Linshang Chemical
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3-Chlorosulfonylbenzenesulfonyl Chloride
Linshang Chemical
|
HS Code |
921309 |
| Chemical Formula | C6H4Cl2O4S2 |
| Molecular Weight | 275.13 |
| Appearance | Colorless to light yellow liquid |
| Odor | Pungent |
| Density | 1.66 g/cm³ |
| Boiling Point | 160 - 162 °C at 1.5 mmHg |
| Melting Point | 14 - 16 °C |
| Solubility | Reacts with water, soluble in organic solvents like dichloromethane |
| Stability | Stable under normal conditions, but reacts with water and bases |
| Hazard Class | Corrosive |
As an accredited 3-Chlorosulfonylbenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 3 - chlorosulfonylbenzenesulfonyl Chloride in sealed, corrosion - resistant container. |
| Storage | 3 - Chlorosulfonylbenzenesulfonyl Chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent contact with moisture, which can cause decomposition. Store it separately from incompatible substances like bases, reducing agents, and water - reactive materials to avoid dangerous reactions. |
| Shipping | 3 - Chlorosulfonylbenzenesulfonyl chloride, a hazardous chemical, must be shipped in tightly - sealed, corrosion - resistant containers. It should be labeled properly, transported under regulated conditions to prevent spills and ensure safety during transit. |
Competitive 3-Chlorosulfonylbenzenesulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 3-Chlorosulfonylbenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemistry of 3-chlorosulfonylbenzenesulfonyl Chloride?
3-Chlorosulfonylbenzenesulfonyl chloride, this is an organic compound. Its chemical properties are quite unique and have strong chemical activity.
Looking at its structure, it contains chlorine atoms and sulfonyl chloride groups, which give the substance unique reactivity. Sulfonyl chloride groups are very active and easily participate in a variety of chemical reactions.
In nucleophilic substitution reactions, the chlorine atoms of sulfonyl chloride groups are vulnerable to attack by nucleophiles, such as nucleophiles such as alcohols and amines. In case of alcohols, a substitution reaction can occur to form sulfonate compounds. This reaction is often used in organic synthesis to prepare esters with specific structures. If it meets with amines, sulfonamide products are formed, which is a common method for synthesizing sulfonamide drugs or functional materials.
Furthermore, because it contains chlorine atoms, under specific conditions, it can participate in the reaction involving chlorine atoms. For example, under the catalysis of some metals, chlorine atoms can undergo coupling reactions and connect with other organic fragments to build more complex organic molecular structures.
However, this compound also has many points to pay attention to. Due to its high chemical activity, caution must be taken when storing and handling. It is prone to hydrolysis in contact with water, and the sulfonyl chloride group will react with water to form the corresponding sulfonic acid and hydrogen chloride gas. Therefore, it is necessary to ensure that the environment is dry during storage, and the operation should also be carried out under anhydrous conditions to prevent unnecessary reactions from occurring, causing safety hazards or affecting the experimental results.
Looking at its structure, it contains chlorine atoms and sulfonyl chloride groups, which give the substance unique reactivity. Sulfonyl chloride groups are very active and easily participate in a variety of chemical reactions.
In nucleophilic substitution reactions, the chlorine atoms of sulfonyl chloride groups are vulnerable to attack by nucleophiles, such as nucleophiles such as alcohols and amines. In case of alcohols, a substitution reaction can occur to form sulfonate compounds. This reaction is often used in organic synthesis to prepare esters with specific structures. If it meets with amines, sulfonamide products are formed, which is a common method for synthesizing sulfonamide drugs or functional materials.
Furthermore, because it contains chlorine atoms, under specific conditions, it can participate in the reaction involving chlorine atoms. For example, under the catalysis of some metals, chlorine atoms can undergo coupling reactions and connect with other organic fragments to build more complex organic molecular structures.
