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3-Chloro-4-(Dimethylamino)Benzenediazonium Hexafluorophosphate
Linshang Chemical
|
HS Code |
664888 |
| Name | 3-Chloro-4-(Dimethylamino)Benzenediazonium Hexafluorophosphate |
| Chemical Formula | C8H10ClF6N3P |
| Molecular Weight | 333.60 g/mol |
| Appearance | Typically a solid |
| Solubility | Solubility characteristics depend on solvent, may be soluble in some organic solvents |
| Melting Point | Specific melting point data would need to be sourced from literature |
| Stability | Diazonium salts can be unstable, especially upon heating or in contact with certain substances |
| Reactivity | Reactive in diazo-coupling reactions |
| Hazard Class | May be classified as hazardous due to the diazonium group's potential reactivity |
As an accredited 3-Chloro-4-(Dimethylamino)Benzenediazonium Hexafluorophosphate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 3 - chloro - 4 - (dimethylamino)benzenediazonium Hexafluorophosphate in sealed chemical - grade package. |
| Storage | 3 - Chloro - 4 - (dimethylamino)benzenediazonium hexafluorophosphate should be stored in a cool, dry place, away from heat and direct sunlight. Keep it in a well - ventilated area, isolated from incompatible substances like reducing agents, combustibles, and strong bases. Store in a tightly - sealed container to prevent moisture absorption and potential decomposition. |
| Shipping | 3 - Chloro - 4 - (dimethylamino)benzenediazonium hexafluorophosphate is shipped in well - sealed, corrosion - resistant containers. It's transported under conditions that avoid heat, moisture, and shock to ensure safety during transit. |
Competitive 3-Chloro-4-(Dimethylamino)Benzenediazonium Hexafluorophosphate prices that fit your budget—flexible terms and customized quotes for every order.
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What are the chemical properties of 3-chloro-4- (dimethylamino) benzenediazonium Hexafluorophosphate
3-Chloro-4- (dimethylamino) benzene diazo hexafluorophosphate, this is an organic compound. Its chemical properties are unique, and some of the diazo salts are active and have high reactivity. Under suitable conditions, diazo groups can undergo various reactions, such as coupling reactions, which can be connected with many compounds containing active hydrogen to form novel organic structures. This property is widely used in the field of organic synthesis and is often used to construct complex organic molecules.
In this compound, chlorine atoms are used as substituents to participate in nucleophilic substitution reactions. Because chlorine atoms have certain electronegativity, they can change the density distribution of electron clouds in the benzene ring, affecting the reactivity and selectivity. The dimethylamino group is the power supply group, which can enhance the electron cloud density of the benzene ring, making the benzene ring more vulnerable to electrophilic attack.
Furthermore, hexafluorophosphate ions are relatively stable and form ionic pairs with diazonium cations, which affect the solubility and stability of the compound. Generally speaking, such diazonium salts have poor stability in the dry state, are easily decomposed by heat or impact, release nitrogen gas and produce highly active intermediates, triggering various chemical reactions. Therefore, careful operation is required when storing and using, and they are often stored in low temperature and dark environments to ensure experimental safety and controlled reactions.
In this compound, chlorine atoms are used as substituents to participate in nucleophilic substitution reactions. Because chlorine atoms have certain electronegativity, they can change the density distribution of electron clouds in the benzene ring, affecting the reactivity and selectivity. The dimethylamino group is the power supply group, which can enhance the electron cloud density of the benzene ring, making the benzene ring more vulnerable to electrophilic attack.
Furthermore, hexafluorophosphate ions are relatively stable and form ionic pairs with diazonium cations, which affect the solubility and stability of the compound. Generally speaking, such diazonium salts have poor stability in the dry state, are easily decomposed by heat or impact, release nitrogen gas and produce highly active intermediates, triggering various chemical reactions. Therefore, careful operation is required when storing and using, and they are often stored in low temperature and dark environments to ensure experimental safety and controlled reactions.
