Linshang Chemical
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3,5-Dichlorobenzeneboronic Acid
Linshang Chemical
|
HS Code |
290796 |
| Chemical Formula | C6H3BCl2O2 |
| Molar Mass | 190.81 g/mol |
| Appearance | White to off - white solid |
| Solubility In Water | Slightly soluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, toluene |
| Melting Point | 125 - 129 °C |
| Pka | Around 8 - 9 (approximate value for boronic acid group) |
| Density | N/A (solid, density less relevant in common use) |
| Stability | Stable under normal conditions, but sensitive to moisture and strong bases |
As an accredited 3,5-Dichlorobenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 3,5 - dichlorobenzeneboronic Acid in a sealed, chemical - resistant plastic bag. |
| Storage | 3,5 - dichlorobenzeneboronic acid should be stored in a cool, dry, well - ventilated area, away from heat sources and direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and contact with air, which could lead to degradation. Store separately from incompatible substances like strong oxidizing agents and bases to avoid potential reactions. |
| Shipping | 3,5 - dichlorobenzeneboronic acid is shipped in well - sealed containers, often within sturdy packaging. Special care is taken to prevent breakage and exposure, following strict regulations for transporting chemical substances. |
Competitive 3,5-Dichlorobenzeneboronic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 3,5-Dichlorobenzeneboronic Acid in China?
As a trusted 3,5-Dichlorobenzeneboronic Acid manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3,5-Dichlorobenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main application fields of 3,5-dichlorophenylboronic acid
3,5-Dihydroxybenzoic acid is widely used and has important applications in medicine, chemical industry, food and other fields.
In the field of medicine, this substance has significant medicinal value. It can be used as a key intermediate in drug synthesis to prepare drugs with antibacterial and anti-inflammatory effects. Because it has a specific chemical structure, it can interact with bacteria or inflammation-related targets, thereby inhibiting bacterial growth and reducing inflammatory reactions. For example, in some external drugs for treating skin inflammation, it contains active ingredients synthesized from this raw material to help relieve skin redness, swelling, itching and other uncomfortable symptoms.
In the chemical industry, 3,5-Dihydroxybenzoic acid can be used as a monomer for synthesizing special polymer materials. By polymerizing with other compounds, polymers with unique properties can be generated, such as high temperature and corrosion-resistant engineering plastics. These polymer materials are indispensable in high-end industrial fields such as aerospace and automobile manufacturing, and can meet the strict requirements of material properties in extreme environments. In addition, in the coating industry, it can also play a role in improving the adhesion, durability and other properties of coatings, so that coatings can better protect the surface of the coated object.
In the food field, 3,5-dihydroxybenzoic acid can act as a food preservative. Because it has certain antibacterial ability, it can inhibit the growth and reproduction of microorganisms in food, effectively prolong the shelf life of food, and ensure food safety. At the same time, compared with some chemical synthetic preservatives, it is relatively safe, less harmful to human health, and meets the needs of modern consumers for natural and safe food additives, so it is widely used in the food industry.
In the field of medicine, this substance has significant medicinal value. It can be used as a key intermediate in drug synthesis to prepare drugs with antibacterial and anti-inflammatory effects. Because it has a specific chemical structure, it can interact with bacteria or inflammation-related targets, thereby inhibiting bacterial growth and reducing inflammatory reactions. For example, in some external drugs for treating skin inflammation, it contains active ingredients synthesized from this raw material to help relieve skin redness, swelling, itching and other uncomfortable symptoms.
In the chemical industry, 3,5-Dihydroxybenzoic acid can be used as a monomer for synthesizing special polymer materials. By polymerizing with other compounds, polymers with unique properties can be generated, such as high temperature and corrosion-resistant engineering plastics. These polymer materials are indispensable in high-end industrial fields such as aerospace and automobile manufacturing, and can meet the strict requirements of material properties in extreme environments. In addition, in the coating industry, it can also play a role in improving the adhesion, durability and other properties of coatings, so that coatings can better protect the surface of the coated object.
In the food field, 3,5-dihydroxybenzoic acid can act as a food preservative. Because it has certain antibacterial ability, it can inhibit the growth and reproduction of microorganisms in food, effectively prolong the shelf life of food, and ensure food safety. At the same time, compared with some chemical synthetic preservatives, it is relatively safe, less harmful to human health, and meets the needs of modern consumers for natural and safe food additives, so it is widely used in the food industry.
