3-Amino-4-Chloro-Benzenesulfonic Acid
Linshang Chemical
HS Code |
859693 |
Chemical Formula | C6H6ClNO3S |
Molecular Weight | 207.64 |
Appearance | Solid |
Color | Typically white to off - white |
Odor | Odorless (usually) |
Solubility In Water | Moderately soluble |
Melting Point | 160 - 165 °C |
Density | 1.62 g/cm³ (approximate) |
Pka Value | Around 1.5 (approximate for the sulfonic acid group) |
Stability | Stable under normal conditions |
As an accredited 3-Amino-4-Chloro-Benzenesulfonic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 25 - kg bag packaging for 3 - amino - 4 - chloro - benzenesulfonic Acid. |
Storage | 3 - amino - 4 - chloro - benzenesulfonic acid should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in tightly sealed containers to prevent moisture absorption and potential reactions. Separate from incompatible substances to avoid chemical hazards and ensure the integrity of the compound during storage. |
Shipping | 3 - amino - 4 - chloro - benzenesulfonic acid should be shipped in well - sealed, corrosion - resistant containers. Ensure compliance with hazardous chemical shipping regulations, maintaining proper labeling and temperature control during transit. |
Competitive 3-Amino-4-Chloro-Benzenesulfonic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 3-Amino-4-Chloro-Benzenesulfonic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
- ** Use of Hydroxyl Groups **:
- ** Pharmaceutical Fields **: Many drug molecules contain hydroxyl groups, because they can enhance the water solubility of drugs, which is conducive to drug transportation and metabolism in the body. For example, the common antibiotic amoxicillin has a bactericidal effect by virtue of the action of hydroxyl groups in the molecule with the bacterial cell wall. And hydroxyl groups can participate in the hydrogen bonding between drugs and receptor molecules, enabling drugs to precisely bind to specific targets and enhance drug efficacy.
- ** Materials Science **: In polymer materials, hydroxyl-containing polymers are widely used. Like polyester materials, through the condensation reaction of hydroxyl-containing monomers, hydrogen bonds can be formed between the hydroxyl groups, which improves the strength and stability of the material. The hydroxyl resin in the coating can react with the curing agent to form a strong paint film, which enhances the wear resistance and corrosion resistance of the coating.
- ** Biochemistry **: Many important molecules in organisms contain hydroxyl groups, such as glucose, as energy storage and supply substances. Multiple hydroxyl groups give them good water solubility, which is convenient for transportation and metabolism in organisms. In addition, hydroxyl groups play a key role in enzyme catalytic reactions, and the hydroxyl groups in the active center of the enzyme can participate in the process of substrate binding and catalysis.
- ** Use of thiol groups **:
- ** Pharmaceutical field **: Some drugs rely on thiol groups to function, such as detoxifying drug dimercaptopropanol. The thiol group in its molecule can bind to heavy metal ions to form a stable complex, which is excreted from the body to relieve heavy metal poisoning. And thiol groups can participate in the regulation of protein structure and function, and maintain the correct spatial conformation of proteins.
- ** Materials Science **: Mercapto groups can be used to prepare special functional materials, such as thiol-modified nanoparticles, which can enhance their dispersion and stability in solution, and are widely used in biological imaging and drug delivery. Mercapto-containing polymers and compounds containing double bonds can perform click chemical reactions to rapidly form cross-linked structures and prepare intelligent responsive materials.
- ** Biochemistry **: Cysteine residues in proteins contain thiol groups, which are essential for protein structure and function. The formation and breaking of disulfide bonds can regulate protein activity and conformation. Glutathione is an important antioxidant, and thiol groups can scavenge free radicals in the body and protect cells from oxidative damage.
Hydrogen groups are highly active. In water molecules, hydrogen groups are connected to oxygen atoms, and by means of hydrogen bonds, water has a higher boiling point and melting point. The force of this hydrogen bond makes water molecules attract each other closely. To convert water from liquid to gaseous state, it takes more energy to break hydrogen bonds, so the boiling point of water can reach 100 degrees. And the structure of the hydrogen gene gives water good solubility. Many ionic compounds and polar molecules are soluble in water because of their interaction with hydrogen groups.
Furthermore, hydrogen groups participate in many chemical reactions. In acid-base reactions, compounds containing hydrogen groups, such as acids, can release hydrogen ions and exhibit acidic properties. For example, hydrochloric acid can completely ionize hydrogen ions in water, neutralize with bases, and form salts and water.
As for thiol groups, their physical properties are also unique. Mercapto groups have a special odor and are commonly found in some sulfur-containing proteins and amino acids, such as cysteine. This special odor can be detected in certain biological processes and substances.
