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3-Chloro-3-Nitro Benzene Sulfonyl Chloride
Linshang Chemical
|
HS Code |
796186 |
| Chemical Formula | C6H3Cl2NO4S |
| Molecular Weight | 256.06 g/mol |
| Appearance | Solid (usually) |
| Physical State At Room Temperature | Solid |
| Odor | Pungent (likely) |
| Solubility In Water | Low (practically insoluble) |
| Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane |
| Melting Point | Data needed |
| Boiling Point | Data needed |
| Density | Data needed |
| Flash Point | Data needed |
| Hazard Class | Corrosive (due to sulfonyl chloride group), toxic (due to nitro group likely) |
As an accredited 3-Chloro-3-Nitro Benzene Sulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 3 - chloro - 3 - nitro benzene sulfonyl chloride in sealed chemical - grade containers. |
| Storage | 3 - Chloro - 3 - nitro benzene sulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture and air contact, as it may react with them. Store separately from incompatible substances like bases, reducing agents, and moisture - sensitive compounds to avoid hazardous reactions. |
| Shipping | 3 - chloro - 3 - nitro Benzene Sulfonyl Chloride is a hazardous chemical. It must be shipped in accordance with strict regulations, using proper packaging to prevent leakage, and transported by carriers licensed for such chemicals. |
Competitive 3-Chloro-3-Nitro Benzene Sulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 3-Chloro-3-Nitro Benzene Sulfonyl Chloride in China?
As a trusted 3-Chloro-3-Nitro Benzene Sulfonyl Chloride manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3-Chloro-3-Nitro Benzene Sulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 3-chloro-3-nitro Benzene Sulfonyl Chloride?
3-Chloro-3-nitrobenzenesulfonyl chloride is an important raw material for organic synthesis. It has a wide range of uses and is of key significance in many fields.
In the synthesis of medicine, it is often a key intermediate. The structure of guybenzenesulfonyl chloride can be introduced into specific functional groups through a series of reactions to construct complex drug molecular structures. With its reactivity, it can be substituted with various nucleophiles containing nitrogen and oxygen to prepare compounds with specific pharmacological activities.
In the process of pesticide creation, 3-chloro-3-nitrobenzenesulfonyl chloride also plays an important role. It can be used to synthesize new pesticides by changing their surrounding substituents, adjusting the physical and chemical properties of compounds, enhancing the activity and selectivity of pesticides to target organisms, and improving the effect and environmental adaptability of pesticides.
In the field of materials science, it can participate in the synthesis of polymer materials. React with compounds containing active hydrogen to form polymers with special properties. Such as preparing materials with specific electrical, optical or mechanical properties, providing new directions and possibilities for the development of materials science.
In addition, in the synthesis of dyes, it can be used as a starting material to build a color system of dye molecules through multi-step reactions, endowing dyes with unique colors and properties to meet different dyeing needs. In conclusion, 3-chloro-3-nitrobenzenesulfonyl chloride, with its unique chemical structure and reactivity, plays an indispensable role in many fields such as medicine, pesticides, materials, and dyes, providing an important material basis for technological innovation and development in various fields.
In the synthesis of medicine, it is often a key intermediate. The structure of guybenzenesulfonyl chloride can be introduced into specific functional groups through a series of reactions to construct complex drug molecular structures. With its reactivity, it can be substituted with various nucleophiles containing nitrogen and oxygen to prepare compounds with specific pharmacological activities.
In the process of pesticide creation, 3-chloro-3-nitrobenzenesulfonyl chloride also plays an important role. It can be used to synthesize new pesticides by changing their surrounding substituents, adjusting the physical and chemical properties of compounds, enhancing the activity and selectivity of pesticides to target organisms, and improving the effect and environmental adaptability of pesticides.
In the field of materials science, it can participate in the synthesis of polymer materials. React with compounds containing active hydrogen to form polymers with special properties. Such as preparing materials with specific electrical, optical or mechanical properties, providing new directions and possibilities for the development of materials science.
