Linshang Chemical
PRODUCTS
3,5-Dichloro-4-Fluoronitrobenzene
Linshang Chemical
|
HS Code |
406927 |
| Chemical Formula | C6H2Cl2FNO2 |
| Molecular Weight | 208.0 |
| Appearance | Solid (usually pale yellow to off - white) |
| Melting Point | Around 50 - 55°C |
| Boiling Point | Approximately 230 - 240°C |
| Density | 1.60 g/cm³ (approximate) |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, acetone, etc. |
| Vapor Pressure | Low at room temperature |
| Flash Point | Around 100 - 110°C |
As an accredited 3,5-Dichloro-4-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 3,5 - dichloro - 4 - fluoronitrobenzene packaged in a sealed plastic drum. |
| Storage | 3,5 - dichloro - 4 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and incompatible substances like strong oxidizers, reducing agents, and bases. Store it in tightly sealed containers to prevent leakage and exposure to air and moisture, which could potentially lead to decomposition or chemical reactions. |
| Shipping | 3,5 - dichloro - 4 - fluoronitrobenzene is shipped in sealed, corrosion - resistant containers. It's transported under strict safety protocols, avoiding exposure to heat, ignition sources, and incompatible substances to ensure safe delivery. |
Competitive 3,5-Dichloro-4-Fluoronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 3,5-Dichloro-4-Fluoronitrobenzene in China?
As a trusted 3,5-Dichloro-4-Fluoronitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3,5-Dichloro-4-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 3,5-dichloro-4-fluoronitrobenzene?
3,5-Dioxy-4-hydroxymethylfuranylnaphthalene is used in the Pharmacopoeia of Dan Formula, and its use is quite unique. It is often used as a supplement to help the good and remove evil in the way of medical treatment. Cover because it has the effect of reconciling qi and blood, dredging meridians and collaterals, and can help the recovery of viscera functions. In various diseases, it has the effect of improving the discomfort caused by poor qi and blood, and blocked meridians, such as limb pain, chest and abdomen stuffiness, etc.
And it is also involved in the refining of pill sand. In the process of cauldron burning and mercury-lead synthesis, adding this substance can make the texture of the pill purer, the medicinal properties are more peaceful, and the effect of the pill can be enhanced. The ancients believed that the medicinal pills refined with this substance could strengthen the body and prolong life. Although it may be exaggerated, it can also be seen that it is important in the process of alchemy.
In addition, in the method of processing herbs, it is also used as a reference. With its compatibility with various herbs, it can lead the medicine to the meridian, so that the effect of the medicine can reach the disease and improve the overall effectiveness of the medicine. Or use it to fry the soup first, and then use this soup to make other medicines; or grind it into the end and mix it with other medicines, all of which are for the purpose of achieving the best medicinal use. From this perspective, 3,5-dioxy-4-hydroxymethylfuranyl naphthalene plays an indispensable role in ancient medicine alchemy and herbal processing, and is an important part of traditional alchemy.
And it is also involved in the refining of pill sand. In the process of cauldron burning and mercury-lead synthesis, adding this substance can make the texture of the pill purer, the medicinal properties are more peaceful, and the effect of the pill can be enhanced. The ancients believed that the medicinal pills refined with this substance could strengthen the body and prolong life. Although it may be exaggerated, it can also be seen that it is important in the process of alchemy.
In addition, in the method of processing herbs, it is also used as a reference. With its compatibility with various herbs, it can lead the medicine to the meridian, so that the effect of the medicine can reach the disease and improve the overall effectiveness of the medicine. Or use it to fry the soup first, and then use this soup to make other medicines; or grind it into the end and mix it with other medicines, all of which are for the purpose of achieving the best medicinal use. From this perspective, 3,5-dioxy-4-hydroxymethylfuranyl naphthalene plays an indispensable role in ancient medicine alchemy and herbal processing, and is an important part of traditional alchemy.
What are the physical properties of 3,5-dichloro-4-fluoronitrobenzene?
3,5-Difluoro-4-cyanoanisole is an organic compound with specific physical properties. It is usually in a solid state at room temperature and pressure, and white to off-white crystalline powders are common in appearance. This form is easy to store and transport. The melting point of
is about [X] ° C to [X] ° C. This melting point characteristic is of great significance in the field of organic synthesis. In a specific chemical reaction, the reaction process and product purity can be determined according to its melting point. For example, when purifying the product by recrystallization, if the melting point of the product matches the melting point of 3,5-difluoro-4-cyanoanisole recorded in the literature, or the difference is within a very small range, it can be preliminarily inferred that the purity of the product is high.
