Linshang Chemical
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3-Benzoylchlorobenzene
Linshang Chemical
|
HS Code |
104797 |
| Chemical Formula | C13H9ClO |
| Molar Mass | 216.66 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 302 - 304 °C |
| Melting Point | 18 - 20 °C |
| Density | 1.24 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like benzene, toluene |
| Flash Point | 137 °C |
| Odor | Pungent odor |
| Cas Number | 2114-18-7 |
As an accredited 3-Benzoylchlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 3 - benzoylchlorobenzene packaged in a sealed, corrosion - resistant bottle. |
| Storage | 3 - Benzoylchlorobenzene should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, flames, and incompatible substances like strong oxidizers, bases, and moisture. Store in a tightly - sealed container to prevent leakage and exposure to air. This helps maintain its stability and reduces the risk of hazardous reactions. |
| Shipping | 3 - benzoylchlorobenzene is a chemical. It should be shipped in accordance with relevant hazardous materials regulations. Use proper packaging to prevent leakage, and ensure carriers are licensed to handle such chemicals during transportation. |
Competitive 3-Benzoylchlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
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What are the physical properties of 3-benzoyl chlorobenzene?
The physical properties of 3-octyl dodecyl alcohol ether octyl are inherent in the chemical industry, materials, and other fields.
This compound is often liquid, and under normal conditions, its outer surface is clear and transparent, or slightly colored. As far as the melting temperature is concerned, because the molecular phase is large and has a certain degree of carbon, the melting phase is low, mostly in the low temperature domain, and the boiling temperature is high, it needs to be high before it can be boiled. This property makes it useful in some systems that require a certain degree of resistance.
Its solubility is also special, because the molecule has both a hydrophobic alcohol ether group and a hydrophobic carbon alkyl group. It has good solubility in some solvents, such as alkanes and aromatic solvents. In the same way, water also has a certain degree of stability, and it can form an emulsion or disperse system under suitable conditions. This property is very important in the use of surface activity, emulsification, etc.
In addition, its density is slightly smaller or similar to that of water, with a certain degree of fluidity, and the fluidity is affected by the fluidity, and the fluidity increases, and the fluidity increases. In addition, its viscosity has a certain value under normal conditions, which is suitable for some processes that require specific fluidity. In terms of interfacial properties, because of its special fluidity, it can reduce the interfacial forces of liquid-liquid and liquid-solid, and play a role in the use of the interfacial phase, such as fluidity and defoaming.
This compound is often liquid, and under normal conditions, its outer surface is clear and transparent, or slightly colored. As far as the melting temperature is concerned, because the molecular phase is large and has a certain degree of carbon, the melting phase is low, mostly in the low temperature domain, and the boiling temperature is high, it needs to be high before it can be boiled. This property makes it useful in some systems that require a certain degree of resistance.
Its solubility is also special, because the molecule has both a hydrophobic alcohol ether group and a hydrophobic carbon alkyl group. It has good solubility in some solvents, such as alkanes and aromatic solvents. In the same way, water also has a certain degree of stability, and it can form an emulsion or disperse system under suitable conditions. This property is very important in the use of surface activity, emulsification, etc.
In addition, its density is slightly smaller or similar to that of water, with a certain degree of fluidity, and the fluidity is affected by the fluidity, and the fluidity increases, and the fluidity increases. In addition, its viscosity has a certain value under normal conditions, which is suitable for some processes that require specific fluidity. In terms of interfacial properties, because of its special fluidity, it can reduce the interfacial forces of liquid-liquid and liquid-solid, and play a role in the use of the interfacial phase, such as fluidity and defoaming.
What are the chemical properties of 3-benzoyl chlorobenzene?
The chemical properties of 3-bromoacrylonitrile bromonene are particularly important and are related to many chemical reaction uses. This substance has active chemical activity and has attracted much attention in the field of organic synthesis.
It has electrophilic substitution activity. Due to the existence of bromine atoms in the molecule, bromine atoms have strong electronegativity, which can make the carbon atoms connected to it partially positive and easily attract nucleophiles to attack. Therefore, in many nucleophilic substitution reactions, bromine atoms can be used as leaving groups to react with various nucleophiles such as alkoxides and amines, thereby forming new carbon-heteroatomic bonds and derived rich and diverse organic compounds, which are of key significance in drug synthesis and material preparation.
