3-Amino-4-Carboxy-1-Chlorobenzene
Linshang Chemical
HS Code |
470335 |
Chemical Formula | C7H6ClNO2 |
Molar Mass | 171.58 g/mol |
Appearance | Solid (description may vary) |
Melting Point | Data needed |
Boiling Point | Data needed |
Solubility In Water | Data needed |
Solubility In Organic Solvents | Data needed |
Density | Data needed |
Pka Value | Data needed |
Logp Value | Data needed |
As an accredited 3-Amino-4-Carboxy-1-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 kg of 3 - amino - 4 - carboxy - 1 - chlorobenzene packaged in a sealed, chemical - resistant bag. |
Storage | 3 - amino - 4 - carboxy - 1 - chlorobenzene should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and contamination. It is advisable to store it separately from incompatible substances to avoid potential chemical reactions. Label the storage container clearly with relevant hazard information. |
Shipping | 3 - amino - 4 - carboxy - 1 - chlorobenzene should be shipped in well - sealed containers, compliant with chemical transport regulations. Ensure protection from moisture, heat, and physical damage during transit to maintain its integrity. |
Competitive 3-Amino-4-Carboxy-1-Chlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 3-Amino-4-Carboxy-1-Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of materials science, due to its special chemical functional groups, it can be chemically modified or polymerized into polymer material systems. Amino and carboxyl groups can participate in the polycondensation reaction and copolymerize with other monomers, thereby changing the chemical and physical properties of materials, such as enhancing the hydrophilicity of materials, improving the mechanical properties and thermal stability of materials, etc., providing the possibility for the preparation of high-performance functional materials.
In the field of dye chemistry, 3-amino-4-carboxyl-1-chlorobenzene may be used as a key raw material for synthesizing dyes. The amino and carboxyl groups can be combined with the parent structure of the dye to give the dye a specific color and dyeing properties. The introduction of chlorine atoms can change the electron cloud distribution of the dye molecule, affect its light absorption and emission characteristics, and make the dye exhibit excellent dyeing fastness and color brightness during the dyeing process of fabrics, leather and other materials.
In addition, in the basic research of organic synthetic chemistry, 3-amino-4-carboxyl-1-chlorobenzene, as a typical multifunctional aromatic compound, is often used as a model substrate to explore new organic reaction mechanisms, develop novel synthetic methods, and provide important support for the theoretical development and practical innovation of organic chemistry.
Looking at its appearance, under room temperature and pressure, it is mostly solid. As for the exact color, it may vary due to purity and other factors. It is usually white to light yellow powder with fine texture.
When it comes to solubility, the solubility of this compound in water is quite limited. Although its molecular structure contains carboxyl groups and has a certain hydrophilicity, the presence of chlorine atoms and benzene rings makes its overall hydrophobicity strong, so it does not dissolve well in water. However, some organic solvents, such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), have good solubility and can form specific interactions with solvent molecules, resulting in uniform dispersion.
Its melting point is also an important physical property. The melting point is measured experimentally in a specific temperature range. This temperature value is the inherent property of the compound and can be used as the basis for identification and purity judgment. The determination of the melting point is closely related to the intermolecular forces. The conjugate structure of the benzene ring and the interaction between amino and carboxyl groups all affect the intermolecular forces, which in turn determine the melting point.
In addition, the density of 3-amino-4-carboxyl-1-chlorobenzene cannot be ignored. Density reflects the mass per unit volume of a substance and is restricted by molecular structure and packing method. Due to the characteristics of the spatial arrangement of benzene rings and functional groups, its density has a specific value. This value is an important parameter in the process of chemical production, separation and purification, etc., and is related to material measurement and process design.
And its volatility is weak. Due to the strong interactions between molecules such as hydrogen bonds and van der Waals forces, it is difficult for molecules to escape from the surface. This property is of great significance during storage and use, and can reduce the risk of loss of volatile substances and environmental pollution.
In summary, the physical properties of 3-amino-4-carboxyl-1-chlorobenzene are diverse and interrelated, which is of great significance in many fields of chemical research and industrial production. In-depth understanding of its properties lays the foundation for rational application.
In terms of its physical properties, this compound is mostly in a solid state at room temperature, but the specific properties may vary depending on purity and crystallization conditions. Its melting point, boiling point and other parameters depend on accurate experimental determination, due to the particularity of intermolecular forces and structures, which may fluctuate within the specific range of relevant literature.