In terms of boiling point, it is about [X] ° C under normal pressure conditions. Boiling point information is extremely critical in chemical operations such as distillation separation and rectification. When 3,5-difluoro-4-cyanoanisole needs to be separated from the reaction mixture, the distillation temperature can be precisely controlled according to its boiling point to achieve effective separation.
In terms of solubility, the compound exhibits good solubility in organic solvents such as dichloromethane, chloroform, and N, N-dimethylformamide (DMF). This solubility facilitates organic synthesis. Many organic reactions need to be carried out in a solution environment. Good solubility ensures that the reactants are fully contacted and the reaction rate and yield are improved. For example, in the nucleophilic substitution reaction using 3,5-difluoro-4-cyanisole as a raw material, selecting a suitable organic solvent to dissolve the reactants can make the reaction proceed efficiently. However, its poor solubility in water also limits its application in aqueous reaction systems to a certain extent.
In terms of density, it is about [X] g/cm ³. Density data is indispensable when chemical production involves material measurement and container design. Knowing the density can accurately calculate the mass of a certain volume of 3,5-difluoro-4-cyanoanisole, and then rationally plan the reaction feed amount.
is about [X] ° C to [X] ° C. This melting point characteristic is of great significance in the field of organic synthesis. In a specific chemical reaction, the reaction process and product purity can be determined according to its melting point. For example, when purifying the product by recrystallization, if the melting point of the product matches the melting point of 3,5-difluoro-4-cyanoanisole recorded in the literature, or the difference is within a very small range, it can be preliminarily inferred that the purity of the product is high.
In terms of boiling point, it is about [X] ° C under normal pressure conditions. Boiling point information is extremely critical in chemical operations such as distillation separation and rectification. When 3,5-difluoro-4-cyanoanisole needs to be separated from the reaction mixture, the distillation temperature can be precisely controlled according to its boiling point to achieve effective separation.
In terms of solubility, the compound exhibits good solubility in organic solvents such as dichloromethane, chloroform, and N, N-dimethylformamide (DMF). This solubility facilitates organic synthesis. Many organic reactions need to be carried out in a solution environment. Good solubility ensures that the reactants are fully contacted and the reaction rate and yield are improved. For example, in the nucleophilic substitution reaction using 3,5-difluoro-4-cyanisole as a raw material, selecting a suitable organic solvent to dissolve the reactants can make the reaction proceed efficiently. However, its poor solubility in water also limits its application in aqueous reaction systems to a certain extent.
In terms of density, it is about [X] g/cm ³. Density data is indispensable when chemical production involves material measurement and container design. Knowing the density can accurately calculate the mass of a certain volume of 3,5-difluoro-4-cyanoanisole, and then rationally plan the reaction feed amount.
What are the synthesis methods of 3,5-dichloro-4-fluoronitrobenzene?
The synthesis method of 3,5-dihydroxy-4-methoxybenzaldehyde is not directly described in Tiangong Kaiwu, but it can be deduced by analogy from traditional organic synthesis ideas.
Ancient organic synthesis is mostly derived from the extraction and transformation of natural materials. You can find natural plants rich in such structural fragments, such as some plants with phenolic components. First extract with water or organic solvents, such as soaking in boiling soup, so that the substances containing the target ingredients are dissolved, and then filtered to remove their residues. After purification by distillation, recrystallization, etc., or a purer product can be obtained.
Or it can be transformed through chemistry. Using common phenolic compounds as starting materials, phenols are easily obtained in the natural world. First, an appropriate alkylation reagent, such as halogenated methane, is reacted under alkaline conditions to introduce a methoxy group. This is the idea of simulating the ancient method of ether production. The base can assist in the formation of phenolic hydroxyl negative ions, nucleophilic attack on the carbon atoms of halogenated methane, and form a methoxy group. After the oxidation step, the hydroxyl group is introduced at a suitable check point, which can be achieved by a mild oxidizing agent, such as oxygen in the air, with the assistance of a catalyst. Catalysts or natural metal salts, such as copper salts, catalyze the oxidation of phenols to the corresponding aldehyde groups and hydroxylated products.
Or starting from aldehyde compounds, through reactions such as hydroxyaldehyde condensation, the phenyl ring structure is constructed, and the desired hydroxyl group and methoxy group are gradually introduced. Hydroxyaldehyde condensation can occur in an alkaline environment, with addition condensation between aldehyde molecules, followed by cyclization, oxidation, substitution and other series of reactions to shape the structure of the target molecule. Although these steps are complicated, in ancient chemical operations, they can also be achieved gradually by controlling the reaction conditions, such as temperature, time, and the proportion of reactants. In short, although its synthesis is not detailed in "Tiangong Kaiwu", it may be possible to explore a feasible method according to the wisdom of traditional chemical operations.
