Linshang Chemical
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4-[2-(5-Chloro-2-Methoxy Benzamido) Ethyl] Benzene Sulfonamide
Linshang Chemical
|
HS Code |
583484 |
| Chemical Formula | C16H17ClN2O5S |
| Molecular Weight | 384.84 g/mol |
| Appearance | Solid (usually white to off - white powder) |
| Melting Point | Varies, typically in a certain temperature range (needs specific experimental data) |
| Solubility | Solubility characteristics vary by solvent, may be sparingly soluble in water, more soluble in some organic solvents |
| Pka | Relevant acid - base dissociation constant values (specific experimental data required) |
| Logp | Describes lipophilicity (experimental value needed) |
| Density | Experimental value required for accurate density data |
| Stability | Stability can be affected by factors like temperature, light, and humidity |
As an accredited 4-[2-(5-Chloro-2-Methoxy Benzamido) Ethyl] Benzene Sulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram vial of 4 - [2 - (5 - chloro - 2 - methoxy Benzamido) Ethyl] Benzene Sulfonamide. |
| Storage | Store 4-[2-(5 - chloro - 2 - methoxy benzamido)ethyl] benzene sulfonamide in a cool, dry place away from direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and contamination. Store it separately from incompatible substances, such as strong oxidizing agents and acids, to avoid potential chemical reactions. |
| Shipping | The chemical 4-[2-(5 - chloro - 2 - methoxy Benzamido)Ethyl]Benzene Sulfonamide is shipped in properly sealed containers. These are carefully packaged to prevent leakage, following strict regulations for chemical transportation. |
Competitive 4-[2-(5-Chloro-2-Methoxy Benzamido) Ethyl] Benzene Sulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
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Where to Buy 4-[2-(5-Chloro-2-Methoxy Benzamido) Ethyl] Benzene Sulfonamide in China?
As a trusted 4-[2-(5-Chloro-2-Methoxy Benzamido) Ethyl] Benzene Sulfonamide manufacturer, we deliver:
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As a leading 4-[2-(5-Chloro-2-Methoxy Benzamido) Ethyl] Benzene Sulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 4- [2- (5-chloro-2-methoxy Benzamido) Ethyl] Benzene Sulfonamide
This is to explore the chemical structure of 4- [2- (5-chloro-2-methoxybenzamido) ethyl] benzenesulfonamide. This compound has a unique structure and is cleverly combined by benzene ring, sulfonamido group, and benzamido group connected to ethyl group.
Looking at its main body, benzenesulfonamide is the base, and above the benzene ring, there are 4-position side chains with specific structures. In the side chain, 2-ethyl is connected to 5-chloro-2-methoxybenzamido group. In the 5-chloro-2-methoxybenzamide group, the 5-position on the benzene ring is a chlorine atom, and the 2-position is a methoxy group, and it is connected to the carbonyl and amino groups, and then connected to the ethyl group to form a complete side chain, which is connected to the 4-position of the benzene sulfonamide benzene ring.
This compound has a complex and delicate structure, and the interaction of various groups endows it with unique chemical and physical properties. The spatial arrangement and electronic effects of different substituents have a profound impact on its stability, solubility, reactivity and biological activity. Understanding this structure is the key to studying its chemical properties, pharmacological effects and potential applications, and also lays the foundation for further exploration in related fields.
Looking at its main body, benzenesulfonamide is the base, and above the benzene ring, there are 4-position side chains with specific structures. In the side chain, 2-ethyl is connected to 5-chloro-2-methoxybenzamido group. In the 5-chloro-2-methoxybenzamide group, the 5-position on the benzene ring is a chlorine atom, and the 2-position is a methoxy group, and it is connected to the carbonyl and amino groups, and then connected to the ethyl group to form a complete side chain, which is connected to the 4-position of the benzene sulfonamide benzene ring.
This compound has a complex and delicate structure, and the interaction of various groups endows it with unique chemical and physical properties. The spatial arrangement and electronic effects of different substituents have a profound impact on its stability, solubility, reactivity and biological activity. Understanding this structure is the key to studying its chemical properties, pharmacological effects and potential applications, and also lays the foundation for further exploration in related fields.
What are the main uses of 4- [2- (5-chloro-2-methoxy Benzamido) Ethyl] Benzene Sulfonamide
4- [2- (5-chloro-2-methoxybenzamido) ethyl] benzenesulfonamide, an organic compound. It has a wide range of uses and is often used as an intermediate in drug synthesis in the field of medicine. The genine structure contains specific functional groups, which can be combined with other compounds through chemical reactions to generate drug molecules with specific pharmacological activities.
In the process of drug development, scientists use it to construct complex drug structures and explore new therapeutic drugs. For example, by modifying its structure, compounds with high affinity and selectivity for specific disease targets can be obtained, providing a key foundation for the development of new drugs for the treatment of cancer, cardiovascular diseases and other difficult diseases.
