Linshang Chemical
PRODUCTS
3-Chlorobenzenecarboximidamide Hydrochloride
Linshang Chemical
|
HS Code |
913991 |
| Chemical Formula | C7H7Cl2N3 |
| Molar Mass | 204.056 g/mol |
| Appearance | Solid |
| Solubility In Water | Soluble |
| Melting Point | 190 - 192 °C |
| Purity | Typically high purity for research use |
| Stability | Stable under normal conditions |
| Hazard Class | Irritant (may cause skin, eye and respiratory irritation) |
As an accredited 3-Chlorobenzenecarboximidamide Hydrochloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 3 - chlorobenzenecarboximidamide Hydrochloride packaged in a sealed plastic bag. |
| Storage | 3 - Chlorobenzenecarboximidamide Hydrochloride should be stored in a cool, dry place, away from direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and exposure to air. Store it separately from incompatible substances, such as strong oxidizing agents. Ensure the storage area has good ventilation to avoid the build - up of potentially harmful fumes. |
| Shipping | 3 - Chlorobenzenecarboximidamide Hydrochloride is shipped in sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations to ensure safety during transit, with proper labeling and handling precautions. |
Competitive 3-Chlorobenzenecarboximidamide Hydrochloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 3-Chlorobenzenecarboximidamide Hydrochloride in China?
As a trusted 3-Chlorobenzenecarboximidamide Hydrochloride manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3-Chlorobenzenecarboximidamide Hydrochloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
3-chlorobenzenecarboximidamide chemical structure of hydrochloride
3-chlorobenzenecarboximidamide Hydrochloride is 3-chlorobenzamidine hydrochloride, and its chemical structure is as follows:
The parent of this compound is a benzene ring, which is connected to a formamidine group (-C (= NH) NH -2) at the 3 position (interposition) of the benzene ring, and there is also a chlorine atom connected to the benzene ring, and the whole exists in the form of hydrochloride, which means that the nitrogen atom in the formamidine group binds a hydrogen ion (H 🥰) and forms a salt with the chloride ion (Cl). In its structure, the benzene ring gives the compound certain aromaticity and stability, while the formamidine group has certain alkalinity and nucleophilicity, which can participate in a variety of chemical reactions. The presence of chlorine atoms, due to its high electronegativity, will affect the electron cloud distribution of the benzene ring, which in turn affects the physical and chemical properties of the whole molecule. The hydrochloride form enhances the solubility of the compound in polar solvents.
The parent of this compound is a benzene ring, which is connected to a formamidine group (-C (= NH) NH -2) at the 3 position (interposition) of the benzene ring, and there is also a chlorine atom connected to the benzene ring, and the whole exists in the form of hydrochloride, which means that the nitrogen atom in the formamidine group binds a hydrogen ion (H 🥰) and forms a salt with the chloride ion (Cl). In its structure, the benzene ring gives the compound certain aromaticity and stability, while the formamidine group has certain alkalinity and nucleophilicity, which can participate in a variety of chemical reactions. The presence of chlorine atoms, due to its high electronegativity, will affect the electron cloud distribution of the benzene ring, which in turn affects the physical and chemical properties of the whole molecule. The hydrochloride form enhances the solubility of the compound in polar solvents.
What are the main uses of 3-chlorobenzenecarboximidamide Hydrochloride?
3-Chlorobenzamidine hydrochloride has a wide range of uses. In the field of pharmaceutical synthesis, it is often a key intermediate. Due to the structural properties of benzene rings with chlorine atoms, amidine groups and hydrochloride salts, it can participate in a variety of chemical reactions to construct compounds with specific biological activities. The preparation of many antibacterial and anti-inflammatory drugs relies on it as a starting material. By condensation and substitution with other reagents, the target drug molecule is obtained through delicate steps.
In the field of materials science, it is also useful. It can be used to prepare functional polymer materials. Due to the reactive groups in its structure, it can react with polymer monomers, giving the material special properties, such as improving the surface hydrophilicity of the material and enhancing the mechanical properties of the material. In addition, in the synthesis of dyes, 3-chlorobenzamidine hydrochloride can contribute a unique chemical structure, participate in the construction of dye molecules, endow dyes with specific colors and dyeing properties, and meet the needs of different textile and printing industries. In short, 3-chlorobenzamidine hydrochloride plays an important role in many fields of chemical industry, and its unique structural characteristics promote the development and innovation of various fields.
In the field of materials science, it is also useful. It can be used to prepare functional polymer materials. Due to the reactive groups in its structure, it can react with polymer monomers, giving the material special properties, such as improving the surface hydrophilicity of the material and enhancing the mechanical properties of the material. In addition, in the synthesis of dyes, 3-chlorobenzamidine hydrochloride can contribute a unique chemical structure, participate in the construction of dye molecules, endow dyes with specific colors and dyeing properties, and meet the needs of different textile and printing industries. In short, 3-chlorobenzamidine hydrochloride plays an important role in many fields of chemical industry, and its unique structural characteristics promote the development and innovation of various fields.
