3,5-Dichlorobenzenesulfonamide
Linshang Chemical
HS Code |
312228 |
Chemical Formula | C6H3Cl2NO2S |
Molar Mass | 238.065 g/mol |
Appearance | Solid |
Melting Point | 148 - 150 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in some organic solvents like ethanol, acetone |
Boiling Point | N/A (decomposes before boiling) |
Odor | Odorless or very faint odor |
Ph | Neutral in nature |
As an accredited 3,5-Dichlorobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 3,5 - dichlorobenzenesulfonamide packaged in a sealed, chemical - resistant bag. |
Storage | 3,5 - dichlorobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and incompatible substances like strong oxidizing agents. Store it in a tightly closed container to prevent moisture absorption and potential degradation. Label the storage container clearly to ensure proper handling and safety. |
Shipping | 3,5 - dichlorobenzenesulfonamide should be shipped in well - sealed, corrosion - resistant containers. Ensure compliance with chemical transportation regulations. Ship at ambient temperature, avoiding exposure to heat, moisture, and incompatible substances. |
Competitive 3,5-Dichlorobenzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 3,5-Dichlorobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of ancient medicine, there may be traces. Ancient healers often used various herbs and golden stones to treat diseases. This dioxabicyclo [2.2.1] heptane, if its physical properties are mild and have specific pharmacology, can be used as a prescription for adjuvant, to help medicine power powder, or to reconcile various medicines. The medicines contained in the Compendium of Materia Medica have been repeatedly tried by predecessors to explore their properties and understand their uses. Although the name of dioxabicyclo [2.2.1] heptane is not seen, it is well-known in ancient recipes, or there are similar effects.
Furthermore, in ancient brewing techniques, or related. Ancient winemaking, pay attention to the right time and place, more emphasis on raw materials and fermentation methods. The fermentation process is delicate and complex, and various substances interact. This dioxabicyclo [2.2.1] heptane, if naturally generated in the fermentation environment, may affect the flavor and quality of the wine. Ancient wine is famous, its unique flavor may be related to the subtle effects of such unknown substances. Looking at the method of brewing recorded in "Qi Min Yaoshu", from material selection to craftsmanship, all strive for excellence, and dioxabicyclo [2.2.1] heptane may be quietly influenced in it.
Although ancient books do not describe its use in detail, they are extrapolated from the wisdom of ancient craftsmanship. It may have its potential value in many fields such as medicine and brewing, and it will be further explored by later generations to clarify its details.
1. ** Acidic **: This compound contains carboxyl groups (-COOH). Due to the high electronegativity of oxygen atoms in the carboxyl group, the hydrogen-oxygen bond electron cloud is biased towards oxygen, and hydrogen is easily dissociated in the form of protons, so it is acidic. In solution, it can react with bases to form corresponding carboxylic salts and water. For example, in reaction with sodium hydroxide: 3,5-dibromobenzoic acid + NaOH → 3,5-dibromobenzoic acid + H2O O. This reaction is often used in organic synthesis to separate and purify the compound, convert it into water-soluble salts by taking advantage of its acidity, separate it from other non-acidic organic compounds, and then acidify it to obtain the original compound.
2. ** Halogenated aromatic hydrocarbon properties **: There are two bromine atoms attached to the benzene ring, and the bromine atom is an ortho-para-site group. Although the electron cloud density of the benzene ring is reduced, the activity of the electrophilic substitution reaction of the benzene ring is slightly reduced, but because it is ortho-para-site, it can still guide the electrophilic reagent to attack the ortho-para-site of the benzene ring. For example, when nitrification occurs, the nitro group (-NO ²) mainly enters the ortho- However, since the carboxyl group is also a meta-localization group, and the blunt effect is stronger than that of the bromine atom, in the actual reaction, affected by the carboxyl group, the electrophilic substitution mainly occurs in the carboxyl group meta-site, and at the same time affected by the bromine atom to a certain extent, the reaction activity and substitution position are complicated.
3. ** Carboxyl-related reactions **:
- ** esterification reactions **: In a catalyst such as concentrated sulfuric acid and under heating conditions, the hydroxyl group in the carboxyl group of 3,5-dibromobenzoic acid can be esterified with the alcohol hydroxyl group to form an ester bond by dehydration. Take the reaction with ethanol as an example: 3,5-dibromobenzoic acid + C 2O H OH (concentrated sulfuric acid, heated) 3,5-dibromobenzoic acid ethyl ester + H 2O O. The resulting ester compounds are widely used in the fields of fragrances, coatings, etc.
- ** Acylation reaction **: It can react with acylating reagents such as acyl chloride and acid anhydride to transform carboxyl groups into acyl groups to form new acyl compounds. This reaction is a common method for constructing carbon-carbon bonds and carbon-hetero bonds in organic synthesis. It can introduce different functional groups and enrich the structure and properties of compounds.
