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3,4-Dichloro-4-Nitrobenzene
Linshang Chemical
|
HS Code |
660682 |
| Chemical Formula | C6H3Cl2NO2 |
| Molar Mass | 192.00 g/mol |
| Appearance | Yellow - white solid |
| Odor | Pungent |
| Melting Point | 99 - 101 °C |
| Boiling Point | 284 - 286 °C |
| Density | 1.62 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like benzene, toluene |
| Vapor Pressure | Low vapor pressure |
As an accredited 3,4-Dichloro-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 3,4 - dichloro - 4 - nitrobenzene packaged in a sealed plastic bottle. |
| Storage | 3,4 - dichloro - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly closed container to prevent vapor release. Separate it from incompatible substances, like reducing agents. Adhere to safety regulations to ensure safe storage. |
| Shipping | 3,4 - dichloro - 4 - nitrobenzene is a chemical. Shipping should be in accordance with hazardous material regulations. It must be properly packaged, labeled, and transported by carriers approved for such chemicals to ensure safety. |
Competitive 3,4-Dichloro-4-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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What are the main uses of 3,4-dichloro-4-nitrobenzene?
The main uses of 3,4-dioxy-4-aminoquinoline are as follows:
This compound has important applications in the field of medicine. During the development of antimalarial drugs, its structural analogs have exhibited unique antimalarial activities. Many studies have focused on the use of 3,4-dioxy-4-aminoquinoline as the base skeleton, and through modification and modification of its chemical structure, it is hoped to find more efficient and low-toxicity antimalarial drugs. The core lies in the fact that the structure can precisely act on the specific metabolic links or biological targets of the malaria parasite, interfering with the normal growth and reproduction process of the malaria parasite, so as to achieve the effect of anti-malaria.
At the same time, in the field of organic synthesis, 3,4-dioxo-4-aminoquinoline can be used as the current or intermediate. With its special molecular structure and reactivity, a series of organic compounds with complex structures and special properties can be prepared by various organic chemical reactions, such as nucleophilic substitution, electrophilic substitution, cyclization reaction, etc. These compounds may have potential application value in many fields such as materials science, medicinal chemistry, and total synthesis of natural products.
In addition, due to their specific electron cloud distribution and conjugation system, 3,4-dioxo-4-aminoquinoline and its derivatives may exhibit unique optical properties in some photophysical and photochemical studies, such as fluorescence emission characteristics. This makes them have certain research and development potential in the fields of fluorescent probes, optoelectronic devices, etc., and is expected to be used to detect specific substances or construct new optoelectronic devices.
This compound has important applications in the field of medicine. During the development of antimalarial drugs, its structural analogs have exhibited unique antimalarial activities. Many studies have focused on the use of 3,4-dioxy-4-aminoquinoline as the base skeleton, and through modification and modification of its chemical structure, it is hoped to find more efficient and low-toxicity antimalarial drugs. The core lies in the fact that the structure can precisely act on the specific metabolic links or biological targets of the malaria parasite, interfering with the normal growth and reproduction process of the malaria parasite, so as to achieve the effect of anti-malaria.
At the same time, in the field of organic synthesis, 3,4-dioxo-4-aminoquinoline can be used as the current or intermediate. With its special molecular structure and reactivity, a series of organic compounds with complex structures and special properties can be prepared by various organic chemical reactions, such as nucleophilic substitution, electrophilic substitution, cyclization reaction, etc. These compounds may have potential application value in many fields such as materials science, medicinal chemistry, and total synthesis of natural products.
In addition, due to their specific electron cloud distribution and conjugation system, 3,4-dioxo-4-aminoquinoline and its derivatives may exhibit unique optical properties in some photophysical and photochemical studies, such as fluorescence emission characteristics. This makes them have certain research and development potential in the fields of fluorescent probes, optoelectronic devices, etc., and is expected to be used to detect specific substances or construct new optoelectronic devices.
What are the physical properties of 3,4-dichloro-4-nitrobenzene
3,4-Dioxide-4-aminoquinoline, this material property is special, let me list it in detail.
Its shape is often solid, and its color may be light yellow to brown. The point of melting and boiling is related to the change of the state of matter. The melting point is about a certain degree, which is the boundary of solid-state liquid conversion; the boiling point also has a number, which is a sign of liquid-to-gas transformation. However, the specific value varies slightly depending on the difference between the measurement method and the pure substance.
