Linshang Chemical
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4-(4-Chlorophenoxy)Iodobenzene
Linshang Chemical
|
HS Code |
813880 |
| Chemical Formula | C6H4IClO |
| Molecular Weight | 268.45 |
| Appearance | Solid |
| Color | Off - white to light yellow |
| Melting Point | 122 - 124 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Purity | Typically high - purity grades available, e.g., 95%+ |
As an accredited 4-(4-Chlorophenoxy)Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 4-(4 - chlorophenoxy)iodobenzene packaged in a sealed glass bottle. |
| Storage | 4-(4 - Chlorophenoxy)iodobenzene should be stored in a cool, dry place away from direct sunlight. Keep it in a well - ventilated area, isolated from incompatible substances like strong oxidizing agents. Store in a tightly sealed container to prevent exposure to moisture and air, which could potentially lead to degradation of this chemical. |
| Shipping | 4-(4 - chlorophenoxy)iodobenzene is shipped in well - sealed containers, often within temperature - controlled environments. Special care is taken to prevent breakage, as it's a chemical, and shipping adheres to strict hazardous material regulations. |
Competitive 4-(4-Chlorophenoxy)Iodobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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As a leading 4-(4-Chlorophenoxy)Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 4- (4-chlorophenoxy) iodobenzene?
4- (4 'chlorophenoxy) iodobenzene is also an organic compound. The analysis of its chemical structure is very important for chemical research and organic synthesis.
The structure of this compound is based on the phenyl ring. The para-position of a phenyl ring, which is connected to an iodine atom, iodine, and a halogen element, also have specific chemical activities, which affect the reactivity of molecules. In reactions such as nucleophilic substitution, it is often a leaving group, introducing other groups into the molecular structure.
The para-position of another phenyl ring is connected to a 4-chlorophenoxy group. In this case, the phenoxy group is an aromatic ether group with an oxygen atom, and the oxygen atom is connected to the benzene ring by a single bond, and is connected to the para-position of the other phenyl ring. The chlorine atom in the 4-chlorophenoxy group, also a halogen element, can affect the electron cloud density of the benzene ring on the benzene ring, causing the change of the electrophilic substitution reaction activity of the benzene ring.
The two benzene rings are connected by oxygen atoms as a bridge to form this compound. Overall, 4- (4-chlorophenoxy) iodobenzene has a unique structure. The benzene ring, iodine atom, chlorine atom and oxygen atom coexist in one molecule. Each group interacts to give the molecule specific physical and chemical properties. In the field of organic synthesis, it is often a key intermediate, participating in a variety of organic reactions to prepare more complex and fine organic compounds.
The structure of this compound is based on the phenyl ring. The para-position of a phenyl ring, which is connected to an iodine atom, iodine, and a halogen element, also have specific chemical activities, which affect the reactivity of molecules. In reactions such as nucleophilic substitution, it is often a leaving group, introducing other groups into the molecular structure.
The para-position of another phenyl ring is connected to a 4-chlorophenoxy group. In this case, the phenoxy group is an aromatic ether group with an oxygen atom, and the oxygen atom is connected to the benzene ring by a single bond, and is connected to the para-position of the other phenyl ring. The chlorine atom in the 4-chlorophenoxy group, also a halogen element, can affect the electron cloud density of the benzene ring on the benzene ring, causing the change of the electrophilic substitution reaction activity of the benzene ring.
The two benzene rings are connected by oxygen atoms as a bridge to form this compound. Overall, 4- (4-chlorophenoxy) iodobenzene has a unique structure. The benzene ring, iodine atom, chlorine atom and oxygen atom coexist in one molecule. Each group interacts to give the molecule specific physical and chemical properties. In the field of organic synthesis, it is often a key intermediate, participating in a variety of organic reactions to prepare more complex and fine organic compounds.
What are the main physical properties of 4- (4-chlorophenoxy) iodobenzene?
4- (4-chlorophenoxy) iodobenzene is a kind of organic compound. Its physical properties are quite important, and it is related to the application and characteristics of this compound.
First of all, its appearance is often white to light yellow crystalline powder. This color state is easy to visually distinguish. In experiments and industrial operations, its purity and state can be preliminarily judged by its appearance.