What are the synthesis methods of 3,5-dichlorophenylboronic acid?
The synthesis method of 3,5-dihydroxybenzoic acid is not detailed in ancient books, but now it can be found according to the principles of modern chemistry.
First, resorcinol is used as the starting material, and formyl groups can be introduced through formylation. The formylation method often uses phosphorus oxychloride and N, N-dimethylformamide as a reagent, and reacts at a suitable temperature to introduce one of the hydroxy orthos of resorcinol into the formyl group to obtain 2-formylresorcinol. After oxidation, the formyl group can be converted into a carboxyl group. At the time of oxidation, a strong oxidant such as potassium permanganate can be used to react in an alkaline environment. After acidification, 3,5-dihydroxybenzoic acid can be obtained.
Second, isophthalic acid can also be used as a raw material. First, the carboxyl group of isophthalic acid is converted into a returnable group, such as esterification reaction with methanol catalyzed by concentrated sulfuric acid to obtain dimethyl isophthalate. Then a suitable reducing agent, such as sodium borohydride-aluminum trichloride system, selectively reduces one of the ester groups to a hydroxyl group to obtain 3-hydroxy-5-methoxybenzoate methyl ester. Subsequent hydrolysis reaction, hydrolysis of ester groups under acidic conditions to obtain 3-hydroxy-5-methoxybenzoic acid. Finally, through demethylation reaction, treatment with hydroiodic acid and other reagents to remove methoxy groups, 3,5-dihydroxybenzoic acid can be obtained.
Third, related precursors can also be extracted from natural products and then chemically modified. For example, some plants contain compounds with similar structures. After separation and purification, their functional groups can be chemically modified to achieve the purpose of synthesizing 3,5-dihydroxybenzoic acid. This approach requires detailed study of plant components, and the extraction and modification process requires fine operation to maintain the purity and yield of the product.
First, resorcinol is used as the starting material, and formyl groups can be introduced through formylation. The formylation method often uses phosphorus oxychloride and N, N-dimethylformamide as a reagent, and reacts at a suitable temperature to introduce one of the hydroxy orthos of resorcinol into the formyl group to obtain 2-formylresorcinol. After oxidation, the formyl group can be converted into a carboxyl group. At the time of oxidation, a strong oxidant such as potassium permanganate can be used to react in an alkaline environment. After acidification, 3,5-dihydroxybenzoic acid can be obtained.
Second, isophthalic acid can also be used as a raw material. First, the carboxyl group of isophthalic acid is converted into a returnable group, such as esterification reaction with methanol catalyzed by concentrated sulfuric acid to obtain dimethyl isophthalate. Then a suitable reducing agent, such as sodium borohydride-aluminum trichloride system, selectively reduces one of the ester groups to a hydroxyl group to obtain 3-hydroxy-5-methoxybenzoate methyl ester. Subsequent hydrolysis reaction, hydrolysis of ester groups under acidic conditions to obtain 3-hydroxy-5-methoxybenzoic acid. Finally, through demethylation reaction, treatment with hydroiodic acid and other reagents to remove methoxy groups, 3,5-dihydroxybenzoic acid can be obtained.
Third, related precursors can also be extracted from natural products and then chemically modified. For example, some plants contain compounds with similar structures. After separation and purification, their functional groups can be chemically modified to achieve the purpose of synthesizing 3,5-dihydroxybenzoic acid. This approach requires detailed study of plant components, and the extraction and modification process requires fine operation to maintain the purity and yield of the product.
What are the physical and chemical properties of 3,5-dichlorophenylboronic acid?
3,5-Dihydroxybenzoic acid is an organic compound. Its physical and chemical properties are unique and have important research and application value.
Looking at its physical properties, under normal conditions, 3,5-Dihydroxybenzoic acid is a white to light yellow crystalline powder, which makes it easy to identify. Its melting point is quite high, about 232-235 ° C. The characteristics of the melting point are the key indicators in the identification and separation and purification of substances. A higher melting point highlights the strong intermolecular force and relatively stable structure. In addition, its solubility is also an important physical property. Slightly soluble in cold water, but in hot water, ethanol, ether, acetone and other solvents, the solubility is good. This difference in solubility offers many possibilities for its extraction, separation and application in different solvent systems.
