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3-Chloro-4-Methoxybenzenemethanamine
Linshang Chemical
|
HS Code |
274194 |
| Name | 3-Chloro-4-Methoxybenzenemethanamine |
| Chemical Formula | C8H10ClNO |
| Molar Mass | 171.62 g/mol |
| Appearance | Typically a solid or viscous liquid (no exact color data provided) |
| Solubility In Water | Poorly soluble (aromatic amines generally have low water solubility) |
| Boiling Point | No exact data, but likely higher due to intermolecular forces |
| Melting Point | No exact data available |
| Odor | May have an amine - like odor |
| Density | No exact value available |
| Flash Point | No exact data |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 3-Chloro-4-Methoxybenzenemethanamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 3 - chloro - 4 - methoxybenzenemethanamine in a sealed, labeled chemical container. |
| Storage | 3 - Chloro - 4 - methoxybenzenemethanamine should be stored in a cool, dry, and well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent leakage and exposure to air and moisture. Store it separately from oxidizing agents and acids to avoid potential chemical reactions. Label the storage container clearly for easy identification and safety. |
| Shipping | 3 - Chloro - 4 - methoxybenzenemethanamine is a chemical. Shipping should follow strict regulations. It must be properly packaged in corrosion - resistant containers, labeled clearly, and transported by carriers compliant with hazardous chemical shipping rules. |
Competitive 3-Chloro-4-Methoxybenzenemethanamine prices that fit your budget—flexible terms and customized quotes for every order.
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What is the chemical structure of 3-chloro-4-methoxybenzenemethanamine?
3 - chloro - 4 - methoxybenzenemethanamine, this is the name of an organic compound. According to its name, its chemical structure can be deduced as follows:
The compound is based on a benzene ring. Above the benzene ring, there is a chloro atom (chloro -) at the third position, and a methoxy group (methoxy -) at the fourth position. And "benzenemethanamine" shows that there is also a methylene (-CH 2O -) attached to the benzene ring, which is in turn connected to an amino group (-NH 2O).
In ancient words, its structure can be described as: benzene ring, organic base. In the position of No. 3, the chlorine atom is attached; in the position of No. 4, the methoxy group is attached. And there are methylene groups, which come out of the benzene ring and are complex with amino groups. This makes it a 3-chloro-4-methoxybenzenemethanamine structure. Among its structures, the benzene ring has aromatic properties, and the chlorine atom, methoxy group and amino group have their own properties, which affect each other, so that the compound has unique chemical properties. The structure is established, and it has a specific reaction path and activity in the chemical reaction, or due to the dislocation of each group, electronic effects, etc.
The compound is based on a benzene ring. Above the benzene ring, there is a chloro atom (chloro -) at the third position, and a methoxy group (methoxy -) at the fourth position. And "benzenemethanamine" shows that there is also a methylene (-CH 2O -) attached to the benzene ring, which is in turn connected to an amino group (-NH 2O).
In ancient words, its structure can be described as: benzene ring, organic base. In the position of No. 3, the chlorine atom is attached; in the position of No. 4, the methoxy group is attached. And there are methylene groups, which come out of the benzene ring and are complex with amino groups. This makes it a 3-chloro-4-methoxybenzenemethanamine structure. Among its structures, the benzene ring has aromatic properties, and the chlorine atom, methoxy group and amino group have their own properties, which affect each other, so that the compound has unique chemical properties. The structure is established, and it has a specific reaction path and activity in the chemical reaction, or due to the dislocation of each group, electronic effects, etc.
What are the main uses of 3-chloro-4-methoxybenzenemethanamine?
3-Chloro-4-methoxyaniline has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate. If you want to create a specific type of drug, it can be used as a starting material to gradually build a complex drug molecular structure through many chemical reactions. Due to its unique chemical structure, it can be cleverly combined with other compounds, thereby giving the drug a specific biological activity or helping it achieve therapeutic effects on specific diseases.
