3-Chlorobenzeneamine
Linshang Chemical
HS Code |
130329 |
Name | 3 - Chlorobenzeneamine |
Molecular Formula | C6H6ClN |
Molar Mass | 127.57 g/mol |
Appearance | Pale yellow to brown liquid or solid |
Odor | Aminic odor |
Density | 1.21 g/cm³ (at 20°C) |
Boiling Point | 230 - 232°C |
Melting Point | 1 - 3°C |
Solubility In Water | Slightly soluble |
Flash Point | 106°C |
Pka | 4.17 |
Refractive Index | 1.598 - 1.600 (at 20°C) |
As an accredited 3-Chlorobenzeneamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500 - gram bottle of 3 - chlorobenzeneamine, tightly sealed for chemical safety. |
Storage | 3 - Chlorobenzeneamine should be stored in a cool, dry, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly closed container to prevent vapor release. Store it separately from oxidizing agents, acids, and foodstuffs. Ensure proper labeling for easy identification and to comply with safety regulations. |
Shipping | 3 - Chlorobenzeneamine is shipped in accordance with strict chemical transport regulations. It's typically in sealed, corrosion - resistant containers, transported by specialized carriers to ensure safety during transit, avoiding exposure and potential hazards. |
Competitive 3-Chlorobenzeneamine prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 3-Chlorobenzeneamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
First, in the field of pharmaceutical synthesis, it plays a key role. It can be used as an intermediate for the preparation of a variety of drugs. For example, through specific chemical reactions, its structure is ingeniously modified to synthesize compounds with specific pharmacological activities, such as some antibacterial drugs, nervous system drugs, etc. This is because the thiophene ring structure of 3-bromothiophene and the characteristics of bromine atoms give it unique chemical activity and can react precisely with other molecules to construct complex structures that meet the needs of drug design.
Second, it is also indispensable in the field of materials science. In the preparation of organic optoelectronic materials, 3-bromothiophene is often used as a starting material. After a series of reactions, it can be introduced into the conjugated system to improve the photoelectric properties of the material. For example, when synthesizing organic Light Emitting Diode (OLED) materials, 3-bromothiophene can be polymerized to form a polymer with good luminescent properties and charge transport properties, thereby improving the luminous efficiency and stability of OLED devices.
Furthermore, 3-bromothiophene is also useful in the synthesis of pesticides. As a key intermediate in the synthesis of new pesticides, pesticide compounds with high insecticidal, bactericidal or herbicidal activities can be synthesized by rationally designing the reaction path. Due to the existence of thiophene rings, pesticides can be endowed with unique biological activity and environmental compatibility, which is conducive to the development of greener and more efficient pesticide products.
In summary, 3-bromothiophene plays a pivotal role in many fields such as medicine, materials, and pesticides due to its unique chemical structure and activity, providing an indispensable material basis for innovation and development in various fields.
Under normal conditions, it is in the shape of a black or light-colored liquid, and has a strong pungent taste. Smell, pungent and resistant, this taste is one of the important characteristics to distinguish. Its density is high in water, 1.49 g/cm ³, placed in water, and must sink to the bottom. This property can also be used for preliminary separation.
The melting temperature of 3-% bromic acid is low, at -66.5 ° C, so it is solid in cold environments. And its boiling phase is high, at 126 ° C. This characteristic of melting makes it more liquid in general environments.
In addition, 3-% bromic acid has good solubility, and can be miscible in water in any ratio to form a homogeneous solution. This property makes it easy to mix other water-soluble substances in the reaction of polymers and workmanship. Its aqueous solution is acidic, and it can be mixed with multiple gold, gold oxides, and biological reactions, exhibiting the universality of acid.
Its performance is also not to be ignored, although some bromic acid molecules are still mixed into the air to form a white acid. This acid has a strong stimulating effect on the eyes, respiratory tract and other organs. It must be carefully prevented during operation.
Therefore, understanding the physical rationality of 3-% bromic acid is of paramount importance in terms of its existence, use, etc., which can ensure human safety and the benefit of the chemical process.
