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3,5-Dichlorobenzene-1-Carbohydrazide
Linshang Chemical
|
HS Code |
400009 |
| Chemical Formula | C7H6Cl2N2O |
| Molecular Weight | 205.04 |
| Appearance | Solid (usually white or off - white powder) |
| Melting Point | Typically in a certain range, e.g., around 180 - 190 °C (needs precise determination) |
| Boiling Point | Decomposes before boiling under normal conditions |
| Solubility In Water | Poorly soluble in water |
| Solubility In Organic Solvents | Soluble in some organic solvents like ethanol, dichloromethane |
| Density | Specific density value needs experimental determination |
| Purity | Can be of various purities, e.g., 95%+, 98%+ depending on production |
| Odor | May have a faint, characteristic odor |
| Stability | Stable under normal storage conditions, but may react with strong oxidizing agents |
As an accredited 3,5-Dichlorobenzene-1-Carbohydrazide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 g of 3,5 - dichlorobenzene - 1 - carbohydrazide in a sealed, labeled chemical - grade container. |
| Storage | 3,5 - dichlorobenzene - 1 - carbohydrazide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and direct sunlight. Store in a tightly sealed container to prevent moisture absorption and contact with air. Separate from oxidizing agents and incompatible substances to avoid potential reactions. |
| Shipping | 3,5 - dichlorobenzene - 1 - carbohydrazide is shipped in well - sealed containers, following strict chemical handling protocols. Packaging ensures protection from moisture and physical damage during transit to prevent any safety risks. |
Competitive 3,5-Dichlorobenzene-1-Carbohydrazide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 3,5-Dichlorobenzene-1-Carbohydrazide in China?
As a trusted 3,5-Dichlorobenzene-1-Carbohydrazide manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3,5-Dichlorobenzene-1-Carbohydrazide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 3,5-dichlorobenzoyl hydrazide?
3,5-Benzyl dihydroxybenzoate is an important organic compound that has a wide range of uses in many fields.
In the field of medicine, it has significant pharmacological activity. It can be used as an antioxidant, which can effectively scavenge free radicals in the body, slow down oxidative damage to cells, and then have positive significance for the prevention of many chronic diseases, such as cardiovascular diseases, neurodegenerative diseases, etc. And its anti-inflammatory properties should not be underestimated, which can reduce inflammation or provide help for the treatment of inflammation-related diseases.
In the chemical industry, it is often used as a key intermediate in organic synthesis. Through a series of chemical reactions, it can be converted into compounds with more complex structures and diverse functions, such as the preparation of polymer materials with specific structures, which endow the materials with unique properties, such as good stability and corrosion resistance.
In the field of fragrances, benzyl 3,5-dihydroxybenzoate can emit a unique aroma, so it is often used to prepare various flavors and fragrances to add a pleasant flavor to the product, improve the quality and attractiveness of the product, and is widely used in perfumes, cosmetics, detergents and other products.
In addition, in the food industry, due to its antioxidant properties, it can be used as a food preservative to delay the oxidative deterioration of food, extend the shelf life of food, and protect the color, flavor and nutritional content of food.
In the field of medicine, it has significant pharmacological activity. It can be used as an antioxidant, which can effectively scavenge free radicals in the body, slow down oxidative damage to cells, and then have positive significance for the prevention of many chronic diseases, such as cardiovascular diseases, neurodegenerative diseases, etc. And its anti-inflammatory properties should not be underestimated, which can reduce inflammation or provide help for the treatment of inflammation-related diseases.
In the chemical industry, it is often used as a key intermediate in organic synthesis. Through a series of chemical reactions, it can be converted into compounds with more complex structures and diverse functions, such as the preparation of polymer materials with specific structures, which endow the materials with unique properties, such as good stability and corrosion resistance.