Furthermore, its carbon-carbon double bond also gives the substance the activity of addition reaction. Addition reactions can occur with hydrogen halide, halogen elementals, etc. As far as the addition of hydrogen halide is concerned, following the Markov rule, hydrogen atoms tend to be added to double-bonded carbon atoms containing more hydrogen to generate corresponding halogenated products. This reaction can achieve precise modification of molecular structures and expand the structural diversity of compounds.
In addition, 3-bromoacrylonitrile bromonene also has unique reaction properties due to the presence of cyanyl groups. Cyanyl groups can undergo hydrolysis to form carboxyl groups, or nucleophilic addition reactions with Grignard reagents, etc., further enriching their derivatization pathways and providing many possibilities for organic synthesis.
Due to its multiple active chemical properties, 3-bromoacrylonitrile-bromonene plays an indispensable role in the field of organic synthetic chemistry, providing an important material basis for the creation of new organic compounds and the exploration of novel synthetic methods.
It has electrophilic substitution activity. Due to the existence of bromine atoms in the molecule, bromine atoms have strong electronegativity, which can make the carbon atoms connected to it partially positive and easily attract nucleophiles to attack. Therefore, in many nucleophilic substitution reactions, bromine atoms can be used as leaving groups to react with various nucleophiles such as alkoxides and amines, thereby forming new carbon-heteroatomic bonds and derived rich and diverse organic compounds, which are of key significance in drug synthesis and material preparation.
Furthermore, its carbon-carbon double bond also gives the substance the activity of addition reaction. Addition reactions can occur with hydrogen halide, halogen elementals, etc. As far as the addition of hydrogen halide is concerned, following the Markov rule, hydrogen atoms tend to be added to double-bonded carbon atoms containing more hydrogen to generate corresponding halogenated products. This reaction can achieve precise modification of molecular structures and expand the structural diversity of compounds.
In addition, 3-bromoacrylonitrile bromonene also has unique reaction properties due to the presence of cyanyl groups. Cyanyl groups can undergo hydrolysis to form carboxyl groups, or nucleophilic addition reactions with Grignard reagents, etc., further enriching their derivatization pathways and providing many possibilities for organic synthesis.
Due to its multiple active chemical properties, 3-bromoacrylonitrile-bromonene plays an indispensable role in the field of organic synthetic chemistry, providing an important material basis for the creation of new organic compounds and the exploration of novel synthetic methods.
What are the common uses of 3-benzoyl chlorobenzene?
The common use of ethylene 3-valerynate is widely used in various fields of organic synthesis due to its unique chemical properties.
First, it can be a key intermediate in the synthesis of drugs. For example, it can be constructed through a series of reactions with specific biological activities. Taking the development of an anti-cancer drug as an example, ethylene 3-valerynate can participate in the formation of drug core skeletons. Through clever chemical reactions, the resulting compounds can target cancer cells and inhibit their proliferation. Its alkynyl group is active and can react with a variety of reagents containing active functional groups, thereby introducing the required structural fragments to achieve the original intention of drug design.
Second, it is also indispensable in the field of materials science. In the preparation of polymer materials with special properties, ethylene 3-valerynate can be used as a comonomer. Because the alkynyl group can participate in the polymerization reaction, it endows the polymer material with special properties. If a polymer with photoelectric properties is prepared, and it is introduced into the main chain or side chain of the polymer, the conjugate structure of the alkynyl group can affect the electron cloud distribution of the material, thereby improving the conductivity, fluorescence and other photoelectric properties of the material, which has potential application value in the fields of organic Light Emitting Diode and solar cells.
Third, it is an important substrate in the conventional reactions of organic synthetic chemistry. It is often involved in coupling reactions such as Sonogashira, in which the alkynyl group of ethyl 3-valerynate can be coupled with halogenated aromatics or halogenated olefins under palladium catalysis to form carbon-carbon bonds, thereby synthesizing a series of compounds with conjugated structures. Such compounds are widely used in the fragrance, dye and other industries, and can be used to synthesize novel perfume molecules with novel structures to endow products with unique aromas; or to synthesize new dyes to improve the color and stability of dyes.
