Linshang Chemical
PRODUCTS
4-(2-Methoxy-5-Chlorobenzamidoethyl)Benzenesulfonamide
Linshang Chemical
|
HS Code |
319878 |
| Chemical Formula | C16H17ClN2O4S |
| Molar Mass | 368.84 g/mol |
As an accredited 4-(2-Methoxy-5-Chlorobenzamidoethyl)Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram pack of 4-(2 - methoxy - 5 - chlorobenzamidoethyl)benzenesulfonamide in sealed container. |
| Storage | Store 4-(2 - methoxy - 5 - chlorobenzamidoethyl)benzenesulfonamide in a cool, dry place, away from direct sunlight and heat sources. Keep it in a well - sealed container to prevent moisture absorption and contamination. Store separately from incompatible substances to avoid potential chemical reactions. |
| Shipping | 4-(2 - methoxy - 5 - chlorobenzamidoethyl)benzenesulfonamide is shipped in accordance with strict chemical transport regulations. Packaged securely in suitable containers to prevent leakage, transported via approved carriers ensuring safety during transit. |
Competitive 4-(2-Methoxy-5-Chlorobenzamidoethyl)Benzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-(2-Methoxy-5-Chlorobenzamidoethyl)Benzenesulfonamide in China?
As a trusted 4-(2-Methoxy-5-Chlorobenzamidoethyl)Benzenesulfonamide manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-(2-Methoxy-5-Chlorobenzamidoethyl)Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 4- (2-methoxy-5-chlorobenzamidethyl) benzenesulfonamide?
The chemical structure of 4- (2-methoxy-5-chlorobenzoyl ethyl) benzoyl chloride is a subject that needs to be studied in detail in the field of organic chemistry. In this structure, the benzene ring is the key skeleton, and the groups connected to it give it unique chemical properties.
The first part of benzoyl chloride, which is a group with active chemical properties, the presence of chlorine atoms makes it highly active in nucleophilic substitution and other reactions. The benzene ring connected to it, as an electron delocalization system, affects the reactivity of benzoyl chloride groups, and the interaction between the two determines the basic chemical behavior of this compound.
Looking at the part of 2-methoxy-5-chlorobenzoyl ethyl, the methoxy group has a donor electron effect, which can affect the density distribution of the electron cloud of the benzene ring, making the specific position of the benzene ring more prone to electrophilic substitution; the chlorine atom has both electron-absorbing induction effect and electron-donor conjugation effect, which also has a significant effect on the electron cloud of the benzene ring. The substitution of the two at a specific position of the benzene ring determines the spatial structure and electronic properties of this part.
Ethyl group is used as a connecting group to connect 2-methoxy-5-chlorobenzoyl group with benzoyl chloride, which not only affects the overall spatial conformation of the molecule, but also has a certain impact on the intermolecular interaction Its flexible structure allows molecules to exist in various forms in space, which in turn affects their physical and chemical properties.
In summary, the chemical structure of 4- (2-methoxy-5-chlorobenzoyl ethyl) benzoyl chloride is composed of benzene ring, benzoyl chloride group, methoxy group, chlorine atom and ethyl group. Each part interacts to determine the unique chemical properties and reactivity of this compound, which is of great significance in organic synthesis and related fields.
The first part of benzoyl chloride, which is a group with active chemical properties, the presence of chlorine atoms makes it highly active in nucleophilic substitution and other reactions. The benzene ring connected to it, as an electron delocalization system, affects the reactivity of benzoyl chloride groups, and the interaction between the two determines the basic chemical behavior of this compound.
Looking at the part of 2-methoxy-5-chlorobenzoyl ethyl, the methoxy group has a donor electron effect, which can affect the density distribution of the electron cloud of the benzene ring, making the specific position of the benzene ring more prone to electrophilic substitution; the chlorine atom has both electron-absorbing induction effect and electron-donor conjugation effect, which also has a significant effect on the electron cloud of the benzene ring. The substitution of the two at a specific position of the benzene ring determines the spatial structure and electronic properties of this part.
Ethyl group is used as a connecting group to connect 2-methoxy-5-chlorobenzoyl group with benzoyl chloride, which not only affects the overall spatial conformation of the molecule, but also has a certain impact on the intermolecular interaction Its flexible structure allows molecules to exist in various forms in space, which in turn affects their physical and chemical properties.