In the field of fragrances, benzyl 3,5-dihydroxybenzoate can emit a unique aroma, so it is often used to prepare various flavors and fragrances to add a pleasant flavor to the product, improve the quality and attractiveness of the product, and is widely used in perfumes, cosmetics, detergents and other products.
In addition, in the food industry, due to its antioxidant properties, it can be used as a food preservative to delay the oxidative deterioration of food, extend the shelf life of food, and protect the color, flavor and nutritional content of food.
What are the chemical properties of 3,5-dichlorobenzoyl hydrazide?
Hydrazine 3,5-difluorophenylacetate is an organic compound with many chemical properties, as detailed below:
Acidic-basic
- Its molecule contains a hydrazine group (-NHNH ²), which is alkaline to a certain extent. Because there are lone pairs of electrons on the nitrogen atom, it can bind protons (H 🥰). In acidic solutions, it can interact with protons to form positively charged ions. In the case of hydrochloric acid, the hydrazine nitrogen atom will combine with the hydrogen ion in hydrochloric acid to form the corresponding salt.
- However, the molecule also has a benzene ring and a carboxyl group-derived structure. Although the acidity of the carboxyl group is weakened after the hydrazine group is formed, under certain conditions, the substituent group on the benzene ring and the entire conjugate system will affect the distribution of the electron cloud,
Redox
- Hydrazine groups are highly reducible. Nitrogen atoms are in a lower oxidation state and are easily oxidized. In case of strong oxidants, such as potassium permanganate (KMnO), etc., hydrazine-based nitrogen atoms will be oxidized, and the oxidation products will change according to the reaction conditions, or form nitrogen (N2), or form compounds containing higher valence nitrogen, such as nitrous acid derivatives.
- On the other hand, if the compound encounters a suitable reducing agent, the fluorine atoms on the benzene ring are relatively stable, but under certain strong reduction conditions, reductive defluorination reactions may occur, but this reaction usually requires specific catalysts and harsh reaction conditions.
Nucleophilicity and Electrophilicity
-The nitrogen atom of the hydrazine group is rich in electrons and has nucleophilicity. It can attack electrophilic reagents. In case of halogenated hydrocarbons, the hydrazine nitrogen atom will attack the carbon atom connected to the halogen in the halogenated hydrocarbons. The halogen leaves as a leaving group, and a nucleophilic substitution reaction occurs to generate new nitrogen-containing derivatives. The
-benzene ring has a certain nucleophilicity due to the conjugated π electronic system. It can react with strong electrophilic reagents, such as the Fu-Gram acylation reaction with the acyl halogen catalyzed by Lewis acid, to introduce acyl groups on the phenyl ring. The fluorine atom on the benzene ring will reduce the electron cloud density of the benzene ring due to its large electronegativity, which affects the nucleophilic reaction activity of the benzene ring to a certain extent.
-Carbonyl (C = O) carbons in the molecule are electrophilic. Due to the large electronegativity of oxygen atoms, carbonyl carbons are partially positively charged, which can attract nucleophilic reagents to attack and undergo nucleophilic addition reactions. For example, under acid catalysis with alcohols, acetals or hemiacetals are formed.
Substitution Reaction
-Substitution Reaction of hydrogen atoms on the benzene ring can occur. Although the electron cloud density of the benzene ring is reduced due to the fluorine atom being an ortho-para-locus group, the electrophilic substitution reaction still mainly occurs in the ortho and para-sites of the fluorine atom For example, when nitration is carried out, the nitro group (-NO ²) mainly enters the ortho and para-position of the fluorine atom to form the corresponding nitro substitution product. The hydrogen atom on the
-hydrazine group can also be replaced by other groups. If reacted with acid chloride, the acyl group will replace the hydrogen atom on the hydrazine group to form hydrazide compounds. Such reactions are often used in organic synthesis to construct nitrogen-containing heterocycles or introduce specific functional groups.