When it comes to melting point, 4- (4-chlorophenoxy) iodobenzene has a specific melting point value. Determination of melting point is an important means to identify this compound. Accurate knowledge of melting point can help confirm its purity, and the melting point is often changed due to the mixing of impurities.
The other is solubility. In organic solvents, such as common ethanol and dichloromethane, 4- (4-chlorophenoxy) iodobenzene exhibits a certain solubility. This property makes it able to dissolve in organic synthesis reactions with suitable solvents, participate in various chemical reactions, and achieve the desired synthesis goals.
Density is also one of its physical properties. The exact density value is of great significance to the measurement of materials in chemical production and experimental operations. It is related to the accuracy of the reaction ratio, which in turn affects the quality and yield of the product.
In addition, its stability cannot be ignored during storage and use. Under normal conditions, 4- (4-chlorophenoxy) iodobenzene is relatively stable, and may change in case of strong light, hot topics or specific chemicals. Therefore, environmental factors should be paid attention to when storing to ensure its stability.
In short, the physical properties of 4- (4-chlorophenoxy) iodobenzene play a key role in organic synthesis, chemical production and other fields. Practitioners must understand in detail before they can make good use of this compound.
First of all, its appearance is often white to light yellow crystalline powder. This color state is easy to visually distinguish. In experiments and industrial operations, its purity and state can be preliminarily judged by its appearance.
When it comes to melting point, 4- (4-chlorophenoxy) iodobenzene has a specific melting point value. Determination of melting point is an important means to identify this compound. Accurate knowledge of melting point can help confirm its purity, and the melting point is often changed due to the mixing of impurities.
The other is solubility. In organic solvents, such as common ethanol and dichloromethane, 4- (4-chlorophenoxy) iodobenzene exhibits a certain solubility. This property makes it able to dissolve in organic synthesis reactions with suitable solvents, participate in various chemical reactions, and achieve the desired synthesis goals.
Density is also one of its physical properties. The exact density value is of great significance to the measurement of materials in chemical production and experimental operations. It is related to the accuracy of the reaction ratio, which in turn affects the quality and yield of the product.
In addition, its stability cannot be ignored during storage and use. Under normal conditions, 4- (4-chlorophenoxy) iodobenzene is relatively stable, and may change in case of strong light, hot topics or specific chemicals. Therefore, environmental factors should be paid attention to when storing to ensure its stability.
In short, the physical properties of 4- (4-chlorophenoxy) iodobenzene play a key role in organic synthesis, chemical production and other fields. Practitioners must understand in detail before they can make good use of this compound.
What are the common synthesis methods of 4- (4-chlorophenoxy) iodobenzene?
4- (4 -chlorophenoxy) iodobenzene is a common compound in organic synthesis. The synthesis method has been explored in the past, and several common methods are described in detail today.
First, the method of nucleophilic substitution reaction. Using 4-chlorophenol and iodobenzene derivatives as raw materials, in the presence of alkali, the nucleophilic substitution reaction can occur between the two. Base can promote the deprotonation of 4-chlorophenol phenol hydroxyl group, enhance its nucleophilicity, and then replace the carbon connected to the iodine atom in the iodobenzene derivative to generate 4- (4-chlorophenoxy) iodobenzene. Commonly used bases include potassium carbonate, sodium carbonate, etc. The reaction solvents are mostly N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO) and other aprotonic polar solvents. Such solvents can dissolve raw materials and bases and promote the reaction.
Second, the method of transition metal catalysis. Transition metals such as palladium and copper are used as catalysts to couple 4-chlorophenol with iodobenzene. In palladium catalysis, ligands are often required, such as triphenylphosphine, which can adjust the electron cloud density and spatial structure of palladium catalysts, improve catalytic activity and selectivity. The reaction system also requires the participation of alkali, which can not only promote the activation of phenolic hydroxyl groups, but also adjust the pH of the reaction, which is conducive to the reaction. The method of copper catalysis also has its own unique characteristics. The catalyst price is relatively low, and the reaction conditions may be milder, which can reduce the synthesis cost to a certain extent.
Third, through the method of functional group conversion. First, the functional group of iodobenzene is modified, and groups that are easy to react with 4-chlorophenol are introduced, such as halogen atoms, sulfonate ester groups, etc. After that, the modified iodobenzene derivative is reacted with 4-chlorophenol under suitable conditions. After substitution and other steps, 4- (4-chlorophenoxy) iodobenzene can also be obtained. In this process, the control of the reaction conditions is very critical. According to the characteristics of the introduced functional groups, the appropriate reaction reagents, reaction temperature, time and other conditions should be selected to achieve higher yield and purity.