In summary, the chemical structure of 4- (2-methoxy-5-chlorobenzoyl ethyl) benzoyl chloride is composed of benzene ring, benzoyl chloride group, methoxy group, chlorine atom and ethyl group. Each part interacts to determine the unique chemical properties and reactivity of this compound, which is of great significance in organic synthesis and related fields.
What are the main uses of 4- (2-methoxy-5-chlorobenzamidethyl) benzenesulfonamide?
4- (2-methoxy-5-chlorobenzoxyethoxy) ethyl benzoate, which is an important intermediate in the field of organic synthesis. Its main uses are many, and in the field of medicinal chemistry, it can be used as a key raw material for the preparation of a variety of drugs with specific physiological activities. For example, in the process of developing innovative drugs for specific disease targets, the substance can use its unique chemical structure to build the core skeleton of drug molecules through a series of chemical reactions, helping to achieve precise treatment of diseases.
In the field of materials science, it also has extraordinary performance. Due to its special functional groups, it can participate in the synthesis of polymer materials. Through a well-designed polymerization reaction, it can be integrated into the structure of a polymer, giving the material unique properties such as good solubility, thermal stability or specific optical properties, laying the foundation for the development of new functional materials.
In the fine chemical industry, it is widely used in the preparation of fine chemicals such as fragrances and cosmetic additives. Due to its chemical structure, it can be derived from unique aromas or special functional ingredients such as skin care and hair care, so it can improve product quality and added value, and meet consumers' demand for high-quality fine chemical products. With its diverse and important uses, this substance plays an indispensable role in many fields.
In the field of materials science, it also has extraordinary performance. Due to its special functional groups, it can participate in the synthesis of polymer materials. Through a well-designed polymerization reaction, it can be integrated into the structure of a polymer, giving the material unique properties such as good solubility, thermal stability or specific optical properties, laying the foundation for the development of new functional materials.
In the fine chemical industry, it is widely used in the preparation of fine chemicals such as fragrances and cosmetic additives. Due to its chemical structure, it can be derived from unique aromas or special functional ingredients such as skin care and hair care, so it can improve product quality and added value, and meet consumers' demand for high-quality fine chemical products. With its diverse and important uses, this substance plays an indispensable role in many fields.
How safe is 4- (2-methoxy-5-chlorobenzamidethyl) benzenesulfonamide?
4- (2-Amino-5-bromobenzoethyl) benzoylaniline, the safety of this compound is quite complex and needs to be reviewed in detail from many aspects.
First, its chemical structure, 2-amino and 5-bromine substituents give it specific reactivity. Amino is nucleophilic, and it is easy to react with electrophilic reagents under certain conditions, or cause chemical changes, resulting in unknown products, which affects its safety. Although bromine atoms are relatively stable, they may undergo debromination reactions in specific environments, such as strong reducing agents or high temperatures, changing molecular structures and properties.
From a toxicity point of view, organic compounds containing benzene ring structure often have potential toxicity risks. Benzene ring is easily metabolized and transformed in living organisms to form reactive intermediates, which may covalently bind with biological macromolecules such as DNA and proteins, interfere with normal physiological functions, cause cell damage, mutation, long-term exposure or increase the risk of cancer. This compound contains multiple benzoyl groups, which may increase the lipid solubility, making it easy to pass through the biofilm and accumulate in the body, increasing the potential harm to organs and tissues.
In terms of environmental impact, if this compound enters the environment, its complex structure or degradation is difficult. Residual in natural water and soil for a long time may affect the ecosystem. When brominated organic matter degrades in the environment or generates products such as bromine ions, it is toxic to soil microbial communities and water organisms, and destroys ecological balance.
In the process of industrial production and use, the synthesis process may require the use of toxic and harmful raw materials and solvents. If the reaction conditions are not properly controlled, or the raw materials and intermediates are leaked, which threatens the health of operators and the safety of the surrounding environment. And the waste generated in the production process, if not properly handled, will also cause pollution to the environment.
First, its chemical structure, 2-amino and 5-bromine substituents give it specific reactivity. Amino is nucleophilic, and it is easy to react with electrophilic reagents under certain conditions, or cause chemical changes, resulting in unknown products, which affects its safety. Although bromine atoms are relatively stable, they may undergo debromination reactions in specific environments, such as strong reducing agents or high temperatures, changing molecular structures and properties.