What are the physical properties of 3-chlorobenzenecarboximidamide Hydrochloride?
3 - chlorobenzenecarboximidamide hydrochloride (3-chlorobenzamidine hydrochloride), its physical properties are as follows.
This is a white to off-white crystalline powder, which is fine in appearance. Under normal temperature and pressure, the properties are quite stable. Its melting point is usually in a specific range, about [X] ° C. This melting point is one of the important physical indicators for identifying the substance, which can be accurately measured by a melting point tester.
Its solubility is also a key physical property. In water, this substance exhibits a certain solubility and can form a uniform solution, but its solubility is not infinite, depending on temperature and other conditions. In organic solvents, such as ethanol, acetone, etc., the solubility varies. In ethanol, the degree of solubility is relatively considerable, and it can be mutually soluble with ethanol in a certain proportion. However, in some non-polar organic solvents, such as n-hexane, the solubility is poor.
In addition, 3-chlorobenzamidine hydrochloride has hygroscopicity. If placed in a high humidity environment, it can absorb moisture in the air, causing its own properties to change, or from a dry powder to a slightly moist state. In severe cases, it may even agglomerate. Therefore, it is necessary to pay attention to moisture-proof when storing, and it is often sealed and stored in a dry place. Its density is also one of the inherent physical properties. Although the exact value needs to be determined by professional instruments, the approximate density range can be used as a reference for identifying and distinguishing the substance. Overall, various physical properties are crucial for the understanding and application of 3-chlorobenzamidine hydrochloride.
This is a white to off-white crystalline powder, which is fine in appearance. Under normal temperature and pressure, the properties are quite stable. Its melting point is usually in a specific range, about [X] ° C. This melting point is one of the important physical indicators for identifying the substance, which can be accurately measured by a melting point tester.
Its solubility is also a key physical property. In water, this substance exhibits a certain solubility and can form a uniform solution, but its solubility is not infinite, depending on temperature and other conditions. In organic solvents, such as ethanol, acetone, etc., the solubility varies. In ethanol, the degree of solubility is relatively considerable, and it can be mutually soluble with ethanol in a certain proportion. However, in some non-polar organic solvents, such as n-hexane, the solubility is poor.
In addition, 3-chlorobenzamidine hydrochloride has hygroscopicity. If placed in a high humidity environment, it can absorb moisture in the air, causing its own properties to change, or from a dry powder to a slightly moist state. In severe cases, it may even agglomerate. Therefore, it is necessary to pay attention to moisture-proof when storing, and it is often sealed and stored in a dry place. Its density is also one of the inherent physical properties. Although the exact value needs to be determined by professional instruments, the approximate density range can be used as a reference for identifying and distinguishing the substance. Overall, various physical properties are crucial for the understanding and application of 3-chlorobenzamidine hydrochloride.
What is the preparation method of 3-chlorobenzenecarboximidamide Hydrochloride?
The preparation of 3-chlorobenzamidine hydrochloride is an important task in chemical synthesis. Its preparation follows many methods, one of which is described in this article.
First, 3-chlorobenzoic acid is taken as the starting material and placed in a reactor together with dichlorosulfoxide. Dichlorosulfoxide is a chlorination reagent, which can convert the carboxyl group of benzoic acid into acyl chloride. This reaction requires temperature control, usually under moderate heating, so that the two can fully react. Usually between 50 and 80 ° C, when the number of reactions, there is no obvious gas escape from the reaction solution, which means that the conversion of carboxyl groups to acyl chloride is nearly complete.
Then, the obtained 3-chlorobenzoyl chloride is slowly dripped into the reaction system containing excess anhydrous ammonia at low temperature and stirred. Ammonia reacts with acyl chloride to form 3-chlorobenzamide. In this step, the temperature should be controlled at 0-10 ° C to prevent side reactions from occurring. After adding the droplets, keep stirring at low temperature for a period of time to ensure the complete reaction.
Mix 3-chlorobenzamide with phosphorus pentachloride and react at an appropriate temperature. Phosphorus pentachloride is a dehydrating agent, which can promote the dehydration of amides into amidines. The reaction temperature is about 120-150 ℃. After several reactions, 3-chlorobenzamidine can be obtained.
Finally, 3-chlorobenzamidine is dissolved in an appropriate amount of organic solvent, such as ethanol, and dried hydrogen chloride gas is introduced. Hydrogen chloride reacts with 3-chlorobenzamidine to form 3-chlorobenzamidine hydrochloride. After the reaction is complete, the pure 3-chlorobenzamidine hydrochloride product can be obtained after cooling, crystallization, filtration, drying and other post-processing steps.
In this preparation method, the precise control of the reaction conditions at each step, such as temperature, reactant ratio, reaction time, etc., is related to the purity and yield of the product, and requires careful operation.
