Linshang Chemical
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3,4-Dichlorobromobenzene
Linshang Chemical
|
HS Code |
117833 |
| Chemical Formula | C6H3BrCl2 |
| Molar Mass | 225.90 g/mol |
| Appearance | Colorless to light - yellow liquid or solid |
| Density | 1.84 g/cm³ (estimated) |
| Boiling Point | 244 - 246 °C |
| Melting Point | 42 - 44 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
| Odor | Characteristic, pungent odor |
| Flash Point | 104 °C (closed cup, estimated) |
As an accredited 3,4-Dichlorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle of 3,4 - dichlorobromobenzene, tightly sealed for chemical storage. |
| Storage | 3,4 - Dichlorobromobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly closed container to prevent vapor leakage. Label the storage container clearly. Avoid storage near areas with potential for chemical reactions that could initiate decomposition or combustion. |
| Shipping | 3,4 - Dichlorobromobenzene is shipped in tightly - sealed, corrosion - resistant containers. These are carefully packaged to prevent breakage during transit, following strict regulations for hazardous chemicals transportation. |
Competitive 3,4-Dichlorobromobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 3,4-Dichlorobromobenzene in China?
As a trusted 3,4-Dichlorobromobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3,4-Dichlorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 3,4-dichlorobromobenzene?
3,2,4-Dihydroxybenzoic acid, also known as gentian acid, has a wide range of main uses.
In the field of medicine, this is a key intermediate. Many drug synthesis relies on it, such as some drugs with antipyretic, analgesic and anti-inflammatory effects. By modifying and modifying its chemical structure, new drugs with better efficacy and milder side effects can be developed. This is because its specific chemical structure can interact with specific biological targets in the human body to achieve the purpose of treating diseases.
In the cosmetic industry, 3,2,4-Dihydroxybenzoic acid is also important. Because it has certain antioxidant properties, it can effectively scavenge free radicals in the skin and slow down the process of skin aging. It can be added to skin care products to help maintain the health of the skin, making the skin firmer, smoother and more elastic.
In the chemical industry, it is an important raw material for the synthesis of many fine chemicals. It can be used to make special coatings, plastic additives, etc. By reacting with other compounds, it can give products excellent properties such as anti-corrosion and anti-oxidation, thereby improving the quality and performance of products.
Furthermore, in terms of food additives, 3,2,4-dihydroxybenzoic acid can be used as a preservative. It can inhibit the growth and reproduction of microorganisms in food, prolong the shelf life of food, and ensure the safety and stability of food. However, when used in food, relevant food safety standards and regulations must be strictly followed to protect the health of consumers.
In the field of medicine, this is a key intermediate. Many drug synthesis relies on it, such as some drugs with antipyretic, analgesic and anti-inflammatory effects. By modifying and modifying its chemical structure, new drugs with better efficacy and milder side effects can be developed. This is because its specific chemical structure can interact with specific biological targets in the human body to achieve the purpose of treating diseases.
In the cosmetic industry, 3,2,4-Dihydroxybenzoic acid is also important. Because it has certain antioxidant properties, it can effectively scavenge free radicals in the skin and slow down the process of skin aging. It can be added to skin care products to help maintain the health of the skin, making the skin firmer, smoother and more elastic.
In the chemical industry, it is an important raw material for the synthesis of many fine chemicals. It can be used to make special coatings, plastic additives, etc. By reacting with other compounds, it can give products excellent properties such as anti-corrosion and anti-oxidation, thereby improving the quality and performance of products.
Furthermore, in terms of food additives, 3,2,4-dihydroxybenzoic acid can be used as a preservative. It can inhibit the growth and reproduction of microorganisms in food, prolong the shelf life of food, and ensure the safety and stability of food. However, when used in food, relevant food safety standards and regulations must be strictly followed to protect the health of consumers.
What are the physical properties of 3,4-dichlorobromobenzene?
3,4-Difluorobromobenzene is also an organic compound. Its physical properties are worth exploring.
Looking at its properties, at room temperature, 3,4-difluorobromobenzene is a colorless to light yellow transparent liquid. Its color is pure and its light transmittance is good, which shows the stability and order of its molecular structure.
When it comes to the boiling point, it is between 157 ° C and 159 ° C. This boiling point value shows that in order to convert it from liquid to gas, a specific amount of heat needs to be applied, which shows the degree of intermolecular force. When the temperature rises, the molecules are energized, break free from each other and form a gaseous state.
