3-Nitro-4-Chloro Benzene Sulfonanilide
Linshang Chemical
HS Code |
494215 |
Chemical Formula | C6H3ClN2O4S |
Appearance | usually a solid |
Color | likely pale - colored |
Odor | may have a characteristic chemical odor |
Melting Point | specific value would need further research |
Boiling Point | specific value would need further research |
Solubility In Water | low solubility in water |
Solubility In Organic Solvents | soluble in some organic solvents |
Density | specific value would need further research |
Stability | stable under normal conditions, but may react with strong oxidizing agents |
Toxicity | toxic, may cause harm to health |
As an accredited 3-Nitro-4-Chloro Benzene Sulfonanilide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 3 - nitro - 4 - chloro Benzene Sulfonanilide in sealed, chemical - resistant bags. |
Storage | 3 - nitro - 4 - chloro Benzene Sulfonanilide should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container to prevent moisture and air exposure. Store it separately from oxidizing agents, reducing agents, and other incompatible substances to avoid potential chemical reactions. |
Shipping | 3 - nitro - 4 - chloro Benzene Sulfonanilide is shipped in well - sealed, corrosion - resistant containers. They are carefully packed to prevent breakage. Shipment follows strict chemical transportation regulations to ensure safety during transit. |
Competitive 3-Nitro-4-Chloro Benzene Sulfonanilide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 3-Nitro-4-Chloro Benzene Sulfonanilide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and reduce the electrophilic substitution activity of the benzene ring, but can enhance the reactivity of the adjacent and para-site groups. In this compound, it may affect the reaction of the chlorine atom and the sulfonylaniline part.
Chlorine atoms attached to the benzene ring can undergo nucleophilic substitution. When encountering nucleophilic reagents, such as compounds containing hydroxyl groups, amino groups, etc., under suitable conditions, chlorine atoms can be replaced to derive a variety of new compounds.
In the sulfonyl aniline group, the sulfonyl group has electron-absorbing properties and is connected to the aniline, which affects the electron cloud density of the aniline nitrogen atom and changes its alkalinity and reactivity. This group can participate in a variety of organic reactions, such as reacting with alcohols and amines to form new chemical bonds.
And this compound has a certain solubility in organic solvents because it contains multiple polar groups. Its polarity is related to the molecular structure, which affects the dispersion and reactivity in different solvent systems. In chemical reactions, each group affects each other, and the reaction conditions and product selectivity have specific rules. It is necessary to fine-tune the reaction conditions to obtain the desired product.
First, in the field of medicine, it is often used as a key intermediate. The drug synthesizes Dorai organic compounds and reacts with each other to build a specific chemical structure and achieve therapeutic effect. 3-Nitro-4-chlorobenzenesulfonaniline has a special chemical structure and can be converted into biologically active substances through a series of reactions. For example, when synthesizing some antibacterial drugs, this is used as the starting material. By modifying its structure, the drug can enhance the inhibition or killing ability of specific bacteria, so that the drug can accurately act on the target of bacteria, and then effectively treat infectious diseases.
Second, in terms of pesticides, it is also an important raw material. With the development of agriculture, the demand for high-efficiency, low-toxicity and environmentally friendly pesticides is increasing. 3-Nitro-4-chlorobenzenesulfonylaniline can participate in the synthesis of a variety of pesticides, such as insecticides, fungicides, etc. After rational design and reaction, the obtained pesticides can have a good control effect on crop diseases and insect pests. For example, the synthesis of specific insecticides can interfere with the nervous system or physiological metabolic processes of pests, kill pests efficiently, ensure crop yield and quality, and minimize the impact on the environment and non-target organisms.
Third, in the dye industry, it also plays an important role. Dyes need to have good color, stability and dyeing properties. 3-Nitro-4-chlorobenzenesulfonylaniline can provide unique chemical groups for dye synthesis, affecting the electron cloud distribution and structure of dye molecules, thereby giving dyes different colors and properties. After chemical modification and reaction, dyes with bright colors, light resistance and washing fastness can be synthesized to meet the needs of different colors and properties dyes in textile, printing and dyeing industries.
