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3,5-Dichlorobenzene-1-Sulfonyl Chloride
|
HS Code |
636697 |
| Chemical Formula | C6H3Cl3O2S |
| Molecular Weight | 245.51 |
| Appearance | Typically a solid (physical state can vary based on conditions) |
| Odor | Pungent, characteristic of sulfonyl chloride compounds |
| Melting Point | Data varies in literature but around [specific value if known] °C |
| Boiling Point | Data varies in literature but around [specific value if known] °C |
| Solubility In Water | Insoluble or very slightly soluble (sulfonyl chlorides react with water) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Density | Data varies in literature but around [specific value if known] g/cm³ |
| Hazard Class | Corrosive, can cause burns to skin, eyes, and respiratory tract |
As an accredited 3,5-Dichlorobenzene-1-Sulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 3,5 - dichlorobenzene - 1 - sulfonyl chloride in sealed chemical - grade packaging. |
| Storage | 3,5 - dichlorobenzene - 1 - sulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It must be kept in a tightly - sealed container to prevent moisture ingress, as it may react with water. Store it separately from incompatible substances like bases and reducing agents to avoid chemical reactions. |
| Shipping | 3,5 - dichlorobenzene - 1 - sulfonyl chloride is a chemical. Ship it in well - sealed, corrosion - resistant containers. Follow proper hazardous materials shipping regulations to ensure safe transport and prevent leakage and environmental risks. |
Competitive 3,5-Dichlorobenzene-1-Sulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
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What are the main uses of 3,5-dichlorobenzene-1-sulfonyl chloride?
3,2,5-difluorobenzene-1-sulfonyl fluoride is a crucial chemical raw material in the field of organic synthesis, and its use is quite extensive.
The primary use is in the field of pharmaceutical synthesis. With its unique chemical structure, it can be used as a key intermediate to participate in the construction of many drug molecules. Taking some anti-cancer drugs as an example, in the synthesis process, 3,2,5-difluorobenzene-1-sulfonyl fluoride can introduce specific functional groups, endow the drug with precise biological activity, help to improve the targeting and inhibitory effect of the drug on cancer cells, and then provide strong support for the research and development of cancer therapeutic drugs.
In the field of pesticides, it also plays an important role. It can be used to synthesize high-efficiency, low-toxicity and environmentally friendly pesticides. Due to the excellent stability and biological activity of fluorinated organic compounds, pesticides made from 3,2,5-difluorobenzene-1-sulfonyl fluoride have strong effects on pests and stomach toxicity. It can effectively prevent and control crop pests, ensure crop yield and quality, and reduce adverse effects on the environment.
In addition, in the field of materials science, 3,2,5-difluorobenzene-1-sulfonyl fluoride also shows potential application value. It can be used to prepare special functional materials, such as polymer materials with special optical and electrical properties. By introducing its structural units into polymers, materials can be endowed with unique properties, such as improved solubility, thermal stability and mechanical properties of materials, so as to meet the needs of high-performance materials in different fields.
In summary, 3,2,5-difluorobenzene-1-sulfonyl fluoride occupies an indispensable position in many fields such as medicine, pesticides and materials science, and is of great significance to promote the development of related industries.
The primary use is in the field of pharmaceutical synthesis. With its unique chemical structure, it can be used as a key intermediate to participate in the construction of many drug molecules. Taking some anti-cancer drugs as an example, in the synthesis process, 3,2,5-difluorobenzene-1-sulfonyl fluoride can introduce specific functional groups, endow the drug with precise biological activity, help to improve the targeting and inhibitory effect of the drug on cancer cells, and then provide strong support for the research and development of cancer therapeutic drugs.
In the field of pesticides, it also plays an important role. It can be used to synthesize high-efficiency, low-toxicity and environmentally friendly pesticides. Due to the excellent stability and biological activity of fluorinated organic compounds, pesticides made from 3,2,5-difluorobenzene-1-sulfonyl fluoride have strong effects on pests and stomach toxicity. It can effectively prevent and control crop pests, ensure crop yield and quality, and reduce adverse effects on the environment.
In addition, in the field of materials science, 3,2,5-difluorobenzene-1-sulfonyl fluoride also shows potential application value. It can be used to prepare special functional materials, such as polymer materials with special optical and electrical properties. By introducing its structural units into polymers, materials can be endowed with unique properties, such as improved solubility, thermal stability and mechanical properties of materials, so as to meet the needs of high-performance materials in different fields.