From a toxicity point of view, organic compounds containing benzene ring structure often have potential toxicity risks. Benzene ring is easily metabolized and transformed in living organisms to form reactive intermediates, which may covalently bind with biological macromolecules such as DNA and proteins, interfere with normal physiological functions, cause cell damage, mutation, long-term exposure or increase the risk of cancer. This compound contains multiple benzoyl groups, which may increase the lipid solubility, making it easy to pass through the biofilm and accumulate in the body, increasing the potential harm to organs and tissues.
In terms of environmental impact, if this compound enters the environment, its complex structure or degradation is difficult. Residual in natural water and soil for a long time may affect the ecosystem. When brominated organic matter degrades in the environment or generates products such as bromine ions, it is toxic to soil microbial communities and water organisms, and destroys ecological balance.
In the process of industrial production and use, the synthesis process may require the use of toxic and harmful raw materials and solvents. If the reaction conditions are not properly controlled, or the raw materials and intermediates are leaked, which threatens the health of operators and the safety of the surrounding environment. And the waste generated in the production process, if not properly handled, will also cause pollution to the environment.
What are the synthesis methods of 4- (2-methoxy-5-chlorobenzamidethyl) benzenesulfonamide?
To prepare 4- (2-methoxy-5-bromobenzyloxy) benzyl bromide, the following methods can be adopted:
First, start with 2-methoxy-5-bromobenzyl alcohol, and first react it with p-toluenesulfonyl chloride in the environment of pyridine and other bases to obtain 2-methoxy-5-bromobenzyl p-toluenesulfonate. This ester is very active, and then reacts with sodium bromide in an appropriate solvent (such as N, N-dimethylformamide). After nucleophilic substitution, 4- (2-methoxy-5-bromobenzyloxy) benzyl bromide is obtained. This path step is relatively clear, the reaction conditions of each step are relatively mild, and the yield is considerable. The reaction principle is that the alcohol is first converted into a more active sulfonate, which is convenient for the nucleophilic substitution of bromine ions.
Second, 4-hydroxybenzyl bromide and 2-methoxy-5-bromobenzyl bromide are used as raw materials. Under alkaline conditions such as potassium carbonate, in solvents such as acetonitrile, the nucleophilic substitution reaction occurs between the two. The hydroxyl oxygen of 4-hydroxybenzyl bromide is nucleophilic, attacking the benzyl carbon of 2-methoxy-5-bromobenzyl bromide, and the bromine ion leaves to obtain the target product. The raw materials of this method are relatively easy to obtain, and the reaction operation is not cumbersome. The key is to control the amount of base and the reaction temperature to ensure the smooth progress of the reaction and avoid side reactions, such as the self-polymerization of 4-hydroxybenzyl bromide.
Third, 4-hydroxybenzyl alcohol can be protected first. For example, the hydroxyl group is protected with tert-butyl dimethylsilyl chloride to obtain 4- (tert-butyl dimethylsiloxy) benzyl alcohol. Then react with hydrobromic acid to convert the benzyl hydroxyl group into a bromine atom to obtain 4- (tert-butyl dimethylsiloxy) benzyl bromide. Finally, deprotect with 2-methoxy-5-bromobenzyl alcohol under the action of tetrabutylammonium fluoride and undergo a substitution reaction to obtain 4- (2-methoxy-5-bromobenzyl) benzyl bromide. Although this approach has a little more steps, it has better selectivity control for the reaction and is suitable for situations where high product purity is required.
First, start with 2-methoxy-5-bromobenzyl alcohol, and first react it with p-toluenesulfonyl chloride in the environment of pyridine and other bases to obtain 2-methoxy-5-bromobenzyl p-toluenesulfonate. This ester is very active, and then reacts with sodium bromide in an appropriate solvent (such as N, N-dimethylformamide). After nucleophilic substitution, 4- (2-methoxy-5-bromobenzyloxy) benzyl bromide is obtained. This path step is relatively clear, the reaction conditions of each step are relatively mild, and the yield is considerable. The reaction principle is that the alcohol is first converted into a more active sulfonate, which is convenient for the nucleophilic substitution of bromine ions.
