Linshang Chemical
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3-Nitro-4-Chloro-4'-Acetamido Benzene Sulfonamide
Linshang Chemical
|
HS Code |
472720 |
| Chemical Formula | C8H8ClN3O5S |
| Molar Mass | 295.68 g/mol |
| Appearance | Solid |
| Physical State At Room Temperature | Solid |
| Color | Typically white to off - white |
| Odor | May have a faint, characteristic odor |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Soluble in some polar organic solvents |
| Melting Point | Reportedly in a certain range (data - specific value needed) |
| Density | Data - specific value needed |
| Stability | Stable under normal conditions but may react with strong oxidizing agents |
As an accredited 3-Nitro-4-Chloro-4'-Acetamido Benzene Sulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 3 - nitro - 4 - chloro - 4’ - acetamido Benzene Sulfonamide in sealed chemical - grade bags. |
| Storage | 3 - nitro - 4 - chloro - 4’ - acetamido Benzene Sulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and incompatible substances. Store in a tightly closed container to prevent moisture absorption and potential chemical reactions, safeguarding its chemical integrity and minimizing risks. |
| Shipping | 3 - nitro - 4 - chloro - 4’ - acetamido Benzene Sulfonamide is a chemical. Shipping should follow strict hazardous materials regulations. It must be properly packaged, labeled, and transported by carriers approved for such chemicals. |
Competitive 3-Nitro-4-Chloro-4'-Acetamido Benzene Sulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 3-Nitro-4-Chloro-4'-Acetamido Benzene Sulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 3-nitro-4-chloro-4 '-acetamido Benzene Sulfonamide?
The chemical structure of 3-nitro-4-chloro-4 '-acetamido Benzene Sulfonamide is particularly complex. This compound contains a benzene ring. Above the benzene ring, there is a nitro group ($NO_2 $) in the third position, and a chlorine atom ($Cl $) in the fourth position.
and in the para-position (4' position) of the benzene ring, there is an acetamido group ($CH_3CONH - $). There is also a sulfonamido group ($- SO_2NH_2 $) connected to the benzene ring.
Overall, the benzene ring is the core skeleton in its structure, and the nitro group, chlorine atom, acetamide group and sulfonamide group are all its substituents. The groups are arranged in specific positions and interact with each other to determine the chemical properties and reactivity of the compound. This structure makes the compound have unique application and research value in organic synthesis, pharmaceutical chemistry and other fields. The electronic and spatial effects of its different substituents also have significant effects on its physical and chemical properties, such as solubility, melting point, boiling point, etc.
and in the para-position (4' position) of the benzene ring, there is an acetamido group ($CH_3CONH - $). There is also a sulfonamido group ($- SO_2NH_2 $) connected to the benzene ring.
Overall, the benzene ring is the core skeleton in its structure, and the nitro group, chlorine atom, acetamide group and sulfonamide group are all its substituents. The groups are arranged in specific positions and interact with each other to determine the chemical properties and reactivity of the compound. This structure makes the compound have unique application and research value in organic synthesis, pharmaceutical chemistry and other fields. The electronic and spatial effects of its different substituents also have significant effects on its physical and chemical properties, such as solubility, melting point, boiling point, etc.
What are the main uses of 3-nitro-4-chloro-4 '-acetamido Benzene Sulfonamide?
3-Nitro-4-chloro-4 '-acetamido Benzene Sulfonamide is an organic compound. Its main use is related to the field of medicine and chemical industry.
In the field of medicine, this compound may be involved in the preparation of antibacterial drugs. Given the characteristics of its chemical structure, it can affect the physiological process of specific pathogens. It can interfere with the metabolic pathway of pathogens, such as inhibiting the activity of some key enzymes, making it difficult for pathogens to grow and multiply normally, and then exert antibacterial effects, providing assistance for the treatment of infectious diseases.