Discussing chemical properties, 3,5-dihydroxybenzoic acid contains two important functional groups: phenolic hydroxyl group and carboxyl group. The phenolic hydroxyl group is weakly acidic and can react with bases to form corresponding phenolic salts. Although this acidity is weak, it can participate in many acid-base reactions in specific chemical environments. At the same time, the phenolic hydroxyl group can be oxidized easily due to the conjugation effect of the benzene ring, the electron cloud density increases, and it can be oxidized when exposed to strong oxidants, resulting in structural changes. The carboxyl group has the properties of a typical carboxylic acid and can be esterified with alcohols to form ester compounds. This esterification reaction is an important way to prepare specific esters in the field of organic synthesis. In addition, due to the presence of benzene ring, 3,5-dihydroxybenzoic acid can undergo electrophilic substitution reaction, and halogenation, nitrification and other reactions can occur at specific positions on the benzene ring, providing a broad space for its structural modification and functional derivation.
In short, the physical and chemical properties of 3,5-dihydroxybenzoic acid endow it with potential application prospects in many fields such as medicine, chemical industry, and materials, which are worthy of further investigation.
Looking at its physical properties, under normal conditions, 3,5-Dihydroxybenzoic acid is a white to light yellow crystalline powder, which makes it easy to identify. Its melting point is quite high, about 232-235 ° C. The characteristics of the melting point are the key indicators in the identification and separation and purification of substances. A higher melting point highlights the strong intermolecular force and relatively stable structure. In addition, its solubility is also an important physical property. Slightly soluble in cold water, but in hot water, ethanol, ether, acetone and other solvents, the solubility is good. This difference in solubility offers many possibilities for its extraction, separation and application in different solvent systems.
Discussing chemical properties, 3,5-dihydroxybenzoic acid contains two important functional groups: phenolic hydroxyl group and carboxyl group. The phenolic hydroxyl group is weakly acidic and can react with bases to form corresponding phenolic salts. Although this acidity is weak, it can participate in many acid-base reactions in specific chemical environments. At the same time, the phenolic hydroxyl group can be oxidized easily due to the conjugation effect of the benzene ring, the electron cloud density increases, and it can be oxidized when exposed to strong oxidants, resulting in structural changes. The carboxyl group has the properties of a typical carboxylic acid and can be esterified with alcohols to form ester compounds. This esterification reaction is an important way to prepare specific esters in the field of organic synthesis. In addition, due to the presence of benzene ring, 3,5-dihydroxybenzoic acid can undergo electrophilic substitution reaction, and halogenation, nitrification and other reactions can occur at specific positions on the benzene ring, providing a broad space for its structural modification and functional derivation.
In short, the physical and chemical properties of 3,5-dihydroxybenzoic acid endow it with potential application prospects in many fields such as medicine, chemical industry, and materials, which are worthy of further investigation.
What are the precautions for 3,5-dichlorophenylboronic acid during storage and transportation?
For 3% 2C5-dihydroxybenzoic acid, many things should be paid attention to during storage and transportation.
When storing, the temperature and humidity of the environment are the first priority. This substance should be stored in a cool and dry place. Due to excessive temperature or humidity, it may cause its properties to change, or cause chemical reactions, which may damage its quality. If it is hot in the summer, it is easy to decompose at high temperature; if it is humid in a humid place, it is easy to cause it to agglomerate.
Furthermore, it is necessary to pay attention to the storage container. Appropriate materials should be selected to avoid reactions with the container. Glass containers are often preferred because of their stable chemical properties, so care should be taken to avoid damage. If it is stored in a plastic container, make sure that the plastic material does not interact with the substance to avoid contaminating the acid.
When transporting, safety is of paramount importance. This substance may have a certain chemical activity, and it should be prevented from violent vibration and collision during transportation to avoid package damage and material leakage. In case of leakage, it may cause harm to the safety of transporters and the surrounding environment.
At the same time, the temperature and humidity of the transportation environment cannot be ignored. If it is in a hot season, long-distance transportation needs to take cooling measures to prevent the temperature from affecting the stability of the material; when transporting in a humid area, moisture-proof work should be done to ensure that the packaging is tight.
And transportation needs to follow relevant regulations and standards, and be equipped with corresponding protective and emergency equipment. In the event of an accident on the way, effective measures can be taken quickly to reduce losses and hazards. In this way, 3% 2C5-Dihydroxybenzoic acid can be guaranteed to maintain its original properties and quality during storage and transportation.