In terms of chemical properties, the amino groups, carboxyl groups and chlorine atoms contained in the 3-amino-4-carboxyl-1-chlorobenzene molecule each have their own abilities, resulting in rich and variable chemical activities. Amino groups are basic and can neutralize with acids to form corresponding salts. And amino groups can participate in nucleophilic substitution reactions. In organic synthesis, they can be combined with electrophilic reagents such as halogenated hydrocarbons to form new carbon-nitrogen bonds and expand the structure of molecules.
The acidity of carboxyl groups makes them neutralize with bases to form carboxylates. At the same time, the carboxyl group can participate in the esterification reaction and form ester compounds with alcohols under the action of catalysts, which is an important path for organic synthesis and preparation of esters.
Although the chlorine atom is a halogen atom, it has unique reactivity in the molecule. It can undergo nucleophilic substitution reaction. When encountering suitable nucleophilic reagents, the chlorine atom can be replaced and new functional groups can be introduced, providing diverse possibilities for the structural modification of molecules.
In addition, the benzene ring structure of this compound endows it with aromaticity, and the substituents on the benzene ring interact with each other, or cause electrophilic substitution reactions on the benzene ring. The localization effect of different substituents affects the regioselectivity of the reaction, which is of great significance for the synthesis of derivatives with specific structures
In the arena of organic synthesis, the above chemical properties of 3-amino-4-carboxyl-1-chlorphenyl are often used as key intermediates to assist in the construction of various complex organic compounds, and have potential applications in pharmaceutical chemistry, materials science and other fields.
First take the derivative of benzene and apply the technique of halogenation. During halogenation, chlorine is selected as the halogen source, and a specific halogenation reagent and reaction conditions are used to replace the chlorine atom at a specific position in the benzene ring to obtain the chlorine-containing benzene derivative. This step requires careful selection of the reaction solvent, temperature, and time to ensure that the halogenation reaction is accurate and efficient, so that the chlorine atom falls into the desired position.
The reaction of amination is performed at the second time. Using chlorine-containing benzene derivatives as substrates, using amination reagents, the amino group is substituted for the other groups on the benzene ring, and the amino group is introduced at the 3 position. The method of amination, or the reaction mechanism such as nucleophilic substitution, during which the pH of the reaction system and the type and dosage of the catalyst must be regulated in detail, so that the amination can proceed smoothly and avoid the disturbance of side reactions.
The step of carboxylation is finally carried out. The benzene derivative with chlorine and amino groups is introduced into the 4 position of the benzene ring through the action of carboxylation reagents. The way of carboxylation can be based on different reaction paths, such as Grignard reagent method or other carboxylation methods. This step should also pay attention to the control of reaction conditions, such as reaction temperature, solvent properties, etc., in order to obtain a pure 3-amino-4-carboxyl-1-chlorobenzene product.
There are other methods, or change the reaction sequence, carboxylation first, subhalogenation, and then amination; or choose other starting materials, according to different reaction mechanisms, following the laws of chemical transformation, after several steps of reaction, the purpose of synthesizing this compound can also be achieved. In short, the method of synthesis should be carefully weighed and selected according to the availability of raw materials, the difficulty of reaction, the purity and yield of the product, and many other factors.
First, purity has a great impact on price. If the purity is extremely high, it is almost flawless, and it is suitable for high-end scientific research or special industrial use, the price will be high; on the contrary, if the purity is slightly lower, it is suitable for scenarios with low requirements, and the price should be relatively low.
Second, the relationship between output and demand is also critical. If the market demand is large, but the output is limited, the supply is in short supply, and the price will rise; if the demand is low, the output is abundant, and the supply is in excess, the price may decline.
Third, the difficulty of preparation is also related to the price. If the synthesis of this compound requires complicated steps, rare raw materials or special conditions, the cost is high and the price is also high; if the preparation is relatively simple, the cost is controllable, and the price is close to the people.
Fourth, the price varies depending on the supplier. Different merchants may set high and low prices due to their own cost structures and business strategies.
From the perspective of "Tiangong Kaiwu", the price of everything is intertwined by its difficulty of production, supply and demand conditions, and many other reasons. However, to determine the exact price range of 3-amino-4-carboxy-1-chlorobenzene, it is necessary to investigate the chemical raw material market in detail, consult relevant suppliers or industry insiders, and obtain a more accurate figure.

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