3-Amino-5-Chloro-4-Hydroxybenzenesulphonic Acid

Linshang Chemical

Specifications

HS Code

549496

Chemical Formula C6H6ClNO5S
Molar Mass 239.64 g/mol
Appearance Solid
Solubility In Water Soluble
Color Typically colorless to light - colored
Pka Value Relevant to its acidic groups
Boiling Point Decomposes before boiling
Melting Point High (specific value depends on purity)
Density Specific density data based on solid form
Ph In Solution Acidic

As an accredited 3-Amino-5-Chloro-4-Hydroxybenzenesulphonic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 3 - amino - 5 - chloro - 4 - hydroxybenzenesulphonic Acid packaged in a sealed plastic bag.
Storage 3 - Amino - 5 - chloro - 4 - hydroxybenzenesulphonic acid should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and incompatible substances. Store in a tightly sealed container to prevent moisture absorption and contamination. Avoid storing near strong oxidizing agents. Follow proper safety regulations for chemical storage.
Shipping 3 - amino - 5 - chloro - 4 - hydroxybenzenesulphonic acid should be shipped in well - sealed containers, protected from moisture and heat. Ensure compliance with hazardous chemical shipping regulations, and label clearly for safe transportation.
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3-Amino-5-Chloro-4-Hydroxybenzenesulphonic Acid 3-Amino-5-Chloro-4-Hydroxybenzenesulphonic Acid
General Information
Where to Buy 3-Amino-5-Chloro-4-Hydroxybenzenesulphonic Acid in China?
As a trusted 3-Amino-5-Chloro-4-Hydroxybenzenesulphonic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 3-Amino-5-Chloro-4-Hydroxybenzenesulphonic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-amino-5-chloro-4-hydroxybenzenesulphonic Acid?
3-Amino-5-chloro-4-hydroxybenzenesulfonic acid has a wide range of uses. In the dye industry, it can be called a key intermediate. It can be ingeniously converted into various colorful dyes through a series of delicate chemical reactions. This is because of its unique chemical structure, which gives it an indispensable role in building the molecular structure of dyes. The resulting dyes have bright color and good fastness, and are widely used in many fields such as fabric printing and dyeing. They can make fabrics show a brilliant color, and they are not easy to fade after many washes and light.
In the field of pharmaceutical chemistry, it is also of important value. With its specific chemical activity, it may participate in the synthesis of drug molecules. In the synthesis of some drugs with specific pharmacological activities, 3-amino-5-chloro-4-hydroxybenzenesulfonic acid is either used as a starting material or plays a role in key steps to help build molecular structures with precise pharmacological activities, and then provide effective drugs for the treatment of diseases.
In addition, it is also common in the preparation of some fine chemical products. The development and production of products such as special coatings and functional additives, this compound may have a significant impact on the performance of the product due to its special chemical properties. It can give coatings special adhesion, weather resistance, etc., or make additives have unique functions to meet the diverse needs of fine chemical products in different industrial fields.
What are the physical properties of 3-amino-5-chloro-4-hydroxybenzenesulphonic Acid?
3-Amino-5-chloro-4-hydroxybenzenesulfonic acid is one of the organic compounds. Its physical properties are quite important and are related to many practical applications.
The appearance of this compound is often in a solid form, mostly powdered, delicate and uniform. This form is easy to store and transport, and has significant convenience in industrial production and laboratory operations. The color is usually almost white. In the pure state, the color is pure and there is no variegation. If the color is deviated, it may suggest that there is a problem with its purity.
Melting point is also a key physical property. After experimental determination, its melting point is in a specific range, and the temperature range makes this compound realize the transition from solid to liquid under corresponding conditions. This property is of great significance for controlling the reaction conditions in the process of material processing and chemical synthesis.
In terms of solubility, it has different performances in specific solvents. In water, it has a certain solubility and can form a uniform dispersion system. This property is conducive to its participation in liquid-phase reactions in some chemical processes. In organic solvents, such as ethanol and acetone, the solubility also varies. This difference in solubility creates conditions for separation, purification and specific chemical reactions.
In addition, its density also has unique values. This value indicates that the mass of this compound per unit volume is an important parameter in terms of material measurement, reaction ratio, and product design.
These physical properties of 3-amino-5-chloro-4-hydroxybenzenesulfonic acid are an important foundation for research and application in the chemical industry, pharmaceutical fields, and materials science, and play a key role in promoting the development of related fields.
What are the chemical properties of 3-amino-5-chloro-4-hydroxybenzenesulphonic Acid?
3-Amino-5-chloro-4-hydroxybenzenesulfonic acid, an organic compound. Its chemical properties are unique and acidic. Its sulfonic acid group (-SO-H) can dissociate hydrogen ions in water, neutralize and react with bases to form corresponding salts.
