it can be a key intermediate for the creation of new drugs. Because of its fluorine atom, it can change the physical, chemical and biological properties of compounds, such as improving fat solubility, making it easier for drugs to penetrate biofilms and enhance their bioavailability; and the introduction of fluorine atoms can increase the stability of molecules, slow down the metabolism of drugs, and make the drug effect last longer. Taking the research and development of antidepressants as an example, fluorinated compounds often have unique physiological activities. 3,4,5-trifluorobromobenzene may provide a unique structural basis for the synthesis of such drugs, which will help to develop more effective and less side effects.
In pesticides, this compound is also very useful. Fluorine atoms give pesticides higher activity and selectivity, can accurately act on target organisms, and have good environmental compatibility. For example, new insecticides can be synthesized based on 3,4,5-trifluorobromobenzene, which is highly toxic to pests and less harmful to non-target organisms. It not only ensures a good harvest of crops, but also protects the balance of the ecological environment.
In the field of materials science, 3,4,5-trifluorobromobenzene can be used as a raw material for the synthesis of high-performance polymer materials. The resulting polymers may have excellent thermal stability, chemical stability and electrical properties. For example, in electronic materials, such fluoropolymers can be used to make high-performance insulating materials, photoresists, etc., to meet the high-performance requirements of electronic equipment and promote the progress of electronic technology.
In short, 3,4,5-trifluorobromobenzene, with its unique structure and properties, is an indispensable and important substance in many fields, injecting vitality into the development of various industries and promoting its continuous innovation and progress.
What are the synthesis methods of 3,4,5-trichlorobromobenzene?
The synthesis methods of 3,4,5-trifluorobromobenzene are many different, and each method has its own strengths and shortcomings. Today, the number of methods is described in detail below.
One is the halogen exchange method. This is a fluorine-containing compound and bromoaromatic hydrocarbons as raw materials. Under specific reaction conditions, halogen atoms are exchanged with each other to obtain 3,4,5-trifluorobromobenzene. The raw materials are easy to find, and the reaction steps are relatively clear. However, the reaction conditions are harsh, specific catalysts and suitable temperatures and pressures are required, and there are many side reactions, so the purity and yield of the product are easily affected.
The second is the direct fluorination method. It is a method of synthesizing the target product by directly introducing fluorine atoms with bromobenzene as the starting material. This method is theoretically simple and can be done in one step. However, the actual operation is not easy. Fluorine is active, highly oxidizing and corrosive, and requires extremely high safety for reaction equipment. The selectivity of the reaction is also poor, and it is easy to generate a variety of by-products. Separation and purification are quite difficult.
The third is a multi-step synthesis method. Usually, a specific substitution reaction is carried out on the benzene ring, some functional groups are introduced, and then a series of transformations are carried out to gradually introduce fluorine atoms and bromine atoms. Although there are many steps in this way, the reaction conditions at each step are relatively mild, easy to control, and the requirements for reaction equipment are not as strict as those of the direct fluorination method. By rationally designing the reaction route, the purity and yield of the product can be effectively improved. However, the multi-step reaction results in a long process flow and an increase in cost.
All methods for synthesizing 3,4,5-trifluorobromobenzene have their own advantages and disadvantages. In practical application, the appropriate synthesis method should be carefully selected according to the availability of raw materials, equipment conditions, cost considerations, and requirements for product purity and yield.
One is the halogen exchange method. This is a fluorine-containing compound and bromoaromatic hydrocarbons as raw materials. Under specific reaction conditions, halogen atoms are exchanged with each other to obtain 3,4,5-trifluorobromobenzene. The raw materials are easy to find, and the reaction steps are relatively clear. However, the reaction conditions are harsh, specific catalysts and suitable temperatures and pressures are required, and there are many side reactions, so the purity and yield of the product are easily affected.
The second is the direct fluorination method. It is a method of synthesizing the target product by directly introducing fluorine atoms with bromobenzene as the starting material. This method is theoretically simple and can be done in one step. However, the actual operation is not easy. Fluorine is active, highly oxidizing and corrosive, and requires extremely high safety for reaction equipment. The selectivity of the reaction is also poor, and it is easy to generate a variety of by-products. Separation and purification are quite difficult.
