Linshang Chemical
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3-Nitro-1,2,4,5-Tetrachlorobenzene
Linshang Chemical
|
HS Code |
906211 |
| Chemical Formula | C6HCl4NO2 |
| Molar Mass | 277.89 g/mol |
| Appearance | Solid |
| Solubility In Water | Low (due to non - polar nature of benzene ring and hydrophobic substituents) |
| Solubility In Organic Solvents | Soluble in common organic solvents like benzene, toluene |
| Stability | Stable under normal conditions but may react under extreme conditions |
| Hazardous Nature | Toxic, may cause harm to health and environment due to halogen and nitro groups |
As an accredited 3-Nitro-1,2,4,5-Tetrachlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 3 - nitro - 1,2,4,5 - tetrachlorobenzene packaged in air - tight chemical - grade containers. |
| Storage | 3 - nitro - 1,2,4,5 - tetrachlorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from sources of ignition and heat. Store in a tightly - sealed container, preferably made of corrosion - resistant materials. Isolate it from incompatible substances like oxidizing agents, reducing agents, and bases to prevent chemical reactions and potential hazards. |
| Shipping | 3 - nitro - 1,2,4,5 - tetrachlorobenzene is likely shipped in specialized, corrosion - resistant containers. It must comply with strict hazardous chemical shipping regulations, ensuring proper labeling and safety measures during transport. |
Competitive 3-Nitro-1,2,4,5-Tetrachlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 3-Nitro-1,2,4,5-Tetrachlorobenzene in China?
As a trusted 3-Nitro-1,2,4,5-Tetrachlorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3-Nitro-1,2,4,5-Tetrachlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 3-nitro-1,2,4, 5-tetrachlorobenzene
3-Nitro-1,2,4,5-tetrachlorobenzene has specific properties. Looking at it, this is an organic halide, containing several nitro and chlorine atoms. The nitro group has strong electron absorption, and the chlorine atom also has an electronic effect. The combination of the two makes its reactivity different.
Talking about chemical activity, in the nucleophilic substitution reaction, the nitro group can reduce the electron cloud density of the benzene ring, making the chlorine atom easier to attack by the nucleophilic reagent. When the nucleophilic reagent approaches the benzene ring, the nitro group can stabilize the reaction intermediate by means of the conjugation effect and promote the reaction.
And it is oxidizing, and the nitro group can be reduced, such as in a suitable reducing agent, the nitro group or the amino group. This reduction reaction is commonly used in organic synthesis to produce aromatic amines.
In addition, its solubility also has characteristics. Because it is an organic molecule with polar groups nitro and halogen atoms, it may have a certain solubility in polar organic solvents such as acetone and acetonitrile, but has a slight solubility in water. Because the polarity of water is different from the structure of the organic substance, it is difficult to dissolve.
In addition, its stability is related to the reaction conditions. Under extreme conditions such as high temperature, strong base or strong acid, it may cause molecular structural changes, such as dehalogenation reaction or nitro conversion. At room temperature and under normal conditions, it is relatively stable, and can still react when exposed to active reagents, showing its unique chemistry. It is useful in organic synthesis, material chemistry and other fields, and can be used as an intermediate to produce a variety of complex organic compounds.
Talking about chemical activity, in the nucleophilic substitution reaction, the nitro group can reduce the electron cloud density of the benzene ring, making the chlorine atom easier to attack by the nucleophilic reagent. When the nucleophilic reagent approaches the benzene ring, the nitro group can stabilize the reaction intermediate by means of the conjugation effect and promote the reaction.
And it is oxidizing, and the nitro group can be reduced, such as in a suitable reducing agent, the nitro group or the amino group. This reduction reaction is commonly used in organic synthesis to produce aromatic amines.
In addition, its solubility also has characteristics. Because it is an organic molecule with polar groups nitro and halogen atoms, it may have a certain solubility in polar organic solvents such as acetone and acetonitrile, but has a slight solubility in water. Because the polarity of water is different from the structure of the organic substance, it is difficult to dissolve.
