Linshang Chemical
PRODUCTS
3-(Chloromethyl)-1,2,4,5-Tetrafluorobenzene
Linshang Chemical
|
HS Code |
928527 |
| Chemical Formula | C7H2ClF4 |
| Molecular Weight | 198.54 |
| Appearance | Liquid (usually) |
| Boiling Point | Data needed |
| Melting Point | Data needed |
| Density | Data needed |
| Solubility In Water | Low (organic compound) |
| Vapor Pressure | Data needed |
| Flash Point | Data needed |
| Refractive Index | Data needed |
As an accredited 3-(Chloromethyl)-1,2,4,5-Tetrafluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 mL bottle containing 3-(chloromethyl)-1,2,4,5 - tetrafluorobenzene, well - sealed. |
| Storage | Store 3-(chloromethyl)-1,2,4,5 - tetrafluorobenzene in a cool, dry, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Isolate it from oxidizing agents and incompatible substances. Label the storage clearly to avoid misidentification. |
| Shipping | 3-(Chloromethyl)-1,2,4,5 - tetrafluorobenzene is shipped in accordance with strict chemical regulations. Packed in suitable, secure containers, transported by approved carriers to ensure safe handling and delivery. |
Competitive 3-(Chloromethyl)-1,2,4,5-Tetrafluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 3-(Chloromethyl)-1,2,4,5-Tetrafluorobenzene in China?
As a trusted 3-(Chloromethyl)-1,2,4,5-Tetrafluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3-(Chloromethyl)-1,2,4,5-Tetrafluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 3- (chloromethyl) -1,2,4, 5-tetrafluorobenzene
3- (chloromethyl) - 1,2,4,5-tetrafluorobenzene is one of the organic compounds. Its main use involves the field of organic synthesis.
In the field of organic synthesis, this compound is often used as a key intermediate. Due to its unique structure, chloromethyl coexists with tetrafluorobenzene ring, giving it special reactivity. Chloromethyl can undergo many nucleophilic substitution reactions, such as interacting with nucleophiles containing nitrogen, oxygen, sulfur, etc., introducing different functional groups, and then building a multi-component organic molecular structure.
For example, it can react with alcohols under basic conditions to form ether products. In this reaction, the oxygen negative ion of the alcohol attacks the carbon atom of the chloromethyl group, and the chloride ion leaves, resulting in ether substances. The tetrafluorobenzene ring part, due to the electron-absorbing effect of fluorine atoms, can regulate the electron cloud distribution of molecules, affecting the reactivity and selectivity.
Furthermore, in the construction of complex drug molecular structures, 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene can be used as a starting material, and through multi-step reactions, a molecular skeleton with specific biological activities can be gradually built. It also has potential applications in the field of materials science, or can be used to prepare polymer materials with special properties. By polymerizing with other monomers, it imparts special properties such as corrosion resistance and heat resistance. In short, it plays a significant role in organic synthesis and related fields, and is an important cornerstone for the creation of new organic compounds and materials.
In the field of organic synthesis, this compound is often used as a key intermediate. Due to its unique structure, chloromethyl coexists with tetrafluorobenzene ring, giving it special reactivity. Chloromethyl can undergo many nucleophilic substitution reactions, such as interacting with nucleophiles containing nitrogen, oxygen, sulfur, etc., introducing different functional groups, and then building a multi-component organic molecular structure.
For example, it can react with alcohols under basic conditions to form ether products. In this reaction, the oxygen negative ion of the alcohol attacks the carbon atom of the chloromethyl group, and the chloride ion leaves, resulting in ether substances. The tetrafluorobenzene ring part, due to the electron-absorbing effect of fluorine atoms, can regulate the electron cloud distribution of molecules, affecting the reactivity and selectivity.
Furthermore, in the construction of complex drug molecular structures, 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene can be used as a starting material, and through multi-step reactions, a molecular skeleton with specific biological activities can be gradually built. It also has potential applications in the field of materials science, or can be used to prepare polymer materials with special properties. By polymerizing with other monomers, it imparts special properties such as corrosion resistance and heat resistance. In short, it plays a significant role in organic synthesis and related fields, and is an important cornerstone for the creation of new organic compounds and materials.
What are the physical properties of 3- (chloromethyl) -1,2,4, 5-tetrafluorobenzene
3 - (chloromethyl) - 1, 2, 4, 5 - tetrafluorobenzene is one of the organic compounds. Its physical properties are quite well researched.
Looking at its physical state, under normal temperature and pressure, this substance may be in a liquid state. Due to the characteristics of its molecular structure, the intermolecular force reaches this state. This liquid state makes it a good solvent for the reactants in various chemical reactions, because it can dissolve many organic substances, provide a uniform environment for the reaction, and make the reactant molecules more accessible, thereby promoting the reaction.
