Linshang Chemical
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3,4-Dichloro-Benzenesulfonylchlorid
Linshang Chemical
|
HS Code |
346012 |
| Chemical Formula | C6H3Cl3O2S |
| Molecular Weight | 245.51 |
| Appearance | Solid (usually white or off - white) |
| Physical State At Room Temp | Solid |
| Odor | Pungent |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like dichloromethane, chloroform |
| Melting Point | Around 49 - 53 °C |
| Boiling Point | Approximately 315 - 317 °C |
| Density | Data may vary, but typically around 1.64 g/cm³ |
| Hazard Class | Corrosive, can cause burns to skin, eyes and respiratory tract |
As an accredited 3,4-Dichloro-Benzenesulfonylchlorid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 3,4 - dichloro - benzenesulfonylchloride in a sealed, corrosion - resistant bottle. |
| Storage | 3,4 - Dichloro - benzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It must be kept in a tightly sealed container to prevent contact with moisture, as it can react with water. Store it separately from incompatible substances like bases, reducing agents, and reactive metals to avoid potential chemical reactions. |
| Shipping | 3,4 - dichloro - benzenesulfonyl chloride is a chemical that requires careful shipping. It should be packaged in corrosion - resistant containers, following regulations. Shipment must ensure protection from moisture and physical damage during transit. |
Competitive 3,4-Dichloro-Benzenesulfonylchlorid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 3,4-Dichloro-Benzenesulfonylchlorid in China?
As a trusted 3,4-Dichloro-Benzenesulfonylchlorid manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3,4-Dichloro-Benzenesulfonylchlorid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 3,4-dichlorobenzenesulfonyl chloride?
3,2,4-Difluorobenzoyl chloride is a crucial raw material in organic synthesis and has a wide range of uses in many fields.
In the field of pharmaceutical synthesis, it can be used as a key intermediate. For example, when synthesizing specific antibacterial drugs, 3,2,4-difluorobenzoyl chloride and compounds containing specific functional groups undergo a series of chemical reactions to construct molecular structures with unique antibacterial activities. The introduction of fluorine atoms on the benzene ring can change the electron cloud density and lipid solubility of drug molecules, and improve the biological activity and stability of drugs.
It also plays an important role in the field of pesticide synthesis. It can be used to prepare high-efficiency and low-toxicity insecticides, fungicides, etc. By reacting with other organic compounds to generate fluorinated pesticide active ingredients, with the characteristics of fluorine atoms, the effect of pesticides on pests or bacteria is enhanced, and the harm to the environment and toxicity to non-target organisms are reduced.
In the field of materials science, 3,2,4-difluorobenzoyl chloride can participate in the preparation of special polymer materials. For example, polymerize with monomers containing hydroxyl groups or amine groups to form fluorine-containing polymers. Due to the presence of fluorine atoms, these polymers often have excellent weather resistance, chemical corrosion resistance and low surface energy. They can be used in high-end fields such as aerospace, electronic appliances, etc., such as the manufacture of protective coatings for aerospace vehicles and insulating materials for electronic components.
In summary, 3,2,4-difluorobenzoyl chloride, with its unique chemical structure and reactivity, has shown indispensable value in many fields such as medicine, pesticides and materials, and has promoted technological progress and product innovation in various fields.
In the field of pharmaceutical synthesis, it can be used as a key intermediate. For example, when synthesizing specific antibacterial drugs, 3,2,4-difluorobenzoyl chloride and compounds containing specific functional groups undergo a series of chemical reactions to construct molecular structures with unique antibacterial activities. The introduction of fluorine atoms on the benzene ring can change the electron cloud density and lipid solubility of drug molecules, and improve the biological activity and stability of drugs.
It also plays an important role in the field of pesticide synthesis. It can be used to prepare high-efficiency and low-toxicity insecticides, fungicides, etc. By reacting with other organic compounds to generate fluorinated pesticide active ingredients, with the characteristics of fluorine atoms, the effect of pesticides on pests or bacteria is enhanced, and the harm to the environment and toxicity to non-target organisms are reduced.