In addition, its stability is related to the reaction conditions. Under extreme conditions such as high temperature, strong base or strong acid, it may cause molecular structural changes, such as dehalogenation reaction or nitro conversion. At room temperature and under normal conditions, it is relatively stable, and can still react when exposed to active reagents, showing its unique chemistry. It is useful in organic synthesis, material chemistry and other fields, and can be used as an intermediate to produce a variety of complex organic compounds.
What are the uses of 3-nitro-1,2,4, 5-tetrachlorobenzene
3-Nitro-1,2,4,5-tetrachlorobenzene, that is, 3-nitro-1,2,4,5-tetrachlorobenzene, is widely used. In the field of chemical synthesis, it is often used as a key intermediate. It can be converted into a variety of compounds with special properties through specific chemical reactions. For example, in the preparation of some high-value-added pesticide ingredients, 3-nitro-1,2,4,5-tetrachlorobenzene plays an indispensable role, which can give pesticides more excellent insecticidal and herbicidal effects.
Furthermore, in the field of materials science, it is also useful. Using this as a raw material, new materials with special electrical, optical or thermal properties can be synthesized. For example, in the development of some organic optoelectronic materials, the introduction of 3-nitro-1,2,4,5-tetrachlorobenzene structural units can optimize the charge transport and luminescence properties of the materials, providing a boost for the development of new display technologies and optoelectronic devices.
In addition, in the field of pharmaceutical chemistry, although not directly used as drugs, it can provide an important structural template for drug development. Through structural modification and derivatization of it, it is expected to discover lead compounds with potential biological activities, and then lay the foundation for the creation of innovative drugs. In short, 3-nitro-1,2,4,5-tetrachlorobenzene has shown important application value in many fields due to its unique chemical structure, promoting technological progress and development in various related fields.
Furthermore, in the field of materials science, it is also useful. Using this as a raw material, new materials with special electrical, optical or thermal properties can be synthesized. For example, in the development of some organic optoelectronic materials, the introduction of 3-nitro-1,2,4,5-tetrachlorobenzene structural units can optimize the charge transport and luminescence properties of the materials, providing a boost for the development of new display technologies and optoelectronic devices.
In addition, in the field of pharmaceutical chemistry, although not directly used as drugs, it can provide an important structural template for drug development. Through structural modification and derivatization of it, it is expected to discover lead compounds with potential biological activities, and then lay the foundation for the creation of innovative drugs. In short, 3-nitro-1,2,4,5-tetrachlorobenzene has shown important application value in many fields due to its unique chemical structure, promoting technological progress and development in various related fields.
What are the effects of 3-nitro-1,2,4, 5-tetrachlorobenzene on the environment?
3-Nitro-1,2,4,5-tetrachlorobenzene is an organic halide and has a profound impact on the environment.
Its toxicity, if released in nature, organisms bear the brunt. In the aquatic domain, it can harm fish, turtles, shrimp and crabs and other aquatic species, hinder their growth and reproduction, and even cause their premature death. In the terrestrial environment, it can enter the soil, pests, earthworms and other organisms, breaking the balance of soil ecology.
And this compound has high stability and is difficult to degrade in the environment. Long-term accumulation, or into the food chain. Initially, it is ingested by microorganisms, and gradually reaches higher organisms, including humans. The internal accumulation of the human body can damage the viscera and immune system, causing health worries, such as increased risk of cancer, and the nervous and reproductive systems are also harmed.
In the atmosphere, if it evaporates, or becomes a raw material for photochemical smog, it will damage the air quality and irritate people's breathing, eyes and eyes. When precipitation falls, it can fall into the soil and water bodies with rain, and then expand the area of pollution.
In addition, its production, use and disposal process, or waste water, waste gas, waste residue generation, if not properly disposed of, are all environmental hazards.
Therefore, the control and monitoring of 3-nitro-1,2,4,5-tetrachlorobenzene should be strictly carried out to prevent it from escaping into the environment, ensuring ecological safety and the health of all living beings.