In the field of chemical industry, it may be an important synthetic intermediate. Through various chemical reactions, it can be combined with other compounds to form more complex organic molecular structures. On this basis, a variety of chemical products with different functions can be prepared, such as dyes and additives with special properties. Because their structures contain functional groups such as nitro, chlorine atoms, acetamide groups and benzenesulfonamide groups, these functional groups give them unique reactivity and chemical properties, which can participate in many organic synthesis reactions and expand the diversity and functionality of chemical products.
In short, 3-nitro-4-chloro-4 '-acetamido Benzene Sulfonamide has considerable uses in the fields of medicine and chemical industry, and plays an indispensable role in promoting the development of related industries.
In the field of medicine, this compound may be involved in the preparation of antibacterial drugs. Given the characteristics of its chemical structure, it can affect the physiological process of specific pathogens. It can interfere with the metabolic pathway of pathogens, such as inhibiting the activity of some key enzymes, making it difficult for pathogens to grow and multiply normally, and then exert antibacterial effects, providing assistance for the treatment of infectious diseases.
In the field of chemical industry, it may be an important synthetic intermediate. Through various chemical reactions, it can be combined with other compounds to form more complex organic molecular structures. On this basis, a variety of chemical products with different functions can be prepared, such as dyes and additives with special properties. Because their structures contain functional groups such as nitro, chlorine atoms, acetamide groups and benzenesulfonamide groups, these functional groups give them unique reactivity and chemical properties, which can participate in many organic synthesis reactions and expand the diversity and functionality of chemical products.
In short, 3-nitro-4-chloro-4 '-acetamido Benzene Sulfonamide has considerable uses in the fields of medicine and chemical industry, and plays an indispensable role in promoting the development of related industries.
What are the physical properties of 3-nitro-4-chloro-4 '-acetamido Benzene Sulfonamide?
3-Nitro-4-chloro-4 '-acetamidobenzenesulfonamide, this material has special properties and is characterized by color and taste. The color may be white to yellowish powder, which is delicate when viewed, and quite textured when viewed by the eye. Smell it, or have a weak specific smell, but it is not pungent and difficult to tolerate.
Its melting point is also an important physical property. The melting point is in a specific range, about [X] ° C. When this temperature is reached, the substance gradually melts from solid to liquid. This process is smooth and orderly, which is its inherent property. The boiling point is related to its gasification conditions. Under a certain pressure, when it reaches [Y] ° C, it will turn into gaseous rise.
Solubility is also the key. In water, its solubility is limited, only slightly soluble, and the interaction between water molecules and the molecules of the substance is weak. However, in organic solvents, such as alcohols and ethers, the dissolution situation is different. In alcohols, it can show a moderate state of dissolution, and the intermolecular force prompts it to disperse in the solvent system.
In terms of stability, in the normal environment, if the temperature and humidity are suitable, its chemical structure is relatively stable, and it is not easy to spontaneously produce significant changes. In case of strong acid and alkali, or high temperature and strong oxidation environment, its structure may be affected, triggering chemical reactions and causing chemical properties to change. These are all important physical properties of 3-nitro-4-chloro-4 '-acetamidobenzenesulfonamide, which are relied on for applications in many fields such as chemical industry and medicine.
Its melting point is also an important physical property. The melting point is in a specific range, about [X] ° C. When this temperature is reached, the substance gradually melts from solid to liquid. This process is smooth and orderly, which is its inherent property. The boiling point is related to its gasification conditions. Under a certain pressure, when it reaches [Y] ° C, it will turn into gaseous rise.
Solubility is also the key. In water, its solubility is limited, only slightly soluble, and the interaction between water molecules and the molecules of the substance is weak. However, in organic solvents, such as alcohols and ethers, the dissolution situation is different. In alcohols, it can show a moderate state of dissolution, and the intermolecular force prompts it to disperse in the solvent system.
In terms of stability, in the normal environment, if the temperature and humidity are suitable, its chemical structure is relatively stable, and it is not easy to spontaneously produce significant changes. In case of strong acid and alkali, or high temperature and strong oxidation environment, its structure may be affected, triggering chemical reactions and causing chemical properties to change. These are all important physical properties of 3-nitro-4-chloro-4 '-acetamidobenzenesulfonamide, which are relied on for applications in many fields such as chemical industry and medicine.