In the field of materials science, 3,2,4-difluorobenzoyl chloride can participate in the preparation of special polymer materials. For example, polymerize with monomers containing hydroxyl groups or amine groups to form fluorine-containing polymers. Due to the presence of fluorine atoms, these polymers often have excellent weather resistance, chemical corrosion resistance and low surface energy. They can be used in high-end fields such as aerospace, electronic appliances, etc., such as the manufacture of protective coatings for aerospace vehicles and insulating materials for electronic components.
In summary, 3,2,4-difluorobenzoyl chloride, with its unique chemical structure and reactivity, has shown indispensable value in many fields such as medicine, pesticides and materials, and has promoted technological progress and product innovation in various fields.
What are the physical properties of 3,4-dichlorobenzenesulfonyl chloride?
3,2,4-Difluorobenzoyl chloride is an important compound in organic chemistry. Its physical properties are unique.
Looking at its properties, at room temperature, it often appears as a colorless to light yellow transparent liquid. This color state is distinct and easy to distinguish.
When it comes to odor, it has a strong pungent odor, and the smell is pungent and uncomfortable. This odor characteristic is very important when identifying this substance.
As for the boiling point, it is about 190-192 ° C. This boiling point value is an important indicator of its gas-liquid phase transition under specific conditions.
In terms of melting point, it is roughly around -20 ° C. The state of the melting point depends on its physical form in a low temperature environment.
Its density is about 1.422g/cm ³. This density data characterizes its mass characteristics per unit volume.
Solubility is also one of its important physical properties. It can be miscible in most organic solvents, such as benzene, toluene, dichloromethane, etc., but it is insoluble in water. This difference in solubility has far-reaching effects in organic synthesis and separation operations. The physical properties of 3,2,4-difluorobenzoyl chloride provide an important basis for experimental design, control of reaction conditions, and product separation and purification in the fields of organic synthesis, medicinal chemistry, and so on.
Looking at its properties, at room temperature, it often appears as a colorless to light yellow transparent liquid. This color state is distinct and easy to distinguish.
When it comes to odor, it has a strong pungent odor, and the smell is pungent and uncomfortable. This odor characteristic is very important when identifying this substance.
As for the boiling point, it is about 190-192 ° C. This boiling point value is an important indicator of its gas-liquid phase transition under specific conditions.
In terms of melting point, it is roughly around -20 ° C. The state of the melting point depends on its physical form in a low temperature environment.
Its density is about 1.422g/cm ³. This density data characterizes its mass characteristics per unit volume.
Solubility is also one of its important physical properties. It can be miscible in most organic solvents, such as benzene, toluene, dichloromethane, etc., but it is insoluble in water. This difference in solubility has far-reaching effects in organic synthesis and separation operations. The physical properties of 3,2,4-difluorobenzoyl chloride provide an important basis for experimental design, control of reaction conditions, and product separation and purification in the fields of organic synthesis, medicinal chemistry, and so on.
Is the chemical properties of 3,4-dichlorobenzenesulfonyl chloride stable?
3,4-Difluorobenzoyl chloride is a commonly used reagent in organic synthesis. Its chemical properties are relatively active and not very stable.
This compound contains an acyl chloride group, which is highly reactive. It is prone to hydrolysis in contact with water, and 3,4-difluorobenzoic acid and hydrogen chloride are rapidly formed. Its hydrolysis reaction is quite violent, which indicates that it is difficult to exist stably in humid environments.
3,4-difluorobenzoyl chloride can also alcoholyze with alcohols to form corresponding esters; it can undergo aminolysis with amines to form amide compounds. These reactions all reflect its active chemical properties, further indicating its poor stability.
When storing and using 3,4-difluorobenzoyl chloride, special measures are required. It should be stored in a dry, cool and well-ventilated place, and it must be strictly isolated from moisture and air to prevent it from deteriorating due to reactions such as hydrolysis. During operation, strict safety procedures must also be followed. Due to its high reactivity, and the corrosive and irritating properties of products such as hydrogen chloride, a little carelessness may cause harm to personnel and the environment. It can be seen that 3,4-difluorobenzoyl chloride is chemically active and has poor stability. Extra caution is required when handling.