However, this compound also has many points to pay attention to. Due to its high chemical activity, caution must be taken when storing and handling. It is prone to hydrolysis in contact with water, and the sulfonyl chloride group will react with water to form the corresponding sulfonic acid and hydrogen chloride gas. Therefore, it is necessary to ensure that the environment is dry during storage, and the operation should also be carried out under anhydrous conditions to prevent unnecessary reactions from occurring, causing safety hazards or affecting the experimental results.
What are the main uses of 3-chlorosulfonylbenzenesulfonyl Chloride?
3-Chlorosulfonylbenzenesulfonyl chloride is a crucial raw material in the field of organic synthesis and has a wide range of uses.
First, in the field of pharmaceutical synthesis, it can act as a key intermediate. The unique structure of the genbenzene ring and the sulfonyl chloride group endows it with the ability to participate in many chemical reactions and can be used to construct complex drug molecular structures. For example, by substitution reactions with nucleophiles containing nitrogen and oxygen, specific functional groups can be introduced to synthesize compounds with specific pharmacological activities, which play an important role in the development of new antibacterial, anti-tumor and other drugs.
Second, in the field of materials science, it also has important uses. It can be used as a modifier to chemically modify polymer materials. For example, by reacting with the active check points on the polymer chain, the surface properties of the material can be changed, such as improving the hydrophilicity and fouling resistance of the material, thereby improving the performance of the material in coatings, fibers, etc.
Third, in the synthesis of pesticides, 3-chlorosulfonylbenzenesulfonyl chloride is also indispensable. With its participation in the reaction, pesticides with high insecticidal and herbicidal properties can be prepared. Through precise structural design and reaction regulation, pesticides with high selectivity for specific pests or weeds can be synthesized, which can not only improve the effect of pesticides, but also reduce the impact on the environment.
Fourth, in the field of dye synthesis, it can be used as a starting material for the synthesis of special structural dyes. Using its active chemical properties, dye molecules with specific colors and stability can be constructed to meet the needs of high-quality dyes in textile, printing and dyeing industries. Because the chlorine atoms and sulfonyl chloride groups in the structure can be modified by chemical reactions, a wide variety of dye products with different properties can be synthesized.
First, in the field of pharmaceutical synthesis, it can act as a key intermediate. The unique structure of the genbenzene ring and the sulfonyl chloride group endows it with the ability to participate in many chemical reactions and can be used to construct complex drug molecular structures. For example, by substitution reactions with nucleophiles containing nitrogen and oxygen, specific functional groups can be introduced to synthesize compounds with specific pharmacological activities, which play an important role in the development of new antibacterial, anti-tumor and other drugs.
Second, in the field of materials science, it also has important uses. It can be used as a modifier to chemically modify polymer materials. For example, by reacting with the active check points on the polymer chain, the surface properties of the material can be changed, such as improving the hydrophilicity and fouling resistance of the material, thereby improving the performance of the material in coatings, fibers, etc.
Third, in the synthesis of pesticides, 3-chlorosulfonylbenzenesulfonyl chloride is also indispensable. With its participation in the reaction, pesticides with high insecticidal and herbicidal properties can be prepared. Through precise structural design and reaction regulation, pesticides with high selectivity for specific pests or weeds can be synthesized, which can not only improve the effect of pesticides, but also reduce the impact on the environment.
Fourth, in the field of dye synthesis, it can be used as a starting material for the synthesis of special structural dyes. Using its active chemical properties, dye molecules with specific colors and stability can be constructed to meet the needs of high-quality dyes in textile, printing and dyeing industries. Because the chlorine atoms and sulfonyl chloride groups in the structure can be modified by chemical reactions, a wide variety of dye products with different properties can be synthesized.
What is the synthesis method of 3-chlorosulfonylbenzenesulfonyl Chloride?
To prepare 3-chlorosulfonyl benzenesulfonyl chloride, the method is as follows:
Take benzene as the starting material and sulfonate it with fuming sulfuric acid. This reaction requires a specific temperature and duration to fully interact with benzene and fuming sulfuric acid. The hydrogen atom on the benzene ring is replaced by a sulfonyl group to obtain benzenesulfonic acid.