Acidic-basic
- Its molecule contains a hydrazine group (-NHNH ²), which is alkaline to a certain extent. Because there are lone pairs of electrons on the nitrogen atom, it can bind protons (H 🥰). In acidic solutions, it can interact with protons to form positively charged ions. In the case of hydrochloric acid, the hydrazine nitrogen atom will combine with the hydrogen ion in hydrochloric acid to form the corresponding salt.
- However, the molecule also has a benzene ring and a carboxyl group-derived structure. Although the acidity of the carboxyl group is weakened after the hydrazine group is formed, under certain conditions, the substituent group on the benzene ring and the entire conjugate system will affect the distribution of the electron cloud,
Redox
- Hydrazine groups are highly reducible. Nitrogen atoms are in a lower oxidation state and are easily oxidized. In case of strong oxidants, such as potassium permanganate (KMnO), etc., hydrazine-based nitrogen atoms will be oxidized, and the oxidation products will change according to the reaction conditions, or form nitrogen (N2), or form compounds containing higher valence nitrogen, such as nitrous acid derivatives.
- On the other hand, if the compound encounters a suitable reducing agent, the fluorine atoms on the benzene ring are relatively stable, but under certain strong reduction conditions, reductive defluorination reactions may occur, but this reaction usually requires specific catalysts and harsh reaction conditions.
Nucleophilicity and Electrophilicity
-The nitrogen atom of the hydrazine group is rich in electrons and has nucleophilicity. It can attack electrophilic reagents. In case of halogenated hydrocarbons, the hydrazine nitrogen atom will attack the carbon atom connected to the halogen in the halogenated hydrocarbons. The halogen leaves as a leaving group, and a nucleophilic substitution reaction occurs to generate new nitrogen-containing derivatives. The
-benzene ring has a certain nucleophilicity due to the conjugated π electronic system. It can react with strong electrophilic reagents, such as the Fu-Gram acylation reaction with the acyl halogen catalyzed by Lewis acid, to introduce acyl groups on the phenyl ring. The fluorine atom on the benzene ring will reduce the electron cloud density of the benzene ring due to its large electronegativity, which affects the nucleophilic reaction activity of the benzene ring to a certain extent.
-Carbonyl (C = O) carbons in the molecule are electrophilic. Due to the large electronegativity of oxygen atoms, carbonyl carbons are partially positively charged, which can attract nucleophilic reagents to attack and undergo nucleophilic addition reactions. For example, under acid catalysis with alcohols, acetals or hemiacetals are formed.
Substitution Reaction
-Substitution Reaction of hydrogen atoms on the benzene ring can occur. Although the electron cloud density of the benzene ring is reduced due to the fluorine atom being an ortho-para-locus group, the electrophilic substitution reaction still mainly occurs in the ortho and para-sites of the fluorine atom For example, when nitration is carried out, the nitro group (-NO ²) mainly enters the ortho and para-position of the fluorine atom to form the corresponding nitro substitution product. The hydrogen atom on the
-hydrazine group can also be replaced by other groups. If reacted with acid chloride, the acyl group will replace the hydrogen atom on the hydrazine group to form hydrazide compounds. Such reactions are often used in organic synthesis to construct nitrogen-containing heterocycles or introduce specific functional groups.
What is the synthesis method of 3,5-dichlorobenzoyl hydrazide?
The synthesis of 3,5-ethyl dihydroxybenzoate can be carried out according to the following steps.
First, an appropriate amount of resorcinol is taken as the starting material and placed in a clean reaction vessel. The resorcinol is active and is a key starting material for the reaction.
Then, an appropriate amount of diethyl malonate is added. Diethyl malonate plays an important role in the reaction, and its interaction with resorcinol lays the basic structure of the product. In this process, the ratio of the two needs to be precisely controlled, and the proportion is related to the reaction effect and product purity.
Then, a suitable catalyst is added. The choice of catalyst is very important, as it can effectively promote the progress of the reaction, accelerate the reaction rate, and enable the reaction to occur smoothly under relatively mild conditions. Common catalysts such as anhydrous zinc chloride can play a role in this reaction.
