Linshang Chemical
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4-(5-Chloro-2-Methoxybenzamidoethyl)Benzenesulfonamide
Linshang Chemical
|
HS Code |
828572 |
| Chemical Formula | C16H17ClN2O5S |
| Molecular Weight | 384.839 g/mol |
| Appearance | Typically a solid (description may vary) |
| Melting Point | Specific value would require experimental determination |
| Solubility In Water | Limited solubility expected due to its organic nature |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, dichloromethane etc. |
| Logp | Estimated value would indicate lipophilicity, requires calculation |
| Vapor Pressure | Low vapor pressure as it's likely a solid at room conditions |
As an accredited 4-(5-Chloro-2-Methoxybenzamidoethyl)Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram pack of 4-(5 - chloro - 2 - methoxybenzamidoethyl)benzenesulfonamide in sealed container. |
| Storage | Store 4-(5 - chloro - 2 - methoxybenzamidoethyl)benzenesulfonamide in a cool, dry place, away from direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and contamination. Avoid storing near sources of heat or ignition, and separate from incompatible substances to ensure its stability and integrity. |
| Shipping | Ship 4-(5 - chloro - 2 - methoxybenzamidoethyl)benzenesulfonamide in well - sealed, corrosion - resistant containers. Ensure compliance with chemical shipping regulations, with proper labeling for safe transportation. |
Competitive 4-(5-Chloro-2-Methoxybenzamidoethyl)Benzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
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4- (5-chloro-2-methoxybenzamidoethyl) What is the chemical structure of benzenesulfonamide?
4- (5-chloro-2-methoxybenzamidoethyl) benzenesulfonamide, its chemical structure is one of the structures of organic compounds. In this compound structure, the core is the structure of benzenesulfonamide.
On one side of it, there is a benzene ring connected, and at the opposite position of the benzene ring, there is a specific substituent. In this substituent, an ethylamino group is connected to the benzene ring, and the nitrogen atom of the ethylamino group is connected to the carbonyl carbon of the 5-chloro-2-methoxybenzoyl group. That is, the carboxyl group of 5-chloro-2-methoxybenzoic acid is condensed with the amino group of ethylamine to form an amide bond.
Wherein, the 5-chloro-2-methoxybenzoyl moiety is substituted with a chlorine atom at the 5th position, and the methoxy group is substituted with a benzene ring at the 2nd position. The other side is the part composed of the sulfonic acid group and the amino group of benzenesulfonamide. The combination of this chemical structure endows the compound with specific physical and chemical properties, which may be of great significance in the fields of organic synthesis, medicinal chemistry, etc. Due to its unique structure, it may affect its interaction with biological targets, or exhibit unique activity and selectivity in chemical reactions.
On one side of it, there is a benzene ring connected, and at the opposite position of the benzene ring, there is a specific substituent. In this substituent, an ethylamino group is connected to the benzene ring, and the nitrogen atom of the ethylamino group is connected to the carbonyl carbon of the 5-chloro-2-methoxybenzoyl group. That is, the carboxyl group of 5-chloro-2-methoxybenzoic acid is condensed with the amino group of ethylamine to form an amide bond.
Wherein, the 5-chloro-2-methoxybenzoyl moiety is substituted with a chlorine atom at the 5th position, and the methoxy group is substituted with a benzene ring at the 2nd position. The other side is the part composed of the sulfonic acid group and the amino group of benzenesulfonamide. The combination of this chemical structure endows the compound with specific physical and chemical properties, which may be of great significance in the fields of organic synthesis, medicinal chemistry, etc. Due to its unique structure, it may affect its interaction with biological targets, or exhibit unique activity and selectivity in chemical reactions.
4- (5-chloro-2-methoxybenzamidoethyl) What are the main uses of benzenesulfonamide?
4- (5-chloro-2-methoxybenzamidoethyl) benzenesulfonamide is one of the organic compounds. Its main use is quite important in the field of medicinal chemistry.
This compound is often used as a pharmaceutical intermediate. When covering the development of medicine, the synthesis of many drugs depends on it as the basic structure. Through specific chemical reactions, its structure can be modified and modified to obtain new drugs with specific pharmacological activities.
In drug design, the chemical structure of 4- (5-chloro-2-methoxybenzamidoethyl) benzenesulfonamide can provide unique chemical properties and spatial configurations. This property helps it interact with specific targets in the organism, such as binding to proteins, enzymes or receptors, in order to exert therapeutic effect.
For example, it can be used to develop antibacterial drugs. By its structure and specific bacterial targets in vivo, it interferes with the physiological and metabolic processes of bacteria, achieving the purpose of bactericidal or bacteriostatic. Or it can be used for the creation of anti-tumor drugs, by acting on targets related to tumor cells, inhibiting tumor cell proliferation and inducing apoptosis, providing a new path for tumor treatment.