In summary, 3,2,5-difluorobenzene-1-sulfonyl fluoride occupies an indispensable position in many fields such as medicine, pesticides and materials science, and is of great significance to promote the development of related industries.
What are the physical properties of 3,5-dichlorobenzene-1-sulfonyl chloride?
3,5-Dihydroxy-1-sulfobenzoic acid, this substance has unique physical properties. Its properties are mostly white to light yellow crystalline powder, which is quite stable in conventional environments.
Its solubility is easy to dissolve in water, which makes it well dispersed and dissolved in many aqueous systems, laying the foundation for its reaction or application in aqueous solutions. In organic solvents, such as ethanol, acetone, etc., it has a certain solubility, but the solubility is lower than that of water. This solubility property allows it to have more flexibility in the selection of different solvent systems, and the suitable solvent can be selected according to specific needs and reaction conditions.
When it comes to the melting point, it is between 250 and 260 degrees Celsius. This melting point reflects the strength of the intermolecular forces. A higher melting point means that the molecules are closely bound. When the temperature reaches the melting point, the molecule gains enough energy to overcome the interaction force and transform from a solid state to a liquid state.
Its density is about 1.7 to 1.8 g/cm ³. This density indicates that it has a larger mass per unit volume and is heavier than some low-density substances at the same volume. This property is crucial in scenarios involving mass to volume conversion, or in scenarios where the packing density of a substance needs to be considered.
In addition, 3,5-dihydroxy-1-sulfobenzoic acid is chemically stable at room temperature and pressure, but when it encounters strong acids and bases, due to the hydroxyl and sulfonic acid groups in its molecules, corresponding chemical reactions will occur, resulting in changes in structure and properties. Knowing these physical properties is of great significance for its storage, transportation and application in various fields.
Its solubility is easy to dissolve in water, which makes it well dispersed and dissolved in many aqueous systems, laying the foundation for its reaction or application in aqueous solutions. In organic solvents, such as ethanol, acetone, etc., it has a certain solubility, but the solubility is lower than that of water. This solubility property allows it to have more flexibility in the selection of different solvent systems, and the suitable solvent can be selected according to specific needs and reaction conditions.
When it comes to the melting point, it is between 250 and 260 degrees Celsius. This melting point reflects the strength of the intermolecular forces. A higher melting point means that the molecules are closely bound. When the temperature reaches the melting point, the molecule gains enough energy to overcome the interaction force and transform from a solid state to a liquid state.
Its density is about 1.7 to 1.8 g/cm ³. This density indicates that it has a larger mass per unit volume and is heavier than some low-density substances at the same volume. This property is crucial in scenarios involving mass to volume conversion, or in scenarios where the packing density of a substance needs to be considered.
In addition, 3,5-dihydroxy-1-sulfobenzoic acid is chemically stable at room temperature and pressure, but when it encounters strong acids and bases, due to the hydroxyl and sulfonic acid groups in its molecules, corresponding chemical reactions will occur, resulting in changes in structure and properties. Knowing these physical properties is of great significance for its storage, transportation and application in various fields.
What are the chemical properties of 3,5-dichlorobenzene-1-sulfonyl chloride?
3,5-Difluorobenzene-1-sulfonyl fluoride is an organic compound with unique chemical properties. Its chemical activity is high, the electronegativity of fluorine atoms is large, the bond energy of C-F is large, and the compound stability is strong. Due to the presence of sulfonyl fluoride groups (-SO 2O F), many chemical reactions can occur.
First, nucleophilic substitution reaction. Sulfonyl fluoride sulfur atoms are electrophilic and vulnerable to attack by nucleophilic reagents. Fluoride ions leave to cause nucleophilic reagents to replace sulfonyl fluoride groups to form new organic compounds. This property makes 3,5-difluorobenzene-1-sulfonyl fluoride a key intermediate in the field of organic synthesis for the preparation of various sulfur-containing organic compounds.
Second, hydrolysis reaction. Under specific conditions, especially alkali catalysis, 3,5-difluorobenzene-1-sulfonyl fluoride can react with water, and the sulfonyl fluoride group can be hydrolyzed to form a sulfonic acid group (-SO 🥰 H). This reaction is commonly used in the preparation of sulfonic acid-containing compounds or the introduction of sulfonic acid groups to specific substrates.