In addition, in the synthesis of dyes, it can be used as a starting material to build a color system of dye molecules through multi-step reactions, endowing dyes with unique colors and properties to meet different dyeing needs. In conclusion, 3-chloro-3-nitrobenzenesulfonyl chloride, with its unique chemical structure and reactivity, plays an indispensable role in many fields such as medicine, pesticides, materials, and dyes, providing an important material basis for technological innovation and development in various fields.
What are the physical properties of 3-chloro-3-nitro Benzene Sulfonyl Chloride
3-Chloro-3-nitrobenzenesulfonyl chloride, this material is quite unique in its properties. Its appearance is often crystalline, with pure white matter. Under the light, it shines brightly, like stars falling on the world. Its smell is pungent and its smell is frowning, but this is also one end of its physical properties.
When it comes to the melting point, the melting point is about a specific range. At this temperature, the state of solid and liquid gradually changes, and the movement of molecules also changes with the temperature. At the boiling point, vaporization and evaporation, molecules break free and escape into the air. In terms of solubility, in organic solvents, such as certain hydrocarbons, it is quite soluble, just like fish entering water and blending freely; however, in water, it is insoluble and difficult to mix, such as oil floating in water, and it is distinct. This is due to the characteristics of the molecular structure, which makes it different from different solvents.
The density is slightly heavier than that of ordinary liquids. When placed in a liquid, it often sinks to the bottom, like a stone entering water, and settles steadily. This physicality is relevant to its many applications, and it is also a must for those who handle it.
When it comes to the melting point, the melting point is about a specific range. At this temperature, the state of solid and liquid gradually changes, and the movement of molecules also changes with the temperature. At the boiling point, vaporization and evaporation, molecules break free and escape into the air. In terms of solubility, in organic solvents, such as certain hydrocarbons, it is quite soluble, just like fish entering water and blending freely; however, in water, it is insoluble and difficult to mix, such as oil floating in water, and it is distinct. This is due to the characteristics of the molecular structure, which makes it different from different solvents.
The density is slightly heavier than that of ordinary liquids. When placed in a liquid, it often sinks to the bottom, like a stone entering water, and settles steadily. This physicality is relevant to its many applications, and it is also a must for those who handle it.
What are the chemical properties of 3-chloro-3-nitro Benzene Sulfonyl Chloride
3-Chloro-3-nitrobenzenesulfonyl chloride, this is an organic compound. It has active chemical properties and has attracted much attention in the field of organic synthesis.
Looking at its structure, the chlorine atom and the nitro group are attached to the benzene ring, and the other contains a sulfonyl chloride group. Although the chlorine atom is an electron-absorbing group, it can reduce the electron cloud density of the benzene ring, but it is conjugated with the benzene ring and can participate in the nucleophilic substitution reaction under specific conditions. Nucleophiles can attack the carbon attached to the chlorine atom, and the chlorine atom leaves to form a new carbon-nucleophilic bond.
Nitro is a strong electron-absorbing group, which greatly reduces the electron cloud density of the benzene ring, reduces the electrophilic substitution activity of the benzene ring, but enhances the nucleophilicity of the adjacent and para-carbon atoms, which is conducive to the attack of nucleophilic reagents.
The sulfonyl chloride group is chemically active and easily hydrolyzed in contact with water to generate the corresponding sulfonic acid and hydrogen chloride. When it interacts with nucleophilic reagents such as alcohols and amines, it can undergo nucleophilic substitution reactions to form sulfonamides, sulfonates and other compounds.
In organic synthesis, 3-chloro-3-nitrobenzenesulfonyl chloride can be used as an important Through the reaction of different groups, various and complex organic molecular structures can be constructed, which have potential applications in medicinal chemistry, materials science and other fields.
Looking at its structure, the chlorine atom and the nitro group are attached to the benzene ring, and the other contains a sulfonyl chloride group. Although the chlorine atom is an electron-absorbing group, it can reduce the electron cloud density of the benzene ring, but it is conjugated with the benzene ring and can participate in the nucleophilic substitution reaction under specific conditions. Nucleophiles can attack the carbon attached to the chlorine atom, and the chlorine atom leaves to form a new carbon-nucleophilic bond.