Solubility is also an important feature. In water, its solubility is limited, and the gravitational attraction between the water molecules is insufficient due to its molecular structure. However, in organic solvents, such as alcohols and ethers, their solubility may be different. Alcohol polarity, with 3,4-dioxide-4-aminoquinoline or have a suitable effect, so it is slightly soluble; ethers, although slightly weaker polarity, may also be partially soluble.
Furthermore, its chemical activity should not be underestimated. Amino is an active group, basic, and can form salts with acids. In chemical reactions, it is easy to interact with electrophilic reagents, substitution and other reactions occur. The structure of dioxide also affects the distribution of its electron cloud, making the reactivity of the molecule as a whole unique. In the field of organic synthesis, it is often an important raw material or intermediate. Based on it, it can form a variety of complex compounds and is used in medicine, materials and other industries.
Because of its structure containing nitrogen heterocycles, it has a certain conjugate system, so it has its own characteristic absorption in spectroscopy. For example, in the infrared spectrum, specific functional groups have corresponding absorption peaks, according to which their structures can be identified; in the ultraviolet spectrum, there are also absorption peaks due to conjugation, which help in qualitative and quantitative analysis. These are all important in their physical properties, and are key to research and application.
Its shape is often solid, and its color may be light yellow to brown. The point of melting and boiling is related to the change of the state of matter. The melting point is about a certain degree, which is the boundary of solid-state liquid conversion; the boiling point also has a number, which is a sign of liquid-to-gas transformation. However, the specific value varies slightly depending on the difference between the measurement method and the pure substance.
Solubility is also an important feature. In water, its solubility is limited, and the gravitational attraction between the water molecules is insufficient due to its molecular structure. However, in organic solvents, such as alcohols and ethers, their solubility may be different. Alcohol polarity, with 3,4-dioxide-4-aminoquinoline or have a suitable effect, so it is slightly soluble; ethers, although slightly weaker polarity, may also be partially soluble.
Furthermore, its chemical activity should not be underestimated. Amino is an active group, basic, and can form salts with acids. In chemical reactions, it is easy to interact with electrophilic reagents, substitution and other reactions occur. The structure of dioxide also affects the distribution of its electron cloud, making the reactivity of the molecule as a whole unique. In the field of organic synthesis, it is often an important raw material or intermediate. Based on it, it can form a variety of complex compounds and is used in medicine, materials and other industries.
Because of its structure containing nitrogen heterocycles, it has a certain conjugate system, so it has its own characteristic absorption in spectroscopy. For example, in the infrared spectrum, specific functional groups have corresponding absorption peaks, according to which their structures can be identified; in the ultraviolet spectrum, there are also absorption peaks due to conjugation, which help in qualitative and quantitative analysis. These are all important in their physical properties, and are key to research and application.
What are the chemical properties of 3,4-dichloro-4-nitrobenzene?
3% 2C4-dioxy-4-cyanopyridine is an organic compound with unique chemical properties, which is worth studying in detail.
In this compound, the dioxy structure endows it with certain stability and special reactivity. Oxygen atoms have high electronegativity, which can cause uneven distribution of electron clouds in molecules and affect their chemical reaction tendency. In nucleophilic substitution reactions, this structure may promote the change of electron cloud density at the check point of the reaction, making nucleophiles more susceptible to attack.
Cyanyl, as a strong electron-absorbing group, greatly affects the distribution and polarity of molecular electron clouds. It reduces the electron cloud density of pyridine rings, enhances the positive electricity of carbon atoms on the rings, and is more susceptible to nucleophilic attack. The cyanyl group itself can participate in a variety of reactions, such as hydrolysis to form carboxyl groups, or addition reactions with compounds containing active hydrogen.
The pyridine ring is weakly basic because it contains nitrogen atoms. The lone pair electrons on the nitrogen atom can accept protons, so that the compound can be protonated under acidic conditions or change its physical and chemical properties. The electron cloud of the pyridine ring is not uniformly distributed, and the carbon atoms at different positions have different reactivity. Electrophilic substitution reactions can occur under specific conditions, and the substitution positions are affected by the electronic effects of substituents such as dioxy and cyanyl groups.
From the perspective of redox, the compound may participate in the redox reaction. Under the action of appropriate oxidants or reducing agents, some chemical bonds in its structure may be broken and recombined to achieve oxidation state changes.
In conclusion, 3% 2C4-dioxy-4-cyanopyridine has a unique structure and integrates a variety of chemical properties. It may have important applications in organic synthesis, medicinal chemistry and other fields, and can be used as a key intermediate to participate in the construction of many complex organic compounds.
