3-Nitrochlorobenzene
Linshang Chemical
HS Code |
303792 |
Chemical Formula | C6H4ClNO2 |
Molar Mass | 157.55 g/mol |
Appearance | Yellow solid |
Odor | Characteristic odor |
Density | 1.348 g/cm³ |
Melting Point | 46 - 48 °C |
Boiling Point | 235 - 236 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in benzene, ether, ethanol |
Flash Point | 127 °C |
Vapor Pressure | Low vapor pressure |
Stability | Stable under normal conditions |
Hazard Class | Toxic |
As an accredited 3-Nitrochlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 25 - kg bags packaging for 3 - nitrochlorobenzene chemical. |
Storage | 3 - nitrochlorobenzene should be stored in a cool, well - ventilated warehouse. Keep it away from sources of ignition and heat. Store it separately from oxidizing agents, reducing agents, and alkalis to prevent chemical reactions. Use containers made of appropriate materials to avoid leakage, and ensure strict access control to prevent unauthorized handling. |
Shipping | 3 - nitrochlorobenzene is a hazardous chemical. It should be shipped in accordance with strict regulations, using specialized containers to prevent leakage. Documentation about its properties and safety measures must accompany the shipment. |
Competitive 3-Nitrochlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 3-Nitrochlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
This is an important intermediate in organic synthesis. In the field of drug synthesis, it is often a key raw material. Taking the preparation of β-blockers as an example, in the synthesis path of many β-blockers, 3-aminopropanol can undergo a series of chemical reactions to construct the key structure of drug molecules, which is of great significance for the development of drugs that regulate the function of the human cardiovascular system.
It also plays an important role in the preparation of surfactants. Because its molecular structure contains both amino and hydroxyl groups, it can react with different types of compounds to obtain surfactants with different properties. Such surfactants are widely used in the daily chemical, textile, petroleum and other industries, or are used to improve the emulsification properties of products, or enhance their dispersion effect, and help optimize the production process and product quality.
In the field of organic synthetic chemistry, 3-aminopropyl alcohol can participate in a variety of organic reactions, such as esterification and amidation, due to the active amino and hydroxyl groups it contains. With these reactions, many organic compounds with special structures and functions can be synthesized, providing a rich selection of raw materials for the research and development of organic synthetic chemistry, expanding the boundaries of synthetic chemistry, and creating more novel organic molecular structures to meet the needs of different fields for special performance organic compounds.
It is a colorless to pale yellow liquid at room temperature, with a faint special smell. Looking at its state, it is often presented in a liquid state, with good fluidity and agility like water.
When it comes to the melting point, it is about -43 ° C. At this temperature, 3-hydroxybutyric acid condenses from a liquid state to a solid state, like agile water turning into clear ice crystals. The boiling point is 207 ° C. When the temperature rises to this point, it will break free from the liquid state and rise into a gaseous state.
3-hydroxybutyric acid can be miscible with water in any ratio, which makes it quietly hidden in water and fuses with water. Not only that, it can also be dissolved in organic solvents such as ethanol and ether, showing good solubility, just like a walker who is good at adapting to different environments.
Its density is about 1.045g/cm ³, which is slightly heavier than water. If it is slowly injected into water, it will gradually sink like a stable thing.
In terms of optical properties, 3-hydroxybutyric acid has optical rotation, which means that it can change the vibration direction of polarized light, as if giving light a unique "rotating force". The physical properties of 3-hydroxybutyric acid determine its application possibilities in different fields. Whether it is in chemical production or biomedical research, it shows unique value due to these characteristics, just like a jade with infinite possibilities, waiting for the world to carve and explore.
Its molecule contains a conjugated system. Due to the indole ring, it has certain stability and special electron cloud distribution. This structure makes it exhibit unique activity in chemical reactions and has a special tendency to react to electrophilic reagents.