Its toxicity, if released in nature, organisms bear the brunt. In the aquatic domain, it can harm fish, turtles, shrimp and crabs and other aquatic species, hinder their growth and reproduction, and even cause their premature death. In the terrestrial environment, it can enter the soil, pests, earthworms and other organisms, breaking the balance of soil ecology.
And this compound has high stability and is difficult to degrade in the environment. Long-term accumulation, or into the food chain. Initially, it is ingested by microorganisms, and gradually reaches higher organisms, including humans. The internal accumulation of the human body can damage the viscera and immune system, causing health worries, such as increased risk of cancer, and the nervous and reproductive systems are also harmed.
In the atmosphere, if it evaporates, or becomes a raw material for photochemical smog, it will damage the air quality and irritate people's breathing, eyes and eyes. When precipitation falls, it can fall into the soil and water bodies with rain, and then expand the area of pollution.
In addition, its production, use and disposal process, or waste water, waste gas, waste residue generation, if not properly disposed of, are all environmental hazards.
Therefore, the control and monitoring of 3-nitro-1,2,4,5-tetrachlorobenzene should be strictly carried out to prevent it from escaping into the environment, ensuring ecological safety and the health of all living beings.
What is the preparation method of 3-nitro-1,2,4, 5-tetrachlorobenzene
To prepare 3-nitro-1,2,4,5-tetrachlorobenzene, you can do the following.
First take 1,2,4,5-tetrachlorobenzene as the starting material. In a suitable reaction vessel, add an appropriate amount of 1,2,4,5-tetrachlorobenzene, which is the substrate for the reaction.
Next, take concentrated nitric acid and concentrated sulfuric acid to prepare a mixed acid. Concentrated sulfuric acid here, one is a dehydrating agent, and the other can protonate nitric acid and enhance the electrophilicity of nitric acid. When mixing acid, it is advisable to slowly pour concentrated sulfuric acid into concentrated nitric acid and stir it continuously to prevent overheating and danger.
Add the mixed acid dropwise to a reaction vessel containing 1,2,4,5-tetrachlorobenzene under the condition of low temperature and stirring. Because the nitrification reaction is exothermic, the low temperature can effectively control the temperature and prevent side reactions from occurring. Generally speaking, the reaction temperature can be maintained between 0-10 ° C.
During the process of dropwise addition of mixed acid, continuous stirring is required to make the reactants fully contact, so that the reaction can proceed uniformly. After the mixed acid is added dropwise, it can be moderately warmed to room temperature, and the reaction number of times is continued to stir, so that the reaction tends to be complete.
After the reaction is completed, the reaction liquid is poured into ice water, and precipitation is precipitated. This is because the product 3 - nitro - 1,2,4,5 - tetrachlorobenzene has little solubility in water.
Then the precipitation is collected by filtration. After that, the precipitation is repeatedly washed with an appropriate amount of water to remove the inclusion acid.
Finally, the product is recrystallized with a suitable organic solvent to improve the purity of the product. After drying, pure 3 - nitro - 1,2,4,5 - tetrachlorobenzene can be obtained.
During the whole preparation process, attention should be paid to safety. Because the mixed acid is highly corrosive and the nitrification reaction is an exothermic reaction, the temperature should be accurately controlled and properly operated.
First take 1,2,4,5-tetrachlorobenzene as the starting material. In a suitable reaction vessel, add an appropriate amount of 1,2,4,5-tetrachlorobenzene, which is the substrate for the reaction.
Next, take concentrated nitric acid and concentrated sulfuric acid to prepare a mixed acid. Concentrated sulfuric acid here, one is a dehydrating agent, and the other can protonate nitric acid and enhance the electrophilicity of nitric acid. When mixing acid, it is advisable to slowly pour concentrated sulfuric acid into concentrated nitric acid and stir it continuously to prevent overheating and danger.
Add the mixed acid dropwise to a reaction vessel containing 1,2,4,5-tetrachlorobenzene under the condition of low temperature and stirring. Because the nitrification reaction is exothermic, the low temperature can effectively control the temperature and prevent side reactions from occurring. Generally speaking, the reaction temperature can be maintained between 0-10 ° C.