All these methods have their own advantages and disadvantages. Organic synthesizers can choose the best ones according to actual needs, such as the availability of raw materials, cost considerations, and product purity requirements, to form the synthesis of 4- (4-chlorophenoxy) iodobenzene.
First, the method of nucleophilic substitution reaction. Using 4-chlorophenol and iodobenzene derivatives as raw materials, in the presence of alkali, the nucleophilic substitution reaction can occur between the two. Base can promote the deprotonation of 4-chlorophenol phenol hydroxyl group, enhance its nucleophilicity, and then replace the carbon connected to the iodine atom in the iodobenzene derivative to generate 4- (4-chlorophenoxy) iodobenzene. Commonly used bases include potassium carbonate, sodium carbonate, etc. The reaction solvents are mostly N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO) and other aprotonic polar solvents. Such solvents can dissolve raw materials and bases and promote the reaction.
Second, the method of transition metal catalysis. Transition metals such as palladium and copper are used as catalysts to couple 4-chlorophenol with iodobenzene. In palladium catalysis, ligands are often required, such as triphenylphosphine, which can adjust the electron cloud density and spatial structure of palladium catalysts, improve catalytic activity and selectivity. The reaction system also requires the participation of alkali, which can not only promote the activation of phenolic hydroxyl groups, but also adjust the pH of the reaction, which is conducive to the reaction. The method of copper catalysis also has its own unique characteristics. The catalyst price is relatively low, and the reaction conditions may be milder, which can reduce the synthesis cost to a certain extent.
Third, through the method of functional group conversion. First, the functional group of iodobenzene is modified, and groups that are easy to react with 4-chlorophenol are introduced, such as halogen atoms, sulfonate ester groups, etc. After that, the modified iodobenzene derivative is reacted with 4-chlorophenol under suitable conditions. After substitution and other steps, 4- (4-chlorophenoxy) iodobenzene can also be obtained. In this process, the control of the reaction conditions is very critical. According to the characteristics of the introduced functional groups, the appropriate reaction reagents, reaction temperature, time and other conditions should be selected to achieve higher yield and purity.
All these methods have their own advantages and disadvantages. Organic synthesizers can choose the best ones according to actual needs, such as the availability of raw materials, cost considerations, and product purity requirements, to form the synthesis of 4- (4-chlorophenoxy) iodobenzene.
Where is 4- (4-chlorophenoxy) iodobenzene used?
4- (4-chlorophenoxy) iodobenzene is used in various fields. In the field of pharmaceutical research and development, this compound is often a key intermediate. Because of its unique structure, it can be synthesized by organic synthesis, adding specific groups to prepare new drugs with biological activity. Such as the creation of antibacterial drugs, 4- (4-chlorophenoxy) iodobenzene can be introduced into antibacterial functional groups through exquisite reactions, and then become effective antibacterial ingredients.
In materials science, it also has its own function. It may participate in the construction of polymer materials, through polymerization reaction, into the polymer chain, endowing the material with specific properties. Such as improving the thermal stability and mechanical properties of the material, making the material suitable for high temperature and high stress conditions.
Furthermore, in the field of organic synthetic chemistry, this is an important building block. Organic chemists use it to perform cross-coupling reactions to construct complex organic molecular structures. Through palladium-catalyzed coupling reactions, 4- (4-chlorophenoxy) iodobenzene can combine with a variety of nucleophiles, expand the molecular framework, enrich the variety of organic compounds, and provide possibilities for the synthesis of new functional materials and total synthesis of natural products. Therefore, 4- (4-chlorophenoxy) iodobenzene is an indispensable substance in the fields of medicine, materials, and organic synthesis, promoting the development and progress of various fields.
In materials science, it also has its own function. It may participate in the construction of polymer materials, through polymerization reaction, into the polymer chain, endowing the material with specific properties. Such as improving the thermal stability and mechanical properties of the material, making the material suitable for high temperature and high stress conditions.