From its structural perspective, amino groups (-NH2O) are alkaline and can react with acids under specific conditions or participate in reactions such as amidation. Hydroxyl groups (-OH) are also active and can undergo esterification reactions to form esters when interacting with acids.
Although the chlorine atom (-Cl) in this compound is relatively stable, under specific reagents and reaction conditions, it may be substituted, triggering nucleophilic substitution reaction, and the chlorine atom is replaced by other groups.
Furthermore, the benzene ring endows it with certain stability and conjugated system characteristics, which have an impact on its physical and chemical properties. The conjugated system makes the distribution of molecular electron clouds more uniform, or affects its spectral properties, which is of great significance in the field of organic synthesis and analysis.
Its chemical properties make it potentially useful in dyes, medicine and other fields. In the dye industry, its structural properties can be used to introduce chromogenic groups through chemical reactions to produce dyes with specific colors and properties; in the pharmaceutical field, or because of the reactive groups contained, they can interact with biological macromolecules and have potential biological activity. It has become a starting material or key intermediate for drug development.
What is the preparation method of 3-amino-5-chloro-4-hydroxybenzenesulphonic Acid?
The method of preparing 3-amino-5-chloro-4-hydroxybenzenesulfonic acid follows the following steps.
The starting material, take more suitable aromatic derivatives. With an aromatic hydrocarbon as the base, the method of chlorination is carried out first. In a specific reaction vessel, add aromatic hydrocarbons and an appropriate amount of chlorination reagents, such as chlorine gas or chlorine-containing compounds, complicate with a suitable catalyst, heat up and control the temperature in a specific interval, so that the chlorination reaction proceeds in an orderly manner. During the chlorination process, pay close attention to the progress of the reaction, and use a variety of analytical methods, such as chromatographic analysis, to monitor the formation of chlorinated products. When the chlorination reaction reaches the expected level, chlorine-containing aromatic derivatives are obtained.
Next, the hydroxyl group is introduced. This step is usually achieved by hydrolysis or other hydroxylation reactions. According to the selected reaction path, choose the appropriate reagent and conditions. If alkaline hydrolysis is used, a certain concentration of alkali solution needs to be prepared, and the chlorine-containing derivative is slowly added to react at a specific temperature and time. After the hydroxyl group is introduced, the molecular structure is initially formed.
Then, the step of sulfonation is performed. Take the product containing chlorine and hydroxyl groups and add a sulfonating agent, such as concentrated sulfuric acid or fuming sulfuric acid. At a suitable temperature and reaction environment, the sulfonating agent interacts with the substrate molecule, and the sulfonic acid group is connected to the benzene ring to form a 3-amino-5-chloro-4-hydroxybenzenesulfonic acid precursor.
Finally, the amination reaction is carried out. Appropriate amination reagents, such as ammonia or compounds containing amino groups, are selected in a specific reaction system to replace the groups in the corresponding positions with amino groups to obtain 3-amino-5-chloro-4-hydroxybenzenesulfonic acid. After the reaction is completed, the pure target product is obtained through separation, purification and other steps. Throughout the preparation process, the conditions of each step of the reaction are controlled to be the key, which is related to the purity and yield of the product.
3-amino-5-chloro-4-hydroxybenzenesulphonic Acid during storage and transportation
3-Amino-5-chloro-4-hydroxybenzenesulfonic acid, this is a fine chemical product. During storage and transportation, many matters need to be paid attention to.
The first thing to pay attention to is the temperature and humidity of the storage environment. This product should be stored in a cool and dry place to prevent moisture and deterioration. If the ambient humidity is too high, the moisture is easy to interact with it, or change its chemical properties, causing damage to the quality; if the temperature is too high, it may cause chemical reactions, and even risk safety.
Furthermore, the storage place should be well ventilated. Avoid mixing with oxidants, acids, alkalis and other substances. Due to its active chemical properties, contact with the above substances is prone to violent chemical reactions, or serious consequences such as combustion and explosion.
When transporting, the packaging must be sturdy. Make sure that the container is free of leakage to prevent the product from being scattered, lost, polluting the environment, and avoiding harm to transporters. Transportation vehicles should be selected with appropriate protective and emergency equipment.
And the transportation process should be smooth to avoid violent vibration and collision. Vibration and collision or damage to the packaging may also cause physical or chemical reactions of internal substances.
In addition, regardless of storage or transportation, relevant regulations and standards should be strictly adhered to. Operators need to undergo professional training and be familiar with product characteristics and safety precautions, so as to ensure the safety and quality of 3-amino-5-chloro-4-hydroxybenzenesulfonic acid during storage and transportation.