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3-Chloro-5-Iodo-1-Bromobenzene
Linshang Chemical
|
HS Code |
799132 |
| Chemical Formula | C6H3BrClI |
| Molar Mass | 329.35 g/mol |
| Appearance | Solid (likely off - white or colored depending on purity) |
| Physical State At Room Temperature | Solid |
| Boiling Point | High (due to heavy halogens, exact value needs experimental determination) |
| Melting Point | Needs experimental determination |
| Density | Needs experimental determination |
| Solubility In Water | Low (non - polar molecule due to halogen substitution) |
| Solubility In Organic Solvents | Soluble in non - polar or slightly polar organic solvents like benzene, toluene |
| Polarity | Polar due to electronegativity differences of halogens |
| Reactivity | Reactive towards nucleophilic substitution reactions due to halogen atoms |
As an accredited 3-Chloro-5-Iodo-1-Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 3 - chloro - 5 - iodo - 1 - bromobenzene packaged in a sealed glass bottle. |
| Storage | 3 - Chloro - 5 - iodo - 1 - bromobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant material. This aromatic halide compound is sensitive to environmental factors, and proper storage helps maintain its stability and prevent potential hazards. |
| Shipping | 3 - Chloro - 5 - iodo - 1 - bromobenzene is shipped in tightly - sealed, corrosion - resistant containers. It's handled with care to prevent spills, following strict hazardous chemical shipping regulations to ensure safety during transit. |
Competitive 3-Chloro-5-Iodo-1-Bromobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3-Chloro-5-Iodo-1-Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the Chinese name of 3-chloro-5-iodo-1-bromobenzene?
3-Chloro-5-iodine-1-bromobenzene is one of the organic compounds. According to its naming, the benzene ring is the base, and the atoms on the ring are named according to the position and type. "1-bromine" is said to have a bromine atom connected at 1 position of the benzene ring; "3-chlorine" is the chlorine atom at the 3rd position of the benzene ring; "5-iodine" is the iodine atom at the 5th position of the benzene ring. Such naming is in line with the naming rules of organic chemistry, which can show the position of each atom in its molecular structure, so that scholars can see the known structure and greatly help in the research and synthesis of organic compounds. The naming of this compound follows the system nomenclature to accurately describe its chemical structure, making it an indispensable symbol in the field of chemistry.
What are the physical properties of 3-chloro-5-iodo-1-bromobenzene?
3-Chloro-5-iodine-1-bromobenzene is an organic halogenated aromatic hydrocarbon. Its physical properties are particularly important, and it is relevant to its application in many fields.
Let's talk about the appearance first. At room temperature, this substance is either a colorless to light yellow liquid or a crystalline solid. It has a pure texture and no obvious impurities. The reason for its color is the interaction between the halogen atom and the benzene ring in the molecular structure, resulting in specific absorption and reflection of light.
In terms of boiling point, due to the existence of van der Waals force between molecules, and the presence of halogen atoms enhances the polarity of molecules, and the intermolecular force increases, so the boiling point is quite high. At about [X] ° C, such a high boiling point allows it to maintain a relatively stable state in ordinary environments.
The melting point is also affected by halogen atoms, the molecular arrangement is more regular and tight, the lattice energy is increased, and the melting point can reach [X] ° C. This property is of great significance in the separation, purification and solid-state storage of substances.
In terms of solubility, because the benzene ring is a non-polar structure, while the halogen atom has a certain polarity, the whole is weakly polar. Therefore, it has good solubility in non-polar or weakly polar organic solvents such as ether and carbon tetrachloride; in water with strong polarity, the solubility is very small. The density of
is higher than that of water, and the molecular weight increases due to the larger relative atomic weight of halogen atoms. Under the same volume, the mass is larger, and the density is about [X] g/cm ³. This density characteristic can be used as an important basis when it comes to operations such as liquid-liquid separation.
The physical properties of 3-chloro-5-iodine-1-bromobenzene have laid a solid foundation for its application in organic synthesis, materials science and other fields.
Let's talk about the appearance first. At room temperature, this substance is either a colorless to light yellow liquid or a crystalline solid. It has a pure texture and no obvious impurities. The reason for its color is the interaction between the halogen atom and the benzene ring in the molecular structure, resulting in specific absorption and reflection of light.
In terms of boiling point, due to the existence of van der Waals force between molecules, and the presence of halogen atoms enhances the polarity of molecules, and the intermolecular force increases, so the boiling point is quite high. At about [X] ° C, such a high boiling point allows it to maintain a relatively stable state in ordinary environments.
The melting point is also affected by halogen atoms, the molecular arrangement is more regular and tight, the lattice energy is increased, and the melting point can reach [X] ° C. This property is of great significance in the separation, purification and solid-state storage of substances.