Furthermore, in the field of organic synthetic chemistry, this is an important building block. Organic chemists use it to perform cross-coupling reactions to construct complex organic molecular structures. Through palladium-catalyzed coupling reactions, 4- (4-chlorophenoxy) iodobenzene can combine with a variety of nucleophiles, expand the molecular framework, enrich the variety of organic compounds, and provide possibilities for the synthesis of new functional materials and total synthesis of natural products. Therefore, 4- (4-chlorophenoxy) iodobenzene is an indispensable substance in the fields of medicine, materials, and organic synthesis, promoting the development and progress of various fields.
What is the market outlook for 4- (4-chlorophenoxy) iodobenzene?
4- (4-chlorophenoxy) iodobenzene is also an organic compound. Its prospects in the market are related to the number of ends.
In the field of autochemical synthesis, this compound is an important intermediary. In the manufacture of fine chemicals, such as the synthesis of specific pharmaceuticals and agricultural chemicals, it is often relied on to participate in the reaction, and through subtle chemical transformation, products with specific functions are produced. At present, pharmaceutical research and development requires high-efficiency and specific active ingredients. The unique structure of 4- (4-chlorophenoxy) iodobenzene may play a key role in the process of new drug creation and help synthesize drugs with novel mechanisms of action. In the pharmaceutical chemical market, its demand may be on the rise.
In the field of materials science, with the advancement of science and technology, the desire for high-performance materials is increasing. 4- (4-chlorophenoxy) iodobenzene can be chemically modified and integrated into polymer materials to improve the electrical and optical properties of materials. For example, in the preparation of organic optoelectronic materials, with its unique electron cloud distribution and spatial structure, it may improve the charge transfer efficiency and light absorption properties of materials, bringing new opportunities for organic Light Emitting Diodes, solar cells and other fields. Therefore, in the emerging material market, its prospects are also quite promising.
However, its market prospects are not entirely smooth. On the one hand, the complexity of the synthesis process and cost considerations are obstacles to its promotion. If you want to mass-produce, you need to optimize the synthesis path, reduce costs and increase efficiency in order to gain an advantage in the market competition. On the other hand, the stricter environmental regulations have put forward higher requirements for waste treatment and Environmental Impact Assessment in the production process. If it cannot fit the concept of green chemistry, or when the market expands, it will encounter many obstacles.
In summary, although 4- (4-chlorophenoxy) iodobenzene has potential opportunities in many fields such as chemical industry, medicine, and materials due to its own structural and performance advantages, it also needs to face challenges such as synthesis costs and environmental protection. If it can be properly dealt with, it will surely bloom and occupy a place in the market.
In the field of autochemical synthesis, this compound is an important intermediary. In the manufacture of fine chemicals, such as the synthesis of specific pharmaceuticals and agricultural chemicals, it is often relied on to participate in the reaction, and through subtle chemical transformation, products with specific functions are produced. At present, pharmaceutical research and development requires high-efficiency and specific active ingredients. The unique structure of 4- (4-chlorophenoxy) iodobenzene may play a key role in the process of new drug creation and help synthesize drugs with novel mechanisms of action. In the pharmaceutical chemical market, its demand may be on the rise.
In the field of materials science, with the advancement of science and technology, the desire for high-performance materials is increasing. 4- (4-chlorophenoxy) iodobenzene can be chemically modified and integrated into polymer materials to improve the electrical and optical properties of materials. For example, in the preparation of organic optoelectronic materials, with its unique electron cloud distribution and spatial structure, it may improve the charge transfer efficiency and light absorption properties of materials, bringing new opportunities for organic Light Emitting Diodes, solar cells and other fields. Therefore, in the emerging material market, its prospects are also quite promising.
However, its market prospects are not entirely smooth. On the one hand, the complexity of the synthesis process and cost considerations are obstacles to its promotion. If you want to mass-produce, you need to optimize the synthesis path, reduce costs and increase efficiency in order to gain an advantage in the market competition. On the other hand, the stricter environmental regulations have put forward higher requirements for waste treatment and Environmental Impact Assessment in the production process. If it cannot fit the concept of green chemistry, or when the market expands, it will encounter many obstacles.
In summary, although 4- (4-chlorophenoxy) iodobenzene has potential opportunities in many fields such as chemical industry, medicine, and materials due to its own structural and performance advantages, it also needs to face challenges such as synthesis costs and environmental protection. If it can be properly dealt with, it will surely bloom and occupy a place in the market.
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