Third, react with metal-organic reagents. It can react with metal-organic reagents such as Grignard reagent and organolithium reagent. Through nucleophilic addition or substitution process, carbon-sulfur bonds or other chemical bonds are formed, and the molecular structure is expanded to provide an effective path for the synthesis of complex organic molecules.
Fourth, participate in the polymerization reaction. If the molecular structure is suitable, 3,5-difluorobenzene-1-sulfonyl fluoride can participate in the polymerization reaction as a monomer or crosslinking agent, and fluorine-containing and sulfonyl-based structural units are introduced to endow the polymer with special properties, such as improving the thermal stability, chemical stability and surface properties of the polymer.
In summary, 3,5-difluorobenzene-1-sulfonyl fluoride is widely used in the fields of organic synthesis and materials science due to its diverse chemical properties, which can lay the foundation for the creation of novel functional materials and organic compounds.
First, nucleophilic substitution reaction. Sulfonyl fluoride sulfur atoms are electrophilic and vulnerable to attack by nucleophilic reagents. Fluoride ions leave to cause nucleophilic reagents to replace sulfonyl fluoride groups to form new organic compounds. This property makes 3,5-difluorobenzene-1-sulfonyl fluoride a key intermediate in the field of organic synthesis for the preparation of various sulfur-containing organic compounds.
Second, hydrolysis reaction. Under specific conditions, especially alkali catalysis, 3,5-difluorobenzene-1-sulfonyl fluoride can react with water, and the sulfonyl fluoride group can be hydrolyzed to form a sulfonic acid group (-SO 🥰 H). This reaction is commonly used in the preparation of sulfonic acid-containing compounds or the introduction of sulfonic acid groups to specific substrates.
Third, react with metal-organic reagents. It can react with metal-organic reagents such as Grignard reagent and organolithium reagent. Through nucleophilic addition or substitution process, carbon-sulfur bonds or other chemical bonds are formed, and the molecular structure is expanded to provide an effective path for the synthesis of complex organic molecules.
Fourth, participate in the polymerization reaction. If the molecular structure is suitable, 3,5-difluorobenzene-1-sulfonyl fluoride can participate in the polymerization reaction as a monomer or crosslinking agent, and fluorine-containing and sulfonyl-based structural units are introduced to endow the polymer with special properties, such as improving the thermal stability, chemical stability and surface properties of the polymer.
In summary, 3,5-difluorobenzene-1-sulfonyl fluoride is widely used in the fields of organic synthesis and materials science due to its diverse chemical properties, which can lay the foundation for the creation of novel functional materials and organic compounds.
What is the production method of 3,5-dichlorobenzene-1-sulfonyl chloride?
The preparation method of 3,5-dihydroxy-1-tert-butyl methyl ether is to take an appropriate amount of starting materials and undergo a multi-step delicate chemical reaction.
In the first step, a compound containing a specific functional group is selected, based on it, and specific reagents and catalysts are added under suitable reaction conditions. The reaction needs to be carried out under precisely controlled temperature, pressure and reaction time. The control of temperature is particularly critical. Too high or too low can cause reaction deviation, resulting in impurity or low yield of the product. Usually, the reaction temperature in this step is maintained within a certain range, so that the reaction can be advanced in an orderly manner.
In the second step, the first reaction product needs to be carefully separated and purified. This process uses techniques such as distillation, extraction, and recrystallization to remove impurities and obtain a purer intermediate product. This intermediate product is the key raw material for subsequent reactions, and its purity is directly related to the quality of the final product.
Furthermore, the purified intermediate product is added to the new reaction system with different reagents and conditions to further transform it. This step of the reaction aims to build the specific structure of the target product, so that each atom is connected to the functional group in the desired way.
In the last step, after the separation and purification process again, it is detected by high performance liquid chromatography, mass spectrometry and other means to ensure that the obtained product is 3,5-dihydroxy-1-tert-butyl methyl ether, and the purity is up to standard. This preparation method requires strict control of the reaction in each step and attention to detail to obtain the target product stably and efficiently.
In the first step, a compound containing a specific functional group is selected, based on it, and specific reagents and catalysts are added under suitable reaction conditions. The reaction needs to be carried out under precisely controlled temperature, pressure and reaction time. The control of temperature is particularly critical. Too high or too low can cause reaction deviation, resulting in impurity or low yield of the product. Usually, the reaction temperature in this step is maintained within a certain range, so that the reaction can be advanced in an orderly manner.