In terms of solubility, because the benzene ring is a non-polar structure, while the halogen atom has a certain polarity, the whole is weakly polar. Therefore, it has good solubility in non-polar or weakly polar organic solvents such as ether and carbon tetrachloride; in water with strong polarity, the solubility is very small. The density of
is higher than that of water, and the molecular weight increases due to the larger relative atomic weight of halogen atoms. Under the same volume, the mass is larger, and the density is about [X] g/cm ³. This density characteristic can be used as an important basis when it comes to operations such as liquid-liquid separation.
The physical properties of 3-chloro-5-iodine-1-bromobenzene have laid a solid foundation for its application in organic synthesis, materials science and other fields.
What are the main uses of 3-chloro-5-iodo-1-bromobenzene?
3-Chloro-5-iodine-1-bromobenzene, an organic compound, has important uses in many fields.
First, in the field of organic synthesis, it plays the role of a key intermediate. Organic synthesis aims to construct various complex organic molecules, and the chlorine, iodine, and bromine atoms in this compound are all active check points. It can interact with different nucleophiles through many chemical reactions, such as nucleophilic substitution reactions, and then introduce specific functional groups, laying the foundation for the synthesis of organic compounds with diverse structures. Taking nucleophilic substitution reaction as an example, hydroxyl negative ions as nucleophiles can replace chlorine atoms to form new compounds containing hydroxyl groups, which greatly expands the pathways and possibilities of organic synthesis.
Second, it also occupies an important position in the field of medicinal chemistry. Drug development requires the design and synthesis of molecules with specific biological activities. The unique structure of 3-chloro-5-iodine-1-bromobenzene can become a key fragment of drug molecules. Through further chemical modification, the physicochemical properties and biological activities of drug molecules can be adjusted, such as improving the solubility, permeability, and affinity with specific biological targets of drugs, providing important starting materials for the development of new drugs.
Third, in the field of materials science, its use is also quite extensive. With the increase in demand for new functional materials, 3-chloro-5-iodine-1-bromobenzene can be used as a basic unit for building functional materials. For example, polymer materials with special optical and electrical properties can be prepared by polymerization with other monomers, which shows potential application value in optoelectronic devices, sensors and other fields.
3-chloro-5-iodine-1-bromobenzene plays an indispensable role in many fields such as organic synthesis, pharmaceutical chemistry, and materials science, and promotes the continuous development and progress of various fields.
First, in the field of organic synthesis, it plays the role of a key intermediate. Organic synthesis aims to construct various complex organic molecules, and the chlorine, iodine, and bromine atoms in this compound are all active check points. It can interact with different nucleophiles through many chemical reactions, such as nucleophilic substitution reactions, and then introduce specific functional groups, laying the foundation for the synthesis of organic compounds with diverse structures. Taking nucleophilic substitution reaction as an example, hydroxyl negative ions as nucleophiles can replace chlorine atoms to form new compounds containing hydroxyl groups, which greatly expands the pathways and possibilities of organic synthesis.
Second, it also occupies an important position in the field of medicinal chemistry. Drug development requires the design and synthesis of molecules with specific biological activities. The unique structure of 3-chloro-5-iodine-1-bromobenzene can become a key fragment of drug molecules. Through further chemical modification, the physicochemical properties and biological activities of drug molecules can be adjusted, such as improving the solubility, permeability, and affinity with specific biological targets of drugs, providing important starting materials for the development of new drugs.
Third, in the field of materials science, its use is also quite extensive. With the increase in demand for new functional materials, 3-chloro-5-iodine-1-bromobenzene can be used as a basic unit for building functional materials. For example, polymer materials with special optical and electrical properties can be prepared by polymerization with other monomers, which shows potential application value in optoelectronic devices, sensors and other fields.
3-chloro-5-iodine-1-bromobenzene plays an indispensable role in many fields such as organic synthesis, pharmaceutical chemistry, and materials science, and promotes the continuous development and progress of various fields.
What are 3-chloro-5-iodo-1-bromobenzene synthesis methods?
To prepare 3-chloro-5-iodine-1-bromobenzene, it can be obtained from benzene and converted in multiple steps.
First, benzene and bromine, plus iron bromide as catalyst, undergo electrophilic substitution to obtain bromobenzene. Because bromine is an ortho-para locator, the subsequent reaction can introduce his group into its ortho-position and para-position.
Second, bromobenzene and chlorine, catalyzed by ferric chloride, can obtain p-bromochlorobenzene. The electrophilic substitution activity of capping chlorine is higher than that of bromine, and the ortho-localization effect of bromine makes chlorine easy to be substituted by bromine.
Furthermore, p-bromochlorobenzene and iodine, under specific conditions, if an appropriate catalyst is added and the reaction environment is mild, iodine can replace the ortho-hydrogen of bromine on the benzene ring to obtain 3-chloro-5-iodine-1-bromobenzene. In this step, it is necessary to pay attention to the low activity of iodine, and the reaction conditions need to be precisely regulated.