First, it can be a key intermediate in the synthesis of drugs. For example, it can be constructed through a series of reactions with specific biological activities. Taking the development of an anti-cancer drug as an example, ethylene 3-valerynate can participate in the formation of drug core skeletons. Through clever chemical reactions, the resulting compounds can target cancer cells and inhibit their proliferation. Its alkynyl group is active and can react with a variety of reagents containing active functional groups, thereby introducing the required structural fragments to achieve the original intention of drug design.
Second, it is also indispensable in the field of materials science. In the preparation of polymer materials with special properties, ethylene 3-valerynate can be used as a comonomer. Because the alkynyl group can participate in the polymerization reaction, it endows the polymer material with special properties. If a polymer with photoelectric properties is prepared, and it is introduced into the main chain or side chain of the polymer, the conjugate structure of the alkynyl group can affect the electron cloud distribution of the material, thereby improving the conductivity, fluorescence and other photoelectric properties of the material, which has potential application value in the fields of organic Light Emitting Diode and solar cells.
Third, it is an important substrate in the conventional reactions of organic synthetic chemistry. It is often involved in coupling reactions such as Sonogashira, in which the alkynyl group of ethyl 3-valerynate can be coupled with halogenated aromatics or halogenated olefins under palladium catalysis to form carbon-carbon bonds, thereby synthesizing a series of compounds with conjugated structures. Such compounds are widely used in the fragrance, dye and other industries, and can be used to synthesize novel perfume molecules with novel structures to endow products with unique aromas; or to synthesize new dyes to improve the color and stability of dyes.
What is the preparation method of 3-benzoyl chlorobenzene?
3-The best way to make croton cream is to remove the croton kernels, remove the outer skin, take the kernels, and then apply the appropriate method.
First place the croton kernels on the layer, wrap it in a cloth, and use force to make the oil come out and absorb the oil. The method needs to be repeated many times to remove the oil from the croton until the croton kernels are frosted.
Or if there is a method of frying. Take the croton kernels first, put them in the middle, and fry them slowly. Fry them without turning them over, so that the taste is uniform. When the color of the croton kernels is deep, and the oil overflows, there is a burnt aroma, take it out and grind it into a powder, you can also get croton cream.
Then fry the croton cream, you need to carefully grasp the heat. When the heat is low, the oil cannot be removed, and the toxicity is not present; when the heat is high, the croton is easily charred and loses its durability.
If the croton cream is made by the method of cooking or frying, it needs to be properly stored to prevent it from absorbing moisture and losing its effectiveness. And croton cream is very toxic, and it should not be used if it is not used, so as not to endanger life.
First place the croton kernels on the layer, wrap it in a cloth, and use force to make the oil come out and absorb the oil. The method needs to be repeated many times to remove the oil from the croton until the croton kernels are frosted.
Or if there is a method of frying. Take the croton kernels first, put them in the middle, and fry them slowly. Fry them without turning them over, so that the taste is uniform. When the color of the croton kernels is deep, and the oil overflows, there is a burnt aroma, take it out and grind it into a powder, you can also get croton cream.
Then fry the croton cream, you need to carefully grasp the heat. When the heat is low, the oil cannot be removed, and the toxicity is not present; when the heat is high, the croton is easily charred and loses its durability.
If the croton cream is made by the method of cooking or frying, it needs to be properly stored to prevent it from absorbing moisture and losing its effectiveness. And croton cream is very toxic, and it should not be used if it is not used, so as not to endanger life.
What are the precautions for the storage and transportation of 3-benzoyl chlorobenzene?
3 - There are many points to be paid attention to in the storage and transportation of alum sulphur.
First, when storing, choose a dry, cool and well-ventilated place. Because alum sulphur is easily affected by moisture, if the storage environment is humid, it may undergo chemical reactions, resulting in quality damage. And it should be stored separately from other chemicals, especially those that can chemically react with it, such as some strong oxidizing agents, reducing agents, etc., to prevent accidental reactions. For example, if it coexists with strong oxidizing agents, it may cause violent oxidation reactions, and even the risk of fire and explosion.
Second, during transportation, be sure to ensure that the packaging is intact. Packaging materials should have good sealing and corrosion resistance to prevent leakage of alum sulphur. Transportation vehicles should also be kept clean and free of other debris or residues of substances that may react with them. At the same time, transportation personnel should be familiar with its characteristics and emergency treatment methods. If the packaging is accidentally damaged during transportation and there is a leakage, measures should be taken quickly, such as collecting and cleaning with suitable materials, to avoid its spread to the environment and cause pollution to the human body and the surrounding ecological environment. Moreover, the planning of transportation routes is also very important. It is necessary to avoid sensitive areas such as densely populated areas and water sources to reduce latent risks.
