Linshang Chemical
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3,5-Dichloroiodobenzene
Linshang Chemical
|
HS Code |
104083 |
| Chemical Formula | C6H3Cl2I |
| Molar Mass | 286.899 g/mol |
| Appearance | Off - white to pale yellow solid |
| Melting Point | 47 - 51 °C |
| Boiling Point | 233 - 235 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform, toluene |
| Purity | Typically available in purities like 95% or higher |
| Cas Number | 6306 - 38 - 1 |
| Isomeric Form | 1,3,5 - substitution pattern on benzene ring |
As an accredited 3,5-Dichloroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle of 3,5 - dichloroiodobenzene, well - sealed for chemical storage. |
| Storage | Store 3,5 - dichloroiodobenzene in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to decomposition. Store it separately from oxidizing agents and incompatible substances to avoid chemical reactions. |
| Shipping | 3,5 - dichloroiodobenzene is shipped in accordance with strict chemical transport regulations. Packed in sealed, corrosion - resistant containers, it's transported by specialized carriers to ensure safe and proper delivery. |
Competitive 3,5-Dichloroiodobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a trusted 3,5-Dichloroiodobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3,5-Dichloroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 3,5-dichloroiodobenzene?
3,5-Dinitrobenzoic acid is an important raw material and intermediate in the field of organic synthesis, and is widely used in many fields.
First, in the field of medicine, it plays a key role. It can be used as an important starting material for the synthesis of a variety of drugs. After a series of chemical reactions, it can be converted into compounds with specific pharmacological activities. For example, some drugs used in the treatment of cardiovascular diseases may be synthesized with 3,5-dinitrobenzoic acid as the base material. By modifying and modifying its structure, the drug is endowed with corresponding therapeutic effects, thus contributing to human health and well-being.
Second, in the dye industry, 3,5-dinitrobenzoic acid also plays an important role. It can be used as an intermediate in the synthesis of specific dyes, and by reacting with other chemical substances, dye molecules with specific colors and properties can be constructed. These dyes are widely used in textile, leather and other industries to give rich and colorful colors to fabrics and leather, meeting people's needs for beauty.
Furthermore, in the field of explosives manufacturing, 3,5-dinitrobenzoic acid also has its uses. Its molecular structure contains nitro, which is a common high-energy group in explosives. Through further chemical conversion and formulation design, it can be applied to the preparation of certain explosives, taking advantage of its ability to quickly release a large amount of energy under specific conditions to meet the needs of military, engineering blasting and other fields.
In addition, 3,5-dinitrobenzoic acid is often used as an important model compound in the study of organic synthetic chemistry. Through in-depth study of its chemical reaction properties, researchers explore new organic synthesis methods and strategies, expand the boundaries of organic synthetic chemistry, and provide theoretical support and practical experience for the synthesis of more complex organic compounds.
First, in the field of medicine, it plays a key role. It can be used as an important starting material for the synthesis of a variety of drugs. After a series of chemical reactions, it can be converted into compounds with specific pharmacological activities. For example, some drugs used in the treatment of cardiovascular diseases may be synthesized with 3,5-dinitrobenzoic acid as the base material. By modifying and modifying its structure, the drug is endowed with corresponding therapeutic effects, thus contributing to human health and well-being.
Second, in the dye industry, 3,5-dinitrobenzoic acid also plays an important role. It can be used as an intermediate in the synthesis of specific dyes, and by reacting with other chemical substances, dye molecules with specific colors and properties can be constructed. These dyes are widely used in textile, leather and other industries to give rich and colorful colors to fabrics and leather, meeting people's needs for beauty.
Furthermore, in the field of explosives manufacturing, 3,5-dinitrobenzoic acid also has its uses. Its molecular structure contains nitro, which is a common high-energy group in explosives. Through further chemical conversion and formulation design, it can be applied to the preparation of certain explosives, taking advantage of its ability to quickly release a large amount of energy under specific conditions to meet the needs of military, engineering blasting and other fields.
In addition, 3,5-dinitrobenzoic acid is often used as an important model compound in the study of organic synthetic chemistry. Through in-depth study of its chemical reaction properties, researchers explore new organic synthesis methods and strategies, expand the boundaries of organic synthetic chemistry, and provide theoretical support and practical experience for the synthesis of more complex organic compounds.
What are the synthesis methods of 3,5-dichloroiodobenzene?