First, salicylic acid is used as the starting material. First, salicylic acid and acetic anhydride are reacted under appropriate conditions to form acetylsalicylic acid. This reaction requires temperature control and time control to ensure sufficient reaction. Afterwards, acetylsalicylic acid is hydrolyzed in an alkaline environment to obtain 3,2,5-dihydroxybenzoic acid. In this process, the concentration of alkali, hydrolysis time and temperature are all key factors that affect the purity and yield of the product.
Second, resorcinol is used as the starting material. The carboxylation reaction of resorcinol and carbon dioxide occurs under specific catalyst and pressure and temperature conditions. This reaction condition is quite harsh, and the activity and selectivity of the catalyst are extremely high. After the reaction, the target product can be obtained through a series of separation and purification steps, such as extraction, crystallization, etc.
Third, the microbial fermentation method is used. Specific microbial strains are screened, and nutrients such as carbon sources and nitrogen sources are used as the medium. After the fermentation process, the enzyme system in the microorganism can catalyze the production of 3,2,5-dihydroxybenzoic acid from the substrate. This method is green and environmentally friendly, but the fermentation conditions are extremely fine-controlled, including temperature, pH value, dissolved oxygen, etc., and the subsequent product separation and purification is also difficult.
The various methods for preparing 3,2,5-dihydroxybenzoic acid have their own advantages and disadvantages. Although the chemical synthesis method is mature, some steps require the use of a large number of organic solvents and chemical reagents, which have a certain impact on the environment; although the microbial fermentation method is green, it faces complex fermentation conditions and product separation problems. In actual production, the appropriate method should be weighed according to specific needs and conditions.
The first priority is its application scenarios. This material is often used in absorbable sutures and tissue repair scaffolds. If it is used to make sutures, during surgery, physicians need to choose sutures containing this material reasonably according to the wound condition and healing expectations. If the wound is a high-tension part, such as near the joint, it is necessary to consider whether its strength can meet the tension requirements during wound healing to prevent premature suture breakage and wound cracking.
The second is its degradation characteristics. 3,5-dioxane will gradually degrade in the body. The degradation rate is related to many factors, such as the microstructure of the material, the enzyme environment in the body, etc. The user must be clear about its degradation law. For example, in the application of tissue repair scaffolds, the scaffold degrades too slowly, or the foreign matter remains in the body for a long time, triggering an inflammatory reaction; if the degradation is too fast, it may not provide enough support for tissue regeneration for a long time, affecting the repair effect. Therefore, the degradation process needs to be closely monitored, and the degradation progress of the material in the body can be evaluated by means of regular imaging examinations.
The other is biocompatibility. Although the material has certain biocompatibility, individual differences may cause adverse reactions in some patients. Before clinical use, patients should be asked in detail about their allergy history. In case of allergic patients, it is more necessary to use caution. During use, the patient should also be closely observed for adverse reactions such as redness, swelling, fever, and increased pain. Once found, appropriate measures should be taken immediately.
In addition, storage conditions cannot be ignored. 3,5-dioxane needs to be stored in a dry, cool and well-ventilated place, protected from moisture and high temperature environments. Due to its chemical structure characteristics, improper storage or material properties can be changed, such as after being damp, or affect its processing performance and final product quality, which in turn can have adverse effects on the use effect.
From the perspective of demand, this compound has great potential in the field of medicine. The research and development of many new drugs rely on its unique chemical structure to become a key intermediate. In order to seek new medical methods, if we want to make special drugs to treat intractable diseases, 3% 2C5-dioxabicyclo [2.2.1] heptane can help. Therefore, the pharmaceutical industry is gradually emerging, and its demand will also increase.
In the material industry, there is also potential. The creation of new polymer materials, if this compound is involved, may endow the material with specific properties, such as better heat resistance, wear resistance, corrosion resistance, etc. Today's demand for materials is prosperous in construction, electronics, transportation and other industries, with 3% 2C5-dioxabicyclo [2.2.1] heptane also has a wide world in it.
However, although its market prospects are beautiful, there are also challenges. The synthesis method must be simple, efficient, green and environmentally friendly. If the synthesis is cumbersome, the cost is high, and the demand is strong, it is also difficult to be widely distributed. And the regulations and supervision are increasingly stringent, related to its production and use, it must comply with standards in order to be smooth.
Furthermore, market competition is also an important factor. All industry players are looking at this business opportunity and competing to develop and produce. If you want to take the lead, you must make efforts on multiple ends such as technology, quality, price, and service to stand out.
In short, the market prospect of 3% 2C5-dioxabicyclo [2.2.1] heptane, opportunities and challenges coexist. Understand the situation, change it, make good use of opportunities, and overcome its challenges, in order to be in the market and seek long-term development.

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