The reaction is carried out under suitable temperature and pressure conditions. Temperature regulation is extremely critical, and either too high or too low may affect the reaction process and product formation. Generally speaking, the reaction system is heated to a certain extent and maintained stable, so that the reactants can fully react.
During the reaction, it is necessary to pay close attention to the phenomenon and process of the reaction. By means such as thin layer chromatography, the degree of reaction can be monitored in real time to determine whether the reaction is completed.
After the reaction is completed, the reaction product is post-processed. This step aims to separate and purify the product and remove impurities. Extraction can be used first, and the product can be extracted from the reaction mixture with a suitable extractant. After that, through distillation, recrystallization and other operations, the purity of the product is further improved, and the final product is pure 3,5-dihydroxybenzoate. In this way, the synthesis of 3,5-dihydroxybenzoate can be achieved through various steps.
First, an appropriate amount of resorcinol is taken as the starting material and placed in a clean reaction vessel. The resorcinol is active and is a key starting material for the reaction.
Then, an appropriate amount of diethyl malonate is added. Diethyl malonate plays an important role in the reaction, and its interaction with resorcinol lays the basic structure of the product. In this process, the ratio of the two needs to be precisely controlled, and the proportion is related to the reaction effect and product purity.
Then, a suitable catalyst is added. The choice of catalyst is very important, as it can effectively promote the progress of the reaction, accelerate the reaction rate, and enable the reaction to occur smoothly under relatively mild conditions. Common catalysts such as anhydrous zinc chloride can play a role in this reaction.
The reaction is carried out under suitable temperature and pressure conditions. Temperature regulation is extremely critical, and either too high or too low may affect the reaction process and product formation. Generally speaking, the reaction system is heated to a certain extent and maintained stable, so that the reactants can fully react.
During the reaction, it is necessary to pay close attention to the phenomenon and process of the reaction. By means such as thin layer chromatography, the degree of reaction can be monitored in real time to determine whether the reaction is completed.
After the reaction is completed, the reaction product is post-processed. This step aims to separate and purify the product and remove impurities. Extraction can be used first, and the product can be extracted from the reaction mixture with a suitable extractant. After that, through distillation, recrystallization and other operations, the purity of the product is further improved, and the final product is pure 3,5-dihydroxybenzoate. In this way, the synthesis of 3,5-dihydroxybenzoate can be achieved through various steps.
What are the precautions for the storage and transportation of 3,5-dichlorobenzoyl hydrazide?
3% benzyl 2C5-dihydroxybenzoate should be carefully stored and transported.
First, this substance is quite sensitive to changes in temperature and humidity. If the temperature is too high, it may cause changes in its properties, and even cause chemical changes, which will damage the quality. Therefore, the storage place should be kept cool and dry. The temperature should be between 15 and 25 degrees Celsius, and the relative humidity should be controlled at 40% to 60%. If it is in a high temperature and humid place, it is necessary to set up proper temperature control and dehumidification equipment.
Second, because of its certain chemical activity, it is easy to react with certain substances. When storing, do not share with strong oxidizing agents, strong alkalis and other substances to prevent adverse reactions or even cause safety risks. During transportation, you should also pay attention to the properties of other goods in the cargo compartment to avoid mutual contamination and reaction.
Furthermore, this substance may have certain toxicity and irritation. Operators and handlers need to wear appropriate protective equipment, such as gloves, goggles, masks, etc., to prevent skin contact and respiratory inhalation. In case of accidental contact, rinse with plenty of water immediately, and seek medical attention in a timely manner according to the specific situation.
When transporting, the packaging must be solid and reliable. Standard packaging materials must be used to ensure that it will not be damaged and leaked during bumps and collisions. And the packaging should be clearly marked with warning labels and relevant information, so that transportation personnel and regulators can know its characteristics.