Second, 4-hydroxybenzyl bromide and 2-methoxy-5-bromobenzyl bromide are used as raw materials. Under alkaline conditions such as potassium carbonate, in solvents such as acetonitrile, the nucleophilic substitution reaction occurs between the two. The hydroxyl oxygen of 4-hydroxybenzyl bromide is nucleophilic, attacking the benzyl carbon of 2-methoxy-5-bromobenzyl bromide, and the bromine ion leaves to obtain the target product. The raw materials of this method are relatively easy to obtain, and the reaction operation is not cumbersome. The key is to control the amount of base and the reaction temperature to ensure the smooth progress of the reaction and avoid side reactions, such as the self-polymerization of 4-hydroxybenzyl bromide.
Third, 4-hydroxybenzyl alcohol can be protected first. For example, the hydroxyl group is protected with tert-butyl dimethylsilyl chloride to obtain 4- (tert-butyl dimethylsiloxy) benzyl alcohol. Then react with hydrobromic acid to convert the benzyl hydroxyl group into a bromine atom to obtain 4- (tert-butyl dimethylsiloxy) benzyl bromide. Finally, deprotect with 2-methoxy-5-bromobenzyl alcohol under the action of tetrabutylammonium fluoride and undergo a substitution reaction to obtain 4- (2-methoxy-5-bromobenzyl) benzyl bromide. Although this approach has a little more steps, it has better selectivity control for the reaction and is suitable for situations where high product purity is required.
What is the market prospect of 4- (2-methoxy-5-chlorobenzamidethyl) benzenesulfonamide?
The market prospect of 4- (2-amino-5-bromobenzyloxy ethyl) benzoic acid involves many factors and is a complex matter.
Looking at this compound, it may have potential applications in the field of medicine. Nowadays, the pharmaceutical industry is developing rapidly, and the demand for new compounds is increasing. If this substance is confirmed to have specific pharmacological activities, such as antibacterial, anti-inflammatory or anti-tumor effects, and can be converted into safe and effective drugs through subsequent research and development, it will surely find a place in the pharmaceutical market. The pharmaceutical market is huge. Once a new drug is approved for marketing, if the efficacy is significant, it can often obtain high returns, and its prospects are bright.
In the field of materials science, there may be a place for it. With the progress of science and technology, the demand for functional materials is increasing. If this compound has unique physical and chemical properties, such as good thermal stability, optical properties or electrical properties, it may be used to prepare new polymer materials, optical materials, etc. The material market is widely used, from electronic equipment to aerospace, if it can meet the specific material needs, the market prospect is also broad.
However, its market prospect also faces challenges. The complexity and cost of the synthesis process are crucial. If the synthesis process is cumbersome and costly, large-scale production and marketing activities will be limited. And there are strict regulations and standards in the fields of medicine and materials. In order to enter the market, this compound needs to meet the relevant quality and safety requirements, the R & D cycle may be extended, and the cost will also increase.
In summary, although 4- (2-amino-5-bromobenzyloxy ethyl) benzoic acid has an addressable market opportunity, in order to achieve a good market prospect, many obstacles such as synthesis and regulations need to be overcome. After in-depth research and development, it is expected to shine in the pharmaceutical or materials market.
Looking at this compound, it may have potential applications in the field of medicine. Nowadays, the pharmaceutical industry is developing rapidly, and the demand for new compounds is increasing. If this substance is confirmed to have specific pharmacological activities, such as antibacterial, anti-inflammatory or anti-tumor effects, and can be converted into safe and effective drugs through subsequent research and development, it will surely find a place in the pharmaceutical market. The pharmaceutical market is huge. Once a new drug is approved for marketing, if the efficacy is significant, it can often obtain high returns, and its prospects are bright.
In the field of materials science, there may be a place for it. With the progress of science and technology, the demand for functional materials is increasing. If this compound has unique physical and chemical properties, such as good thermal stability, optical properties or electrical properties, it may be used to prepare new polymer materials, optical materials, etc. The material market is widely used, from electronic equipment to aerospace, if it can meet the specific material needs, the market prospect is also broad.
However, its market prospect also faces challenges. The complexity and cost of the synthesis process are crucial. If the synthesis process is cumbersome and costly, large-scale production and marketing activities will be limited. And there are strict regulations and standards in the fields of medicine and materials. In order to enter the market, this compound needs to meet the relevant quality and safety requirements, the R & D cycle may be extended, and the cost will also increase.
In summary, although 4- (2-amino-5-bromobenzyloxy ethyl) benzoic acid has an addressable market opportunity, in order to achieve a good market prospect, many obstacles such as synthesis and regulations need to be overcome. After in-depth research and development, it is expected to shine in the pharmaceutical or materials market.
Scan to WhatsApp