What is the synthesis method of 3-nitro-4-chloro-4 '-acetamido Benzene Sulfonamide?
To prepare 3-nitro-4-chloro-4 '-acetamido Benzene Sulfonamide, the method is as follows:
First take an appropriate starting material, with a benzene-based compound as the group, and the substituents on it need to be carefully arranged. Usually chlorine, nitro and groups that can be derived into acetamido and sulfonamide groups are used as the starting materials.
At the beginning of the reaction, nitro groups can be introduced by nitrification. The starting compound is placed in a suitable nitrification system, such as a mixed acid system of concentrated nitric acid and concentrated sulfuric acid, to control the reaction temperature, time and the ratio of reactants. If the temperature is too high, it is easy to cause excessive nitrification and produce polynitro by-products; if the temperature is too low, the reaction is slow and the yield is not good. Generally speaking, the temperature is maintained at a moderate low temperature, such as 0-10 ° C, and the mixed acid is slowly added dropwise. After several times of reaction, the intermediate product containing nitro groups can be obtained.
Then chlorine atoms are introduced, and chlorination is often used. Select the appropriate chlorination reagent according to the characteristics of the substrate, such as chlorine gas, thionyl chloride, etc. If chlorine gas is used as a chlorination agent, it needs to be carried out in the presence of light or an initiator, so that the chlorine atom can be precisely replaced in the desired position to obtain the product containing nitro and chlorine atoms.
After that, an acetamide group is constructed. A substituent on the benzene ring can be converted into an amino group with an appropriate reagent, and then the amino group can be reacted with an acetylating reagent, such as acetyl chloride or acetic anhydride, to form an This step requires attention to the reaction conditions to avoid excessive acetylation of other active checking points by acetylation reagents, which affects the purity of the product.
The last step is to form a sulfonamide group. The intermediate product containing nitro, chlorine atoms and acetamide groups is reacted with sulfonation reagents, such as fuming sulfuric acid, so that the benzene ring is introduced into the sulfonate group, and then the sulfonate group is treated with ammonia or amine compounds through aminolysis, and converted into a sulfonamide group to obtain the target product 3-nitro-4-chloro-4 '-acetamido Benzene Sulfonamide. The whole synthesis process needs to be carefully controlled for each step of the reaction, and attention should be paid to separation and purification to increase the purity and yield of the product.
First take an appropriate starting material, with a benzene-based compound as the group, and the substituents on it need to be carefully arranged. Usually chlorine, nitro and groups that can be derived into acetamido and sulfonamide groups are used as the starting materials.
At the beginning of the reaction, nitro groups can be introduced by nitrification. The starting compound is placed in a suitable nitrification system, such as a mixed acid system of concentrated nitric acid and concentrated sulfuric acid, to control the reaction temperature, time and the ratio of reactants. If the temperature is too high, it is easy to cause excessive nitrification and produce polynitro by-products; if the temperature is too low, the reaction is slow and the yield is not good. Generally speaking, the temperature is maintained at a moderate low temperature, such as 0-10 ° C, and the mixed acid is slowly added dropwise. After several times of reaction, the intermediate product containing nitro groups can be obtained.
Then chlorine atoms are introduced, and chlorination is often used. Select the appropriate chlorination reagent according to the characteristics of the substrate, such as chlorine gas, thionyl chloride, etc. If chlorine gas is used as a chlorination agent, it needs to be carried out in the presence of light or an initiator, so that the chlorine atom can be precisely replaced in the desired position to obtain the product containing nitro and chlorine atoms.
After that, an acetamide group is constructed. A substituent on the benzene ring can be converted into an amino group with an appropriate reagent, and then the amino group can be reacted with an acetylating reagent, such as acetyl chloride or acetic anhydride, to form an This step requires attention to the reaction conditions to avoid excessive acetylation of other active checking points by acetylation reagents, which affects the purity of the product.