In addition, in the chemical industry, or for the synthesis of special functional materials. Due to its unique physical and chemical properties, or can participate in the preparation of materials with specific adsorption and separation properties, used in the purification and separation process of chemical products, improve product quality and production efficiency.
Because it contains functional groups such as chlorine and methoxy, or affects the stability and solubility of materials, it is also an important research object in materials science research. It helps researchers develop functional materials with novel properties to meet different industrial and scientific research needs.
In the process of drug development, scientists use it to construct complex drug structures and explore new therapeutic drugs. For example, by modifying its structure, compounds with high affinity and selectivity for specific disease targets can be obtained, providing a key foundation for the development of new drugs for the treatment of cancer, cardiovascular diseases and other difficult diseases.
In addition, in the chemical industry, or for the synthesis of special functional materials. Due to its unique physical and chemical properties, or can participate in the preparation of materials with specific adsorption and separation properties, used in the purification and separation process of chemical products, improve product quality and production efficiency.
Because it contains functional groups such as chlorine and methoxy, or affects the stability and solubility of materials, it is also an important research object in materials science research. It helps researchers develop functional materials with novel properties to meet different industrial and scientific research needs.
What is the synthesis method of 4- [2- (5-chloro-2-methoxy Benzamido) Ethyl] Benzene Sulfonamide
To prepare 4- [2- (5-chloro-2-methoxybenzamido) ethyl] benzenesulfonamide, the following method can be followed.
First take 5-chloro-2-methoxybenzoic acid and react it with appropriate reagents to activate the carboxyl group. The common ones are treated with thionyl chloride to obtain 5-chloro-2-methoxybenzoyl chloride. This step requires a suitable solvent, such as dichloromethane, etc., at a mild temperature, such as near room temperature, when stirring the reaction number, until the reaction is complete, to obtain this acid chloride product.
Take 2-aminoethylbenzenesulfonamide and react it with 5-chloro-2-methoxybenzoyl chloride obtained above. Using triethylamine and other organic bases as acid binding agents, in dichloromethane or N, N-dimethylformamide and other solvents, the reaction starts at a low temperature such as about 0 ° C, and then gradually rises to room temperature, stirring for a few times. This reaction is a nucleophilic substitution. The amino group attacks the carbonyl carbon of the acyl chloride to form an amide bond. After post-treatment, such as washing with dilute acid or dilute base, and then column chromatography or recrystallization, 4 - [2- (5-chloro-2-methoxybenzamido) ethyl] benzenesulfonamide can be obtained.
Or the amino group of 2-aminoethylbenzenesulfonamide can be protected first, such as with a protective group such as tert-butoxycarbonyl, and then reacted with 5-chloro-2-methoxybenzoyl chloride. After the reaction is completed, the protective group is removed to obtain the target product. The conditions for removing protective groups vary depending on the protective groups used. For example, tert-butoxycarbonyl can be removed by dilute acid treatment. This whole process requires attention to the control of reaction conditions, the selection of solvents, the dosage ratio of reagents, and the fine operation of post-processing to obtain products with higher yield and purity.
First take 5-chloro-2-methoxybenzoic acid and react it with appropriate reagents to activate the carboxyl group. The common ones are treated with thionyl chloride to obtain 5-chloro-2-methoxybenzoyl chloride. This step requires a suitable solvent, such as dichloromethane, etc., at a mild temperature, such as near room temperature, when stirring the reaction number, until the reaction is complete, to obtain this acid chloride product.
Take 2-aminoethylbenzenesulfonamide and react it with 5-chloro-2-methoxybenzoyl chloride obtained above. Using triethylamine and other organic bases as acid binding agents, in dichloromethane or N, N-dimethylformamide and other solvents, the reaction starts at a low temperature such as about 0 ° C, and then gradually rises to room temperature, stirring for a few times. This reaction is a nucleophilic substitution. The amino group attacks the carbonyl carbon of the acyl chloride to form an amide bond. After post-treatment, such as washing with dilute acid or dilute base, and then column chromatography or recrystallization, 4 - [2- (5-chloro-2-methoxybenzamido) ethyl] benzenesulfonamide can be obtained.
Or the amino group of 2-aminoethylbenzenesulfonamide can be protected first, such as with a protective group such as tert-butoxycarbonyl, and then reacted with 5-chloro-2-methoxybenzoyl chloride. After the reaction is completed, the protective group is removed to obtain the target product. The conditions for removing protective groups vary depending on the protective groups used. For example, tert-butoxycarbonyl can be removed by dilute acid treatment. This whole process requires attention to the control of reaction conditions, the selection of solvents, the dosage ratio of reagents, and the fine operation of post-processing to obtain products with higher yield and purity.
What are the safety and toxicity of 4- [2- (5-chloro-2-methoxy Benzamido) Ethyl] Benzene Sulfonamide
4- [2- (5-chloro-2-methoxybenzamido) ethyl] benzenesulfonamide, its safety and toxicity are related to human health and cannot be ignored.