The chemical activity of thiol groups is also quite high. Mercapto groups are easily oxidized, and two thiol groups can form disulfide bonds through oxidation reactions. This disulfide bond is crucial for the structural stability of proteins. Many proteins maintain their specific spatial conformations through disulfide bonds to perform normal biological functions. For example, insulin, which has a disulfide bond in its molecule, is indispensable for maintaining the active structure of insulin.
In addition, sulfhydryl groups can strongly interact with metal ions to form stable complexes. This property plays a key role in the transport and detoxification of metal ions in vivo, and can also be used for the separation and purification of metal ions in industry.
Nitrogen also has its unique properties. Its properties are relatively stable, and it does not react violently with other things at room temperature. It is often used as a protective gas, such as filling food packaging with nitrogen, which can prevent food from oxidizing and deteriorating, just like a loyal guard, guarding the quality of food.
Hydrofluoric acid is a substance with special chemical properties. Although it is not extremely acidic, it is very corrosive. It can react with many metals, oxides, etc., such as silica in glass, so it is often stored in plastic containers. If accidentally touched, it can cause serious burns and is extremely harmful. It reacts with alkali to generate corresponding salts and water, following the general law of acid-base reaction. In industry, hydrofluoric acid is often used in the fields of etching glass, refining metals, etc., showing its unique functions.
However, if you use ancient thinking to deduce the preparation idea of similar compounds, you can start from natural material extraction and simple chemical reactions. In ancient times, it was good to obtain raw materials from natural resources such as minerals and plants. If you want to make compounds containing bromine and sulfonic acid groups, you can first find bromine-containing minerals. In ancient times, although the elemental substance of bromine was unknown, some salt lakes, seawater or bromine-containing salts could be enriched by evaporation, crystallization, etc.
As for the introduction of sulfonic acid groups, although there was no modern precise means in ancient times, it could be converted by sulfur-related compounds. If sulfur is used as the starting point, sulfur dioxide is burned to form sulfur trioxide, which can be similar to natural products containing benzene rings (such as some plant extracts or simple benzene ring structures). Under specific conditions, similar sulfonation reactions may occur. However, due to the lack of precise control, the product is complex and difficult to purify.
If amino groups are introduced, there is no synthetic ammonia industry in ancient times to obtain ammonia sources to produce amino groups. Nitrogen-containing natural organic compounds, such as proteins, can be hydrolyzed to obtain amino acids. After complex transformation of some amino acids, the amino group may theoretically be connected to the benzene ring system. However, this process requires delicate design and repeated attempts, and it is difficult to achieve accurately with ancient technology. In short, with the technology of the "Tiangong Kaiwu" era, although there is a direction of thinking, it is not easy to prepare "amino-4-bromobenzene sulfonic acid".
The first to bear the brunt is related to storage. Oxygen, because of its combustion-supporting properties, must be kept away from fire and heat sources, and stored in a cool and ventilated warehouse. And oxygen, flammable and combustible materials should be placed separately, and mixed storage should not be avoided to prevent accidental explosion. As for amino groups, many compounds containing amino groups, many of which are toxic and corrosive, should be stored in a dry and clean place to avoid mixing with acids, oxidants, etc., because the two meet, or cause violent chemical reactions, resulting in dangerous emergencies. Mercaptoacetic acid, corrosive and pungent odor, should be stored in a cool, ventilated warehouse, away from fire, heat sources, should be stored separately from oxidants, acids, alkalis, can not be mixed storage and transportation, because of its active chemical properties, encounter the above substances, fear of accidents.
Furthermore, when it comes to transportation. When transporting oxygen, the transport vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment, and the compartment must be thoroughly cleaned, and no combustible substances should be left. During transportation, it is necessary to ensure that the container does not leak, collapse, fall, or damage, avoid sun exposure, and stay away from high temperature areas. When transporting substances containing amino groups, it is necessary to strictly abide by the relevant dangerous chemical transportation regulations, and the packaging should be tight to ensure no leakage. Transportation personnel also need to be familiar with their emergency handling measures, just in case. The transportation of thioglycolic acid must also strictly abide by the regulations on the transportation of hazardous chemicals. The packaging should comply with relevant standards. During transportation, it should be handled lightly to prevent package damage. Once leakage occurs, effective measures should be taken immediately to avoid polluting the environment and endangering personnel safety.
In short, when storing and transporting oxygen, amino and thioglycolic acid, it is necessary to keep an eye on its chemical properties, strictly abide by relevant rules, and take comprehensive precautions to ensure safety.

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