Or the benzene chloride can be substituted first to obtain chlorobenzene, chlorobenzene bromide to obtain isobromochlorobenzene, and isobromochlorobenzene can then react with iodine. Under suitable conditions, iodine can replace the ortho-hydrogen of chlorine on isobromochlorobenzene, and the target product can also be obtained. However, the reaction selectivity and condition control In conclusion, the reaction conditions, the proportion of reactants and the choice of catalyst are all crucial for the synthesis of 3-chloro-5-iodine-1-bromobenzene.
First, benzene and bromine, plus iron bromide as catalyst, undergo electrophilic substitution to obtain bromobenzene. Because bromine is an ortho-para locator, the subsequent reaction can introduce his group into its ortho-position and para-position.
Second, bromobenzene and chlorine, catalyzed by ferric chloride, can obtain p-bromochlorobenzene. The electrophilic substitution activity of capping chlorine is higher than that of bromine, and the ortho-localization effect of bromine makes chlorine easy to be substituted by bromine.
Furthermore, p-bromochlorobenzene and iodine, under specific conditions, if an appropriate catalyst is added and the reaction environment is mild, iodine can replace the ortho-hydrogen of bromine on the benzene ring to obtain 3-chloro-5-iodine-1-bromobenzene. In this step, it is necessary to pay attention to the low activity of iodine, and the reaction conditions need to be precisely regulated.
Or the benzene chloride can be substituted first to obtain chlorobenzene, chlorobenzene bromide to obtain isobromochlorobenzene, and isobromochlorobenzene can then react with iodine. Under suitable conditions, iodine can replace the ortho-hydrogen of chlorine on isobromochlorobenzene, and the target product can also be obtained. However, the reaction selectivity and condition control In conclusion, the reaction conditions, the proportion of reactants and the choice of catalyst are all crucial for the synthesis of 3-chloro-5-iodine-1-bromobenzene.
3-chloro-5-iodo-1-bromobenzene what are the precautions during storage and transportation?
3-Chloro-5-iodine-1-bromobenzene is an organic compound. When storing and transporting, many matters need to be paid attention to.
First words storage. This compound has a certain chemical activity and needs to be stored in a cool, dry and well-ventilated place. Because it is sensitive to light and heat, it should be avoided from direct light and high temperature environment to prevent decomposition and deterioration. It needs to be stored in a sealed container to prevent oxidation or water vapor absorption due to contact with air. If stored in an improper environment, or its chemical properties are changed, it will affect subsequent use.
Next talk about transportation. Make sure that the packaging is intact during transportation to prevent leakage. Due to its toxicity and corrosiveness, leakage may endanger the safety of transportation personnel and the environment. It is advisable to maintain a stable temperature and humidity during transportation to avoid severe vibration and collision. If the package is damaged and leaks, it should be dealt with immediately in accordance with relevant safety procedures, evacuate the crowd, clean it up by professional means, and prevent the spread of harmful substances.
Furthermore, the personnel who operate this compound should be professionally trained and familiar with its properties and safe operation specifications. Storage and transportation sites should be equipped with emergency treatment equipment and protective equipment, such as fire extinguishers, adsorption materials, protective clothing, gloves and gas masks. In case of an accident, it can be responded to in time to minimize the harm.
In short, the storage and transportation of 3-chloro-5-iodine-1-bromobenzene must adhere to strict safety regulations, operate with caution, and take comprehensive protection, so as to ensure the safety of personnel and the environment, and maintain the normal order of production and use.
First words storage. This compound has a certain chemical activity and needs to be stored in a cool, dry and well-ventilated place. Because it is sensitive to light and heat, it should be avoided from direct light and high temperature environment to prevent decomposition and deterioration. It needs to be stored in a sealed container to prevent oxidation or water vapor absorption due to contact with air. If stored in an improper environment, or its chemical properties are changed, it will affect subsequent use.
Next talk about transportation. Make sure that the packaging is intact during transportation to prevent leakage. Due to its toxicity and corrosiveness, leakage may endanger the safety of transportation personnel and the environment. It is advisable to maintain a stable temperature and humidity during transportation to avoid severe vibration and collision. If the package is damaged and leaks, it should be dealt with immediately in accordance with relevant safety procedures, evacuate the crowd, clean it up by professional means, and prevent the spread of harmful substances.
Furthermore, the personnel who operate this compound should be professionally trained and familiar with its properties and safe operation specifications. Storage and transportation sites should be equipped with emergency treatment equipment and protective equipment, such as fire extinguishers, adsorption materials, protective clothing, gloves and gas masks. In case of an accident, it can be responded to in time to minimize the harm.
In short, the storage and transportation of 3-chloro-5-iodine-1-bromobenzene must adhere to strict safety regulations, operate with caution, and take comprehensive protection, so as to ensure the safety of personnel and the environment, and maintain the normal order of production and use.
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