Looking at its chemical structure, it contains chlorine, methoxy, benzamido and benzenesulfonamido groups. The introduction of chlorine atoms may change the polarity and chemical reactivity of molecules, affecting their metabolism in organisms and their interaction with biological macromolecules. Methoxy groups can increase molecular fat solubility, or promote its penetration through biological membranes, which in turn affects distribution and toxicity.
In terms of safety, when synthesizing and using, it is necessary to control the conditions to avoid the formation of impurities. Impurities may have higher toxicity, threatening the safety of operators and the environment. And the preparation, storage and transportation should be in accordance with regulations to prevent leakage and diffusion.
Regarding its toxicity, although there is no detailed ancient book to study, it is inferred from today's chemical principles and similar compounds, or there is potential harm. Or irritate the skin, eyes and respiratory tract, interfere with normal physiological functions due to active groups, or combine with macromolecules such as proteins and nucleic acids in organisms. Long-term exposure may involve carcinogenic, teratogenic, and mutagenic risks, but all of these need to be confirmed by experiments.
And because of its benzene ring structure, some benzene series compounds are neurotoxic and blood toxic, and this substance may also have similar risks. Therefore, when using research, it is necessary to strictly abide by safety procedures, use protective equipment to ensure the safety of personnel, and properly dispose of waste to protect the ecological environment.
Looking at its chemical structure, it contains chlorine, methoxy, benzamido and benzenesulfonamido groups. The introduction of chlorine atoms may change the polarity and chemical reactivity of molecules, affecting their metabolism in organisms and their interaction with biological macromolecules. Methoxy groups can increase molecular fat solubility, or promote its penetration through biological membranes, which in turn affects distribution and toxicity.
In terms of safety, when synthesizing and using, it is necessary to control the conditions to avoid the formation of impurities. Impurities may have higher toxicity, threatening the safety of operators and the environment. And the preparation, storage and transportation should be in accordance with regulations to prevent leakage and diffusion.
Regarding its toxicity, although there is no detailed ancient book to study, it is inferred from today's chemical principles and similar compounds, or there is potential harm. Or irritate the skin, eyes and respiratory tract, interfere with normal physiological functions due to active groups, or combine with macromolecules such as proteins and nucleic acids in organisms. Long-term exposure may involve carcinogenic, teratogenic, and mutagenic risks, but all of these need to be confirmed by experiments.
And because of its benzene ring structure, some benzene series compounds are neurotoxic and blood toxic, and this substance may also have similar risks. Therefore, when using research, it is necessary to strictly abide by safety procedures, use protective equipment to ensure the safety of personnel, and properly dispose of waste to protect the ecological environment.
How competitive is 4- [2- (5-chloro-2-methoxy Benzamido) Ethyl] Benzene Sulfonamide in the market?
There are currently chemicals 4- [2- (5-chloro-2-methoxybenzamido) ethyl] benzenesulfonamide, and we would like to know how competitive it is in the market. This is an important consideration in the field of fine chemicals.
If the synthetic process of similar products in Guanfu is unique and efficient, the cost is controlled, the price is affordable and the quality is excellent, this is a benefit. If the research and development work is deep, and it has outstanding performance in specific application scenarios, such as the targeted effect on specific diseases in the field of medicine, or the material field can endow the material with special properties, the competitiveness is strong.
Furthermore, marketing activities and channels are also key. If the marketing is effective, well-known and trusted by users, widely distributed, and can occupy a place in the market.
However, looking at this 4- [2- (5-chloro-2-methoxybenzamido) ethyl] benzenesulfonamide, if its synthesis requires a difficult process, resulting in high cost, high price and low cost performance, or application performance without significant advantages and lack of strong promotion, it may be weak in the market. On the contrary, if the craftsmanship is advanced, the performance is excellent, and the promotion is effective, it can win a favorable position in the market, generate great profits for the merchants, and add brilliance to the industry.
If the synthetic process of similar products in Guanfu is unique and efficient, the cost is controlled, the price is affordable and the quality is excellent, this is a benefit. If the research and development work is deep, and it has outstanding performance in specific application scenarios, such as the targeted effect on specific diseases in the field of medicine, or the material field can endow the material with special properties, the competitiveness is strong.
Furthermore, marketing activities and channels are also key. If the marketing is effective, well-known and trusted by users, widely distributed, and can occupy a place in the market.
However, looking at this 4- [2- (5-chloro-2-methoxybenzamido) ethyl] benzenesulfonamide, if its synthesis requires a difficult process, resulting in high cost, high price and low cost performance, or application performance without significant advantages and lack of strong promotion, it may be weak in the market. On the contrary, if the craftsmanship is advanced, the performance is excellent, and the promotion is effective, it can win a favorable position in the market, generate great profits for the merchants, and add brilliance to the industry.
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