As for the density, it is about 1.716g/mL. This value reflects its mass per unit volume, which is heavier than the common water. When placed in water, it will sink to the bottom. Due to the close arrangement of molecules, the type and structure of atoms in the inner atoms cause dense mass distribution.
In terms of solubility, 3,4-difluorobromobenzene is insoluble in water. This is because its molecular polarity is quite different from that of water molecules. According to the principle of similar compatibility, the two are difficult to dissolve. However, it has good solubility in organic solvents, such as ethanol and ether. Because organic solvents and 3,4-difluorobrobenzene molecules are similar in force phase, they can dissolve each other to form a uniform solution.
And it has a certain degree of volatility, which gradually evaporates in the air and emits a unique odor. This volatilization characteristic is not only related to its boiling point, but also related to the thermal motion of molecules. Molecules move at all times, and some surface molecules can escape from the liquid surface, causing them to evaporate.
All these physical properties are of crucial significance in many fields such as organic synthesis and drug development, providing a solid foundation for practical applications.
Looking at its properties, at room temperature, 3,4-difluorobromobenzene is a colorless to light yellow transparent liquid. Its color is pure and its light transmittance is good, which shows the stability and order of its molecular structure.
When it comes to the boiling point, it is between 157 ° C and 159 ° C. This boiling point value shows that in order to convert it from liquid to gas, a specific amount of heat needs to be applied, which shows the degree of intermolecular force. When the temperature rises, the molecules are energized, break free from each other and form a gaseous state.
As for the density, it is about 1.716g/mL. This value reflects its mass per unit volume, which is heavier than the common water. When placed in water, it will sink to the bottom. Due to the close arrangement of molecules, the type and structure of atoms in the inner atoms cause dense mass distribution.
In terms of solubility, 3,4-difluorobromobenzene is insoluble in water. This is because its molecular polarity is quite different from that of water molecules. According to the principle of similar compatibility, the two are difficult to dissolve. However, it has good solubility in organic solvents, such as ethanol and ether. Because organic solvents and 3,4-difluorobrobenzene molecules are similar in force phase, they can dissolve each other to form a uniform solution.
And it has a certain degree of volatility, which gradually evaporates in the air and emits a unique odor. This volatilization characteristic is not only related to its boiling point, but also related to the thermal motion of molecules. Molecules move at all times, and some surface molecules can escape from the liquid surface, causing them to evaporate.
All these physical properties are of crucial significance in many fields such as organic synthesis and drug development, providing a solid foundation for practical applications.
Is the chemical properties of 3,4-dichlorobromobenzene stable?
The chemical properties of 3,4-difluorobromobenzene are still stable under normal temperature and pressure. This substance has the typical characteristics of halogenated aromatics.
In terms of its stability, the carbon-fluorine bond and the carbon-bromine bond are quite firm. In the case of the carbon-fluorine bond, due to the extremely high electronegativity of the fluorine atom, the bond energy is very large, and higher energy is required to break it. Although the carbon-bromine bond is slightly weaker than the carbon-fluorine bond, it still has certain stability. Therefore, 3,4-difluorobrobenzene is not easy to spontaneously decompose under normal conditions.
In case of special conditions, its stability will also change. In case of high temperature, open flame or strong oxidizing agent, the reaction may be initiated. At high temperature, the carbon-halogen bond may break due to obtaining sufficient energy, and then reactions such as substitution and elimination occur. In the presence of strong oxidizing agents, the substituents on the benzene ring may be oxidized to change their chemical structure.
In the field of organic synthesis, 3,4-difluorobrobenzene is often used as an important intermediate. Because of its bromine and fluorine atoms, the reactivity of halogenated hydrocarbons can be used to introduce various functional groups through nucleophilic substitution reactions to construct more complex organic molecules. In this process, the stability of 3,4-difluorobrobenzene can ensure that the reaction proceeds according to the expected path and reduce unnecessary side reactions.
In summary, 3,4-difluorobromobenzene is relatively stable chemically in the general environment, but under specific conditions, its stability may be affected, and corresponding chemical reactions may occur.