There are several methods for the synthesis of 3,2,5-dibromothiophene. One method is to use thiophene as the starting material and prepare it by bromination reaction. In this method, liquid bromine is often used as the brominating agent, and in an appropriate solvent, such as dichloromethane, an appropriate catalyst, such as iron powder, is added to make it react. The electron cloud density on the ring of thiophene is high, and bromine is easy to undergo electrophilic substitution reaction with it, resulting in 3,2,5-dibromothiophene.
There are other compounds containing sulfur as the starting material, which are obtained by multi-step reaction. If a sulfide compound with a specific structure is prepared first, and then a series of steps such as cyclization and bromination, 3,2,5-dibromothiophene can also be prepared. Although such methods are complicated, if the starting materials are easy to obtain and the reaction conditions of each step are easy to control, it is also a feasible way.
Furthermore, it may be obtained by further bromination modification of existing bromothiophene derivatives. For example, one bromothiophene is prepared first, and then suitable reaction conditions are selected to further brominate it to obtain the target product 3,2,5-dibromothiophene. At this time, it is necessary to precisely control the reaction conditions to achieve the purpose of selective bromination and avoid generating too many unnecessary by-products. All these methods have their own advantages and disadvantages, depending on the specific factors such as the availability of raw materials, the controllability of reaction conditions, and production costs. Only by weighing and choosing them can an efficient and economical synthesis path be obtained.
There are other compounds containing sulfur as the starting material, which are obtained by multi-step reaction. If a sulfide compound with a specific structure is prepared first, and then a series of steps such as cyclization and bromination, 3,2,5-dibromothiophene can also be prepared. Although such methods are complicated, if the starting materials are easy to obtain and the reaction conditions of each step are easy to control, it is also a feasible way.
Furthermore, it may be obtained by further bromination modification of existing bromothiophene derivatives. For example, one bromothiophene is prepared first, and then suitable reaction conditions are selected to further brominate it to obtain the target product 3,2,5-dibromothiophene. At this time, it is necessary to precisely control the reaction conditions to achieve the purpose of selective bromination and avoid generating too many unnecessary by-products. All these methods have their own advantages and disadvantages, depending on the specific factors such as the availability of raw materials, the controllability of reaction conditions, and production costs. Only by weighing and choosing them can an efficient and economical synthesis path be obtained.
What are the physical properties of 3,5-dichloroiodobenzene?
3,5-Dibromobenzoic acid is an organic compound with unique physical properties. Its properties are usually white to light yellow crystalline powder, which is easy to store and use. It is a key raw material in many organic synthesis reactions.
From the point of view of melting point, it is about 200-204 ° C. The melting point is an important physical constant of a substance and can be used to determine its purity. If the substance contains impurities, the melting point will often be reduced and the melting range will be widened. Such a specific melting point allows for precise temperature control in related chemical production and experimental operations. For example, in the separation and purification process, it can be separated from the mixture according to the melting point characteristics.
Its solubility is also worthy of attention. It is slightly soluble in water, but soluble in organic solvents such as ethanol and ether. This solubility characteristic determines its behavior in different solvent systems. In organic synthesis, a suitable solvent is often selected according to the reaction requirements, and its solubility in organic solvents is used to make it fully contact and react with other reactants. For example, in a reaction system using ethanol as a solvent, 3,5-dibromobenzoic acid can be better dispersed and improve the reaction efficiency.
In addition, the density of 3,5-dibromobenzoic acid also has a specific value, which is of great significance when it comes to quality and volume conversion and related process design. In terms of material transportation and storage container design in chemical production, it is necessary to accurately calculate its density to ensure a smooth production process. Overall, these physical properties are a key foundation for the understanding and application of 3,5-dibromobenzoic acid.
From the point of view of melting point, it is about 200-204 ° C. The melting point is an important physical constant of a substance and can be used to determine its purity. If the substance contains impurities, the melting point will often be reduced and the melting range will be widened. Such a specific melting point allows for precise temperature control in related chemical production and experimental operations. For example, in the separation and purification process, it can be separated from the mixture according to the melting point characteristics.
Its solubility is also worthy of attention. It is slightly soluble in water, but soluble in organic solvents such as ethanol and ether. This solubility characteristic determines its behavior in different solvent systems. In organic synthesis, a suitable solvent is often selected according to the reaction requirements, and its solubility in organic solvents is used to make it fully contact and react with other reactants. For example, in a reaction system using ethanol as a solvent, 3,5-dibromobenzoic acid can be better dispersed and improve the reaction efficiency.