First, 3-chlorobenzoic acid is taken as the starting material and placed in a reactor together with dichlorosulfoxide. Dichlorosulfoxide is a chlorination reagent, which can convert the carboxyl group of benzoic acid into acyl chloride. This reaction requires temperature control, usually under moderate heating, so that the two can fully react. Usually between 50 and 80 ° C, when the number of reactions, there is no obvious gas escape from the reaction solution, which means that the conversion of carboxyl groups to acyl chloride is nearly complete.
Then, the obtained 3-chlorobenzoyl chloride is slowly dripped into the reaction system containing excess anhydrous ammonia at low temperature and stirred. Ammonia reacts with acyl chloride to form 3-chlorobenzamide. In this step, the temperature should be controlled at 0-10 ° C to prevent side reactions from occurring. After adding the droplets, keep stirring at low temperature for a period of time to ensure the complete reaction.
Mix 3-chlorobenzamide with phosphorus pentachloride and react at an appropriate temperature. Phosphorus pentachloride is a dehydrating agent, which can promote the dehydration of amides into amidines. The reaction temperature is about 120-150 ℃. After several reactions, 3-chlorobenzamidine can be obtained.
Finally, 3-chlorobenzamidine is dissolved in an appropriate amount of organic solvent, such as ethanol, and dried hydrogen chloride gas is introduced. Hydrogen chloride reacts with 3-chlorobenzamidine to form 3-chlorobenzamidine hydrochloride. After the reaction is complete, the pure 3-chlorobenzamidine hydrochloride product can be obtained after cooling, crystallization, filtration, drying and other post-processing steps.
In this preparation method, the precise control of the reaction conditions at each step, such as temperature, reactant ratio, reaction time, etc., is related to the purity and yield of the product, and requires careful operation.
What is the market outlook for 3-chlorobenzenecarboximidamide Hydrochloride?
3-Chlorobenzamidine hydrochloride is an important compound in the field of organic chemistry. In the current market situation, its prospects contain many aspects.
In the field of pharmaceutical synthesis, in recent years, with the increasing demand for specific active molecules in pharmaceutical research and development, 3-chlorobenzamidine hydrochloride is often used as a key intermediate. In many new drug development projects, it is necessary to build a unique chemical structure to endow drugs with specific pharmacological activities. For example, some anti-parasitic drugs and antibacterial drugs are indispensable, so the demand for the pharmaceutical industry is on the rise.
In the field of pesticides, with the popularization of green and efficient pesticide concepts, the structure of pesticides containing 3-chlorobenzamidine hydrochloride has attracted attention. Because it can introduce pesticide molecules through specific reactions, improve the biological activity and selectivity of pesticides to targets, and reduce the impact on non-target organisms, it is in line with the current development trend of pesticides. It is expected that the market share will expand significantly in the future.
From the perspective of market competition, with the expansion of its application, it has attracted many chemical companies to enter production. The market supply is gradually sufficient, but the quality is uneven. Enterprises with advanced production processes and strict quality control can produce high-purity and stable quality products, gain an advantage in market competition, and are more likely to win long-term orders from downstream customers.
Furthermore, with the tightening of environmental protection supervision, 3-chlorobenzamidine hydrochloride production enterprises must follow strict environmental protection standards. The research and development of green synthetic process enterprises can not only meet environmental protection requirements, but also reduce production costs, and have a broader market prospect in the future.
Overall, the market prospect of 3-chlorobenzamidine hydrochloride is promising. However, enterprises need to cope with competition and environmental protection challenges, and seize market opportunities through technological innovation and quality improvement.
In the field of pharmaceutical synthesis, in recent years, with the increasing demand for specific active molecules in pharmaceutical research and development, 3-chlorobenzamidine hydrochloride is often used as a key intermediate. In many new drug development projects, it is necessary to build a unique chemical structure to endow drugs with specific pharmacological activities. For example, some anti-parasitic drugs and antibacterial drugs are indispensable, so the demand for the pharmaceutical industry is on the rise.
In the field of pesticides, with the popularization of green and efficient pesticide concepts, the structure of pesticides containing 3-chlorobenzamidine hydrochloride has attracted attention. Because it can introduce pesticide molecules through specific reactions, improve the biological activity and selectivity of pesticides to targets, and reduce the impact on non-target organisms, it is in line with the current development trend of pesticides. It is expected that the market share will expand significantly in the future.
From the perspective of market competition, with the expansion of its application, it has attracted many chemical companies to enter production. The market supply is gradually sufficient, but the quality is uneven. Enterprises with advanced production processes and strict quality control can produce high-purity and stable quality products, gain an advantage in market competition, and are more likely to win long-term orders from downstream customers.
Furthermore, with the tightening of environmental protection supervision, 3-chlorobenzamidine hydrochloride production enterprises must follow strict environmental protection standards. The research and development of green synthetic process enterprises can not only meet environmental protection requirements, but also reduce production costs, and have a broader market prospect in the future.
Overall, the market prospect of 3-chlorobenzamidine hydrochloride is promising. However, enterprises need to cope with competition and environmental protection challenges, and seize market opportunities through technological innovation and quality improvement.
Scan to WhatsApp
