3,4-Dichlorobenzenesulphonyl Chloride
Linshang Chemical
HS Code |
644766 |
Chemical Formula | C6H3Cl3O2S |
Molar Mass | 245.51 g/mol |
Appearance | White to off - white crystalline solid |
Odor | Pungent |
Density | 1.64 g/cm³ (approximate) |
Melting Point | 58 - 60 °C |
Boiling Point | 279 - 281 °C |
Solubility In Water | Reacts with water |
Solubility In Organic Solvents | Soluble in many organic solvents like dichloromethane, chloroform |
Flash Point | 121 °C (approximate) |
Hazard Class | Corrosive |
As an accredited 3,4-Dichlorobenzenesulphonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 kg of 3,4 - dichlorobenzenesulphonyl Chloride in sealed chemical - resistant container. |
Storage | 3,4 - dichlorobenzenesulphonyl chloride should be stored in a cool, dry, and well - ventilated area. Keep it away from heat, flames, and oxidizing agents. Store it in a tightly closed container, preferably made of corrosion - resistant materials. This is because it is reactive and moisture - sensitive, and proper storage helps prevent decomposition and potential hazards. |
Shipping | 3,4 - dichlorobenzenesulphonyl chloride is a hazardous chemical. It should be shipped in accordance with strict regulations, using appropriate packaging to prevent leakage. The shipping must be carried out by professionals with proper safety measures. |
Competitive 3,4-Dichlorobenzenesulphonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 3,4-Dichlorobenzenesulphonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
First, it is used in the synthesis of medicine. In the preparation process of many drugs, 3,4-difluorobenzoyl chloride acts as a key intermediate. For example, by synthesizing specific antibacterial drugs, with its unique chemical structure, it can precisely react with other compounds to build a molecular structure with antibacterial activity, paving the way for pharmaceutical research and development. As Tiangong Kaiwu said: "Things in the world can be combined with each other to form new substances, and the synthesis of drugs follows this path." Through exquisite chemical reactions, 3,4-difluorobenzoyl chloride participates in it, giving drugs unique therapeutic effects.
Second, it is used in the preparation of pesticides. In the field of pesticides, it can chemically react with other substances to form highly efficient pesticides. For example, some pesticides, through the reaction of 3,4-difluorobenzoyl chloride with specific reagents, the resulting products are highly toxic to pests, but relatively friendly to the environment and helpful to agricultural pest control. Just as "Tiangong Kaiwu" mentioned: "In farming, pest control is essential, and the production of new products can solve this worry." 3,4-difluorobenzoyl chloride is used in the synthesis of pesticides, just like a strong defense line for agricultural production.
Third, it is used in the synthesis of dyes. Because of its active chemical properties, it can participate in the key steps of dye synthesis, so that the resulting dyes have bright colors and good stability. In the dye industry, 3,4-difluorobenzoyl chloride is like a delicate tool in the hands of skilled craftsmen, helping to create a variety of dye products. As "Tiangong Kaiwu" states: "The art of dyeing lies in the combination of materials, and the splendor of color comes from this." 3,4-difluorobenzoyl chloride plays an indispensable role in it, adding luster to the color of dyes.
Its boiling point is about 195-197 ° C. At this temperature, the liquid phase changes to the gas phase, and the molecules obtain enough energy to get rid of the liquid phase. The melting point is about -15 ° C. Below this temperature, the liquid solidifies into a solid state, and the molecular arrangement tends to be orderly from disorder.
The density is about 1.458g/cm ³, which is heavier than water. If mixed with water, it will sink to the bottom of the water. And volatile in air, because its boiling point is not very high, molecular movement causes surface molecules to escape.
In terms of solubility, it is slightly soluble in water, because it is an organic compound with hydrophobic groups, and the force between water molecules is weak. However, it is easily soluble in common organic solvents, such as dichloromethane, chloroform, ether, etc. Due to the principle of "similar miscibility", organic solvents and 3,2,4-difluorobenzoyl chloride have similar forces and are miscible.
The physical properties of this substance are of great significance in the fields of chemical production and organic synthesis. Data such as boiling point, melting point, and density help chemists design separation and purification processes. The solubility characteristics make it possible to select suitable solvents in organic synthesis to promote efficient reactions.
In this compound, the presence of fluorine atoms significantly affects its chemical properties. Fluorine atoms have strong electronegativity, resulting in changes in the distribution of electron clouds within the molecule, which enhances the polarity of the chemical bonds connected to them.
In nucleophilic substitution reactions, 3,4-difluorobenzoyl fluoride exhibits an active state. Because carbonyl carbons are affected by the electron-withdrawing effect of fluorine atoms, their positive electricity is enhanced, and they are more susceptible to attack by nucleophiles. For example, in contact with alcohol nucleophiles, alcoholysis reactions can occur to generate corresponding ester compounds. During the reaction, the oxygen atom of the alcohol attacks the carbonyl carbon with its lone pair electron, and then the fluoride ion leaves to complete the substitution process.