As for its color, it is often colorless and transparent. This pure phase is convenient for experimenters to observe related reaction phenomena. Because it is colorless and does not interfere with the observation of color changes during the reaction process, it is of great significance for chemical analysis and the exploration of reaction mechanisms.
When it comes to odor, 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene often has a special odor. The generation of this odor is closely related to the type of atoms in the molecule and the way of connection. Although it is difficult to accurately describe this odor, its special smell can be used as one of the characteristics to identify the substance. And this odor may stimulate the human senses, so careful protection is required when exposed to this substance.
Then again, the density of 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene may be different from that of water. Its density is determined by the relative mass of the molecules and the degree of arrangement between the molecules. This density characteristic is quite critical in operations such as mixture separation. If mixed with water, according to the density difference, its position in the stratification phenomenon can be known, so that the preliminary separation can be achieved.
The boiling point is also one of its important physical properties. Due to the existence of van der Waals forces between molecules and the special effects of fluorine atoms, 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene has a specific boiling point. Knowing this boiling point, in separation and purification operations such as distillation, the temperature can be precisely controlled to effectively separate it from the mixture to obtain a pure product.
In terms of solubility, due to the presence of fluorine atoms and other groups in its molecular structure, it exhibits a certain solubility in organic solvents, such as ethanol, ether, etc. This solubility property not only facilitates its use as a reactant or intermediate in organic synthesis, but also serves as a consideration in the selection of suitable solvents when analyzing and separating substances.
In summary, the physical properties of 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene are of great significance in chemical research, industrial production and related application fields, providing a basic basis for the development of many operations and reactions.
Looking at its physical state, under normal temperature and pressure, this substance may be in a liquid state. Due to the characteristics of its molecular structure, the intermolecular force reaches this state. This liquid state makes it a good solvent for the reactants in various chemical reactions, because it can dissolve many organic substances, provide a uniform environment for the reaction, and make the reactant molecules more accessible, thereby promoting the reaction.
As for its color, it is often colorless and transparent. This pure phase is convenient for experimenters to observe related reaction phenomena. Because it is colorless and does not interfere with the observation of color changes during the reaction process, it is of great significance for chemical analysis and the exploration of reaction mechanisms.
When it comes to odor, 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene often has a special odor. The generation of this odor is closely related to the type of atoms in the molecule and the way of connection. Although it is difficult to accurately describe this odor, its special smell can be used as one of the characteristics to identify the substance. And this odor may stimulate the human senses, so careful protection is required when exposed to this substance.
Then again, the density of 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene may be different from that of water. Its density is determined by the relative mass of the molecules and the degree of arrangement between the molecules. This density characteristic is quite critical in operations such as mixture separation. If mixed with water, according to the density difference, its position in the stratification phenomenon can be known, so that the preliminary separation can be achieved.
The boiling point is also one of its important physical properties. Due to the existence of van der Waals forces between molecules and the special effects of fluorine atoms, 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene has a specific boiling point. Knowing this boiling point, in separation and purification operations such as distillation, the temperature can be precisely controlled to effectively separate it from the mixture to obtain a pure product.
In terms of solubility, due to the presence of fluorine atoms and other groups in its molecular structure, it exhibits a certain solubility in organic solvents, such as ethanol, ether, etc. This solubility property not only facilitates its use as a reactant or intermediate in organic synthesis, but also serves as a consideration in the selection of suitable solvents when analyzing and separating substances.
In summary, the physical properties of 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene are of great significance in chemical research, industrial production and related application fields, providing a basic basis for the development of many operations and reactions.
What are the synthesis methods of 3- (chloromethyl) -1,2,4, 5-tetrafluorobenzene
The synthesis method of 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene is a very important topic in the field of organic synthesis. There are many synthetic paths, and each has its own advantages and disadvantages. It is necessary to choose the best one according to the actual situation.
One is the halogenated hydrocarbon substitution method. Suitable halogenated reagents can be selected to react with benzene derivatives containing corresponding substituents. For example, tetrafluorobenzene is used as the starting material, and under specific reaction conditions, it is made to react with chloromethylating reagents. This process requires precise control of the reaction temperature, time and proportion of reactants. If the temperature is too high, it may cause side reactions and reduce the purity of the product; if the temperature is too low, the reaction rate will be delayed and the yield will be affected. Through fine regulation of these parameters, chloromethyl can successfully replace the specific hydrogen atom on the benzene ring to obtain the target product.