Nitro is a strong electron-absorbing group, which greatly reduces the electron cloud density of the benzene ring, reduces the electrophilic substitution activity of the benzene ring, but enhances the nucleophilicity of the adjacent and para-carbon atoms, which is conducive to the attack of nucleophilic reagents.
The sulfonyl chloride group is chemically active and easily hydrolyzed in contact with water to generate the corresponding sulfonic acid and hydrogen chloride. When it interacts with nucleophilic reagents such as alcohols and amines, it can undergo nucleophilic substitution reactions to form sulfonamides, sulfonates and other compounds.
In organic synthesis, 3-chloro-3-nitrobenzenesulfonyl chloride can be used as an important Through the reaction of different groups, various and complex organic molecular structures can be constructed, which have potential applications in medicinal chemistry, materials science and other fields.
What is the preparation method of 3-chloro-3-nitro Benzene Sulfonyl Chloride
The method of preparing 3-chloro-3-nitrobenzenesulfonyl chloride is particularly particular. The first step is to carefully select the raw materials, and high-purity chlorobenzene must be used as the starting material. This is the foundation. Chlorobenzene needs to go through a refining process to remove impurities to ensure a smooth subsequent reaction.
Then, the nitrification reaction is carried out. The refined chlorobenzene is placed in a corrosion-resistant reactor, and a carefully prepared mixed acid (a mixture of nitric acid and sulfuric acid) is slowly injected. This process requires strict temperature control, often maintained in the low temperature range, about 0 to 10 degrees Celsius. Due to high temperature, side reactions are prone to occur, resulting in impure products. Mixing must be uniform, so that the chlorobenzene is in full contact with the mixed acid. After a few hours of reaction, 3-chloro-nitrobenzene can be obtained.
Then, the sulfonyl chloride reaction. Move 3-chloro-nitrobenzene to another clean reactor and add an appropriate amount of chlorosulfonic acid, which is the key reagent for sulfonation. The reaction temperature should be gradually raised to 50 to 70 degrees Celsius, and the reaction should be continuously stirred at this temperature. During this period, pay close attention to the reaction process and use instruments to detect the degree of reaction. When the reaction is complete, slowly drop in sulfoxide chloride, which is an essential agent for chlorination. Add it dropwise at a slow rate to prevent overreaction. Add it dropwise and raise it to 80 to 100 degrees Celsius for a few days to make the reaction complete. The
reaction has been completed, and the product needs to be post-processed. First, the reaction is quenched with an appropriate amount of ice water to cool the system and decompose the unreacted reagents. Then, the extraction method is carried out, and the product is extracted with a suitable organic solvent (such as dichloromethane). The extraction solution is dried with anhydrous sodium sulfate to remove the water in it. Then, the organic solvent is removed by vacuum distillation to obtain a crude product. The crude product is recrystallized by a method of recrystallization, recrystallized with a suitable solvent (such as a mixed solvent of ethanol and water), and the temperature and solvent dosage are carefully controlled to obtain a high-purity 3-chloro-3-nitrobenzenesulfonyl chloride. Every step needs to be handled carefully and must not be sloppy to obtain high-quality products.
Then, the nitrification reaction is carried out. The refined chlorobenzene is placed in a corrosion-resistant reactor, and a carefully prepared mixed acid (a mixture of nitric acid and sulfuric acid) is slowly injected. This process requires strict temperature control, often maintained in the low temperature range, about 0 to 10 degrees Celsius. Due to high temperature, side reactions are prone to occur, resulting in impure products. Mixing must be uniform, so that the chlorobenzene is in full contact with the mixed acid. After a few hours of reaction, 3-chloro-nitrobenzene can be obtained.