What are the common uses of 3-chloro-4- (dimethylamino) benzenediazonium Hexafluorophosphate
3-Chloro-4- (dimethylamino) benzene diazohexafluorophosphate is a key reagent in organic synthesis. Its common uses mainly cover the following ends:
First, it plays an important role in coupling reactions. It can couple with many electron-rich aromatic compounds, such as phenols, aromatic amines, etc., to form azo compounds with special structures. These azo compounds are of great significance in the dye industry. They can be used as key intermediates in the synthesis of a variety of bright and firm dyes, imparting brilliant colors to fabrics, leather and other materials.
Second, this reagent can be used to prepare aromatic amine compounds with special structures. Through the conversion reaction of diazo groups, under specific conditions, diazo groups can be replaced by other groups, such as hydrogen atoms, hydroxyl groups, cyanyl groups, etc., to obtain a series of aromatic amine derivatives with unique structures, which provide important synthetic building blocks for pharmaceutical chemistry, materials science and other fields.
Third, it also has applications in material surface modification. By reacting with active groups on the surface of materials, diazo salts can introduce specific functional groups on the surface of materials to improve the surface properties of materials, such as hydrophilicity and biocompatibility. It is widely used in surface modification of polymer materials, metal materials, etc.
Fourth, in the field of photochemistry, 3-chloro-4- (dimethylamino) benzodiazepine hexafluorophosphate can be used as a photoinitiator. Under light conditions, diazo groups decompose to produce free radicals, which in turn trigger a series of photochemical reactions, which play an indispensable role in photopolymerization, photolithography and other technologies.
First, it plays an important role in coupling reactions. It can couple with many electron-rich aromatic compounds, such as phenols, aromatic amines, etc., to form azo compounds with special structures. These azo compounds are of great significance in the dye industry. They can be used as key intermediates in the synthesis of a variety of bright and firm dyes, imparting brilliant colors to fabrics, leather and other materials.
Second, this reagent can be used to prepare aromatic amine compounds with special structures. Through the conversion reaction of diazo groups, under specific conditions, diazo groups can be replaced by other groups, such as hydrogen atoms, hydroxyl groups, cyanyl groups, etc., to obtain a series of aromatic amine derivatives with unique structures, which provide important synthetic building blocks for pharmaceutical chemistry, materials science and other fields.
Third, it also has applications in material surface modification. By reacting with active groups on the surface of materials, diazo salts can introduce specific functional groups on the surface of materials to improve the surface properties of materials, such as hydrophilicity and biocompatibility. It is widely used in surface modification of polymer materials, metal materials, etc.
Fourth, in the field of photochemistry, 3-chloro-4- (dimethylamino) benzodiazepine hexafluorophosphate can be used as a photoinitiator. Under light conditions, diazo groups decompose to produce free radicals, which in turn trigger a series of photochemical reactions, which play an indispensable role in photopolymerization, photolithography and other technologies.
What is the synthesis method of 3-chloro-4- (dimethylamino) benzenediazonium Hexafluorophosphate
The synthesis of 3-chloro-4- (dimethylamino) benzodiazo hexafluorophosphate is an important topic in the field of organic synthesis. Its synthesis is often achieved through a multi-step reaction.
The first step is usually 3-chloro-4- (dimethylamino) aniline as the starting material. This aniline compound is diazotized with sodium nitrite in a low temperature and strongly acidic medium. At low temperatures (about 0-5 ° C), the aqueous solution of sodium nitrite is slowly dropped into a mixture of 3-chloro-4- (dimethylamino) aniline and inorganic acids (such as hydrochloric acid or sulfuric acid). This process requires strict temperature control to prevent the decomposition of diazonium salts. The key to the diazotization reaction lies in the formation of nitrous acid and the reaction of aniline to form unstable diazonium intermediates.