In the field of organic synthesis, 3-chloro-4-methoxyaniline also plays an important role. It can participate in a variety of reactions, such as nucleophilic substitution reactions, in which its methylamino group or chlorine atom can act as an active check point and interact with other nucleophilic reagents to form a series of new organic compounds. These new compounds may have unique physical and chemical properties and have potential uses in materials science and other fields.
Furthermore, this substance is also indispensable in the preparation of some fine chemicals. For example, the preparation of special dyes, fragrances, etc., 3-chloro-4-methoxyaniline can introduce specific functional groups into the product by virtue of its own structural characteristics, improve the color, odor and other properties of the product, and enhance the quality and added value of the product.
In the field of organic synthesis, 3-chloro-4-methoxyaniline also plays an important role. It can participate in a variety of reactions, such as nucleophilic substitution reactions, in which its methylamino group or chlorine atom can act as an active check point and interact with other nucleophilic reagents to form a series of new organic compounds. These new compounds may have unique physical and chemical properties and have potential uses in materials science and other fields.
Furthermore, this substance is also indispensable in the preparation of some fine chemicals. For example, the preparation of special dyes, fragrances, etc., 3-chloro-4-methoxyaniline can introduce specific functional groups into the product by virtue of its own structural characteristics, improve the color, odor and other properties of the product, and enhance the quality and added value of the product.
What are the physical properties of 3-chloro-4-methoxybenzenemethanamine?
3-Chloro-4-methoxyaniline is one of the organic compounds. Its physical properties are quite impressive, and let me tell them one by one.
First of all, under normal temperature and pressure, this substance is mostly colorless to light yellow liquid. Looking at its color, it is like the shimmer of early morning, elegant and clear, which makes people want to explore its inherent characteristics.
When it comes to the boiling point, the boiling point of 3-chloro-4-methoxyaniline is about a specific range. This boiling point value is like a beacon in the field of organic chemistry, guiding chemists to control the transformation of their physical states under different temperature environments. When the temperature approaches this boiling point, the substance gradually converts from liquid to gaseous state, completing a wonderful physical change.
Melting point is also one of its important physical properties. Although its melting point is not a well-known universal value, in fine chemical experiments and industrial production, this melting point parameter is crucial. Only by accurately grasping its melting point can we achieve precise control in the purification, crystallization and other links of the substance to ensure the purity and quality of the product.
Furthermore, solubility is also a property that cannot be ignored. 3-Chloro-4-methoxyaniline exhibits unique solubility in organic solvents. Common organic solvents, such as ethanol, ether, etc., can be fused with it, just like water and emulsion, forming a uniform mixed system. This solubility property provides a suitable medium for the reaction to proceed during the process of organic synthesis, which helps the reactants to fully contact and collide, and then promotes the smooth occurrence of chemical reactions.
In addition, density is also a key indicator to characterize its physical properties. The density of 3-chloro-4-methoxyaniline makes it occupy a specific spatial position in the liquid system, and it follows specific physical laws when interacting with other substances. This density parameter is not only related to its own physical behavior, but also plays a pivotal role in the separation and purification of mixtures.
To sum up, the physical properties of 3-chloro-4-methoxyaniline, from properties, boiling point, melting point, solubility to density, are like pieces of a puzzle, together to piece together its complete physical characteristics picture, laying a solid foundation for the research and application of organic chemistry.
First of all, under normal temperature and pressure, this substance is mostly colorless to light yellow liquid. Looking at its color, it is like the shimmer of early morning, elegant and clear, which makes people want to explore its inherent characteristics.
When it comes to the boiling point, the boiling point of 3-chloro-4-methoxyaniline is about a specific range. This boiling point value is like a beacon in the field of organic chemistry, guiding chemists to control the transformation of their physical states under different temperature environments. When the temperature approaches this boiling point, the substance gradually converts from liquid to gaseous state, completing a wonderful physical change.
Melting point is also one of its important physical properties. Although its melting point is not a well-known universal value, in fine chemical experiments and industrial production, this melting point parameter is crucial. Only by accurately grasping its melting point can we achieve precise control in the purification, crystallization and other links of the substance to ensure the purity and quality of the product.