This compound contains an acyl chloride group, which is highly reactive. It is prone to hydrolysis in contact with water, and 3,4-difluorobenzoic acid and hydrogen chloride are rapidly formed. Its hydrolysis reaction is quite violent, which indicates that it is difficult to exist stably in humid environments.
3,4-difluorobenzoyl chloride can also alcoholyze with alcohols to form corresponding esters; it can undergo aminolysis with amines to form amide compounds. These reactions all reflect its active chemical properties, further indicating its poor stability.
When storing and using 3,4-difluorobenzoyl chloride, special measures are required. It should be stored in a dry, cool and well-ventilated place, and it must be strictly isolated from moisture and air to prevent it from deteriorating due to reactions such as hydrolysis. During operation, strict safety procedures must also be followed. Due to its high reactivity, and the corrosive and irritating properties of products such as hydrogen chloride, a little carelessness may cause harm to personnel and the environment. It can be seen that 3,4-difluorobenzoyl chloride is chemically active and has poor stability. Extra caution is required when handling.
What are the precautions for storing and transporting 3,4-dichlorobenzenesulfonyl chloride?
3,4-Difluorobenzoyl chloride is a crucial raw material in organic synthesis. When storing and transporting, the following numbers should be paid attention to:
First, the storage place must be cool, dry and well ventilated. This substance is highly susceptible to reaction in contact with water. If placed in a humid environment, it may cause severe reactions, cause material deterioration, or even cause dangerous accidents. Therefore, the humidity of the warehouse should be strictly controlled, and it should be kept away from water sources, sinks and other moisture-prone places.
Second, it must be stored separately from oxidants and alkalis, and mixed storage should not be avoided. 3,4-Difluorobenzoyl chloride is chemically active and comes into contact with oxidants, or causes combustion or explosion; when it encounters alkalis, it is easy to have chemical reactions, which will damage the quality of materials and endanger storage safety.
Third, the storage container must be tightly sealed. It is generally advisable to choose corrosion-resistant materials, such as glass, specific plastics or metal materials, and ensure that the container is intact and there is no risk of leakage. Because of its strong corrosiveness and volatility, once leaked, it will not only pollute the environment, but also pose a great threat to human health.
Fourth, during transportation, it is necessary to strictly abide by relevant regulations and standards. Use professional transportation vehicles, and be equipped with necessary protective equipment and emergency disposal tools. Transportation personnel should also be professionally trained, familiar with the characteristics of the substance and emergency treatment methods, and need to protect against sun exposure, rain and high temperature during transportation.
Fifth, whether it is storage or transportation, clear warning signs should be installed. Show its corrosive, toxic and other dangerous characteristics, so that the contact person can see at a glance, improve vigilance, and prevent accidents.
First, the storage place must be cool, dry and well ventilated. This substance is highly susceptible to reaction in contact with water. If placed in a humid environment, it may cause severe reactions, cause material deterioration, or even cause dangerous accidents. Therefore, the humidity of the warehouse should be strictly controlled, and it should be kept away from water sources, sinks and other moisture-prone places.
Second, it must be stored separately from oxidants and alkalis, and mixed storage should not be avoided. 3,4-Difluorobenzoyl chloride is chemically active and comes into contact with oxidants, or causes combustion or explosion; when it encounters alkalis, it is easy to have chemical reactions, which will damage the quality of materials and endanger storage safety.
Third, the storage container must be tightly sealed. It is generally advisable to choose corrosion-resistant materials, such as glass, specific plastics or metal materials, and ensure that the container is intact and there is no risk of leakage. Because of its strong corrosiveness and volatility, once leaked, it will not only pollute the environment, but also pose a great threat to human health.
Fourth, during transportation, it is necessary to strictly abide by relevant regulations and standards. Use professional transportation vehicles, and be equipped with necessary protective equipment and emergency disposal tools. Transportation personnel should also be professionally trained, familiar with the characteristics of the substance and emergency treatment methods, and need to protect against sun exposure, rain and high temperature during transportation.