Second, nucleophilic substitution method. This is based on the attack of nucleophilic test agents on substrates. Select reagents with appropriate nucleophilic properties to react with pre-designed substrate molecules. In the synthesis of 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene, the substrate structure can be cleverly designed, so that the nucleophilic reagents can accurately attack the target check point and achieve the introduction of chloromethyl. This method requires strict reaction conditions. Factors such as the polarity of the solvent and the strength of the base have a profound impact on the reaction process and product yield. Therefore, the reaction conditions must be carefully screened to ensure the smooth progress of the reaction.
Third, metal catalysis method. With the unique activity of metal catalysts, the reaction can be effectively promoted. In the presence of some metal catalysts, the related reactants can take novel reaction paths to generate the target product. The advantage of this method is the high selectivity of the catalyst, which can effectively avoid unnecessary side reactions and improve the purity of the product. However, the cost of metal catalysts is usually high, and recycling and reuse are also issues to be considered. Therefore, in practical application, cost and benefit need to be weighed.
In short, there are various methods for synthesizing 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene, and the advantages and disadvantages of each method coexist. In actual synthesis, chemists need to consider many factors such as raw material cost, reaction conditions, product purity and yield, and carefully select the most suitable synthesis route to achieve the goal of efficient, economical and environmentally friendly synthesis.
One is the halogenated hydrocarbon substitution method. Suitable halogenated reagents can be selected to react with benzene derivatives containing corresponding substituents. For example, tetrafluorobenzene is used as the starting material, and under specific reaction conditions, it is made to react with chloromethylating reagents. This process requires precise control of the reaction temperature, time and proportion of reactants. If the temperature is too high, it may cause side reactions and reduce the purity of the product; if the temperature is too low, the reaction rate will be delayed and the yield will be affected. Through fine regulation of these parameters, chloromethyl can successfully replace the specific hydrogen atom on the benzene ring to obtain the target product.
Second, nucleophilic substitution method. This is based on the attack of nucleophilic test agents on substrates. Select reagents with appropriate nucleophilic properties to react with pre-designed substrate molecules. In the synthesis of 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene, the substrate structure can be cleverly designed, so that the nucleophilic reagents can accurately attack the target check point and achieve the introduction of chloromethyl. This method requires strict reaction conditions. Factors such as the polarity of the solvent and the strength of the base have a profound impact on the reaction process and product yield. Therefore, the reaction conditions must be carefully screened to ensure the smooth progress of the reaction.
Third, metal catalysis method. With the unique activity of metal catalysts, the reaction can be effectively promoted. In the presence of some metal catalysts, the related reactants can take novel reaction paths to generate the target product. The advantage of this method is the high selectivity of the catalyst, which can effectively avoid unnecessary side reactions and improve the purity of the product. However, the cost of metal catalysts is usually high, and recycling and reuse are also issues to be considered. Therefore, in practical application, cost and benefit need to be weighed.
In short, there are various methods for synthesizing 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene, and the advantages and disadvantages of each method coexist. In actual synthesis, chemists need to consider many factors such as raw material cost, reaction conditions, product purity and yield, and carefully select the most suitable synthesis route to achieve the goal of efficient, economical and environmentally friendly synthesis.
3- (chloromethyl) -1,2,4, 5-tetrafluorobenzene what to pay attention to when storing and transporting
3 - (chloromethyl) - 1,2,4,5 - tetrafluorobenzene is a chemical substance, and many matters need to be carefully paid attention to during storage and transportation.
First words storage. This substance should be placed in a cool, dry and well-ventilated place. A cool environment can prevent its chemical properties from mutating due to excessive temperature to prevent danger. A dry place can prevent it from coming into contact with water vapor, because some chemicals will react in contact with water, or cause deterioration, or produce harmful substances. In a well-ventilated place, if it volatilizes harmful gases, it can be quickly dispersed and will not accumulate.
Furthermore, the storage place should be away from fire and heat sources. This substance may be flammable. In case of open flames or hot topics, it is very easy to ignite and explode, endangering safety. It should also be stored separately from oxidants, acids, alkalis, etc. Because of its chemical activity, it is easy to react violently when mixed with various substances.
As for transportation, it is necessary to ensure that the packaging is in good condition. If the packaging is damaged, the material leaks, and the pollution of the environment is still small, which will cause a major safety accident. The transportation process should be stable and prevent bumps and collisions to avoid damage to the packaging. The transportation tools should also be clean, and there should be no residual other chemical substances to avoid mutual reaction.
Transportation personnel must undergo professional training and be familiar with the characteristics of this substance and emergency treatment methods. If there is a leak during transportation, it can be handled quickly and correctly to minimize the harm. Therefore, when storing and transporting 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene, careful attention should be paid to all items to ensure safety.