In addition, the density of 3,5-dibromobenzoic acid also has a specific value, which is of great significance when it comes to quality and volume conversion and related process design. In terms of material transportation and storage container design in chemical production, it is necessary to accurately calculate its density to ensure a smooth production process. Overall, these physical properties are a key foundation for the understanding and application of 3,5-dibromobenzoic acid.
What are the precautions for the storage and transportation of 3,5-dichloroiodobenzene?
3,5-Dihydroxybenzoic acid must pay attention to many key matters during storage and transportation. This is determined by its inherent chemical properties. A little carelessness may cause quality changes and even safety risks.
First storage environment. It should be placed in a cool, dry and well-ventilated place. Because the humid environment can easily cause it to absorb moisture, which may lead to deliquescence, affecting its purity and stability. If the storage temperature is too high, it may also accelerate its chemical reaction process and lead to deterioration. And it should be kept away from fire and heat sources, because it has a certain flammability, in case of open flame, hot topic or can cause combustion risk.
Furthermore, the packaging must be tight. Use packaging materials with good sealing performance, such as glass bottles, plastic bottles, etc., to prevent the intrusion of external factors such as air and moisture. The packaging material should not chemically react with 3,5-dihydroxybenzoic acid to avoid affecting its quality.
As for the transportation link, it should not be taken lightly. Make sure that the transportation tool is clean and dry, and there are no other substances that may react with it. Avoid severe vibration and collision during transportation to prevent package damage. If it encounters high temperature weather during transportation, appropriate cooling measures should be taken to ensure that the transportation environment meets its storage requirements.
When loading and unloading, the operator must handle it with care, and it is strictly forbidden to operate brutally to prevent damage to the packaging and leakage of 3,5-dihydroxybenzoic acid. Once a leak occurs, it needs to be cleaned up in time to prevent it from polluting the environment, and at the same time, it is also necessary to avoid personal contact to prevent harm to the human body.
After all, whether it is storing or transporting 3,5-dihydroxybenzoic acid, it is necessary to strictly follow the corresponding specifications and requirements to ensure its quality and safety.
First storage environment. It should be placed in a cool, dry and well-ventilated place. Because the humid environment can easily cause it to absorb moisture, which may lead to deliquescence, affecting its purity and stability. If the storage temperature is too high, it may also accelerate its chemical reaction process and lead to deterioration. And it should be kept away from fire and heat sources, because it has a certain flammability, in case of open flame, hot topic or can cause combustion risk.
Furthermore, the packaging must be tight. Use packaging materials with good sealing performance, such as glass bottles, plastic bottles, etc., to prevent the intrusion of external factors such as air and moisture. The packaging material should not chemically react with 3,5-dihydroxybenzoic acid to avoid affecting its quality.
As for the transportation link, it should not be taken lightly. Make sure that the transportation tool is clean and dry, and there are no other substances that may react with it. Avoid severe vibration and collision during transportation to prevent package damage. If it encounters high temperature weather during transportation, appropriate cooling measures should be taken to ensure that the transportation environment meets its storage requirements.
When loading and unloading, the operator must handle it with care, and it is strictly forbidden to operate brutally to prevent damage to the packaging and leakage of 3,5-dihydroxybenzoic acid. Once a leak occurs, it needs to be cleaned up in time to prevent it from polluting the environment, and at the same time, it is also necessary to avoid personal contact to prevent harm to the human body.
After all, whether it is storing or transporting 3,5-dihydroxybenzoic acid, it is necessary to strictly follow the corresponding specifications and requirements to ensure its quality and safety.
What is the market price of 3,5-dichloroiodobenzene?
What is the market price of 3% 2C5-dibromobenzaldehyde today? This is a concern for everyone. However, it is not easy to know its price, and its price is determined by many factors.
First, the price of raw materials is one of the keys. If the raw material for preparing 3% 2C5-dibromobenzaldehyde is expensive, the price of the finished product will also rise; if the raw material is cheap, the price of the finished product may drop.
Second, the preparation method also has an impact. If the preparation method is complicated, requires a lot of manpower and material resources, and costs a lot, its price will be high; if the preparation method is simple, the cost will be reduced, and the price may be accessible to the people.
