3-Chloro-4-Methylbenzenesulfonyl Chloride

Linshang Chemical

Specifications

HS Code

320534

Name 3-Chloro-4-Methylbenzenesulfonyl Chloride
Chemical Formula C7H6Cl2O2S
Molar Mass 225.09 g/mol
Appearance Colorless to pale yellow liquid
Boiling Point Around 274 - 276 °C
Density Approx. 1.47 g/cm³
Solubility Soluble in organic solvents like dichloromethane, insoluble in water
Pungency Has a pungent odor
Reactivity Reactive towards nucleophiles due to the presence of sulfonyl chloride group

As an accredited 3-Chloro-4-Methylbenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 3 - chloro - 4 - methylbenzenesulfonyl chloride packaged in a sealed glass bottle.
Storage 3 - Chloro - 4 - methylbenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and moisture. It should be kept in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from incompatible substances like bases, oxidizing agents, and water - reactive compounds to prevent dangerous reactions.
Shipping 3 - Chloro - 4 - methylbenzenesulfonyl chloride is a hazardous chemical. It should be shipped in accordance with strict regulations, using well - sealed, corrosion - resistant containers, marked clearly with relevant hazard labels, and transported by approved carriers.
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3-Chloro-4-Methylbenzenesulfonyl Chloride 3-Chloro-4-Methylbenzenesulfonyl Chloride
General Information
Where to Buy 3-Chloro-4-Methylbenzenesulfonyl Chloride in China?
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Frequently Asked Questions