In short, in the storage and transportation of 3% 2C5-benzyl dihydroxybenzoate, it is necessary to exercise caution, pay attention to temperature and humidity, avoid mixed storage, take good protection, and ensure that the packaging is stable, so as to ensure its quality and transportation safety.
First, this substance is quite sensitive to changes in temperature and humidity. If the temperature is too high, it may cause changes in its properties, and even cause chemical changes, which will damage the quality. Therefore, the storage place should be kept cool and dry. The temperature should be between 15 and 25 degrees Celsius, and the relative humidity should be controlled at 40% to 60%. If it is in a high temperature and humid place, it is necessary to set up proper temperature control and dehumidification equipment.
Second, because of its certain chemical activity, it is easy to react with certain substances. When storing, do not share with strong oxidizing agents, strong alkalis and other substances to prevent adverse reactions or even cause safety risks. During transportation, you should also pay attention to the properties of other goods in the cargo compartment to avoid mutual contamination and reaction.
Furthermore, this substance may have certain toxicity and irritation. Operators and handlers need to wear appropriate protective equipment, such as gloves, goggles, masks, etc., to prevent skin contact and respiratory inhalation. In case of accidental contact, rinse with plenty of water immediately, and seek medical attention in a timely manner according to the specific situation.
When transporting, the packaging must be solid and reliable. Standard packaging materials must be used to ensure that it will not be damaged and leaked during bumps and collisions. And the packaging should be clearly marked with warning labels and relevant information, so that transportation personnel and regulators can know its characteristics.
In short, in the storage and transportation of 3% 2C5-benzyl dihydroxybenzoate, it is necessary to exercise caution, pay attention to temperature and humidity, avoid mixed storage, take good protection, and ensure that the packaging is stable, so as to ensure its quality and transportation safety.
What is the market price range for 3,5-dichlorobenzoyl hydrazide?
The market price range of 3,5-difluorobenzoyl chloride is difficult to determine. Its price often varies due to factors such as market conditions, supply and demand, quality and origin.
In the past, the market situation was stable, supply and demand were stable, and its price was between [X1] yuan and [X2] yuan per kilogram. At that time, there were many producers, materials were easy to obtain, the process was gradually maturing, and the cost was controllable, so the price was in this range.
When there are special occasions, such as lack of materials, or stricter environmental regulations, causing producers to reduce production, the price fluctuates violently. In short supply of materials, producers compete for purchases, and the price may soar to more than [X3] yuan per kilogram. As environmental protection becomes stricter, manufacturers need to invest heavily in environmental protection facilities, and the cost increases sharply, and the price also rises to about [X4] yuan per kilogram.
If demand suddenly increases, such as the pharmaceutical and pesticide industries, the demand for products containing this ingredient increases sharply, and the output is difficult to cope for a while, the price will also rise, up to [X5] yuan per kilogram.
To know the exact market price, it is advisable to consult the chemical product trading platform, manufacturer or distributor, who can tell the price according to the current situation.
In the past, the market situation was stable, supply and demand were stable, and its price was between [X1] yuan and [X2] yuan per kilogram. At that time, there were many producers, materials were easy to obtain, the process was gradually maturing, and the cost was controllable, so the price was in this range.
When there are special occasions, such as lack of materials, or stricter environmental regulations, causing producers to reduce production, the price fluctuates violently. In short supply of materials, producers compete for purchases, and the price may soar to more than [X3] yuan per kilogram. As environmental protection becomes stricter, manufacturers need to invest heavily in environmental protection facilities, and the cost increases sharply, and the price also rises to about [X4] yuan per kilogram.
If demand suddenly increases, such as the pharmaceutical and pesticide industries, the demand for products containing this ingredient increases sharply, and the output is difficult to cope for a while, the price will also rise, up to [X5] yuan per kilogram.
To know the exact market price, it is advisable to consult the chemical product trading platform, manufacturer or distributor, who can tell the price according to the current situation.
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