Then, the sulfonyl chloride reaction. Move 3-chloro-nitrobenzene to another clean reactor and add an appropriate amount of chlorosulfonic acid, which is the key reagent for sulfonation. The reaction temperature should be gradually raised to 50 to 70 degrees Celsius, and the reaction should be continuously stirred at this temperature. During this period, pay close attention to the reaction process and use instruments to detect the degree of reaction. When the reaction is complete, slowly drop in sulfoxide chloride, which is an essential agent for chlorination. Add it dropwise at a slow rate to prevent overreaction. Add it dropwise and raise it to 80 to 100 degrees Celsius for a few days to make the reaction complete. The
reaction has been completed, and the product needs to be post-processed. First, the reaction is quenched with an appropriate amount of ice water to cool the system and decompose the unreacted reagents. Then, the extraction method is carried out, and the product is extracted with a suitable organic solvent (such as dichloromethane). The extraction solution is dried with anhydrous sodium sulfate to remove the water in it. Then, the organic solvent is removed by vacuum distillation to obtain a crude product. The crude product is recrystallized by a method of recrystallization, recrystallized with a suitable solvent (such as a mixed solvent of ethanol and water), and the temperature and solvent dosage are carefully controlled to obtain a high-purity 3-chloro-3-nitrobenzenesulfonyl chloride. Every step needs to be handled carefully and must not be sloppy to obtain high-quality products.
What are the precautions for 3-chloro-3-nitro Benzene Sulfonyl Chloride in storage and transportation?
3-Chloro-3-nitrobenzenesulfonyl chloride requires careful attention during storage and transportation.
When storing, choose the first environment. Be sure to find a cool, dry and well-ventilated place to avoid high temperatures and open flames. Due to its chemical activity, high temperatures or open flames can easily cause violent reactions and cause dangerous emergencies.
Furthermore, storage should strictly abide by the principle of isolation. 3-Chloro-3-nitrobenzenesulfonyl chloride cannot be co-stored with bases, alcohols and strong reducing agents. Contact with these substances may cause chemical reactions, or cause disasters such as combustion and explosion.
Packaging must be tight and sturdy. Choose the appropriate packaging material to ensure that there is no risk of leakage. Once leaked, it will not only damage the substance itself, but also pollute the environment and endanger the safety of surrounding personnel.
As for transportation, personnel must undergo professional training and be familiar with its physical and chemical properties, hazard characteristics and emergency response methods. Transportation tools must also meet safety standards and be equipped with corresponding fire and leakage emergency equipment.
During driving, drive steadily and slowly to avoid emergency brakes and severe bumps, and prevent package damage and leakage. In case of bad weather, such as heavy rain and high temperature, proper protective measures need to be taken, or transportation should be suspended.
Transportation route planning is also critical, avoid densely populated areas and traffic arteries, and reduce hazards in the event of an accident.
In summary, the storage and transportation of 3-chloro-3-nitrobenzenesulfonyl chloride should be carried out in accordance with regulations, and must not be slack to ensure the safety of personnel and the environment.
When storing, choose the first environment. Be sure to find a cool, dry and well-ventilated place to avoid high temperatures and open flames. Due to its chemical activity, high temperatures or open flames can easily cause violent reactions and cause dangerous emergencies.
Furthermore, storage should strictly abide by the principle of isolation. 3-Chloro-3-nitrobenzenesulfonyl chloride cannot be co-stored with bases, alcohols and strong reducing agents. Contact with these substances may cause chemical reactions, or cause disasters such as combustion and explosion.
Packaging must be tight and sturdy. Choose the appropriate packaging material to ensure that there is no risk of leakage. Once leaked, it will not only damage the substance itself, but also pollute the environment and endanger the safety of surrounding personnel.
As for transportation, personnel must undergo professional training and be familiar with its physical and chemical properties, hazard characteristics and emergency response methods. Transportation tools must also meet safety standards and be equipped with corresponding fire and leakage emergency equipment.
During driving, drive steadily and slowly to avoid emergency brakes and severe bumps, and prevent package damage and leakage. In case of bad weather, such as heavy rain and high temperature, proper protective measures need to be taken, or transportation should be suspended.
Transportation route planning is also critical, avoid densely populated areas and traffic arteries, and reduce hazards in the event of an accident.
In summary, the storage and transportation of 3-chloro-3-nitrobenzenesulfonyl chloride should be carried out in accordance with regulations, and must not be slack to ensure the safety of personnel and the environment.
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