Ancient organic synthesis is mostly derived from the extraction and transformation of natural materials. You can find natural plants rich in such structural fragments, such as some plants with phenolic components. First extract with water or organic solvents, such as soaking in boiling soup, so that the substances containing the target ingredients are dissolved, and then filtered to remove their residues. After purification by distillation, recrystallization, etc., or a purer product can be obtained.
Or it can be transformed through chemistry. Using common phenolic compounds as starting materials, phenols are easily obtained in the natural world. First, an appropriate alkylation reagent, such as halogenated methane, is reacted under alkaline conditions to introduce a methoxy group. This is the idea of simulating the ancient method of ether production. The base can assist in the formation of phenolic hydroxyl negative ions, nucleophilic attack on the carbon atoms of halogenated methane, and form a methoxy group. After the oxidation step, the hydroxyl group is introduced at a suitable check point, which can be achieved by a mild oxidizing agent, such as oxygen in the air, with the assistance of a catalyst. Catalysts or natural metal salts, such as copper salts, catalyze the oxidation of phenols to the corresponding aldehyde groups and hydroxylated products.
Or starting from aldehyde compounds, through reactions such as hydroxyaldehyde condensation, the phenyl ring structure is constructed, and the desired hydroxyl group and methoxy group are gradually introduced. Hydroxyaldehyde condensation can occur in an alkaline environment, with addition condensation between aldehyde molecules, followed by cyclization, oxidation, substitution and other series of reactions to shape the structure of the target molecule. Although these steps are complicated, in ancient chemical operations, they can also be achieved gradually by controlling the reaction conditions, such as temperature, time, and the proportion of reactants. In short, although its synthesis is not detailed in "Tiangong Kaiwu", it may be possible to explore a feasible method according to the wisdom of traditional chemical operations.
What are the precautions for storing and transporting 3,5-dichloro-4-fluoronitrobenzene?
When storing and transporting 3% 2C5-difluoro-4-acetamidobenzene, pay close attention to the following:
First, this substance has specific chemical properties and is extremely sensitive to temperature and humidity. When storing, choose a dry, cool and well-ventilated place, and do not expose it to high temperature or humidity. If the temperature and humidity are inappropriate, it may cause chemical reactions, damage its quality, or even cause safety risks.
Second, because it may be toxic and corrosive, during operation and transportation, the operator must strictly follow safety procedures. Wear protective clothing, protective gloves, goggles, etc., to prevent contact with skin, eyes, etc., causing injury. And the operating environment should be well ventilated to avoid inhalation of harmful gases.
Third, during transportation, ensure that the packaging is intact. Packaging materials should be able to effectively resist external impact and chemical attack to prevent leakage. If a leak occurs, it will not only waste materials, but also pollute the environment and pose a threat to surrounding organisms. Once a leak occurs, it needs to be dealt with immediately according to the established emergency plan, cleaned up in time to prevent proliferation.
Fourth, the storage place should be separated from oxidants, acids, alkalis, etc., and must not be mixed. Due to its active chemical properties, contact with these substances can easily trigger violent chemical reactions, such as combustion, explosion and other serious accidents.
Fifth, whether it is storage or transportation, detailed records must be kept. The records cover the warehousing time, quantity, storage conditions changes, transportation routes, etc., to facilitate traceability and management. If there are any abnormalities, the cause can be quickly identified and promptly disposed of.
First, this substance has specific chemical properties and is extremely sensitive to temperature and humidity. When storing, choose a dry, cool and well-ventilated place, and do not expose it to high temperature or humidity. If the temperature and humidity are inappropriate, it may cause chemical reactions, damage its quality, or even cause safety risks.
Second, because it may be toxic and corrosive, during operation and transportation, the operator must strictly follow safety procedures. Wear protective clothing, protective gloves, goggles, etc., to prevent contact with skin, eyes, etc., causing injury. And the operating environment should be well ventilated to avoid inhalation of harmful gases.
Third, during transportation, ensure that the packaging is intact. Packaging materials should be able to effectively resist external impact and chemical attack to prevent leakage. If a leak occurs, it will not only waste materials, but also pollute the environment and pose a threat to surrounding organisms. Once a leak occurs, it needs to be dealt with immediately according to the established emergency plan, cleaned up in time to prevent proliferation.
Fourth, the storage place should be separated from oxidants, acids, alkalis, etc., and must not be mixed. Due to its active chemical properties, contact with these substances can easily trigger violent chemical reactions, such as combustion, explosion and other serious accidents.
Fifth, whether it is storage or transportation, detailed records must be kept. The records cover the warehousing time, quantity, storage conditions changes, transportation routes, etc., to facilitate traceability and management. If there are any abnormalities, the cause can be quickly identified and promptly disposed of.