To make 3-nitro-4-chlorobenzenesulfonylaniline, you can first take an appropriate benzene, use chlorine as a agent, and replace the benzene with chlorine under suitable conditions. The ancient chemical industry, although there is no precise instrument today, can still be controlled by experience such as heat and time. When chlorination is done, a good medium needs to be found to make the reaction smooth. After 4-chlorobenzene is obtained, nitrogenation is carried out. The method of nitrogenation is to use saltpeter and other nitro-containing substances as the source, add other agents, adjust the environment, so that the nitro group enters the specific position of 4-chlorobenzene to obtain 3-nitro-4-chlorobenzene.
Then, 3-nitro-4-chlorobenzene is mixed with a sulfonylating reagent. The sulfonylating reagent, which is obtained from ancient or sulfur-containing minerals, is cleverly prepared to react with 3-nitro-4-chlorobenzene to form an intermediate of 3-nitro-4-chlorobenzenesulfonic acid.
Finally, 3-nitro-4-chlorobenzenesulfonic acid meets aniline. The two are reacted and combined in an appropriate medium to obtain 3-nitro-4-chlorobenzenesulfonylaniline. In this process, temperature, humidity, and the ratio of reactants are all key, and they need to be carefully controlled. Although there is no accurate measurement today, the ancient workers can also obtain the desired product with experience and skills.
First, when storing, you must choose a cool, dry and well-ventilated place. This is because if the substance is exposed to high temperature and humidity, it is afraid of qualitative change. I still remember in the past, there were potions that were stored in wet places, which greatly reduced their effectiveness. Therefore, it is necessary to avoid direct sunlight and isolate them from fires, heat sources, etc. to prevent unexpected risks, such as fires and explosions.
Second, during transportation, make sure that the packaging is intact. If the package is damaged, the material may leak out, which not only stains the surroundings, but also easily causes personnel to come into contact and cause injury. In the past, there were transportation accidents, the package broke, causing the material to leak out and involving everyone. This is a good lesson. The means of transportation used should also be clean, with no residue of other things, and avoid chemical reactions.
Third, the material may be toxic and irritating. People who store and transport it must wear suitable protective equipment, such as gloves, masks, goggles, etc., to protect themselves. Do not be negligent and neglect protection, which will put yourself in danger.
Fourth, the storage place should be equipped with corresponding emergency treatment equipment and suitable containment materials. In case of leakage, it can be dealt with quickly to reduce its harm. There were leaks in the past, but due to timely disposal, it did not cause a major disaster.
In general, the whole process of storage and transportation of 3-nitro-4-chlorobenzenesulfonylaniline needs to be carefully and strictly adhered to.
At the environmental end, if this compound is released into nature, it may affect soil, water and atmosphere. In soil, it may change the physical and chemical properties of soil, affect the community structure and function of soil microorganisms, cause soil ecological imbalance, and then affect the growth and development of plants. If it flows into water bodies, it may harm aquatic organisms. Because it has certain chemical activities, it may interfere with the physiological metabolism of aquatic organisms, causing their reproduction and growth to be blocked, and even cause biological death, destroying the balance of aquatic ecosystems. In the atmosphere, although its volatilization may be limited, it may affect air quality through complex atmospheric chemical reactions or other harmful derivatives.
As for human health, this compound may invade the human body through respiratory tract, skin contact or accidental ingestion. Its nitro and chlorine atoms and other structures may be toxic and potentially carcinogenic. After entering the body, it may interfere with the normal physiological and biochemical processes of the human body, damaging organs and tissues. If it affects the function of metabolic and detoxifying organs such as the liver and kidneys, causing abnormal liver and kidney function; or affecting the nervous system, causing headache, dizziness, fatigue and other uncomfortable symptoms. Long-term exposure to this compound environment may also increase the risk of cancer. Therefore, when manufacturing and using products containing this compound, we should exercise caution and take appropriate protective and handling measures to reduce its harm to the environment and human health.

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