Next, the benzenesulfonic acid is co-heated with phosphorus pentachloride. Phosphorus pentachloride is a strong chlorination agent. Under heating conditions, the sulfonic acid group in the benzenesulfonic acid reacts with phosphorus pentachloride, and the hydroxyl group on the sulfonic acid group is replaced by a
Then chlorine is introduced into benzenesulfonyl chloride. In the environment of light or catalyst, chlorine atoms can selectively replace hydrogen atoms at specific positions on the benzene ring. After fine regulation of the reaction conditions, the chlorine atoms are replaced at the position adjacent to the sulfonyl chloride group, and 3-chlorosulfonylbenzenesulfonyl chloride is finally obtained.
In this preparation process, each step of the reaction requires strict control of temperature, reactant ratio and reaction time to improve the purity and yield of the product. And safety must be paid attention to during operation, because the fuming sulfuric acid and phosphorus pentachloride used are highly corrosive and irritating.
Take benzene as the starting material and sulfonate it with fuming sulfuric acid. This reaction requires a specific temperature and duration to fully interact with benzene and fuming sulfuric acid. The hydrogen atom on the benzene ring is replaced by a sulfonyl group to obtain benzenesulfonic acid.
Next, the benzenesulfonic acid is co-heated with phosphorus pentachloride. Phosphorus pentachloride is a strong chlorination agent. Under heating conditions, the sulfonic acid group in the benzenesulfonic acid reacts with phosphorus pentachloride, and the hydroxyl group on the sulfonic acid group is replaced by a
Then chlorine is introduced into benzenesulfonyl chloride. In the environment of light or catalyst, chlorine atoms can selectively replace hydrogen atoms at specific positions on the benzene ring. After fine regulation of the reaction conditions, the chlorine atoms are replaced at the position adjacent to the sulfonyl chloride group, and 3-chlorosulfonylbenzenesulfonyl chloride is finally obtained.
In this preparation process, each step of the reaction requires strict control of temperature, reactant ratio and reaction time to improve the purity and yield of the product. And safety must be paid attention to during operation, because the fuming sulfuric acid and phosphorus pentachloride used are highly corrosive and irritating.
What are the precautions for 3-chlorosulfonylbenzenesulfonyl Chloride in storage and transportation?
3-Chlorosulfonylbenzenesulfonyl chloride is one of the chemical substances. When storing and transporting, be sure to pay attention to many matters.
This substance is highly corrosive and easily reacts violently in contact with water, releasing irritating gases such as hydrogen chloride. Therefore, when storing, it should be placed in a dry, cool and well-ventilated place, away from fire and heat sources to prevent it from being dangerous due to heat. It must be stored separately from alkalis, alcohols, active metal powders, etc., and must not be mixed. The lid is prone to chemical reactions due to its encounter with these substances, resulting in danger.
As for transportation, be sure to ensure that the packaging is complete and the loading is secure before transportation. During transportation, it is necessary to ensure that the container does not leak, collapse, fall or damage. The route should avoid densely populated areas and residential areas. Transportation vehicles must be equipped with corresponding types and quantities of fire-fighting equipment and leakage emergency treatment equipment. If a leak occurs during transportation, drivers and passengers must quickly evacuate to a safe area, and irrelevant personnel are strictly prohibited from approaching the contaminated area. Emergency responders must wear protective clothing and gas masks, do not let the leak come into contact with combustible substances, and contain the leak with appropriate materials such as sand and dry lime, and then dispose of it properly.
In short, the storage and transportation of 3-chlorosulfonyl benzenesulfonyl chloride should be handled with caution and in strict accordance with relevant safety procedures, so as to ensure the safety of personnel and the environment from pollution.