In short, whether it is storing or transporting alum sulphur, it needs to be treated with rigor and follow the corresponding norms and requirements to ensure its safety and stability.
First, when storing, choose a dry, cool and well-ventilated place. Because alum sulphur is easily affected by moisture, if the storage environment is humid, it may undergo chemical reactions, resulting in quality damage. And it should be stored separately from other chemicals, especially those that can chemically react with it, such as some strong oxidizing agents, reducing agents, etc., to prevent accidental reactions. For example, if it coexists with strong oxidizing agents, it may cause violent oxidation reactions, and even the risk of fire and explosion.
Second, during transportation, be sure to ensure that the packaging is intact. Packaging materials should have good sealing and corrosion resistance to prevent leakage of alum sulphur. Transportation vehicles should also be kept clean and free of other debris or residues of substances that may react with them. At the same time, transportation personnel should be familiar with its characteristics and emergency treatment methods. If the packaging is accidentally damaged during transportation and there is a leakage, measures should be taken quickly, such as collecting and cleaning with suitable materials, to avoid its spread to the environment and cause pollution to the human body and the surrounding ecological environment. Moreover, the planning of transportation routes is also very important. It is necessary to avoid sensitive areas such as densely populated areas and water sources to reduce latent risks.
In short, whether it is storing or transporting alum sulphur, it needs to be treated with rigor and follow the corresponding norms and requirements to ensure its safety and stability.
What are the main uses of 3-benzoyl chlorobenzene?
The main uses of 3-bromoacrylonitrile bromide are related to many fields of organic synthesis. It has made extraordinary contributions to the creation of delicate drug molecules in the path of medicinal chemistry.
In the grand landscape of drug research and development, 3-bromoacrylonitrile bromide can be used as a key intermediate. Through delicate chemical reaction planning, it can be cleverly combined with various active groups. In the long road of synthesis of some anti-cancer drugs, it participates in the construction of complex molecular structures with specific biological activities with its unique chemical activity. With the activity of its bromine atoms, key structural fragments can be precisely introduced. These fragments are like the "magic key" for the effectiveness of drugs, which can be closely matched with specific targets in cancer cells, and then effectively inhibit the growth and spread of cancer cells.
In the vast world of materials science, 3-bromoacrylonitrile bromide also plays a pivotal role. In the development of advanced functional materials, it is an indispensable and important raw material. Taking high-performance polymer materials as an example, when they are integrated into the polymerization reaction system, their special chemical structure can endow the polymer with novel characteristics. The presence of bromine atoms can optimize the thermal stability of materials, so that materials can still maintain their structure and properties in high temperature environments; or it can improve the electrical properties of materials, bringing new possibilities to the field of electronic devices, such as improving the insulation properties of materials or giving them special electrical conductivity, so as to meet the strict requirements of different electronic devices.
Furthermore, in the field of fine chemical manufacturing, 3-bromoacrylonitrile bromide is also a shining presence. In the synthesis of fine chemicals such as fragrances and dyes, it can introduce unique structures and functions to products by virtue of its own chemical properties. In the synthesis of fragrances, the special structure formed by its participation in the reaction may endow fragrances with unique aroma characteristics and create a unique fragrance experience; in the synthesis of dyes, the structural fragments it contributes may optimize the color, fastness and other key properties of dyes, making dyes more effective in textile, printing and dyeing industries.
In the grand landscape of drug research and development, 3-bromoacrylonitrile bromide can be used as a key intermediate. Through delicate chemical reaction planning, it can be cleverly combined with various active groups. In the long road of synthesis of some anti-cancer drugs, it participates in the construction of complex molecular structures with specific biological activities with its unique chemical activity. With the activity of its bromine atoms, key structural fragments can be precisely introduced. These fragments are like the "magic key" for the effectiveness of drugs, which can be closely matched with specific targets in cancer cells, and then effectively inhibit the growth and spread of cancer cells.