When storing, the temperature and humidity of the environment are the first priority. This substance should be stored in a cool and dry place. Due to excessive temperature or humidity, it may cause its properties to change, or cause chemical reactions, which may damage its quality. If it is hot in the summer, it is easy to decompose at high temperature; if it is humid in a humid place, it is easy to cause it to agglomerate.
Furthermore, it is necessary to pay attention to the storage container. Appropriate materials should be selected to avoid reactions with the container. Glass containers are often preferred because of their stable chemical properties, so care should be taken to avoid damage. If it is stored in a plastic container, make sure that the plastic material does not interact with the substance to avoid contaminating the acid.
When transporting, safety is of paramount importance. This substance may have a certain chemical activity, and it should be prevented from violent vibration and collision during transportation to avoid package damage and material leakage. In case of leakage, it may cause harm to the safety of transporters and the surrounding environment.
At the same time, the temperature and humidity of the transportation environment cannot be ignored. If it is in a hot season, long-distance transportation needs to take cooling measures to prevent the temperature from affecting the stability of the material; when transporting in a humid area, moisture-proof work should be done to ensure that the packaging is tight.
And transportation needs to follow relevant regulations and standards, and be equipped with corresponding protective and emergency equipment. In the event of an accident on the way, effective measures can be taken quickly to reduce losses and hazards. In this way, 3% 2C5-Dihydroxybenzoic acid can be guaranteed to maintain its original properties and quality during storage and transportation.
What is the market price trend of 3,5-dichlorophenylboronic acid?
Recently, the price state of 3% 2C5-dihydroxybenzoic acid in the market has fluctuated from time to time. The change in its price is due to various reasons intertwined.
Looking at the supply and demand situation, if there are many people who want it, but the supply is small, the price will rise; on the contrary, if the supply in the market exceeds the demand, and the demand is few, the price will be lower. There was a time in the past when the demand for 3% 2C5-dihydroxybenzoic acid was quite high in various industries, and the demand for pharmaceutical, chemical and other industries was wide. However, the lack of production at that time caused the scarcity of this product in the market, and its price skyrocketed.
And the source and cost of raw materials also affect its price. The production of this acid requires specific raw materials. If the acquisition of raw materials is difficult, or the price increases due to weather or government decrees, etc., the production cost of 3% 2C5-dihydroxybenzoic acid will increase. Businesses will also increase prices to protect their profits. In the past, the raw material production area encountered disasters, the harvest of raw materials was greatly reduced, and its price soared. The market price of this acid also rose accordingly.
Furthermore, the competition in the same industry and the revolution in technology also have an impact on the price. Businesses compete, or cut prices to attract customers in order to occupy the market; if new technologies are released, which can reduce production costs and increase production rates, the supply of the market may change, and the price will also change accordingly. The price of this acid in the market gradually fell after tasting the new technology, which increased the production and decreased the cost.
Overall, the market price of 3% 2C5-dihydroxybenzoic acid often rises or falls due to supply and demand, raw materials, competition, and technical matters. When the industry assesses the situation and understands the reasons for its changes, it will be safe in the city.
Looking at the supply and demand situation, if there are many people who want it, but the supply is small, the price will rise; on the contrary, if the supply in the market exceeds the demand, and the demand is few, the price will be lower. There was a time in the past when the demand for 3% 2C5-dihydroxybenzoic acid was quite high in various industries, and the demand for pharmaceutical, chemical and other industries was wide. However, the lack of production at that time caused the scarcity of this product in the market, and its price skyrocketed.
And the source and cost of raw materials also affect its price. The production of this acid requires specific raw materials. If the acquisition of raw materials is difficult, or the price increases due to weather or government decrees, etc., the production cost of 3% 2C5-dihydroxybenzoic acid will increase. Businesses will also increase prices to protect their profits. In the past, the raw material production area encountered disasters, the harvest of raw materials was greatly reduced, and its price soared. The market price of this acid also rose accordingly.
Furthermore, the competition in the same industry and the revolution in technology also have an impact on the price. Businesses compete, or cut prices to attract customers in order to occupy the market; if new technologies are released, which can reduce production costs and increase production rates, the supply of the market may change, and the price will also change accordingly. The price of this acid in the market gradually fell after tasting the new technology, which increased the production and decreased the cost.
Overall, the market price of 3% 2C5-dihydroxybenzoic acid often rises or falls due to supply and demand, raw materials, competition, and technical matters. When the industry assesses the situation and understands the reasons for its changes, it will be safe in the city.
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