Linshang Chemical
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3-Nitro-4-Chlorobenzenesulfonamide
Linshang Chemical
|
HS Code |
188567 |
| Chemical Formula | C6H3ClN2O4S |
| Molecular Weight | 236.62 g/mol |
| Appearance | Solid |
| Melting Point | 146 - 148 °C |
| Solubility In Water | Low |
| Solubility In Organic Solvents | Soluble in some organic solvents |
| Odor | Odorless (usually) |
| Color | White to off - white |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 3-Nitro-4-Chlorobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 3 - nitro - 4 - chlorobenzenesulfonamide packaged in a sealed plastic bag. |
| Storage | 3 - nitro - 4 - chlorobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and contamination. It should be separated from incompatible substances to avoid potential chemical reactions. |
| Shipping | 3 - nitro - 4 - chlorobenzenesulfonamide should be shipped in well - sealed, corrosion - resistant containers. Ensure proper labeling indicating its hazardous nature. Ship via approved carriers following all relevant chemical transport regulations. |
Competitive 3-Nitro-4-Chlorobenzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 3-Nitro-4-Chlorobenzenesulfonamide in China?
As a trusted 3-Nitro-4-Chlorobenzenesulfonamide manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 3-Nitro-4-Chlorobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 3-nitro-4-chlorobenzenesulfonamide?
3 - nitro - 4 - chlorobenzenesulfonamide is one of the organic compounds. Its chemical structure is unique, with benzene ring as the base, which is a common ring structure in organic chemistry, with stable characteristics.
Benzene ring, there are many functional groups connected. One is nitro (-NO 2), which is connected to the third position of the benzene ring. Nitro has strong electron absorption, which can affect the electron cloud density and reactivity of the benzene ring. The other is the chlorine atom (-Cl), located in the fourth position of the benzene ring. The chlorine atom also has a certain influence on the chemical properties of the benzene ring. Due to its electronegativity, it can change the distribution of the electron cloud at a specific location of the benzene ring.
In addition, there is a sulfonamide group (-SO _ 2O _ NH _ 2O) attached to the benzene ring. In the sulfonamide group, the sulfur atom is connected with two oxygen atoms by a double bond, and the complex is connected with the amino group (-NH _ 2O). This functional group gives the compound unique physical and chemical properties, which have attracted much attention in the fields of organic synthesis and medicinal chemistry.
In summary, the chemical structure of 3-nitro-4-chlorobenzenesulfonamide is composed of benzene ring, nitro group, chlorine atom and sulfonamide group. The interaction of each part endows the compound with unique chemical properties and reactivity.
Benzene ring, there are many functional groups connected. One is nitro (-NO 2), which is connected to the third position of the benzene ring. Nitro has strong electron absorption, which can affect the electron cloud density and reactivity of the benzene ring. The other is the chlorine atom (-Cl), located in the fourth position of the benzene ring. The chlorine atom also has a certain influence on the chemical properties of the benzene ring. Due to its electronegativity, it can change the distribution of the electron cloud at a specific location of the benzene ring.
In addition, there is a sulfonamide group (-SO _ 2O _ NH _ 2O) attached to the benzene ring. In the sulfonamide group, the sulfur atom is connected with two oxygen atoms by a double bond, and the complex is connected with the amino group (-NH _ 2O). This functional group gives the compound unique physical and chemical properties, which have attracted much attention in the fields of organic synthesis and medicinal chemistry.
In summary, the chemical structure of 3-nitro-4-chlorobenzenesulfonamide is composed of benzene ring, nitro group, chlorine atom and sulfonamide group. The interaction of each part endows the compound with unique chemical properties and reactivity.
What are the main uses of 3-nitro-4-chlorobenzenesulfonamide?
3 - nitro - 4 - chlorobenzenesulfonamide is one of the organic compounds. It has a wide range of uses and is often used as a raw material for antibacterial drugs in the field of medicine. The cover is important for pharmaceuticals because of its unique structure and certain antibacterial activity, which can effectively inhibit the growth and reproduction of some bacteria.