First, the carbon-carbon double bond gives it the ability to add to the reaction. If it can be added to the bromine elemental substance, the double bond is opened, and the two bromine atoms are respectively connected to the carbon atoms at both ends of the original double bond to generate 1,2,3-tribromopropane. This reaction condition is mild and can be carried out smoothly in organic solvents such as carbon tetrachloride at room temperature. It can also be added with hydrogen under the action of catalysts such as nickel, and the double bond is hydrogenated to obtain 1-bromopropane.
Secondly, the presence of halogen and bromine atoms enables the substitution reaction of 3-bromopropene. Under alkaline conditions, such as co-heating with sodium hydroxide aqueous solution, bromine atoms can be replaced by hydroxyl groups to form 3-hydroxypropylene. If reacted with sodium alcohol, nucleophilic substitution will occur to form corresponding ether compounds.
In addition, 3-bromopropylene can also participate in the elimination reaction. Heating in potassium hydroxide alcohol solution, bromine atoms are removed from hydrogen atoms on adjacent carbon atoms to form propargyne, potassium bromide and water.
Because of its chemical activity of both carbon-carbon double bonds and halogen atoms, 3-bromopropylene acts as a key intermediate in many organic synthesis reactions and is widely used in drug synthesis, material preparation and many other fields.
First, thiophene is used as the base material, and it is prepared by bromination reaction. In the reactor, an appropriate amount of nathiophene is slowly injected into bromine. In this case, the reaction temperature needs to be carefully controlled, and it should be cooled in an ice-water bath to maintain it at a low temperature. Because the bromination reaction is quite violent, if the temperature is too high, it is easy to cause side reactions to cluster and lose the purity of the product. When the bromine is injected, it should be slow and uniform, and at the same time, it should be stirred at the speed of a mixer to make the materials fully mixed and the reaction is uniform.
During the reaction, hydrogen bromide gas can be observed to escape. This is a by-product, which needs to be captured by a suitable device to prevent it from escaping into the atmosphere, polluting the environment and harming the human body. After the reaction is completed, a mixture containing 3-bromothiophene is obtained, but it still contains unreacted raw materials, by-products and solvents.
Then proceed to separation and purification. First, wash with water to remove soluble impurities in the mixture, such as hydrogen bromide. Later, extract with organic solvents. The extraction agent is selected, and it has good solubility to 3-bromothiophene and is easy to stratify with water. Commonly used such as dichloromethane, ether, etc. After extraction, the organic phase is separated and dried with a desiccant such as anhydrous sodium sulfate to remove water from it.
Then by distillation, the boiling points of 3-bromothiophene and the rest of the components are separated. Control the distillation temperature and pressure to obtain a pure 3-bromothiophene fraction, which is the target product. The whole process requires rigorous operation at each step to ensure the quality and yield of the product.
First safety protection. This substance is irritating, or causes damage to the eyes, skin and respiratory tract. When taking it, be sure to wear suitable protective equipment, such as gloves, goggles and gas masks, to prevent contact and inhalation, to ensure personal safety.
Times and storage conditions. Store in a cool, well-ventilated place, away from fire, heat sources, and avoid direct sunlight. It should be stored separately from oxidants, acids, etc., and should not be mixed to prevent dangerous reactions.
The other is the operating specification. The operation must be carried out in the fume hood to ensure air circulation and reduce the concentration of harmful gases. The operation of the taking process should be precise and rapid to prevent its volatilization and leakage. If a leak occurs accidentally, the personnel should be evacuated to a safe area immediately, and the fire source should be cut off. Emergency personnel need to wear full masks, wear anti-virus clothing, and mix sand, dry lime or soda ash to collect the leakage, and then properly dispose of it.
When using 3-bromothiophene in chemical reactions, it is necessary to be familiar with its reactivity and selectivity. Due to its structural characteristics, it may exhibit different reaction behaviors under different reaction conditions. It is necessary to precisely adjust the reaction temperature, time and reactant ratio according to the reaction requirements to ensure the smooth progress of the reaction and obtain the expected product. At the same time, it is necessary to recognize and deal with the by-products during the reaction process.
In addition, after the experiment is completed, the remaining 3-bromothiophene and reaction waste should be properly disposed of in accordance with relevant regulations, and must not be discarded at will to avoid polluting the environment.

Scan to WhatsApp