In the vast world of materials science, 3-bromoacrylonitrile bromide also plays a pivotal role. In the development of advanced functional materials, it is an indispensable and important raw material. Taking high-performance polymer materials as an example, when they are integrated into the polymerization reaction system, their special chemical structure can endow the polymer with novel characteristics. The presence of bromine atoms can optimize the thermal stability of materials, so that materials can still maintain their structure and properties in high temperature environments; or it can improve the electrical properties of materials, bringing new possibilities to the field of electronic devices, such as improving the insulation properties of materials or giving them special electrical conductivity, so as to meet the strict requirements of different electronic devices.
Furthermore, in the field of fine chemical manufacturing, 3-bromoacrylonitrile bromide is also a shining presence. In the synthesis of fine chemicals such as fragrances and dyes, it can introduce unique structures and functions to products by virtue of its own chemical properties. In the synthesis of fragrances, the special structure formed by its participation in the reaction may endow fragrances with unique aroma characteristics and create a unique fragrance experience; in the synthesis of dyes, the structural fragments it contributes may optimize the color, fastness and other key properties of dyes, making dyes more effective in textile, printing and dyeing industries.
What are the physical properties of 3-benzoyl chlorobenzene?
3-Bromo acrylonitrile bromine, its physical state is liquid, volatile, left in the air for a long time, or changes color. Its smell is pungent, and it is uncomfortable to smell.
Its density is greater than that of water. If it is mixed with water, it will sink underwater, and the two are insoluble. And its solubility is specific, soluble in organic solvents such as ethanol and ether. This is due to the principle of similarity and miscibility. Organic solvents and 3-bromo acrylonitrile bromine have structure and polarity.
3-bromo acrylonitrile bromine is flammable. In case of open flame or hot topic, it will ignite and the fire will be rapid. It can form an explosive mixture in the air, and it will explode in case of fire source, which is dangerous.
Its chemical activity is high, the bromine atom in the molecule is active, and it is easily replaced by nucleophilic reagents. If it reacts with sodium alcohol, the bromine atom is replaced by an alkoxy group to form ether compounds; the cyanyl group is also active and can participate in a variety of reactions, such as hydrolysis to form carboxylic acids and reduction to form amines. And 3-bromoacrylonitrile bromine has poor stability. It is easy to decompose at high temperature, light or contact with specific substances, and the decomposition products may be toxic and corrosive. Be careful when using it.
This substance is widely used in the field of organic synthesis due to its active chemistry and special physical properties. It can be used as an intermediate to prepare many complex compounds containing cyanide groups or bromine atoms. However, due to its toxicity, flammability, and explosive properties, it is necessary to operate in strict accordance with safety procedures, work in a well-ventilated place, and prepare protective equipment to prevent accidents.
Its density is greater than that of water. If it is mixed with water, it will sink underwater, and the two are insoluble. And its solubility is specific, soluble in organic solvents such as ethanol and ether. This is due to the principle of similarity and miscibility. Organic solvents and 3-bromo acrylonitrile bromine have structure and polarity.
3-bromo acrylonitrile bromine is flammable. In case of open flame or hot topic, it will ignite and the fire will be rapid. It can form an explosive mixture in the air, and it will explode in case of fire source, which is dangerous.
Its chemical activity is high, the bromine atom in the molecule is active, and it is easily replaced by nucleophilic reagents. If it reacts with sodium alcohol, the bromine atom is replaced by an alkoxy group to form ether compounds; the cyanyl group is also active and can participate in a variety of reactions, such as hydrolysis to form carboxylic acids and reduction to form amines. And 3-bromoacrylonitrile bromine has poor stability. It is easy to decompose at high temperature, light or contact with specific substances, and the decomposition products may be toxic and corrosive. Be careful when using it.
This substance is widely used in the field of organic synthesis due to its active chemistry and special physical properties. It can be used as an intermediate to prepare many complex compounds containing cyanide groups or bromine atoms. However, due to its toxicity, flammability, and explosive properties, it is necessary to operate in strict accordance with safety procedures, work in a well-ventilated place, and prepare protective equipment to prevent accidents.
What are the chemical properties of 3-benzoyl chlorobenzene?
3-Benzyl benzyl chloride, also known as α,α′ - dichlorodimethylbenzene, has unique chemical properties, let me list them in detail.