It is also used in pesticides. It can be used as an intermediate in pesticide synthesis to help prepare pesticide products with insecticidal and bactericidal effects to protect crops from pests and diseases, thereby improving crop yield and quality.
In the field of materials science, this compound can participate in the synthesis of special materials. For example, it is used to make some polymer materials with specific requirements for chemical stability and heat resistance, endowing the material with unique properties and expanding the application scenarios of the material.
Because of its active chemical properties, it can be converted into a variety of derivatives with different functions through a series of chemical reactions, thus providing rich raw materials and choices for organic synthetic chemistry and promoting the development of organic synthesis field. All of these are the main uses of 3-nitro-4-chlorobenzenesulfonamide.
It is also used in pesticides. It can be used as an intermediate in pesticide synthesis to help prepare pesticide products with insecticidal and bactericidal effects to protect crops from pests and diseases, thereby improving crop yield and quality.
In the field of materials science, this compound can participate in the synthesis of special materials. For example, it is used to make some polymer materials with specific requirements for chemical stability and heat resistance, endowing the material with unique properties and expanding the application scenarios of the material.
Because of its active chemical properties, it can be converted into a variety of derivatives with different functions through a series of chemical reactions, thus providing rich raw materials and choices for organic synthetic chemistry and promoting the development of organic synthesis field. All of these are the main uses of 3-nitro-4-chlorobenzenesulfonamide.
What is 3-nitro-4-chlorobenzenesulfonamide synthesis method?
3-Nitro-4-chlorobenzenesulfonamide is 3-nitro-4-chlorobenzenesulfonamide. The synthesis method is as follows:
First, 4-chlorobenzenesulfonamide is used as the starting material, which is the basis of the reaction. Place it in a suitable reaction vessel, such as a flask. Then, slowly add a nitrifying reagent to it. The commonly used nitrifying reagent is a mixture of concentrated nitric acid and concentrated sulfuric acid, which complement each other. Concentrated sulfuric acid has the effect of dehydration and catalysis, and promotes the decomposition of concentrated nitric acid to produce nitroyl positive ions (NO.
When adding nitrifying reagents, careful temperature control is required. In general, the reaction temperature should be maintained at a low temperature, such as between 0 and 5 degrees Celsius. This is because the nitrification reaction is quite violent. If the temperature is too high, it is easy to cause side reactions and cause impure products. In a low temperature environment, nitroyl positive ions (NO ²) can successfully attack specific positions on the 4-chlorobenzenesulfonamide benzene ring. Due to the positioning effect of chlorine atoms and sulfonamide groups on the benzene ring, nitroyl positive ions mainly attack the carbon atoms adjacent to the chlorine atoms, thereby generating 3-nitro-4-chlorobenzenesulfonamide. During the
reaction, constant stirring is required to ensure that the reactants are fully mixed and the reaction proceeds uniformly. After the reaction is completed, the reaction mixture is poured into ice water to stop the reaction and precipitate the product. Then, the solid product is separated by filtration. Then, the solid product is washed with water or a suitable organic solvent to remove impurities. Finally, the product is purified by recrystallization and other means to obtain pure 3-nitro-4-chlorobenzenesulfonamide.
The whole synthesis process is very critical to the control of the reaction conditions, such as temperature, reagent ratio, reaction time, etc., which will affect the yield and purity of the product. Only fine operation can achieve good synthesis results.
First, 4-chlorobenzenesulfonamide is used as the starting material, which is the basis of the reaction. Place it in a suitable reaction vessel, such as a flask. Then, slowly add a nitrifying reagent to it. The commonly used nitrifying reagent is a mixture of concentrated nitric acid and concentrated sulfuric acid, which complement each other. Concentrated sulfuric acid has the effect of dehydration and catalysis, and promotes the decomposition of concentrated nitric acid to produce nitroyl positive ions (NO.