What are the effects of 3,5-dichloro-4-fluoronitrobenzene on the environment and human health?
3,5-Difluoro-4-cyanoanisole is a chemical commonly used in organic synthesis. However, it does have many effects on the environment and human health, as detailed below:
Effects on the environment
1. ** Ecotoxicity **: If this substance is released into the environment, it may cause toxicity to aquatic organisms. In aquatic ecosystems, it may interfere with the physiological processes of aquatic organisms, such as affecting the respiration and reproduction of fish, resulting in stunted growth, decreased reproductive capacity, and even death. It also has similar effects on plankton and benthic organisms, disrupting the balance of aquatic ecosystems.
2. ** Bioaccumulation **: Because it has certain chemical stability, it may accumulate in organisms. When low-level organisms ingest environmental media containing this substance, it is difficult to metabolize and excrete it. It is passed along with the food chain, and the concentration gradually increases in high-level organisms, which affects the structure and function of the food chain of the entire ecosystem.
3. ** Persistence **: In environmental media such as soil and water, 3,5-difluoro-4-cyanoanisole degrades slowly and remains for a long time. It continues to cause pressure on the surrounding environment, affect soil fertility and water quality, and change the chemical composition and properties of the ecological environment.
Effects on human health
1. ** Skin and eye irritation **: Direct contact with the substance, or irritation to the skin and eyes. Causes redness, swelling, itching, pain and other symptoms on the skin, and dermatitis in severe cases; contact with the eyes, can cause eye tingling, tears, redness and swelling, damage eye tissue, and affect vision.
2. ** Respiratory system effects **: Inhalation of dust or volatile gases containing this substance can irritate the respiratory tract, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure, or damage to respiratory mucosa, increases the risk of respiratory diseases, such as bronchitis, pneumonia, etc.
3. ** Potential toxicity **: Animal experiments have shown that long-term exposure to a certain dose of 3,5-difluoro-4-cyanoanisole may affect the function of the nervous system and immune system. Interferes with the transmission of neurotransmitters, causes nervous system dysfunction, headaches, dizziness, fatigue and other symptoms; affects the activity and function of immune cells, reduces the body's immunity, and makes people vulnerable to pathogens. And studies suggest that it may have potential carcinogenicity. Although the relevant evidence in the human body is not sufficient, it cannot be ignored.
Therefore, when using 3,5-difluoro-4-cyanoanisole, strict protective measures must be taken to reduce its harm to the environment and human health.
Effects on the environment
1. ** Ecotoxicity **: If this substance is released into the environment, it may cause toxicity to aquatic organisms. In aquatic ecosystems, it may interfere with the physiological processes of aquatic organisms, such as affecting the respiration and reproduction of fish, resulting in stunted growth, decreased reproductive capacity, and even death. It also has similar effects on plankton and benthic organisms, disrupting the balance of aquatic ecosystems.
2. ** Bioaccumulation **: Because it has certain chemical stability, it may accumulate in organisms. When low-level organisms ingest environmental media containing this substance, it is difficult to metabolize and excrete it. It is passed along with the food chain, and the concentration gradually increases in high-level organisms, which affects the structure and function of the food chain of the entire ecosystem.
3. ** Persistence **: In environmental media such as soil and water, 3,5-difluoro-4-cyanoanisole degrades slowly and remains for a long time. It continues to cause pressure on the surrounding environment, affect soil fertility and water quality, and change the chemical composition and properties of the ecological environment.
Effects on human health
1. ** Skin and eye irritation **: Direct contact with the substance, or irritation to the skin and eyes. Causes redness, swelling, itching, pain and other symptoms on the skin, and dermatitis in severe cases; contact with the eyes, can cause eye tingling, tears, redness and swelling, damage eye tissue, and affect vision.
2. ** Respiratory system effects **: Inhalation of dust or volatile gases containing this substance can irritate the respiratory tract, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure, or damage to respiratory mucosa, increases the risk of respiratory diseases, such as bronchitis, pneumonia, etc.
3. ** Potential toxicity **: Animal experiments have shown that long-term exposure to a certain dose of 3,5-difluoro-4-cyanoanisole may affect the function of the nervous system and immune system. Interferes with the transmission of neurotransmitters, causes nervous system dysfunction, headaches, dizziness, fatigue and other symptoms; affects the activity and function of immune cells, reduces the body's immunity, and makes people vulnerable to pathogens. And studies suggest that it may have potential carcinogenicity. Although the relevant evidence in the human body is not sufficient, it cannot be ignored.
Therefore, when using 3,5-difluoro-4-cyanoanisole, strict protective measures must be taken to reduce its harm to the environment and human health.
Scan to WhatsApp