This substance is highly corrosive and easily reacts violently in contact with water, releasing irritating gases such as hydrogen chloride. Therefore, when storing, it should be placed in a dry, cool and well-ventilated place, away from fire and heat sources to prevent it from being dangerous due to heat. It must be stored separately from alkalis, alcohols, active metal powders, etc., and must not be mixed. The lid is prone to chemical reactions due to its encounter with these substances, resulting in danger.
As for transportation, be sure to ensure that the packaging is complete and the loading is secure before transportation. During transportation, it is necessary to ensure that the container does not leak, collapse, fall or damage. The route should avoid densely populated areas and residential areas. Transportation vehicles must be equipped with corresponding types and quantities of fire-fighting equipment and leakage emergency treatment equipment. If a leak occurs during transportation, drivers and passengers must quickly evacuate to a safe area, and irrelevant personnel are strictly prohibited from approaching the contaminated area. Emergency responders must wear protective clothing and gas masks, do not let the leak come into contact with combustible substances, and contain the leak with appropriate materials such as sand and dry lime, and then dispose of it properly.
In short, the storage and transportation of 3-chlorosulfonyl benzenesulfonyl chloride should be handled with caution and in strict accordance with relevant safety procedures, so as to ensure the safety of personnel and the environment from pollution.
3-chlorosulfonylbenzenesulfonyl Chloride Effects on the Environment and Human Health
3-Chlorosulfonylbenzenesulfonyl chloride has many effects on the environment and human health.
In terms of the environment, it may be quite harmful. If it escapes into the soil, it may change the soil properties, affect the reproduction and activity of soil microorganisms, and then interfere with the uptake of nutrients by plant roots, hindering plant growth. Its flow into the water body will cause the water quality to deteriorate, which is quite toxic to aquatic organisms, or will disrupt the balance of aquatic ecosystems, causing the death or reproduction of fish, shellfish and other organisms. In the long run, it will affect the entire aquatic ecological chain. And because of its active chemical properties, it may also participate in complex chemical reactions in the atmosphere, affecting air quality.
As for human health, its harm should not be underestimated. If the human body inhales through the respiratory tract, it will strongly irritate the respiratory mucosa, causing symptoms such as cough, asthma, breathing difficulties, long-term exposure, or cause lung diseases, such as chronic obstructive pulmonary disease. If skin contact, it can cause serious burns, redness, swelling, blisters, ulceration, etc. Improper handling can easily lead to infection. Once eaten by mistake, it will corrode the digestive tract, damage the gastrointestinal mucosa, cause severe pain, vomiting, diarrhea, etc., and in serious cases, it is life-threatening.
These chemicals need to be properly disposed of and used. They must not be ignored because of their subtle potential harm to the environment and human health. Be cautious and strictly abide by the operating norms to prevent problems before they occur.
In terms of the environment, it may be quite harmful. If it escapes into the soil, it may change the soil properties, affect the reproduction and activity of soil microorganisms, and then interfere with the uptake of nutrients by plant roots, hindering plant growth. Its flow into the water body will cause the water quality to deteriorate, which is quite toxic to aquatic organisms, or will disrupt the balance of aquatic ecosystems, causing the death or reproduction of fish, shellfish and other organisms. In the long run, it will affect the entire aquatic ecological chain. And because of its active chemical properties, it may also participate in complex chemical reactions in the atmosphere, affecting air quality.
As for human health, its harm should not be underestimated. If the human body inhales through the respiratory tract, it will strongly irritate the respiratory mucosa, causing symptoms such as cough, asthma, breathing difficulties, long-term exposure, or cause lung diseases, such as chronic obstructive pulmonary disease. If skin contact, it can cause serious burns, redness, swelling, blisters, ulceration, etc. Improper handling can easily lead to infection. Once eaten by mistake, it will corrode the digestive tract, damage the gastrointestinal mucosa, cause severe pain, vomiting, diarrhea, etc., and in serious cases, it is life-threatening.
These chemicals need to be properly disposed of and used. They must not be ignored because of their subtle potential harm to the environment and human health. Be cautious and strictly abide by the operating norms to prevent problems before they occur.
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