First words storage. This substance should be placed in a cool, dry and well-ventilated place. A cool environment can prevent its chemical properties from mutating due to excessive temperature to prevent danger. A dry place can prevent it from coming into contact with water vapor, because some chemicals will react in contact with water, or cause deterioration, or produce harmful substances. In a well-ventilated place, if it volatilizes harmful gases, it can be quickly dispersed and will not accumulate.
Furthermore, the storage place should be away from fire and heat sources. This substance may be flammable. In case of open flames or hot topics, it is very easy to ignite and explode, endangering safety. It should also be stored separately from oxidants, acids, alkalis, etc. Because of its chemical activity, it is easy to react violently when mixed with various substances.
As for transportation, it is necessary to ensure that the packaging is in good condition. If the packaging is damaged, the material leaks, and the pollution of the environment is still small, which will cause a major safety accident. The transportation process should be stable and prevent bumps and collisions to avoid damage to the packaging. The transportation tools should also be clean, and there should be no residual other chemical substances to avoid mutual reaction.
Transportation personnel must undergo professional training and be familiar with the characteristics of this substance and emergency treatment methods. If there is a leak during transportation, it can be handled quickly and correctly to minimize the harm. Therefore, when storing and transporting 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene, careful attention should be paid to all items to ensure safety.
What is the effect of 3- (chloromethyl) -1,2,4, 5-tetrafluorobenzene on the environment?
3 - (chloromethyl) - 1, 2, 4, 5 - tetrafluorobenzene is an organic compound. Its impact on the environment is related to ecology and human health, and it is a matter of great importance.
Among this compound, the structure of chloromethyl and tetrafluorobenzene ring gives it specific physical and chemical properties. Its impact on the environment, the first to bear the brunt, is accumulated in the organisms of the ecosystem. Because it has a certain lipid solubility, it is easy for organisms to ingest, and then pass and accumulate in the food chain. Such as plankton in water, if this compound is present in the environment, it is easy to ingest it. Then the small fish eat the plankton, and the big fish eat the small fish. This compound is then enriched in the big fish and eventually affects the advanced organisms.
Furthermore, it may interfere with the physiological functions of the organism. The presence of chloromethyl and fluorine atoms may cause it to interact with biological macromolecules such as proteins and nucleic acids in the organism. For example, it may change the conformation of the protein, impair its function, and affect the metabolism, immunity and many other physiological processes of the organism. In the case of plants, it may interfere with the key steps of photosynthesis and hinder the growth and development of plants.
In addition, 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene degrades slowly in the environment. Due to its special chemical structure, the general natural degradation pathway is difficult to work, causing it to remain in soil and water for a long time. This not only occupies environmental space, but also continues to put pressure on the surrounding ecological environment.
If it enters the atmosphere, it will also affect the atmospheric environment. Or participate in complex chemical reactions in the atmosphere, change the chemical composition of the atmosphere, affect air quality, and indirectly cause harm to the respiratory system of humans and other organisms. Therefore, this compound needs to be treated with caution, and its production, use and emission should be strictly controlled to protect the safety of the environment and maintain ecological balance.
Among this compound, the structure of chloromethyl and tetrafluorobenzene ring gives it specific physical and chemical properties. Its impact on the environment, the first to bear the brunt, is accumulated in the organisms of the ecosystem. Because it has a certain lipid solubility, it is easy for organisms to ingest, and then pass and accumulate in the food chain. Such as plankton in water, if this compound is present in the environment, it is easy to ingest it. Then the small fish eat the plankton, and the big fish eat the small fish. This compound is then enriched in the big fish and eventually affects the advanced organisms.
Furthermore, it may interfere with the physiological functions of the organism. The presence of chloromethyl and fluorine atoms may cause it to interact with biological macromolecules such as proteins and nucleic acids in the organism. For example, it may change the conformation of the protein, impair its function, and affect the metabolism, immunity and many other physiological processes of the organism. In the case of plants, it may interfere with the key steps of photosynthesis and hinder the growth and development of plants.
In addition, 3- (chloromethyl) -1,2,4,5-tetrafluorobenzene degrades slowly in the environment. Due to its special chemical structure, the general natural degradation pathway is difficult to work, causing it to remain in soil and water for a long time. This not only occupies environmental space, but also continues to put pressure on the surrounding ecological environment.
If it enters the atmosphere, it will also affect the atmospheric environment. Or participate in complex chemical reactions in the atmosphere, change the chemical composition of the atmosphere, affect air quality, and indirectly cause harm to the respiratory system of humans and other organisms. Therefore, this compound needs to be treated with caution, and its production, use and emission should be strictly controlled to protect the safety of the environment and maintain ecological balance.
Scan to WhatsApp