When adding nitrifying reagents, careful temperature control is required. In general, the reaction temperature should be maintained at a low temperature, such as between 0 and 5 degrees Celsius. This is because the nitrification reaction is quite violent. If the temperature is too high, it is easy to cause side reactions and cause impure products. In a low temperature environment, nitroyl positive ions (NO ²) can successfully attack specific positions on the 4-chlorobenzenesulfonamide benzene ring. Due to the positioning effect of chlorine atoms and sulfonamide groups on the benzene ring, nitroyl positive ions mainly attack the carbon atoms adjacent to the chlorine atoms, thereby generating 3-nitro-4-chlorobenzenesulfonamide. During the
reaction, constant stirring is required to ensure that the reactants are fully mixed and the reaction proceeds uniformly. After the reaction is completed, the reaction mixture is poured into ice water to stop the reaction and precipitate the product. Then, the solid product is separated by filtration. Then, the solid product is washed with water or a suitable organic solvent to remove impurities. Finally, the product is purified by recrystallization and other means to obtain pure 3-nitro-4-chlorobenzenesulfonamide.
The whole synthesis process is very critical to the control of the reaction conditions, such as temperature, reagent ratio, reaction time, etc., which will affect the yield and purity of the product. Only fine operation can achieve good synthesis results.
What are the physical properties of 3-nitro-4-chlorobenzenesulfonamide?
3 - nitro - 4 - chlorobenzenesulfonamide is an organic compound, and its physical properties are quite unique. Looking at its morphology, it is mostly white to light yellow crystalline powder under normal conditions. This is because its molecular structure is arranged in an orderly manner, resulting in its solid state.
When it comes to solubility, the compound has low solubility in water. This is because the molecule contains nitro, chlorine atoms and sulfonamide groups. Although sulfonamide groups have certain hydrophilicity, nitro and chlorine atoms have strong hydrophobicity. The combined action of the two makes it difficult to dissolve in water. However, in some organic solvents, such as dichloromethane, N, N - dimethylformamide (DMF), etc., it has good solubility. In dichloromethane, it can achieve better mutual dissolution by virtue of the van der Waals force and the principle of similar dissolution between the molecules of the compound; in DMF, in addition to the van der Waals force, the strong polarity of DMF and the formation of hydrogen bonds and other interactions of the compound enhance its solubility.
In terms of melting point, it has been determined that the melting point of 3-nitro-4-chlorobenzenesulfonamide is within a certain range, which is closely related to the intermolecular force. Interactions such as hydrogen bonds and van der Waals forces between molecules maintain the orderly arrangement of time-division molecules in the solid state, which requires a specific energy to break, so there is a corresponding melting point. When heated to the melting point temperature, the molecule obtains enough energy, and the lattice structure disintegrates, transforming from a solid state to a liquid state.
In addition, its density is also an important physical property. The compound has a relatively high density, which is due to the type and number of atoms in its molecular structure. The atoms contained in the benzene ring, nitro group, chlorine atom and sulfonamide group have relatively large masses, and the molecular arrangement is relatively close, resulting in an increase in mass per unit volume, resulting in a higher density.
In summary, the physical properties of 3-nitro-4-chlorobenzenesulfonamide, such as appearance, solubility, melting point and density, are determined by its unique molecular structure. These properties are of great significance in many fields such as organic synthesis and drug development.
When it comes to solubility, the compound has low solubility in water. This is because the molecule contains nitro, chlorine atoms and sulfonamide groups. Although sulfonamide groups have certain hydrophilicity, nitro and chlorine atoms have strong hydrophobicity. The combined action of the two makes it difficult to dissolve in water. However, in some organic solvents, such as dichloromethane, N, N - dimethylformamide (DMF), etc., it has good solubility. In dichloromethane, it can achieve better mutual dissolution by virtue of the van der Waals force and the principle of similar dissolution between the molecules of the compound; in DMF, in addition to the van der Waals force, the strong polarity of DMF and the formation of hydrogen bonds and other interactions of the compound enhance its solubility.