When interacting with amine nucleophiles, nucleophilic substitution can also occur to form amide products. The nitrogen atom of the amine acts as the nucleophilic center and binds to the carbonyl carbon, and the fluoride ion is separated. This is an important path for the preparation of specific amides.
In addition, due to the existence of the benzene ring conjugation system, 3,4-difluorobenzoyl fluoride can also participate in some reactions involving benzene rings. For example, under the action of a suitable catalyst, the electrophilic substitution reaction on the benzene ring can be carried out. Because the fluorine atom is an ortho-para-position group, the new substituent tends to enter the ortho or para-position of the benzene ring.
3,4-Difluorobenzoyl fluoride is widely used in the field of organic synthesis due to the atomic properties of fluorine and the interaction between benzene ring and carbonyl. It can be used as a key intermediate in the creation of many organic compounds with biological activity or special properties.
The first item concerns the preparation and storage of materials. This substance is highly corrosive and irritating. When preparing materials, it must be measured carefully and used accurately. The equipment used must also be resistant to corrosion. When storing, keep in a cool, dry and well-ventilated place, away from fire and heat sources, and avoid mixing with oxidants and alkalis to prevent dangerous chemical reactions.
Times and operating rules. During production operations, operators must wear professional protective equipment, such as corrosion-resistant protective clothing, protective gloves, goggles and gas masks, to ensure their own safety. The operation should be carried out in the fume hood to ensure air circulation and reduce the accumulation of harmful gases. And the operation process should strictly follow the established procedures, slowly add materials, and control the reaction temperature and rate to prevent accidents caused by overreaction.
The other is the maintenance and inspection of the equipment. The reaction kettle, pipes, valves and other equipment used need to be regularly maintained and inspected to check for corrosion and leakage. If there is any damage, it should be repaired or replaced immediately, and the equipment should never be operated "with disease". This is essential to ensure production safety and product quality.
There is also the treatment of waste. Waste generated in production, including unreacted raw materials, by-products and post-reaction residues, are toxic and corrosive and cannot be disposed of at will. It is necessary to collect, properly dispose of, or recycle and reuse, or dispose of harmlessly in accordance with relevant environmental protection regulations, so as not to pollute the environment.
End of the emergency strategy. The workshop should prepare and improve emergency facilities and equipment, such as eye washers, showers, fire extinguishers and emergency rescue drugs. And regularly organize employees to practice the emergency disposal process, so that everyone can respond calmly in the event of an emergency, take correct measures, and reduce the harm of the accident to a minimum.
All of these are carefully paid attention to in the production process of 3% 2C4-difluorobenzoyl chloride, so as to ensure production safety, efficiency, and achieve the expected goal.
In today's world, the field of medicinal chemistry is increasingly in demand for it. Due to the creation of many new drugs, 3% 2C4-difluorobenzaldehyde is relied on as a key starting material or intermediate. Taking the development of anti-cancer drugs as an example, researchers use their unique chemical structure and ingenious reaction design to build a molecular structure with high anti-cancer activity, which is expected to bring good news to cancer patients. Therefore, the vigorous development of the pharmaceutical industry has paved the way for a broad market.
Furthermore, the pesticide field also favors it. In the process of creating new pesticides, 3% 2C4-difluorobenzaldehyde can participate in the synthesis of pesticide ingredients with high selectivity, low toxicity and high efficiency. These pesticides can not only accurately eliminate pests and diseases, but also ensure the thriving growth of crops. They are in line with the current green agricultural development concept and meet the urgent needs of the market for environmentally friendly pesticides. The market potential is immeasurable.
In the field of materials science, with the rapid development of high-tech such as electronics and optics, the demand for special functional materials is also increasing. 3% 2C4-difluorobenzaldehyde can be used to synthesize new organic optoelectronic materials. These materials have shown excellent performance in the fields of organic Light Emitting Diode (OLED) and solar cells, earning them a place in the materials market.
However, although the market prospect is bright, it also faces various challenges. Optimization of its synthesis process and cost control are urgent. If it can develop more efficient, green and low-cost synthesis routes, it will be able to enhance its market competitiveness. In addition, environmental regulations are increasingly stringent, and the production process must ensure that the impact on the environment is minimized, which is also the key for enterprises to focus on.
Overall, 3% 2C4-difluorobenzaldehyde has a promising market prospect due to its wide application potential in the fields of medicine, pesticides, materials, etc. If the challenges are properly addressed, it will be able to shine brightly in the market.

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