In terms of its stability, the carbon-fluorine bond and the carbon-bromine bond are quite firm. In the case of the carbon-fluorine bond, due to the extremely high electronegativity of the fluorine atom, the bond energy is very large, and higher energy is required to break it. Although the carbon-bromine bond is slightly weaker than the carbon-fluorine bond, it still has certain stability. Therefore, 3,4-difluorobrobenzene is not easy to spontaneously decompose under normal conditions.
In case of special conditions, its stability will also change. In case of high temperature, open flame or strong oxidizing agent, the reaction may be initiated. At high temperature, the carbon-halogen bond may break due to obtaining sufficient energy, and then reactions such as substitution and elimination occur. In the presence of strong oxidizing agents, the substituents on the benzene ring may be oxidized to change their chemical structure.
In the field of organic synthesis, 3,4-difluorobrobenzene is often used as an important intermediate. Because of its bromine and fluorine atoms, the reactivity of halogenated hydrocarbons can be used to introduce various functional groups through nucleophilic substitution reactions to construct more complex organic molecules. In this process, the stability of 3,4-difluorobrobenzene can ensure that the reaction proceeds according to the expected path and reduce unnecessary side reactions.
In summary, 3,4-difluorobromobenzene is relatively stable chemically in the general environment, but under specific conditions, its stability may be affected, and corresponding chemical reactions may occur.
What are the preparation methods of 3,4-dichlorobromobenzene?
3,4-Difluorobenzoic acid is an important intermediate in organic synthesis. There are many preparation methods, which are described in detail as follows:
1. ** Halogen exchange method with 3,4-dichlorobenzoic acid as raw material **:
- This is a common preparation route. In a suitable organic solvent, such as N, N-dimethylformamide (DMF), 3,4-dichlorobenzoic acid is reacted with fluorinated reagents, such as potassium fluoride, under the action of a catalyst.
- The reaction principle is that halogen atoms can be exchanged under specific conditions. The catalysts used are often crown ethers, such as 18-crown-6, which can significantly improve the solubility of potassium fluoride in organic solvents, thereby accelerating the reaction rate.
- During the reaction, the reaction temperature and time need to be strictly controlled, usually the temperature is maintained at 150-200 ° C, and the reaction takes several hours to ten hours. After the reaction is completed, high-purity 3,4-difluorobenzoic acid can be obtained through cooling, filtration, washing, recrystallization and other processes.
2. ** Multi-step synthesis method using o-xylene as the starting material **:
- First, o-xylene is halogenated under specific conditions, and chlorine atoms can be introduced into the benzene ring under the action of light or initiator to generate 3,4-dichloro-o-xylene.
- Subsequently, 3,4-dichloro-o-xylene is oxidized, and a strong oxidant such as potassium permanganate is used to oxidize methyl to carboxyl groups to obtain 3,4-dichlorobenzoic acid.
- Finally, 3,4-dichlorobenzoic acid is converted into 3,4-dichlorobenzoic acid according to the halogen exchange method. Although this method has many steps, the raw materials are relatively easy to obtain and the cost is relatively low.
3. ** Oxidation method using 3,4-difluorotoluene as raw material **:
- 3,4-difluorotoluene can be oxidized by suitable oxidants to obtain 3,4-difluorobenzoic acid. Commonly used oxidants include oxygen, air, etc. Transition metal salts are used as catalysts, such as cobalt salts, manganese salts, etc., and bromide is used as co-catalyst.
- This reaction is usually carried out in the liquid phase. At a certain temperature and pressure, the methyl group of 3,4-difluorotoluene is gradually oxidized to a carboxyl group by oxygen or air. This method has the advantages of relatively mild reaction conditions and little environmental pollution, but it requires high reaction equipment, and the choice and dosage of catalyst have a great impact on the reaction.
1. ** Halogen exchange method with 3,4-dichlorobenzoic acid as raw material **:
- This is a common preparation route. In a suitable organic solvent, such as N, N-dimethylformamide (DMF), 3,4-dichlorobenzoic acid is reacted with fluorinated reagents, such as potassium fluoride, under the action of a catalyst.
- The reaction principle is that halogen atoms can be exchanged under specific conditions. The catalysts used are often crown ethers, such as 18-crown-6, which can significantly improve the solubility of potassium fluoride in organic solvents, thereby accelerating the reaction rate.