Furthermore, solubility is also a property that cannot be ignored. 3-Chloro-4-methoxyaniline exhibits unique solubility in organic solvents. Common organic solvents, such as ethanol, ether, etc., can be fused with it, just like water and emulsion, forming a uniform mixed system. This solubility property provides a suitable medium for the reaction to proceed during the process of organic synthesis, which helps the reactants to fully contact and collide, and then promotes the smooth occurrence of chemical reactions.
In addition, density is also a key indicator to characterize its physical properties. The density of 3-chloro-4-methoxyaniline makes it occupy a specific spatial position in the liquid system, and it follows specific physical laws when interacting with other substances. This density parameter is not only related to its own physical behavior, but also plays a pivotal role in the separation and purification of mixtures.
To sum up, the physical properties of 3-chloro-4-methoxyaniline, from properties, boiling point, melting point, solubility to density, are like pieces of a puzzle, together to piece together its complete physical characteristics picture, laying a solid foundation for the research and application of organic chemistry.
What are 3-chloro-4-methoxybenzenemethanamine synthesis methods?
To prepare 3-chloro-4-methoxybenzoyl amine, the following numbers can be used.
First, 3-chloro-4-methoxybenzoic acid is used as the starting material. First, it is heated with thionyl chloride, and the carboxyl group of benzoic acid will be converted to an acid chloride to obtain 3-chloro-4-methoxybenzoyl chloride. This step requires an anhydrous environment to avoid hydrolysis of acid chloride. Then, 3-chloro-4-methoxybenzoyl chloride is reacted with excess ammonia, and the acid chloride group will be changed into an amide group to obtain 3-chloro-4-methoxybenzamide. Finally, using lithium aluminum hydride as a reducing agent, in anhydrous ethyl ether and other solvents, the reduction of 3-chloro-4-methoxybenzamide, the amide group is converted into a methylamino group, and the final product is 3-chloro-4-methoxyaniline.
Second, 3-chloro-4-methoxybenzaldehyde is used as the starting material. First, it is reacted with hydroxylamine hydrochloride in a weakly alkaline environment, and the aldehyde group is condensed with the hydroxylamine to form 3-chloro-4-methoxybenzaldehyde oxime. Then, metal zinc and hydrochloric acid are used as reducing agents to reduce 3-chloro-4-methoxybenzaldehyde oxime, and the oxime group is reduced to methylamine to obtain the target product 3-chloro-4-methoxyaniline.
Third, 3-chloro-4-methoxybenzyl bromide is used as the raw material. First, 3-chloro-4-methoxybenzyl bromide is reacted with potassium salt of phthalimide, and the bromine atom is replaced by a phthalimide group to obtain N - (3-chloro-4-methoxybenzyl) phthalimide. Subsequently, N - (3-chloro-4-methoxybenzyl) phthalimide is treated with hydrazine hydrate, and hydrazolysis occurs. The phthalimide group is converted to a methylamino group to obtain 3-chloro-4-methoxyaniline.
The above methods have advantages and disadvantages. In actual operation, it is necessary to weigh and choose the best method according to factors such as the availability of raw materials, the difficulty of reaction conditions, and the purity of the product.
First, 3-chloro-4-methoxybenzoic acid is used as the starting material. First, it is heated with thionyl chloride, and the carboxyl group of benzoic acid will be converted to an acid chloride to obtain 3-chloro-4-methoxybenzoyl chloride. This step requires an anhydrous environment to avoid hydrolysis of acid chloride. Then, 3-chloro-4-methoxybenzoyl chloride is reacted with excess ammonia, and the acid chloride group will be changed into an amide group to obtain 3-chloro-4-methoxybenzamide. Finally, using lithium aluminum hydride as a reducing agent, in anhydrous ethyl ether and other solvents, the reduction of 3-chloro-4-methoxybenzamide, the amide group is converted into a methylamino group, and the final product is 3-chloro-4-methoxyaniline.