Third, the supply and demand relationship of the market also affects its price. If there are many people who want it, and there are few people who supply it, the price will rise; if the supply exceeds the demand, the price may decline.
Fourth, the difference in region also makes the price different. In prosperous places, the cost is higher, and the price may be slightly more expensive; in remote places, the cost is lower, and the price may be slightly cheaper.
Therefore, in order to determine the price of 3% 2C5-dibromobenzaldehyde in the market, it is necessary to carefully consider the price of raw materials, the method of preparation, the situation of supply and demand, and the differences in regions.
First, the price of raw materials is one of the keys. If the raw material for preparing 3% 2C5-dibromobenzaldehyde is expensive, the price of the finished product will also rise; if the raw material is cheap, the price of the finished product may drop.
Second, the preparation method also has an impact. If the preparation method is complicated, requires a lot of manpower and material resources, and costs a lot, its price will be high; if the preparation method is simple, the cost will be reduced, and the price may be accessible to the people.
Third, the supply and demand relationship of the market also affects its price. If there are many people who want it, and there are few people who supply it, the price will rise; if the supply exceeds the demand, the price may decline.
Fourth, the difference in region also makes the price different. In prosperous places, the cost is higher, and the price may be slightly more expensive; in remote places, the cost is lower, and the price may be slightly cheaper.
Therefore, in order to determine the price of 3% 2C5-dibromobenzaldehyde in the market, it is necessary to carefully consider the price of raw materials, the method of preparation, the situation of supply and demand, and the differences in regions.
What are the main uses of 3,5-dichloroiodobenzene?
3,2,5-dioxabicyclo [2.2.1] heptane, which has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many drugs. For example, some anti-infective drugs, it is used to build special chemical structures to enhance the effect of drugs on pathogens and improve efficacy. In the field of materials science, it participates in the preparation of high-performance polymer materials. Adding this compound can optimize the thermal stability and mechanical properties of materials, making materials suitable for high-end fields such as aerospace and electronic devices. In organic synthetic chemistry, it is often used as a unique structural module to help synthesize complex natural products and new organic compounds, expand the boundaries of organic synthesis, and provide the possibility for the creation of novel functional molecules.
"Tiangong Kaiwu" says: "The things in the world have their own uses, either in daily use, or hidden in subtle techniques. 3,2,5-dioxabicyclo [2.2.1] Although heptane is small, it is used in medicine, materials, and synthesis. Although it is the foundation of medicine, it can help healers to cure diseases; for the quality of materials, it can make utensils strong. When synthesized, it is also a wonderful tool in the hands of skilled craftsmen, turning the ordinary into magic. It is based on the observation that there is no big or small thing, but only those who use it well can make the best use and benefit the world."
"Tiangong Kaiwu" says: "The things in the world have their own uses, either in daily use, or hidden in subtle techniques. 3,2,5-dioxabicyclo [2.2.1] Although heptane is small, it is used in medicine, materials, and synthesis. Although it is the foundation of medicine, it can help healers to cure diseases; for the quality of materials, it can make utensils strong. When synthesized, it is also a wonderful tool in the hands of skilled craftsmen, turning the ordinary into magic. It is based on the observation that there is no big or small thing, but only those who use it well can make the best use and benefit the world."
What are the physical properties of 3,5-dichloroiodobenzene?
3,5-Dinitrobenzoic acid is one of the organic compounds. Its physical properties are quite unique.
Under normal temperature and pressure, it often shows a yellow crystalline state, and its quality is relatively stable. Its melting point is quite high, about 169-171 ° C. This characteristic allows it to maintain a solid state within a specific temperature range.
In terms of solubility, it is extremely difficult to dissolve in water. Due to the characteristics of the molecular structure, it is difficult to form an effective interaction with water molecules. However, in organic solvents such as ethanol and ether, it exhibits good solubility, because the molecules of the organic solvent are compatible with the intermolecular forces of 3,5-dinitrobenzoic acid, which can make it uniformly dispersed.
Its density is also an important physical property, which is heavier than that of water. This is due to the combination of the types and quantities of atoms in the molecule, resulting in a larger mass per unit volume.
In addition, 3,5-dinitrobenzoic acid has a certain volatility, but its volatility is weak, and the tendency of molecules to escape to the gas phase is small at room temperature. These physical properties are closely related to its molecular structure. The introduction of nitro groups greatly affects the intermolecular forces, polarity and other factors, thus creating the above unique physical properties, which play a key role in the application of chemical industry, medicine and many other fields.