In terms of melting point, it has been determined that the melting point of 3-nitro-4-chlorobenzenesulfonamide is within a certain range, which is closely related to the intermolecular force. Interactions such as hydrogen bonds and van der Waals forces between molecules maintain the orderly arrangement of time-division molecules in the solid state, which requires a specific energy to break, so there is a corresponding melting point. When heated to the melting point temperature, the molecule obtains enough energy, and the lattice structure disintegrates, transforming from a solid state to a liquid state.
In addition, its density is also an important physical property. The compound has a relatively high density, which is due to the type and number of atoms in its molecular structure. The atoms contained in the benzene ring, nitro group, chlorine atom and sulfonamide group have relatively large masses, and the molecular arrangement is relatively close, resulting in an increase in mass per unit volume, resulting in a higher density.
In summary, the physical properties of 3-nitro-4-chlorobenzenesulfonamide, such as appearance, solubility, melting point and density, are determined by its unique molecular structure. These properties are of great significance in many fields such as organic synthesis and drug development.
What are 3-nitro-4-chlorobenzenesulfonamide safety precautions?
3-Nitro-4-chlorobenzenesulfonamide is also a chemical substance. When using this substance, all kinds of safety precautions must not be ignored.
Bear the brunt of toxicity. This substance may be toxic and can damage human health. When operating, it is necessary to take comprehensive protection. Wear protective clothing and strictly choose protective gloves to ensure that the hands are protected from damage; wear protective glasses to prevent substances from splashing into the eyes and hurting their eyes. And operate in a well-ventilated place, or in a fume hood, so that harmful gases can quickly disperse, do not stay, and endanger breathing.
Furthermore, the risk of explosion cannot be ignored. Although it is not an ordinary flammable material, it may encounter an open flame, hot topic, or the risk of ignition and explosion. Therefore, the storage place must be kept away from fire and heat sources, and should not be co-stored with strong oxidants to prevent their interaction and cause accidents.
Repeat, when using, precise operation is essential. Caution is required for weighing, transferring and other steps, so as not to scatter the material. If it is accidentally spilled, it should be cleaned up quickly according to the specifications to prevent pollution of the environment and endanger others.
When disposing of waste, it should not be ignored. It must be properly classified, stored and disposed of in accordance with the regulations of chemical waste disposal, and must not be discarded at will, so as not to pollute the soil, water sources and harm the ecology.
In short, when handling 3-nitro-4-chlorobenzenesulfonamide, safety must be the top priority and procedures must be followed to ensure safety.
Bear the brunt of toxicity. This substance may be toxic and can damage human health. When operating, it is necessary to take comprehensive protection. Wear protective clothing and strictly choose protective gloves to ensure that the hands are protected from damage; wear protective glasses to prevent substances from splashing into the eyes and hurting their eyes. And operate in a well-ventilated place, or in a fume hood, so that harmful gases can quickly disperse, do not stay, and endanger breathing.
Furthermore, the risk of explosion cannot be ignored. Although it is not an ordinary flammable material, it may encounter an open flame, hot topic, or the risk of ignition and explosion. Therefore, the storage place must be kept away from fire and heat sources, and should not be co-stored with strong oxidants to prevent their interaction and cause accidents.
Repeat, when using, precise operation is essential. Caution is required for weighing, transferring and other steps, so as not to scatter the material. If it is accidentally spilled, it should be cleaned up quickly according to the specifications to prevent pollution of the environment and endanger others.
When disposing of waste, it should not be ignored. It must be properly classified, stored and disposed of in accordance with the regulations of chemical waste disposal, and must not be discarded at will, so as not to pollute the soil, water sources and harm the ecology.
In short, when handling 3-nitro-4-chlorobenzenesulfonamide, safety must be the top priority and procedures must be followed to ensure safety.
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