The second step, after the formation of diazonium intermediates, needs to be combined with hexafluorophosphate ions. Usually an aqueous solution of hexafluorophosphoric acid or its salts is added to the reaction system containing diazonium salts. Hexafluorophosphate ions and diazonium cations undergo a metathesis reaction to form 3-chloro-4- (dimethylamino) benzodiazohexafluorophosphate precipitation. This precipitation can be obtained through appropriate separation and purification methods, such as filtration, washing, drying, etc., to obtain a pure target product.
However, the synthesis process also poses challenges. Diazonium salts are extremely unstable and easily decompose under heat, light or vibration, so the whole reaction process needs to be operated under low temperature, dark and mild conditions. At the same time, the purity, dosage of reagents involved in the reaction, reaction time, temperature and other parameters have a great impact on the yield and purity of the product, and need to be fine-tuned to obtain satisfactory synthesis results.
The first step is usually 3-chloro-4- (dimethylamino) aniline as the starting material. This aniline compound is diazotized with sodium nitrite in a low temperature and strongly acidic medium. At low temperatures (about 0-5 ° C), the aqueous solution of sodium nitrite is slowly dropped into a mixture of 3-chloro-4- (dimethylamino) aniline and inorganic acids (such as hydrochloric acid or sulfuric acid). This process requires strict temperature control to prevent the decomposition of diazonium salts. The key to the diazotization reaction lies in the formation of nitrous acid and the reaction of aniline to form unstable diazonium intermediates.
The second step, after the formation of diazonium intermediates, needs to be combined with hexafluorophosphate ions. Usually an aqueous solution of hexafluorophosphoric acid or its salts is added to the reaction system containing diazonium salts. Hexafluorophosphate ions and diazonium cations undergo a metathesis reaction to form 3-chloro-4- (dimethylamino) benzodiazohexafluorophosphate precipitation. This precipitation can be obtained through appropriate separation and purification methods, such as filtration, washing, drying, etc., to obtain a pure target product.
However, the synthesis process also poses challenges. Diazonium salts are extremely unstable and easily decompose under heat, light or vibration, so the whole reaction process needs to be operated under low temperature, dark and mild conditions. At the same time, the purity, dosage of reagents involved in the reaction, reaction time, temperature and other parameters have a great impact on the yield and purity of the product, and need to be fine-tuned to obtain satisfactory synthesis results.
3-Chloro-4- (dimethylamino) benzenediazonium Hexafluorophosphate during storage and transportation
3-Chloro-4- (dimethylamino) benzodiazepine hexafluorophosphate This material requires attention to many matters during storage and transportation.
Its properties are unstable, and it is easy to cause violent decomposition and even explosion when heated or hit. Therefore, when storing, when placed in a cool, well-ventilated place, and the temperature should be strictly controlled, away from fire and heat sources, and must not be mixed with flammable, flammable and reducing substances to prevent dangerous interactions.
During transportation, be sure to ensure that the packaging is intact and the loading is safe. The means of transportation used should be clean, dry, and away from fire sources and high temperature environments. Escorts must also be familiar with the characteristics of this object and emergency treatment methods, and always pay attention during transportation to avoid bumps, vibrations and collisions.
In addition, because of its certain toxicity, protective measures are indispensable during operation and contact. Such as wearing appropriate protective gloves, protective glasses and gas masks to prevent poisoning hazards caused by inhalation, ingestion or skin contact. In the event of an accident such as leakage, personnel should be evacuated quickly and access should be strictly restricted. Emergency responders should wear professional protective equipment and properly handle it according to scientific methods. Do not panic. In this way, the safety of storage and transportation can be guaranteed.
Its properties are unstable, and it is easy to cause violent decomposition and even explosion when heated or hit. Therefore, when storing, when placed in a cool, well-ventilated place, and the temperature should be strictly controlled, away from fire and heat sources, and must not be mixed with flammable, flammable and reducing substances to prevent dangerous interactions.