Second, 3-chloro-4-methoxybenzaldehyde is used as the starting material. First, it is reacted with hydroxylamine hydrochloride in a weakly alkaline environment, and the aldehyde group is condensed with the hydroxylamine to form 3-chloro-4-methoxybenzaldehyde oxime. Then, metal zinc and hydrochloric acid are used as reducing agents to reduce 3-chloro-4-methoxybenzaldehyde oxime, and the oxime group is reduced to methylamine to obtain the target product 3-chloro-4-methoxyaniline.
Third, 3-chloro-4-methoxybenzyl bromide is used as the raw material. First, 3-chloro-4-methoxybenzyl bromide is reacted with potassium salt of phthalimide, and the bromine atom is replaced by a phthalimide group to obtain N - (3-chloro-4-methoxybenzyl) phthalimide. Subsequently, N - (3-chloro-4-methoxybenzyl) phthalimide is treated with hydrazine hydrate, and hydrazolysis occurs. The phthalimide group is converted to a methylamino group to obtain 3-chloro-4-methoxyaniline.
The above methods have advantages and disadvantages. In actual operation, it is necessary to weigh and choose the best method according to factors such as the availability of raw materials, the difficulty of reaction conditions, and the purity of the product.
What are the precautions in storage and transportation of 3-chloro-4-methoxybenzenemethanamine?
3-Chloro-4-methoxyaniline is an organic compound. When storing and transporting, many things need to be paid attention to.
Bear the brunt, and the storage environment is crucial. This compound should be placed in a cool, dry and well-ventilated place. Because of its certain chemical activity, high temperature or humid environment is prone to deterioration or chemical reactions. If heated, it may accelerate decomposition and even produce harmful gases; in case of moisture, reactions such as hydrolysis may occur, which will affect its quality.
Furthermore, keep away from ignition sources and oxidants. 3-Chloro-4-methoxyaniline may be flammable, and there is a risk of fire and explosion near the source of fire; and the contact of oxidizing agents with it can easily cause severe oxidation reactions and endanger safety.
Packaging should also not be ignored. Be sure to use well-sealed packaging materials to prevent leakage. Leakage will not only cause material loss, but also its volatile gases may be harmful to the environment and human health. Packaging materials should be able to withstand the chemical properties of this compound and not react with it.
When transporting, strictly abide by relevant regulations and operating procedures. Vehicles should be equipped with corresponding fire and leakage emergency treatment equipment, just in case. And avoid bumps and vibrations during transportation to avoid leakage caused by damaged packaging.
In addition, operators must be professionally trained to be familiar with the characteristics of this compound and emergency treatment methods. In the event of a leak or other accident, they can respond quickly and correctly to reduce the harm. In short, careful storage and transportation can ensure the safety of 3-chloro-4-methoxyaniline.
Bear the brunt, and the storage environment is crucial. This compound should be placed in a cool, dry and well-ventilated place. Because of its certain chemical activity, high temperature or humid environment is prone to deterioration or chemical reactions. If heated, it may accelerate decomposition and even produce harmful gases; in case of moisture, reactions such as hydrolysis may occur, which will affect its quality.
Furthermore, keep away from ignition sources and oxidants. 3-Chloro-4-methoxyaniline may be flammable, and there is a risk of fire and explosion near the source of fire; and the contact of oxidizing agents with it can easily cause severe oxidation reactions and endanger safety.
Packaging should also not be ignored. Be sure to use well-sealed packaging materials to prevent leakage. Leakage will not only cause material loss, but also its volatile gases may be harmful to the environment and human health. Packaging materials should be able to withstand the chemical properties of this compound and not react with it.
When transporting, strictly abide by relevant regulations and operating procedures. Vehicles should be equipped with corresponding fire and leakage emergency treatment equipment, just in case. And avoid bumps and vibrations during transportation to avoid leakage caused by damaged packaging.
In addition, operators must be professionally trained to be familiar with the characteristics of this compound and emergency treatment methods. In the event of a leak or other accident, they can respond quickly and correctly to reduce the harm. In short, careful storage and transportation can ensure the safety of 3-chloro-4-methoxyaniline.
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