The last step is to form a sulfonamide group. The intermediate product containing nitro, chlorine atoms and acetamide groups is reacted with sulfonation reagents, such as fuming sulfuric acid, so that the benzene ring is introduced into the sulfonate group, and then the sulfonate group is treated with ammonia or amine compounds through aminolysis, and converted into a sulfonamide group to obtain the target product 3-nitro-4-chloro-4 '-acetamido Benzene Sulfonamide. The whole synthesis process needs to be carefully controlled for each step of the reaction, and attention should be paid to separation and purification to increase the purity and yield of the product.
What are the precautions for using 3-nitro-4-chloro-4 '-acetamido Benzene Sulfonamide?
When using 3-nitro-4-chloro-4 '-acetamidobenzenesulfonamide, there are a number of urgent precautions that need to be paid attention to.
The first to bear the brunt is the end of safety protection. This compound contains nitro, chlorine and other groups, or may be toxic and irritating. When using it, be sure to wear appropriate protective equipment, such as laboratory clothes, gloves and goggles, to prevent it from contacting the skin and eyes. If it is accidentally touched, rinse it with plenty of water immediately, and decide whether to seek medical treatment according to the severity of the injury.
Furthermore, it is related to the operating environment. It is recommended to operate in a well-ventilated place to avoid the accumulation of dust or volatile gaseous substances in the air to prevent inhalation and damage to the respiratory system. And the place of operation should be away from fire and heat sources, because many compounds containing nitro groups are flammable and explosive, and a little carelessness will cause disasters.
Repeat, storage should not be ignored. It should be stored in a cool, dry and ventilated place, away from oxidants and reducing agents and other substances to prevent chemical reactions, causing deterioration or causing danger. Storage containers must be well sealed to prevent them from getting damp or reacting with ingredients in the air.
In addition, during use, the dosage should be precisely controlled. According to the specific experiment or production needs, accurately weigh the required amount to avoid the effect of too little dosage that does not meet expectations, nor waste caused by too much dosage, and excessive use may exacerbate the potential danger.
Finally, after use, the remaining materials and related waste must not be discarded at will. Proper disposal should be carried out in accordance with relevant regulations to prevent pollution to the environment. All of this is for those who should pay attention when using 3-nitro-4-chloro-4 '-acetamidolbenzenesulfonamide, and must be done with caution to ensure safety.
The first to bear the brunt is the end of safety protection. This compound contains nitro, chlorine and other groups, or may be toxic and irritating. When using it, be sure to wear appropriate protective equipment, such as laboratory clothes, gloves and goggles, to prevent it from contacting the skin and eyes. If it is accidentally touched, rinse it with plenty of water immediately, and decide whether to seek medical treatment according to the severity of the injury.
Furthermore, it is related to the operating environment. It is recommended to operate in a well-ventilated place to avoid the accumulation of dust or volatile gaseous substances in the air to prevent inhalation and damage to the respiratory system. And the place of operation should be away from fire and heat sources, because many compounds containing nitro groups are flammable and explosive, and a little carelessness will cause disasters.
Repeat, storage should not be ignored. It should be stored in a cool, dry and ventilated place, away from oxidants and reducing agents and other substances to prevent chemical reactions, causing deterioration or causing danger. Storage containers must be well sealed to prevent them from getting damp or reacting with ingredients in the air.
In addition, during use, the dosage should be precisely controlled. According to the specific experiment or production needs, accurately weigh the required amount to avoid the effect of too little dosage that does not meet expectations, nor waste caused by too much dosage, and excessive use may exacerbate the potential danger.
Finally, after use, the remaining materials and related waste must not be discarded at will. Proper disposal should be carried out in accordance with relevant regulations to prevent pollution to the environment. All of this is for those who should pay attention when using 3-nitro-4-chloro-4 '-acetamidolbenzenesulfonamide, and must be done with caution to ensure safety.
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