Furthermore, the carboxyl group of 3-carboxyl indolebutyric acid can participate in the esterification reaction. Under the catalysis of acid, it is dehydrated and condensed with alcohols to form ester compounds. This reaction is common in organic synthesis, which can increase its lipid solubility and expand its application domain.
In vivo, 3-carboxyindolebutyric acid is a plant growth regulator. Due to its specialization, it can interact with plant cell surface receptors and regulate plant growth and development through signal transduction pathways. Such as promoting rooting, controlling plant type, and regulating flowering and fruiting, etc., all depend on the compatibility of its chemical properties with plant physiological mechanisms. Its transportation and metabolism in plants are also related to its chemical properties, and play physiological functions in the form of prototypes or metabolites.
First, acetaldehyde is used as the base, through the method of condensation. First, under specific conditions, acetaldehyde is catalyzed by a base, and the reaction of hydroxybutyric aldehyde is carried out. Acetaldehyde interacts to produce 3-hydroxybutyric aldehyde. This reaction requires moderate temperature control and precise catalyst amount. Then, 3-hydroxybutyric aldehyde is oxidized with a suitable oxidant, such as silver ammonia solution or newly prepared copper hydroxide, etc., to obtain 3-hydroxybutyric acid. In this way, the raw material acetaldehyde is easy to obtain, but the reaction steps are slightly complicated, and the control of the reaction conditions is strict.
Second, ethyl acetoacetate is used as the starting material. First, ethyl acetoacetate is substituted with halogenated hydrocarbons in an alkaline environment, and the corresponding groups are introduced. After that, the steps of hydrolysis and decarboxylation. During hydrolysis, the ester group is converted into a carboxyl group catalyzed by acid or base. The decarboxylation process requires a suitable temperature and environment, and finally 3-hydroxybutyric acid can be prepared. There are many steps in this method, but the intermediate product is easier to separate and purify, which is conducive to obtaining a purer product.
Third, the method of biosynthesis. Some microorganisms, such as specific bacteria or fungi, can synthesize 3-hydroxybutyric acid through their own metabolic pathways using carbohydrates as raw materials in a suitable culture environment. This environment requires precise regulation of temperature, pH, nutrients, etc. The biosynthetic method is green and environmentally friendly, with good selectivity. However, the cultivation of microorganisms is time-consuming, and the yield may not meet the needs of large-scale production. It is often necessary to genetically engineer microorganisms to improve their synthetic ability.
At the environmental level, it has a certain water solubility. If it flows into the water body, it may cause toxicity to aquatic organisms. After aquatic organisms ingest or come into contact with this substance, their physiological functions may be disturbed, such as affecting the respiration and reproduction of fish. And in the water body, it may participate in a series of chemical reactions, change the chemical properties of the water body, and affect the ecological balance of the water body. If it enters the soil, or is adsorbed by soil particles, it affects the activity of soil microorganisms, interferes with material circulation and energy conversion in the soil, and may also inhibit the growth and development of plant roots, hindering plants from absorbing nutrients and water.
As far as the human body is concerned, 3-hydroxybutyraldehyde is irritating. If the skin is in contact, it may cause redness, itching, pain, and even cause symptoms such as contact dermatitis. When the eyes are in contact with it, the stimulation is more intense, which can cause severe eye pain, tears, redness and swelling, and in severe cases, vision may be damaged. If the volatile gas is accidentally inhaled, it will irritate the respiratory tract, causing symptoms such as cough, asthma, breathing difficulties, etc. Long-term inhalation, or cause continuous damage to the respiratory mucosa, increasing the chance of respiratory diseases. If taken by mistake, it will cause corrosive damage to the mouth, throat, gastrointestinal tract, etc., and cause nausea, vomiting, abdominal pain and other symptoms, which will endanger life and health in serious cases.
Therefore, for 3-hydroxybutyraldehyde, it needs to be properly disposed of and used to strictly prevent and control its harm to the environment and human body.

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