It has the typical properties of halogenated aromatics. Chlorine atoms are active and can cause many nucleophilic substitution reactions. In the case of alkali metal salts of alcohols, such as sodium ethyl alcohol, under appropriate conditions, the chlorine atoms are replaced by ethoxy groups and ether-generating compounds. This reaction mechanism is that the nucleophilic reagent ethanol root ion attacks the carbon atom connected to chlorine in benzyl chlorobenzyl chloride, and the chlorine leaves in the form of chloride ions to form a new carbon-oxygen bond. This is a classic\ (S_ {N} 2\) reaction process. The reaction conditions are mild, and appropriate solvents, such as\ (N, N -\) dimethylformamide (DMF), are required to help improve the activity of nucleophilic reagents.
Reaction with ammonia or amines is also a nucleophilic substitution. The nitrogen atom in ammonia has a lone pair of electrons and is the nucleophilic center. It attacks the carbon connected to the chlorine atom in benzyl chlorobenzyl chloride, and can generate amine derivatives through reaction. If ethylamine is used as nucleophilic reagent,\ (N -\) benzyl-\ (N -\) (chlorobenzyl) ethylamine can be obtained. This reaction can enrich the types of organic amine compounds and is of great value in drug synthesis and material intermediate preparation. The benzyl group of
benzyl chloride is structurally stable, but the electron cloud density on benzyl carbons decreases due to the electron-absorbing effect of chlorine atoms. Under the catalysis of Lewis acid such as aluminum trichloride, the alkylation reaction of Fu-g can occur. Using benzene as the reaction substrate, benzyl positive ions in benzyl chloride attack the benzene ring as an electrophilic reagent to form new carbon-carbon bonds to obtain dibenzylbenzene compounds. This reaction can expand the carbon skeleton of aromatic compounds, which is of great significance in the field of organic synthesis chemistry, and can construct complex polycyclic aromatic hydrocarbon structures.
In addition, it can also participate in the elimination reaction. Under the action of strong alkali alcohol potassium, chlorine atoms and hydrogen atoms on adjacent carbons are eliminated to form unsaturated olefin compounds. This reaction requires a high temperature and the solvent needs to be alcohol, which can prepare functional material intermediates with carbon-carbon double bonds.
In summary, 3-benzylchlorobenzyl chloride atoms coexist with benzyl structures, have active chemical properties, and can participate in various organic reactions. It is widely used in organic synthesis, chemical production and other fields. It is an important raw material for the preparation of various functional compounds.
It has the typical properties of halogenated aromatics. Chlorine atoms are active and can cause many nucleophilic substitution reactions. In the case of alkali metal salts of alcohols, such as sodium ethyl alcohol, under appropriate conditions, the chlorine atoms are replaced by ethoxy groups and ether-generating compounds. This reaction mechanism is that the nucleophilic reagent ethanol root ion attacks the carbon atom connected to chlorine in benzyl chlorobenzyl chloride, and the chlorine leaves in the form of chloride ions to form a new carbon-oxygen bond. This is a classic\ (S_ {N} 2\) reaction process. The reaction conditions are mild, and appropriate solvents, such as\ (N, N -\) dimethylformamide (DMF), are required to help improve the activity of nucleophilic reagents.
Reaction with ammonia or amines is also a nucleophilic substitution. The nitrogen atom in ammonia has a lone pair of electrons and is the nucleophilic center. It attacks the carbon connected to the chlorine atom in benzyl chlorobenzyl chloride, and can generate amine derivatives through reaction. If ethylamine is used as nucleophilic reagent,\ (N -\) benzyl-\ (N -\) (chlorobenzyl) ethylamine can be obtained. This reaction can enrich the types of organic amine compounds and is of great value in drug synthesis and material intermediate preparation. The benzyl group of
benzyl chloride is structurally stable, but the electron cloud density on benzyl carbons decreases due to the electron-absorbing effect of chlorine atoms. Under the catalysis of Lewis acid such as aluminum trichloride, the alkylation reaction of Fu-g can occur. Using benzene as the reaction substrate, benzyl positive ions in benzyl chloride attack the benzene ring as an electrophilic reagent to form new carbon-carbon bonds to obtain dibenzylbenzene compounds. This reaction can expand the carbon skeleton of aromatic compounds, which is of great significance in the field of organic synthesis chemistry, and can construct complex polycyclic aromatic hydrocarbon structures.