Under normal temperature and pressure, it often shows a yellow crystalline state, and its quality is relatively stable. Its melting point is quite high, about 169-171 ° C. This characteristic allows it to maintain a solid state within a specific temperature range.
In terms of solubility, it is extremely difficult to dissolve in water. Due to the characteristics of the molecular structure, it is difficult to form an effective interaction with water molecules. However, in organic solvents such as ethanol and ether, it exhibits good solubility, because the molecules of the organic solvent are compatible with the intermolecular forces of 3,5-dinitrobenzoic acid, which can make it uniformly dispersed.
Its density is also an important physical property, which is heavier than that of water. This is due to the combination of the types and quantities of atoms in the molecule, resulting in a larger mass per unit volume.
In addition, 3,5-dinitrobenzoic acid has a certain volatility, but its volatility is weak, and the tendency of molecules to escape to the gas phase is small at room temperature. These physical properties are closely related to its molecular structure. The introduction of nitro groups greatly affects the intermolecular forces, polarity and other factors, thus creating the above unique physical properties, which play a key role in the application of chemical industry, medicine and many other fields.
What are the synthesis methods of 3,5-dichloroiodobenzene?
3,5-Dibromobenzoic acid is a key intermediate in organic synthesis. Its synthesis method is generally as follows:
First, benzoic acid is used as the starting material and is prepared by bromination reaction. Liquid bromine can be used as a bromination reagent. In the presence of appropriate catalysts, such as iron powder and iron tribromide, benzoic acid and liquid bromine undergo electrophilic substitution reaction under heating conditions. In this reaction, iron reacts with bromine first to form iron tribromide, which promotes the polarization of bromine molecules and is more likely to launch electrophilic attacks on the benzene ring. Because the carboxyl group is the meta-locator, the bromine atom mainly replaces the hydrogen atom at the carboxyl group interposition on the benzene ring, and then generates 3,5-dibromobenzoic acid. The raw materials of this method are easy to obtain and relatively convenient to operate. However, the reaction conditions need to be precisely controlled, otherwise it is easy to produce polybromination by-products. The relevant reaction formulas are as follows:
$C_ {7} H_ {6} O_ {2} + 2Br_ {2}\ xrightarrow [] {FeBr_ {3}} C_ {7} H_ {4} Br_ {2} O_ {2} + 2HBr $
Second, with m-bromotoluene as the raw material, the methyl group is first converted into a carboxyl group by oxidation reaction, and then brominated. M-bromotoluene can be oxidized to isobromobenzoic acid under acidic or basic conditions using strong oxidants such as potassium permanganate and potassium dichromate. Next, isobromobenzoic acid is further reacted with bromine under conditions similar to the above bromination reaction, and a second bromine atom is introduced at the carboxyl group meta-position to obtain 3,5-dibromobenzoic acid. This route has a little more steps, but the selectivity of each step is relatively good, and the purity of the product is easier to improve. The relevant reaction process is:
$C_ {7} H_ {7} Br + 2KMnO_ {4}\ xrightarrow [] {OH ^ -} C_ {7} H_ {5} BrO_ {2} + 2MnO_ {2} + 2KOH + H_ {2} O $
$C_ {7} H_ {5} BrO_ {2} + Br_ {2}\ xrightarrow [] {FeBr_ {3}} C_ {7} H_ {4} Br_ {2} O_ {2} + HBr $
Third, with isophthalic acid as raw material, first protect one of the carboxyl groups to prevent it from participating in the reaction during bromination. The commonly used carboxyl protecting groups include methyl ester groups, etc. The esterification reaction between isophthalic acid and methanol catalyzed by concentrated sulfuric acid protects one of the carboxyl groups. Subsequently, the remaining benzene ring is brominated to generate 3-bromo-5-carboxybenzoate methyl ester, and then the protecting group is removed by hydrolysis to obtain 3,5-dibromobenzoic acid. Although this method is more complicated and requires the introduction and removal of protective groups, the control of the reaction check point is more accurate, which can effectively reduce unnecessary side reactions and obtain high-purity target products. The relevant reaction process is as follows:
$C_ {8} H_ {6} O_ {4} + CH_ {3} OH\ xrightarrow [] {H_ {2} SO_ {4}} C_ {9} H_ {8} O_ {4} + H_ {2} O $
$C_ {9} H_ {8} O_ {4} + {2}\ xrightarrow [] {FeBr_ {3}} C_ {9} H_ {7} BrO_ {4} + HBr $
$C_ {9} H_ {7} C_ {4} + H_ {2} O\ xrightarrow [] {H ^ +} O_ {7} CH_ {4} H_ {2} SO_ {2} + C_ {3} OH $
First, benzoic acid is used as the starting material and is prepared by bromination reaction. Liquid bromine can be used as a bromination reagent. In the presence of appropriate catalysts, such as iron powder and iron tribromide, benzoic acid and liquid bromine undergo electrophilic substitution reaction under heating conditions. In this reaction, iron reacts with bromine first to form iron tribromide, which promotes the polarization of bromine molecules and is more likely to launch electrophilic attacks on the benzene ring. Because the carboxyl group is the meta-locator, the bromine atom mainly replaces the hydrogen atom at the carboxyl group interposition on the benzene ring, and then generates 3,5-dibromobenzoic acid. The raw materials of this method are easy to obtain and relatively convenient to operate. However, the reaction conditions need to be precisely controlled, otherwise it is easy to produce polybromination by-products. The relevant reaction formulas are as follows:
$C_ {7} H_ {6} O_ {2} + 2Br_ {2}\ xrightarrow [] {FeBr_ {3}} C_ {7} H_ {4} Br_ {2} O_ {2} + 2HBr $
Second, with m-bromotoluene as the raw material, the methyl group is first converted into a carboxyl group by oxidation reaction, and then brominated. M-bromotoluene can be oxidized to isobromobenzoic acid under acidic or basic conditions using strong oxidants such as potassium permanganate and potassium dichromate. Next, isobromobenzoic acid is further reacted with bromine under conditions similar to the above bromination reaction, and a second bromine atom is introduced at the carboxyl group meta-position to obtain 3,5-dibromobenzoic acid. This route has a little more steps, but the selectivity of each step is relatively good, and the purity of the product is easier to improve. The relevant reaction process is:
$C_ {7} H_ {7} Br + 2KMnO_ {4}\ xrightarrow [] {OH ^ -} C_ {7} H_ {5} BrO_ {2} + 2MnO_ {2} + 2KOH + H_ {2} O $
$C_ {7} H_ {5} BrO_ {2} + Br_ {2}\ xrightarrow [] {FeBr_ {3}} C_ {7} H_ {4} Br_ {2} O_ {2} + HBr $
Third, with isophthalic acid as raw material, first protect one of the carboxyl groups to prevent it from participating in the reaction during bromination. The commonly used carboxyl protecting groups include methyl ester groups, etc. The esterification reaction between isophthalic acid and methanol catalyzed by concentrated sulfuric acid protects one of the carboxyl groups. Subsequently, the remaining benzene ring is brominated to generate 3-bromo-5-carboxybenzoate methyl ester, and then the protecting group is removed by hydrolysis to obtain 3,5-dibromobenzoic acid. Although this method is more complicated and requires the introduction and removal of protective groups, the control of the reaction check point is more accurate, which can effectively reduce unnecessary side reactions and obtain high-purity target products. The relevant reaction process is as follows:
$C_ {8} H_ {6} O_ {4} + CH_ {3} OH\ xrightarrow [] {H_ {2} SO_ {4}} C_ {9} H_ {8} O_ {4} + H_ {2} O $
$C_ {9} H_ {8} O_ {4} + {2}\ xrightarrow [] {FeBr_ {3}} C_ {9} H_ {7} BrO_ {4} + HBr $
$C_ {9} H_ {7} C_ {4} + H_ {2} O\ xrightarrow [] {H ^ +} O_ {7} CH_ {4} H_ {2} SO_ {2} + C_ {3} OH $
What are the precautions for storing and transporting 3,5-dichloroiodobenzene?
3,5-Dinitrobenzoic acid should be stored with caution during storage and transportation.
It is highly oxidizing and explosive. When storing, it should be in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent the reaction from getting out of control due to the increase in temperature. The temperature and humidity of the warehouse should be tightly controlled. The temperature should be maintained within a specific range, and the humidity should not be too high, so as not to affect its stability.
The storage container must be strong and sealed to prevent leakage. It must not be mixed with reducing substances, flammable substances, etc., because it encounters such substances, it is easy to cause violent chemical reactions and risk fire or explosion.