Fifth, whether it is storage or transportation, clear warning signs should be installed. Show its corrosive, toxic and other dangerous characteristics, so that the contact person can see at a glance, improve vigilance, and prevent accidents.
What is the preparation method of 3,4-dichlorobenzenesulfonyl chloride?
3,4-Difluorobenzoyl fluoride is a key intermediate in organic synthesis. The preparation method is as follows:
Start with 3,4-difluorobenzoic acid as raw material, place it in a reactor, and add an appropriate amount of thionyl chloride ($SOCl_2 $). Sulfoxide chloride acts as a chlorination agent, and reacts with 3,4-difluorobenzoic acid as follows: $R - COOH + SOCl_2\ longrightarrow R - COCl + SO_2 ↑ + HCl ↑ $ (here $R $represents 3,4-difluorophenyl). This reaction needs to be heated, and the temperature should be controlled at 60-80 ° C. During the reaction, sulfur dioxide and hydrogen chloride gas will escape, and the exhaust gas needs to be properly treated. After several hours of reaction, 3,4-difluorobenzoyl chloride can be prepared.
Then, transfer the prepared 3,4-difluorobenzoyl chloride to another reaction vessel and add anhydrous potassium fluoride ($KF $). The fluoride ion in $KF $will undergo nucleophilic substitution reaction with 3,4-difluorobenzoyl chloride, and $Cl ^ - $will be replaced by $F ^ - $, that is, $R-COCl + KF\ longrightarrow R-COF + KCl $. This reaction needs to be carried out in a polar aprotic solvent such as N, N-dimethylformamide (DMF), and the reaction temperature should be controlled at 120-150 ℃. The reaction process needs to be fully stirred to promote the reaction to proceed fully. After the reaction is completed, the product is separated and purified by means of reduced pressure distillation, etc., to obtain pure 3,4-difluorobenzoyl fluoride.
The entire preparation process must pay attention to the precise control of reaction conditions, such as temperature, reactant ratio and reaction time, and safety measures must be taken, because some reagents used are corrosive and toxic. At the same time, exhaust gas treatment and product purification are also crucial to ensure product quality and environmental safety.
Start with 3,4-difluorobenzoic acid as raw material, place it in a reactor, and add an appropriate amount of thionyl chloride ($SOCl_2 $). Sulfoxide chloride acts as a chlorination agent, and reacts with 3,4-difluorobenzoic acid as follows: $R - COOH + SOCl_2\ longrightarrow R - COCl + SO_2 ↑ + HCl ↑ $ (here $R $represents 3,4-difluorophenyl). This reaction needs to be heated, and the temperature should be controlled at 60-80 ° C. During the reaction, sulfur dioxide and hydrogen chloride gas will escape, and the exhaust gas needs to be properly treated. After several hours of reaction, 3,4-difluorobenzoyl chloride can be prepared.
Then, transfer the prepared 3,4-difluorobenzoyl chloride to another reaction vessel and add anhydrous potassium fluoride ($KF $). The fluoride ion in $KF $will undergo nucleophilic substitution reaction with 3,4-difluorobenzoyl chloride, and $Cl ^ - $will be replaced by $F ^ - $, that is, $R-COCl + KF\ longrightarrow R-COF + KCl $. This reaction needs to be carried out in a polar aprotic solvent such as N, N-dimethylformamide (DMF), and the reaction temperature should be controlled at 120-150 ℃. The reaction process needs to be fully stirred to promote the reaction to proceed fully. After the reaction is completed, the product is separated and purified by means of reduced pressure distillation, etc., to obtain pure 3,4-difluorobenzoyl fluoride.
The entire preparation process must pay attention to the precise control of reaction conditions, such as temperature, reactant ratio and reaction time, and safety measures must be taken, because some reagents used are corrosive and toxic. At the same time, exhaust gas treatment and product purification are also crucial to ensure product quality and environmental safety.
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