In addition, it can also participate in the elimination reaction. Under the action of strong alkali alcohol potassium, chlorine atoms and hydrogen atoms on adjacent carbons are eliminated to form unsaturated olefin compounds. This reaction requires a high temperature and the solvent needs to be alcohol, which can prepare functional material intermediates with carbon-carbon double bonds.
In summary, 3-benzylchlorobenzyl chloride atoms coexist with benzyl structures, have active chemical properties, and can participate in various organic reactions. It is widely used in organic synthesis, chemical production and other fields. It is an important raw material for the preparation of various functional compounds.
What are the synthesis methods of 3-benzoyl chlorobenzene?
The synthesis methods of 3-benzyl benzyl chloride are different, and each is based on ancient methods and modern techniques.
First, benzyl chloride is used as the starting material and obtained by halogenation reaction. In a suitable reaction vessel, benzyl chloride is placed, and an appropriate amount of catalyst is added, such as Lewis acid, common ones are aluminum trichloride, ferric chloride, etc. The temperature is controlled in an appropriate range, usually at tens of degrees Celsius, chlorine gas is introduced, and the chlorine gas undergoes a substitution reaction with benzyl chloride. The hydrogen atom on the benzyl group of benzyl chloride is replaced by the chlorine atom, and then 3-benzyl chloride is formed. This reaction needs to pay attention to the rate of chlorine gas introduction. If the rate is too fast, it is easy to cause the formation of multiple substitution products, which affects the purity of the target product.
Second, toluene is used as the starting material and is prepared by multi-step reaction. First, toluene and chlorine are subjected to side-chain chlorination reaction in the presence of light or initiator to obtain benzyl chloride. Then, the obtained benzyl chloride is halogenated as described above, and 3-benzyl benzyl chloride can also be obtained. Although this path is a little complicated, toluene raw materials are easy to obtain, and the cost may be advantageous.
There are also benzene and chloromethyl benzyl ether as raw materials. First, benzene and chloromethyl benzyl ether are reacted under the Friedel-Crafts reaction condition with anhydrous aluminum trichloride as a catalyst to generate benzyl phenyl ether intermediates. Then, the intermediate is properly converted, such as by a specific halogenating agent, to 3-benzyl benzyl chloride. This method requires fine control of the reaction conditions to ensure that the reaction proceeds according to the expected path.
Furthermore, with benzyl alcohol as the starting material, the benzyl alcohol is first converted into the corresponding halide, such as by reacting with hydrogen halide or halogenating reagents to obtain benzyl halides. Then, the benzyl halogen is further halogenated with a suitable halogenating reagent under the action of a catalyst, which can lead to the synthesis of 3-benzyl benzyl chloride. In this approach, the benzyl alcohol raw material is common and easy to obtain, and the reaction conditions are relatively mild, which has certain application value.
All kinds of synthesis methods have their own advantages and disadvantages. According to actual needs, many factors such as the availability of raw materials, cost, difficulty of reaction conditions, and purity of the product must be considered, and the best one should be selected.
First, benzyl chloride is used as the starting material and obtained by halogenation reaction. In a suitable reaction vessel, benzyl chloride is placed, and an appropriate amount of catalyst is added, such as Lewis acid, common ones are aluminum trichloride, ferric chloride, etc. The temperature is controlled in an appropriate range, usually at tens of degrees Celsius, chlorine gas is introduced, and the chlorine gas undergoes a substitution reaction with benzyl chloride. The hydrogen atom on the benzyl group of benzyl chloride is replaced by the chlorine atom, and then 3-benzyl chloride is formed. This reaction needs to pay attention to the rate of chlorine gas introduction. If the rate is too fast, it is easy to cause the formation of multiple substitution products, which affects the purity of the target product.
Second, toluene is used as the starting material and is prepared by multi-step reaction. First, toluene and chlorine are subjected to side-chain chlorination reaction in the presence of light or initiator to obtain benzyl chloride. Then, the obtained benzyl chloride is halogenated as described above, and 3-benzyl benzyl chloride can also be obtained. Although this path is a little complicated, toluene raw materials are easy to obtain, and the cost may be advantageous.