During transportation, be sure to ensure that the packaging is intact and the loading is safe. The means of transportation used should be clean, dry, and away from fire sources and high temperature environments. Escorts must also be familiar with the characteristics of this object and emergency treatment methods, and always pay attention during transportation to avoid bumps, vibrations and collisions.
In addition, because of its certain toxicity, protective measures are indispensable during operation and contact. Such as wearing appropriate protective gloves, protective glasses and gas masks to prevent poisoning hazards caused by inhalation, ingestion or skin contact. In the event of an accident such as leakage, personnel should be evacuated quickly and access should be strictly restricted. Emergency responders should wear professional protective equipment and properly handle it according to scientific methods. Do not panic. In this way, the safety of storage and transportation can be guaranteed.
What are the effects of 3-chloro-4- (dimethylamino) benzenediazonium Hexafluorophosphate on the environment and human health?
3-Chloro-4- (dimethylamino) benzodiazepine hexafluorophosphate This substance has an important impact on the environment and human health.
Looking at the environment, if this chemical substance is accidentally released outside, it may cause harm in many ways. First, in the soil, it may change the chemical composition of the soil, hinder the uptake of nutrients by plant roots, cause plant growth to be trapped, stunted, and affect the vegetation community of the ecosystem. Second, after flowing into the water body, it can harm aquatic organisms. Or change the chemical properties of the water body, cause changes in indicators such as pH and dissolved oxygen in the water body, endanger the survival of aquatic organisms such as fish and shellfish, and disrupt the aquatic ecological balance. Third, in the atmospheric environment, although its volatilization probability may be low, if it enters the atmosphere through special routes or participates in photochemical reactions, it will have adverse effects on atmospheric quality and even affect the regional climate.
As for human health, there are also many potential threats. If the human body inhales this substance through the respiratory tract, it can cause irritation to the respiratory mucosa, cause symptoms such as cough, asthma, breathing difficulties, and long-term exposure or cause chronic respiratory diseases. If exposed to the skin, it may cause skin allergies, redness, swelling, itching, and in severe cases, there may be a risk of burns, which may damage the skin's barrier function. If ingested inadvertently, it will damage the digestive system, or cause nausea, vomiting, abdominal pain, diarrhea, etc., and even affect the liver and kidney functions, endangering life. Therefore, when manufacturing, using, and disposing of 3-chloro-4- (dimethylamino) benzodiazepine hexafluorophosphate, great care must be taken to follow strict operating procedures and safety guidelines in order to reduce its harm to the environment and human health.
Looking at the environment, if this chemical substance is accidentally released outside, it may cause harm in many ways. First, in the soil, it may change the chemical composition of the soil, hinder the uptake of nutrients by plant roots, cause plant growth to be trapped, stunted, and affect the vegetation community of the ecosystem. Second, after flowing into the water body, it can harm aquatic organisms. Or change the chemical properties of the water body, cause changes in indicators such as pH and dissolved oxygen in the water body, endanger the survival of aquatic organisms such as fish and shellfish, and disrupt the aquatic ecological balance. Third, in the atmospheric environment, although its volatilization probability may be low, if it enters the atmosphere through special routes or participates in photochemical reactions, it will have adverse effects on atmospheric quality and even affect the regional climate.
As for human health, there are also many potential threats. If the human body inhales this substance through the respiratory tract, it can cause irritation to the respiratory mucosa, cause symptoms such as cough, asthma, breathing difficulties, and long-term exposure or cause chronic respiratory diseases. If exposed to the skin, it may cause skin allergies, redness, swelling, itching, and in severe cases, there may be a risk of burns, which may damage the skin's barrier function. If ingested inadvertently, it will damage the digestive system, or cause nausea, vomiting, abdominal pain, diarrhea, etc., and even affect the liver and kidney functions, endangering life. Therefore, when manufacturing, using, and disposing of 3-chloro-4- (dimethylamino) benzodiazepine hexafluorophosphate, great care must be taken to follow strict operating procedures and safety guidelines in order to reduce its harm to the environment and human health.
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