The third is a multi-step synthesis method. Usually, a specific substitution reaction is carried out on the benzene ring, some functional groups are introduced, and then a series of transformations are carried out to gradually introduce fluorine atoms and bromine atoms. Although there are many steps in this way, the reaction conditions at each step are relatively mild, easy to control, and the requirements for reaction equipment are not as strict as those of the direct fluorination method. By rationally designing the reaction route, the purity and yield of the product can be effectively improved. However, the multi-step reaction results in a long process flow and an increase in cost.
All methods for synthesizing 3,4,5-trifluorobromobenzene have their own advantages and disadvantages. In practical application, the appropriate synthesis method should be carefully selected according to the availability of raw materials, equipment conditions, cost considerations, and requirements for product purity and yield.
What are the precautions for 3,4,5-trichlorobromobenzene during storage and transportation?
3,4,5-trifluorobromobenzene is a key raw material in organic synthesis. During storage and transportation, many matters must be paid attention to:
First, when storing, it should be placed in a cool and well-ventilated place. This is because 3,4,5-trifluorobromobenzene is more sensitive to heat, and high temperature can easily cause chemical reactions such as decomposition, which can damage the quality. If the storage environment temperature is too high, it may cause material deterioration and affect the subsequent use effect.
Second, be sure to ensure that the storage container is well sealed. The substance is volatile. If the container is not well sealed, it will evaporate into the air, which will not only cause material loss, but also because of its certain toxicity, volatilize in the air or cause harm to the surrounding environment and human health.
Third, it should be stored separately from oxidants, acids, etc., and must not be mixed. 3,4,5-trifluorobromobenzene is chemically active. Contact with oxidants, acids, etc., is very likely to trigger violent chemical reactions, and even cause serious accidents such as combustion and explosion, endangering life and property safety.
Fourth, during transportation, it is necessary to strictly abide by the relevant dangerous chemical transportation regulations. The vehicle must have reliable anti-leakage, fire prevention, explosion-proof and other safety facilities. In the event of a leak, 3,4,5-trifluorobromobenzene will flow into the environment, causing pollution to soil, water sources, etc., and the leaked substances will evaporate in the air, which will also have adverse effects on the atmospheric environment. At the same time, transportation personnel must undergo professional training and be familiar with the characteristics of the chemical and emergency treatment methods, so that they can respond quickly and effectively in case of emergencies and reduce hazards.
First, when storing, it should be placed in a cool and well-ventilated place. This is because 3,4,5-trifluorobromobenzene is more sensitive to heat, and high temperature can easily cause chemical reactions such as decomposition, which can damage the quality. If the storage environment temperature is too high, it may cause material deterioration and affect the subsequent use effect.
Second, be sure to ensure that the storage container is well sealed. The substance is volatile. If the container is not well sealed, it will evaporate into the air, which will not only cause material loss, but also because of its certain toxicity, volatilize in the air or cause harm to the surrounding environment and human health.
Third, it should be stored separately from oxidants, acids, etc., and must not be mixed. 3,4,5-trifluorobromobenzene is chemically active. Contact with oxidants, acids, etc., is very likely to trigger violent chemical reactions, and even cause serious accidents such as combustion and explosion, endangering life and property safety.
Fourth, during transportation, it is necessary to strictly abide by the relevant dangerous chemical transportation regulations. The vehicle must have reliable anti-leakage, fire prevention, explosion-proof and other safety facilities. In the event of a leak, 3,4,5-trifluorobromobenzene will flow into the environment, causing pollution to soil, water sources, etc., and the leaked substances will evaporate in the air, which will also have adverse effects on the atmospheric environment. At the same time, transportation personnel must undergo professional training and be familiar with the characteristics of the chemical and emergency treatment methods, so that they can respond quickly and effectively in case of emergencies and reduce hazards.
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