There are also benzene and chloromethyl benzyl ether as raw materials. First, benzene and chloromethyl benzyl ether are reacted under the Friedel-Crafts reaction condition with anhydrous aluminum trichloride as a catalyst to generate benzyl phenyl ether intermediates. Then, the intermediate is properly converted, such as by a specific halogenating agent, to 3-benzyl benzyl chloride. This method requires fine control of the reaction conditions to ensure that the reaction proceeds according to the expected path.
Furthermore, with benzyl alcohol as the starting material, the benzyl alcohol is first converted into the corresponding halide, such as by reacting with hydrogen halide or halogenating reagents to obtain benzyl halides. Then, the benzyl halogen is further halogenated with a suitable halogenating reagent under the action of a catalyst, which can lead to the synthesis of 3-benzyl benzyl chloride. In this approach, the benzyl alcohol raw material is common and easy to obtain, and the reaction conditions are relatively mild, which has certain application value.
All kinds of synthesis methods have their own advantages and disadvantages. According to actual needs, many factors such as the availability of raw materials, cost, difficulty of reaction conditions, and purity of the product must be considered, and the best one should be selected.
What should be paid attention to when storing and transporting 3-benzoyl chlorobenzene?
When storing and transporting 3-amyl decane ether, there are many key points to pay attention to.
First, the storage place must be kept cool, dry and well ventilated. This substance is quite sensitive to temperature and humidity, and high temperature and humid environment can easily cause its properties to change. Therefore, it should be chosen to stay away from heat sources and fire sources, and the humidity of the warehouse should be controlled within a reasonable range to prevent moisture dissolution and other conditions. As "Tiangong Kaiwu" states, all kinds of materials have their suitable storage places, and this is no exception.
Second, when transporting, the packaging must be tight and reliable. Choose packaging materials that meet the standards to ensure that there is no risk of leakage during transportation. Due to its chemical properties, once it leaks or causes environmental pollution, it may also endanger the safety of transporters. " In Tiangong Kaiwu, it is said that material handling, stable packaging is the first priority, and this principle is also applicable today.
Third, the storage and transportation process should strictly avoid contact with strong oxidants, strong acids, strong alkalis and other substances. 3-pentyl decane ether pentane is prone to chemical reactions with these substances, or serious consequences such as combustion and explosion. As "Tiangong Kaiwu" says, things of different physical properties cannot be mixed and transported at will, and they must be strictly guarded.
Fourth, the storage area and transportation tools should be equipped with corresponding fire protection and leakage emergency treatment equipment. In the event of an emergency, it can respond quickly and reduce losses. Although "Tiangong Kaiwu" does not describe such emergency equipment in detail, the awareness of handling emergencies is the same throughout history and today. Transport personnel and warehouse management personnel also need professional training, familiar with the characteristics of the substance and emergency treatment methods, so as to ensure the safety of storage and transportation process.
First, the storage place must be kept cool, dry and well ventilated. This substance is quite sensitive to temperature and humidity, and high temperature and humid environment can easily cause its properties to change. Therefore, it should be chosen to stay away from heat sources and fire sources, and the humidity of the warehouse should be controlled within a reasonable range to prevent moisture dissolution and other conditions. As "Tiangong Kaiwu" states, all kinds of materials have their suitable storage places, and this is no exception.
Second, when transporting, the packaging must be tight and reliable. Choose packaging materials that meet the standards to ensure that there is no risk of leakage during transportation. Due to its chemical properties, once it leaks or causes environmental pollution, it may also endanger the safety of transporters. " In Tiangong Kaiwu, it is said that material handling, stable packaging is the first priority, and this principle is also applicable today.
Third, the storage and transportation process should strictly avoid contact with strong oxidants, strong acids, strong alkalis and other substances. 3-pentyl decane ether pentane is prone to chemical reactions with these substances, or serious consequences such as combustion and explosion. As "Tiangong Kaiwu" says, things of different physical properties cannot be mixed and transported at will, and they must be strictly guarded.
Fourth, the storage area and transportation tools should be equipped with corresponding fire protection and leakage emergency treatment equipment. In the event of an emergency, it can respond quickly and reduce losses. Although "Tiangong Kaiwu" does not describe such emergency equipment in detail, the awareness of handling emergencies is the same throughout history and today. Transport personnel and warehouse management personnel also need professional training, familiar with the characteristics of the substance and emergency treatment methods, so as to ensure the safety of storage and transportation process.
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