In this compound, the dioxy structure endows it with certain stability and special reactivity. Oxygen atoms have high electronegativity, which can cause uneven distribution of electron clouds in molecules and affect their chemical reaction tendency. In nucleophilic substitution reactions, this structure may promote the change of electron cloud density at the check point of the reaction, making nucleophiles more susceptible to attack.
Cyanyl, as a strong electron-absorbing group, greatly affects the distribution and polarity of molecular electron clouds. It reduces the electron cloud density of pyridine rings, enhances the positive electricity of carbon atoms on the rings, and is more susceptible to nucleophilic attack. The cyanyl group itself can participate in a variety of reactions, such as hydrolysis to form carboxyl groups, or addition reactions with compounds containing active hydrogen.
The pyridine ring is weakly basic because it contains nitrogen atoms. The lone pair electrons on the nitrogen atom can accept protons, so that the compound can be protonated under acidic conditions or change its physical and chemical properties. The electron cloud of the pyridine ring is not uniformly distributed, and the carbon atoms at different positions have different reactivity. Electrophilic substitution reactions can occur under specific conditions, and the substitution positions are affected by the electronic effects of substituents such as dioxy and cyanyl groups.
From the perspective of redox, the compound may participate in the redox reaction. Under the action of appropriate oxidants or reducing agents, some chemical bonds in its structure may be broken and recombined to achieve oxidation state changes.
In conclusion, 3% 2C4-dioxy-4-cyanopyridine has a unique structure and integrates a variety of chemical properties. It may have important applications in organic synthesis, medicinal chemistry and other fields, and can be used as a key intermediate to participate in the construction of many complex organic compounds.
What is the production method of 3,4-dichloro-4-nitrobenzene?
3,4-Dioxy-4-cyanopyridine is an important compound in organic synthesis. The common preparation methods are as follows:
First, pyridine derivatives are used as starting materials and prepared through multi-step reactions. If a specific substituted pyridine is selected, its specific position is functionalized first. Halogen atoms can be introduced by halogenation reaction, and then nucleophilic substitution reaction occurs with cyanide-containing reagents to introduce cyano groups. Then another position is oxidized to build a dioxy structure. This process requires precise control of reaction conditions, such as reaction temperature, reaction time, proportion of reactants, and the catalyst used. For example, during halogenation reactions, different reaction temperatures can cause differences in the substitution positions of halogen atoms on the pyridine ring, which affects the structure of the final product.
Second, a cyclization reaction strategy is adopted. A chain compound with suitable functional groups is selected, and the pyridine ring is constructed through an intramolecular cyclization reaction, and the desired dioxy and cyano functional groups are introduced at the same time. For example, a chain precursor containing functional groups such as nitrogen, oxygen, and cyano is selected, and under suitable catalyst and reaction conditions, the cyclization reaction occurs in the molecule. The key to this method is to design a reasonable precursor structure to ensure that the cyclization reaction can occur efficiently and selectively.
Third, the reaction is catalyzed by transition metals. Transition metal catalysts can effectively promote the formation and cleavage of various chemical bonds, thereby facilitating the synthesis of 3,4-dioxy-4-cyanopyridine. For example, transition metal catalysts such as palladium and copper can be used to catalyze the reaction between halogenated pyridine derivatives and cyanide-containing reagents and oxygen-containing reagents to achieve the construction of target compounds. In this process, the type of transition metal catalyst and the choice of ligand have a significant impact on the reaction activity and selectivity.
When preparing 3,4-dioxy-4-cyanopyridine, it is necessary to carefully select the most suitable synthesis method according to the actual situation, considering many factors such as the availability of raw materials, the difficulty of controlling reaction conditions, cost and yield.
First, pyridine derivatives are used as starting materials and prepared through multi-step reactions. If a specific substituted pyridine is selected, its specific position is functionalized first. Halogen atoms can be introduced by halogenation reaction, and then nucleophilic substitution reaction occurs with cyanide-containing reagents to introduce cyano groups. Then another position is oxidized to build a dioxy structure. This process requires precise control of reaction conditions, such as reaction temperature, reaction time, proportion of reactants, and the catalyst used. For example, during halogenation reactions, different reaction temperatures can cause differences in the substitution positions of halogen atoms on the pyridine ring, which affects the structure of the final product.