- During the reaction, the reaction temperature and time need to be strictly controlled, usually the temperature is maintained at 150-200 ° C, and the reaction takes several hours to ten hours. After the reaction is completed, high-purity 3,4-difluorobenzoic acid can be obtained through cooling, filtration, washing, recrystallization and other processes.
2. ** Multi-step synthesis method using o-xylene as the starting material **:
- First, o-xylene is halogenated under specific conditions, and chlorine atoms can be introduced into the benzene ring under the action of light or initiator to generate 3,4-dichloro-o-xylene.
- Subsequently, 3,4-dichloro-o-xylene is oxidized, and a strong oxidant such as potassium permanganate is used to oxidize methyl to carboxyl groups to obtain 3,4-dichlorobenzoic acid.
- Finally, 3,4-dichlorobenzoic acid is converted into 3,4-dichlorobenzoic acid according to the halogen exchange method. Although this method has many steps, the raw materials are relatively easy to obtain and the cost is relatively low.
3. ** Oxidation method using 3,4-difluorotoluene as raw material **:
- 3,4-difluorotoluene can be oxidized by suitable oxidants to obtain 3,4-difluorobenzoic acid. Commonly used oxidants include oxygen, air, etc. Transition metal salts are used as catalysts, such as cobalt salts, manganese salts, etc., and bromide is used as co-catalyst.
- This reaction is usually carried out in the liquid phase. At a certain temperature and pressure, the methyl group of 3,4-difluorotoluene is gradually oxidized to a carboxyl group by oxygen or air. This method has the advantages of relatively mild reaction conditions and little environmental pollution, but it requires high reaction equipment, and the choice and dosage of catalyst have a great impact on the reaction.
What are the precautions for the storage and transportation of 3,4-dichlorobromobenzene?
3% 2C4-dihydrofuran is a highly toxic substance. It must be stored and transported with extreme caution and must not be slack in the slightest.
First, when storing, you must find a cool and well-ventilated place. This substance is highly volatile when heated, and even causes the risk of explosion, so it is the first thing to stay away from heat and fire sources. The temperature of the warehouse should be strictly controlled within the appropriate range, and it must not be too high. And the humidity of the warehouse should also be paid attention to. If it is too wet or causes it to deteriorate, it will affect its quality and safety.
Second, the choice of storage containers is crucial. When using containers with excellent corrosion resistance and sealing. Due to the active chemical properties of 3% 2C4-dihydrofuran, ordinary materials may react chemically with it, causing damage to the container, which in turn leaks, causing a catastrophe. On the container, it is also necessary to clearly mark its name, nature, harm and other key information for identification.
Third, during transportation, be sure to ensure stability. Violent vibration or collision may cause the container to break and cause it to leak. Transportation vehicles should also be equipped with corresponding emergency equipment and protective equipment, just in case. Escort personnel need to be professionally trained, familiar with its characteristics and emergency handling methods, and always be vigilant.
Fourth, regardless of storage or transportation, relevant regulations and standards should be followed. Do not operate illegally for a while. And regularly check the storage environment and transportation equipment to detect and eliminate hidden dangers in time. A little negligence may cause serious consequences, endangering personal safety and the environment.
First, when storing, you must find a cool and well-ventilated place. This substance is highly volatile when heated, and even causes the risk of explosion, so it is the first thing to stay away from heat and fire sources. The temperature of the warehouse should be strictly controlled within the appropriate range, and it must not be too high. And the humidity of the warehouse should also be paid attention to. If it is too wet or causes it to deteriorate, it will affect its quality and safety.
Second, the choice of storage containers is crucial. When using containers with excellent corrosion resistance and sealing. Due to the active chemical properties of 3% 2C4-dihydrofuran, ordinary materials may react chemically with it, causing damage to the container, which in turn leaks, causing a catastrophe. On the container, it is also necessary to clearly mark its name, nature, harm and other key information for identification.
Third, during transportation, be sure to ensure stability. Violent vibration or collision may cause the container to break and cause it to leak. Transportation vehicles should also be equipped with corresponding emergency equipment and protective equipment, just in case. Escort personnel need to be professionally trained, familiar with its characteristics and emergency handling methods, and always be vigilant.
Fourth, regardless of storage or transportation, relevant regulations and standards should be followed. Do not operate illegally for a while. And regularly check the storage environment and transportation equipment to detect and eliminate hidden dangers in time. A little negligence may cause serious consequences, endangering personal safety and the environment.
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