During the process of dropwise addition of mixed acid, continuous stirring is required to make the reactants fully contact, so that the reaction can proceed uniformly. After the mixed acid is added dropwise, it can be moderately warmed to room temperature, and the reaction number of times is continued to stir, so that the reaction tends to be complete.
After the reaction is completed, the reaction liquid is poured into ice water, and precipitation is precipitated. This is because the product 3 - nitro - 1,2,4,5 - tetrachlorobenzene has little solubility in water.
Then the precipitation is collected by filtration. After that, the precipitation is repeatedly washed with an appropriate amount of water to remove the inclusion acid.
Finally, the product is recrystallized with a suitable organic solvent to improve the purity of the product. After drying, pure 3 - nitro - 1,2,4,5 - tetrachlorobenzene can be obtained.
During the whole preparation process, attention should be paid to safety. Because the mixed acid is highly corrosive and the nitrification reaction is an exothermic reaction, the temperature should be accurately controlled and properly operated.
What are the precautions for 3-nitro-1,2,4, 5-tetrachlorobenzene in storage and transportation?
3-Nitro-1,2,4,5-tetrachlorobenzene is a potentially dangerous chemical substance. When storing and transporting, the following things must be paid attention to:
First, the storage place must be selected in a cool, dry and well-ventilated place. This is because the substance is heated or damp, it may change its chemical properties and even cause dangerous reactions. For example, if stored in a humid place, moisture may react with the substance, damage its structure, and form harmful substances.
Second, it must be stored separately from oxidants, reducing agents, acids, bases, etc., and must not be mixed. Due to its lively chemical properties, it is easy to trigger violent chemical reactions when it encounters the above-mentioned substances, such as combustion, explosion and other serious accidents.
Third, choose the appropriate material for the storage container and ensure that it is well sealed. Generally speaking, corrosion-resistant metal or plastic containers should be used. If the container material is improper or the seal is not good, the substance may leak out, pollute the environment and endanger personal safety.
Fourth, when transporting, be sure to strictly abide by the relevant transportation regulations and standards. Transportation vehicles should be equipped with corresponding emergency treatment equipment and protective equipment for emergencies. And during transportation, avoid vehicle bumps and vibrations that are too violent to prevent damage to the container.
Fifth, whether it is storage or transportation, special personnel need to be arranged for management and monitoring. When managers are familiar with the characteristics of the substance and emergency treatment methods, they can quickly and correctly take measures to reduce the harm when it is convenient for emergencies.
In short, for the storage and transportation of 3-nitro-1,2,4,5-tetrachlorobenzene, care must be taken and strict regulations must be followed to ensure the safety of personnel and the environment are not damaged.
First, the storage place must be selected in a cool, dry and well-ventilated place. This is because the substance is heated or damp, it may change its chemical properties and even cause dangerous reactions. For example, if stored in a humid place, moisture may react with the substance, damage its structure, and form harmful substances.
Second, it must be stored separately from oxidants, reducing agents, acids, bases, etc., and must not be mixed. Due to its lively chemical properties, it is easy to trigger violent chemical reactions when it encounters the above-mentioned substances, such as combustion, explosion and other serious accidents.
Third, choose the appropriate material for the storage container and ensure that it is well sealed. Generally speaking, corrosion-resistant metal or plastic containers should be used. If the container material is improper or the seal is not good, the substance may leak out, pollute the environment and endanger personal safety.
Fourth, when transporting, be sure to strictly abide by the relevant transportation regulations and standards. Transportation vehicles should be equipped with corresponding emergency treatment equipment and protective equipment for emergencies. And during transportation, avoid vehicle bumps and vibrations that are too violent to prevent damage to the container.
Fifth, whether it is storage or transportation, special personnel need to be arranged for management and monitoring. When managers are familiar with the characteristics of the substance and emergency treatment methods, they can quickly and correctly take measures to reduce the harm when it is convenient for emergencies.
In short, for the storage and transportation of 3-nitro-1,2,4,5-tetrachlorobenzene, care must be taken and strict regulations must be followed to ensure the safety of personnel and the environment are not damaged.
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