During transportation, it is also necessary to ensure that the packaging is intact. When handling, it is necessary to handle it with care. It is strictly forbidden to drop or impact to prevent the package from breaking and causing it to leak. Transportation vehicles should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment for emergencies. Transportation personnel also need to be professionally trained and familiar with its dangerous characteristics and emergency treatment methods before they can perform their duties.
In short, 3,5-dinitrobenzoic acid should not be slack in the storage and transportation process, from the choice of storage environment, the choice of containers, to the operation specifications of transportation, so as to ensure the safety of the process and avoid accidents.
It is highly oxidizing and explosive. When storing, it should be in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent the reaction from getting out of control due to the increase in temperature. The temperature and humidity of the warehouse should be tightly controlled. The temperature should be maintained within a specific range, and the humidity should not be too high, so as not to affect its stability.
The storage container must be strong and sealed to prevent leakage. It must not be mixed with reducing substances, flammable substances, etc., because it encounters such substances, it is easy to cause violent chemical reactions and risk fire or explosion.
During transportation, it is also necessary to ensure that the packaging is intact. When handling, it is necessary to handle it with care. It is strictly forbidden to drop or impact to prevent the package from breaking and causing it to leak. Transportation vehicles should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment for emergencies. Transportation personnel also need to be professionally trained and familiar with its dangerous characteristics and emergency treatment methods before they can perform their duties.
In short, 3,5-dinitrobenzoic acid should not be slack in the storage and transportation process, from the choice of storage environment, the choice of containers, to the operation specifications of transportation, so as to ensure the safety of the process and avoid accidents.
What is the approximate market price of 3,5-dichloroiodobenzene?
The price of 3,5-dibromobenzoic acid in the market is difficult to determine, because it is multi-terminal. This compound has a wide range of uses and is involved in the fields of medicine, pesticides, materials, etc. However, its price often varies according to the supply and demand of the city, manufacturing costs, and quality specifications.
Looking at the supply and demand side, if the market has a strong demand for 3,5-dibromobenzoic acid and the supply is limited, the price will tend to rise. If pharmaceutical research and development is advancing by leaps and bounds, new drug creation requires this compound as a raw material, causing its demand to exceed the supply, and the price will rise. On the contrary, if the supply exceeds the demand, the price may fall.
Manufacturing costs are also a major factor. The preparation process, or involving complex reactions, requires special reagents and equipment, and the price of raw materials, energy consumption, labor costs, etc. will affect the total cost. If the price of raw materials rises, or energy consumption increases, the manufacturing cost rises, and the market price also rises.
Different quality specifications, the price is also different. High-purity, high-quality 3,5-dibromobenzoic acid, due to the difficulty of preparation, strict testing requirements, the price is often higher than that of ordinary quality. In the fields of fine chemicals, high-end pharmaceutical synthesis, etc., the quality requirements are extremely high, and we are willing to pay a high price for it.
Generally speaking, the market price may range from tens to hundreds of yuan per kilogram, but this is only a rough figure. To know the exact price, you must consult the chemical raw material supplier, or check the real-time quotation of the chemical product trading platform to get the near-true price.
Looking at the supply and demand side, if the market has a strong demand for 3,5-dibromobenzoic acid and the supply is limited, the price will tend to rise. If pharmaceutical research and development is advancing by leaps and bounds, new drug creation requires this compound as a raw material, causing its demand to exceed the supply, and the price will rise. On the contrary, if the supply exceeds the demand, the price may fall.
Manufacturing costs are also a major factor. The preparation process, or involving complex reactions, requires special reagents and equipment, and the price of raw materials, energy consumption, labor costs, etc. will affect the total cost. If the price of raw materials rises, or energy consumption increases, the manufacturing cost rises, and the market price also rises.
Different quality specifications, the price is also different. High-purity, high-quality 3,5-dibromobenzoic acid, due to the difficulty of preparation, strict testing requirements, the price is often higher than that of ordinary quality. In the fields of fine chemicals, high-end pharmaceutical synthesis, etc., the quality requirements are extremely high, and we are willing to pay a high price for it.
Generally speaking, the market price may range from tens to hundreds of yuan per kilogram, but this is only a rough figure. To know the exact price, you must consult the chemical raw material supplier, or check the real-time quotation of the chemical product trading platform to get the near-true price.
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