Second, a cyclization reaction strategy is adopted. A chain compound with suitable functional groups is selected, and the pyridine ring is constructed through an intramolecular cyclization reaction, and the desired dioxy and cyano functional groups are introduced at the same time. For example, a chain precursor containing functional groups such as nitrogen, oxygen, and cyano is selected, and under suitable catalyst and reaction conditions, the cyclization reaction occurs in the molecule. The key to this method is to design a reasonable precursor structure to ensure that the cyclization reaction can occur efficiently and selectively.
Third, the reaction is catalyzed by transition metals. Transition metal catalysts can effectively promote the formation and cleavage of various chemical bonds, thereby facilitating the synthesis of 3,4-dioxy-4-cyanopyridine. For example, transition metal catalysts such as palladium and copper can be used to catalyze the reaction between halogenated pyridine derivatives and cyanide-containing reagents and oxygen-containing reagents to achieve the construction of target compounds. In this process, the type of transition metal catalyst and the choice of ligand have a significant impact on the reaction activity and selectivity.
When preparing 3,4-dioxy-4-cyanopyridine, it is necessary to carefully select the most suitable synthesis method according to the actual situation, considering many factors such as the availability of raw materials, the difficulty of controlling reaction conditions, cost and yield.
What are the effects of 3,4-dichloro-4-nitrobenzene on the environment and humans?
Although there is no direct explanation of the specific modern chemical substance "3,4-dioxy-4-cyanofuran has any impact on the environment and human body" in "Tiangong Kaiwu", the following can be discussed in order to understand the present from the ancient times.
All things are related to each other. If such chemical substances exist in nature, they will have an impact on the environment. The ancient cloud "When the water is clear, there will be no fish". It is said that subtle changes in the environment can cause biological changes. If this chemical substance enters the nature, it may affect the nature of water and soil. The land depends on the balance of nature. If it is disturbed by this, the fertility of the soil and the reproduction of microorganisms may change. Water is the source of life. When it enters the water body, it may cause harm to aquatic organisms, ranging from planktonic insects to the genus of fish and shrimp, or due to illness or death, causing an imbalance in the water ecology.
As for the human body, there was also a saying in ancient times that "disease enters through the mouth" and "qi passes through the nose". If people eat food and water containing this substance through the mouth, or breathe in the air containing it, it will be harmful. The organs and meridians of the human body perform their duties to achieve balance and health. This chemical may disturb the normal physiology of the human body, such as damaging the operation of qi and blood, hindering the function of the organs. Or cause meridian blockage, causing damage to the body's righteous qi, and evil qi is easy to invade, resulting in various diseases. In light cases, it is uncomfortable, and in severe cases, it may endanger life.
And looking at the mining industry in ancient times, the mineral poison overflowed, causing pollution of the surrounding water and soil, and the people were sick. Although the effects of this chemical substance are different in different times, there may be similar reasons for its harm to the environment and human body. Therefore, people today should be careful with such chemicals to prevent their harm to the environment and human body, so as to ensure the balance of all things and the health of the human body.
All things are related to each other. If such chemical substances exist in nature, they will have an impact on the environment. The ancient cloud "When the water is clear, there will be no fish". It is said that subtle changes in the environment can cause biological changes. If this chemical substance enters the nature, it may affect the nature of water and soil. The land depends on the balance of nature. If it is disturbed by this, the fertility of the soil and the reproduction of microorganisms may change. Water is the source of life. When it enters the water body, it may cause harm to aquatic organisms, ranging from planktonic insects to the genus of fish and shrimp, or due to illness or death, causing an imbalance in the water ecology.
As for the human body, there was also a saying in ancient times that "disease enters through the mouth" and "qi passes through the nose". If people eat food and water containing this substance through the mouth, or breathe in the air containing it, it will be harmful. The organs and meridians of the human body perform their duties to achieve balance and health. This chemical may disturb the normal physiology of the human body, such as damaging the operation of qi and blood, hindering the function of the organs. Or cause meridian blockage, causing damage to the body's righteous qi, and evil qi is easy to invade, resulting in various diseases. In light cases, it is uncomfortable, and in severe cases, it may endanger life.
And looking at the mining industry in ancient times, the mineral poison overflowed, causing pollution of the surrounding water and soil, and the people were sick. Although the effects of this chemical substance are different in different times, there may be similar reasons for its harm to the environment and human body. Therefore, people today should be careful with such chemicals to prevent their harm to the environment and human body, so as to ensure the balance of all things and the health of the human body.
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