In the second step, the first reaction product needs to be carefully separated and purified. This process uses techniques such as distillation, extraction, and recrystallization to remove impurities and obtain a purer intermediate product. This intermediate product is the key raw material for subsequent reactions, and its purity is directly related to the quality of the final product.
Furthermore, the purified intermediate product is added to the new reaction system with different reagents and conditions to further transform it. This step of the reaction aims to build the specific structure of the target product, so that each atom is connected to the functional group in the desired way.
In the last step, after the separation and purification process again, it is detected by high performance liquid chromatography, mass spectrometry and other means to ensure that the obtained product is 3,5-dihydroxy-1-tert-butyl methyl ether, and the purity is up to standard. This preparation method requires strict control of the reaction in each step and attention to detail to obtain the target product stably and efficiently.
What are the precautions for the use of 3,5-dichlorobenzene-1-sulfonyl chloride?
3,5-Difluorobenzene-1-sulfonyl fluoride is a rather special chemical substance, and many things must be paid attention to when using it.
First, safety protection must be comprehensive. This substance is toxic and corrosive to a certain extent, touching the human body, or causing skin burns and eye damage. Therefore, when using, protective equipment must be indispensable, such as protective clothing, protective gloves, protective glasses, etc., to prevent accidents. And the operation should be carried out in a well-ventilated place, preferably in a fume hood, so that the volatile harmful gases can be dissipated in time to avoid inhalation and harm to health.
Second, storage also needs to be cautious. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, and away from direct sunlight. Because of its active chemical nature, it can react violently with water or moisture, so the drying of the storage environment is extremely critical. At the same time, it should be stored separately from oxidizing agents and alkalis, and must not be mixed to prevent dangerous chemical reactions.
Third, the operation of access should be precise and meticulous. Use suitable utensils for measurement and transfer to avoid spillage. If it is accidentally spilled, take corresponding emergency treatment measures immediately. When a small amount is spilled, it can be mixed with sand, dry lime or soda ash and collected in a dry, clean and covered container. When a large amount is spilled, build an embankment or dig a pit to contain it, transfer it to a tanker or special collector with a pump, and recycle or transport it to a waste disposal site for disposal.
Fourth, know the emergency disposal method. If the skin is accidentally touched, quickly remove the contaminated clothing, rinse with a large amount of flowing water for at least 15 minutes, and then seek medical attention. If eye contact, immediately lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes, and seek medical attention as soon as possible. If inhaled, quickly leave the scene to a fresh air place, keep the respiratory tract unobstructed, such as breathing difficulties, give oxygen, if breathing stops, immediately perform artificial respiration, and seek medical attention.
First, safety protection must be comprehensive. This substance is toxic and corrosive to a certain extent, touching the human body, or causing skin burns and eye damage. Therefore, when using, protective equipment must be indispensable, such as protective clothing, protective gloves, protective glasses, etc., to prevent accidents. And the operation should be carried out in a well-ventilated place, preferably in a fume hood, so that the volatile harmful gases can be dissipated in time to avoid inhalation and harm to health.
Second, storage also needs to be cautious. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, and away from direct sunlight. Because of its active chemical nature, it can react violently with water or moisture, so the drying of the storage environment is extremely critical. At the same time, it should be stored separately from oxidizing agents and alkalis, and must not be mixed to prevent dangerous chemical reactions.
Third, the operation of access should be precise and meticulous. Use suitable utensils for measurement and transfer to avoid spillage. If it is accidentally spilled, take corresponding emergency treatment measures immediately. When a small amount is spilled, it can be mixed with sand, dry lime or soda ash and collected in a dry, clean and covered container. When a large amount is spilled, build an embankment or dig a pit to contain it, transfer it to a tanker or special collector with a pump, and recycle or transport it to a waste disposal site for disposal.
Fourth, know the emergency disposal method. If the skin is accidentally touched, quickly remove the contaminated clothing, rinse with a large amount of flowing water for at least 15 minutes, and then seek medical attention. If eye contact, immediately lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes, and seek medical attention as soon as possible. If inhaled, quickly leave the scene to a fresh air place, keep the respiratory tract unobstructed, such as breathing difficulties, give oxygen, if breathing stops, immediately perform artificial respiration, and seek medical attention.
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