As a leading 3-Chloro-4-Methylbenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-chloro-4-methylbenzenesulfonyl Chloride?
3-Chloro-4-methylbenzenesulfonyl chloride has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate.
In the preparation of various sulfonamide compounds, 3-chloro-4-methylbenzenesulfonyl chloride can react with amines, and by virtue of this reaction, a diverse sulfonamide structure can be constructed. This structure is of great significance in medicinal chemistry. Many pharmacologically active drug molecules contain sulfonamide fragments, which can help to develop new drugs.
In the field of materials science, this compound also has extraordinary performance. For example, when preparing some functional polymer materials, it can be introduced into the polymer chain to give the material good solubility, thermal stability and special electrical properties. Due to the characteristics of benzene ring and sulfonyl chloride group, it can be polymerized with other monomers, so as to prepare polymer with specific properties, which can be used in electronic devices, optical materials and many other aspects.
In addition, in the field of dye synthesis, 3-chloro-4-methylbenzenesulfonyl chloride also plays an important role. Dyes with special colors and properties can be synthesized by reacting with specific compounds containing nitrogen and hydroxyl groups to meet the needs of different industries for dye color and fastness.
In summary, 3-chloro-4-methylbenzenesulfonyl chloride is an indispensable and important chemical raw material in many fields such as organic synthesis, materials science, and dye synthesis, and plays a crucial role in promoting the development of related fields.
What are the physical properties of 3-chloro-4-methylbenzenesulfonyl Chloride?
3-Chloro-4-methylbenzenesulfonyl chloride is an important compound in organic chemistry. Its physical properties are unique and related to many properties of this substance, which is crucial for applications in chemical and related fields.
First of all, its appearance, 3-chloro-4-methylbenzenesulfonyl chloride is usually colorless to slightly yellow liquid, and it looks like a clear oil with uniform texture and no obvious impurities. This appearance feature can help chemical practitioners to initially identify, and visually judge whether its state is normal during production, storage and use.
The boiling point is about a specific numerical range. The boiling point is the temperature at which a substance changes from a liquid state to a gas state. For 3-chloro-4-methylbenzenesulfonyl chloride, it is crucial to know the boiling point accurately. In chemical operations such as distillation and separation, the boiling point can be effectively separated from other substances to obtain high-purity products. And whether the boiling point is stable or not also reflects the purity of the substance. If the boiling point deviates from the normal range, it may suggest that it contains impurities.
Furthermore, the melting point is also one of its important physical properties. Although it is liquid at room temperature, knowing the melting point can understand its state change at low temperature. When the temperature drops to near the melting point, 3-chloro-4-methylbenzenesulfonyl chloride will gradually change from liquid to solid. This property needs to be taken into account during storage and transportation to ensure that the ambient temperature is suitable to prevent changes in the state of the substance from affecting its quality.
In addition, density is also a physical property that cannot be ignored. 3-Chloro-4-methylbenzenesulfonyl chloride has a specific density value, which determines its positional relationship when mixed with other liquids. In a chemical reaction or preparation process, if it involves mixing with other liquids, the density difference can affect the uniformity of mixing and the reaction process. For example, when the denser 3-chloro-4-methylbenzenesulfonyl chloride is mixed with a less dense liquid, it may initially sink, and it is necessary to promote uniform mixing by means of stirring.
In terms of solubility, 3-chloro-4-methylbenzenesulfonyl chloride exhibits a certain solubility in organic solvents, but is insoluble in water. This characteristic determines the difference in the choice of reaction system and product separation method. In organic synthesis reactions, suitable organic solvents are often selected as reaction media according to their solubility to facilitate the smooth progress of the reaction. In the process of product separation and purification, its insolubility in water can be used to remove impurities and improve the purity of the product by means of aqueous-organic phase separation. In conclusion, the physical properties of 3-chloro-4-methylbenzenesulfonyl chloride, from its appearance to its boiling point, melting point, density, and solubility, all have an important impact on its production, storage, transportation, and application in the chemical industry. Chemical practitioners must be familiar with and make good use of it in order to ensure safe and efficient operation and achieve high-quality product output.
3-chloro-4-methylbenzenesulfonyl Chloride chemically stable?
3-Chloro-4-methylbenzenesulfonyl chloride, the chemical properties of this substance are not stable. It is active, and the chemical activity of the sulfonyl chloride group (-SO 2O Cl) is quite high.
Looking at the reaction, when exposed to water, it is very easy to hydrolyze. The sulfonyl chloride group will interact with water and gradually transform into a sulfonic acid group (-SO 🥰 H), and release hydrogen chloride gas at the same time. This reaction is rapid and hydrogen chloride is irritating. During operation, all attention should be paid to prevent it from escaping and causing damage.
And because the chlorine atom is on the benzene ring, the electron cloud density around the benzene ring is affected by it, so that the molecule exhibits specific reactivity in the process of nucleophilic substitution reaction. Although the chlorine atom on the aromatic ring has slightly different reactivity than the benzene ring, it can also participate in many reactions under specific conditions.
Furthermore, the methyl group attached to the benzene ring also has an effect on the electron cloud distribution of the benzene ring, and interacts with the sulfonyl chloride group, resulting in more complex and variable chemical properties of the molecule as a whole. Due to its active characteristics, when storing, it is necessary to choose a dry, cool and heat-proof place to isolate water vapor to prevent its deterioration. During operation, strict procedures must also be followed to ensure safety and prevent accidents due to its chemical activity.
What are the application steps of 3-chloro-4-methylbenzenesulfonyl Chloride in synthesis?
In the synthesis of 3-chloro-4-methylbenzenesulfonyl chloride, the application steps are quite critical. First of all, the preparation of raw materials needs to be carefully selected to ensure its high quality. When synthesizing this compound, the raw materials used should be pure and flawless to make the reaction smooth.
Second, the control of the reaction conditions is crucial. The temperature, the reaction time, and the adjustment of pH are all related to the success or failure of the reaction. Generally speaking, if the temperature is suitable or in a certain range, if the temperature is too high, it may cause side reactions; if the temperature is too low, the reaction will be slow or even stagnant. The reaction time also needs to be accurately grasped. If it is too short, the reaction will not be completed. If it is too long, it will consume resources and may cause the product to deteriorate. The adjustment of pH can be achieved by means of buffer solutions to create an environment conducive to the reaction.
Furthermore, the monitoring of the reaction process is indispensable. With spectroscopic analysis, chromatographic analysis and other technologies, real-time insight into the reaction process can be used to know the consumption of raw materials and the formation of products. Once an abnormality is detected, the reaction conditions can be adjusted in time to ensure that the reaction proceeds as expected.
After synthesizing the product, the separation and purification steps cannot be ignored. By recrystallization, distillation, extraction and other methods, impurities are removed and product purity is improved. During recrystallization, the choice of solvent is crucial. The selected solvent can dissolve the product and impurities at high temperature, and only crystallize the product at low temperature. Distillation is based on the difference in the boiling point of each substance to achieve separation. Extraction also relies on the different solubility of the substance in different solvents to achieve the purpose of purification. In this way, high-purity 3-chloro-4-methylbenzenesulfonyl chloride can be obtained for subsequent synthesis.
What are the storage conditions for 3-chloro-4-methylbenzenesulfonyl Chloride?
3-Chloro-4-methylbenzenesulfonyl chloride, this is a chemical substance. The rules of its storage are extremely important and related to safety and quality.
Because of its chemical activity, it is very easy to react in contact with water, so it should be placed in a dry place. It is necessary to avoid water vapor. If the moisture in the warehouse is heavy, the water vapor will come into contact with 3-chloro-4-methylbenzenesulfonyl chloride, which may cause hydrolysis, resulting in damage to its quality or unsafe conditions.
And it is quite sensitive to temperature and should be stored in a cool place. Under high temperatures, this compound may be more active, which may accelerate the reaction, cause decomposition, and even cause danger. Therefore, the temperature should be controlled within a specific range to ensure its chemical stability.
In addition, 3-chloro-4-methylbenzenesulfonyl chloride is corrosive, and the storage container must be resistant to corrosion. Glass materials or specific plastics must be able to resist corrosion to prevent damage to the container and leakage, endangering the environment and personal safety.
The storage place should be well ventilated. If the space is closed, its volatile gas accumulates and the concentration is too high, which will not only damage the air, but also be harmful to health if inhaled, and the gas accumulates or there is a risk of fire and explosion.
At the same time, this compound must be isolated from oxidizing agents, alkalis, etc. Due to the encounter of 3-chloro-4-methylbenzenesulfonyl chloride with oxidants, or a violent oxidation reaction; and the interaction with bases, it can also cause uncontrollable chemical changes, which can cause safety accidents.
In summary, 3-chloro-4-methylbenzenesulfonyl chloride should be stored in a dry, cool and well-ventilated place, in a corrosion-resistant container, and isolated from incompatible materials, so as to ensure the safety of storage and ensure its quality.