Furthermore, in pharmaceutical chemistry research, this compound is used as a starting material to explore its structure-activity relationship. By systematically changing its substituent or structural part, the effect on biological activity is observed, so as to optimize the design of new drug molecules with stronger activity, better selectivity and less side effects.
From this point of view, 4- (5-chloro-2-methoxybenzamidoethyl) benzenesulfonamide has great potential value and broad application prospects in the field of pharmaceutical research and development, laying the foundation for the creation of new and effective drugs.
This compound is often used as a pharmaceutical intermediate. When covering the development of medicine, the synthesis of many drugs depends on it as the basic structure. Through specific chemical reactions, its structure can be modified and modified to obtain new drugs with specific pharmacological activities.
In drug design, the chemical structure of 4- (5-chloro-2-methoxybenzamidoethyl) benzenesulfonamide can provide unique chemical properties and spatial configurations. This property helps it interact with specific targets in the organism, such as binding to proteins, enzymes or receptors, in order to exert therapeutic effect.
For example, it can be used to develop antibacterial drugs. By its structure and specific bacterial targets in vivo, it interferes with the physiological and metabolic processes of bacteria, achieving the purpose of bactericidal or bacteriostatic. Or it can be used for the creation of anti-tumor drugs, by acting on targets related to tumor cells, inhibiting tumor cell proliferation and inducing apoptosis, providing a new path for tumor treatment.
Furthermore, in pharmaceutical chemistry research, this compound is used as a starting material to explore its structure-activity relationship. By systematically changing its substituent or structural part, the effect on biological activity is observed, so as to optimize the design of new drug molecules with stronger activity, better selectivity and less side effects.
From this point of view, 4- (5-chloro-2-methoxybenzamidoethyl) benzenesulfonamide has great potential value and broad application prospects in the field of pharmaceutical research and development, laying the foundation for the creation of new and effective drugs.
4- (5-chloro-2-methoxybenzamidoethyl) What are the preparation methods of benzenesulfonamide?
To prepare 4 - (5 - chloro - 2 - methoxybenzamidoethyl) benzenesulfonamide, there are various methods.
First, it can be started from the raw material 5 - chloro - 2 - methoxybenzoic acid. The acid is first heated with thionyl chloride to obtain 5 - chloro - 2 - methoxybenzoyl chloride. This reaction needs to be carried out at an appropriate temperature and in an inert atmosphere. Sulfuryl chloride can convert carboxyl groups into acyl chloride groups. After that, the prepared acid chloride is reacted with N- (2-aminoethyl) benzenesulfonamide in the presence of a base, which can neutralize the acid generated by the reaction and promote the forward reaction. Common bases such as triethylamine, etc., so that the target product can be obtained.
Second, 2-methoxy-5-chloroaniline is used as the starting material. The amino group is first protected by a common protecting group such as tert-butoxycarbonyl, and then the protected aniline is condensed with 2 - (benzenesulfonamido) acetic acid in a condensing agent such as 1 - (3 - dimethylaminopropyl) - 3 - ethylcarbodiimide hydrochloride (EDC · HCl) and a catalyst 4 - dimethylaminopyridine (DMAP). After removing the amino protecting group, 4 - (5 - chloro - 2 - methoxybenzamido ethyl) benzenesulfonamide can also be obtained.
Third, benzenesulfonamide can also be considered as a starting material, first introducing 2-chloroethyl, and then reacting with active derivatives of 5-chloro-2-methoxybenzoic acid (such as acid chloride or anhydride). After appropriate reaction conditions and post-treatment, the target compound can also be obtained. It is necessary to pay attention to the conditions of each reaction step, such as temperature, solvent, reactant ratio, etc., which all affect the yield and purity of the reaction and need to be carefully optimized.
First, it can be started from the raw material 5 - chloro - 2 - methoxybenzoic acid. The acid is first heated with thionyl chloride to obtain 5 - chloro - 2 - methoxybenzoyl chloride. This reaction needs to be carried out at an appropriate temperature and in an inert atmosphere. Sulfuryl chloride can convert carboxyl groups into acyl chloride groups. After that, the prepared acid chloride is reacted with N- (2-aminoethyl) benzenesulfonamide in the presence of a base, which can neutralize the acid generated by the reaction and promote the forward reaction. Common bases such as triethylamine, etc., so that the target product can be obtained.
Second, 2-methoxy-5-chloroaniline is used as the starting material. The amino group is first protected by a common protecting group such as tert-butoxycarbonyl, and then the protected aniline is condensed with 2 - (benzenesulfonamido) acetic acid in a condensing agent such as 1 - (3 - dimethylaminopropyl) - 3 - ethylcarbodiimide hydrochloride (EDC · HCl) and a catalyst 4 - dimethylaminopyridine (DMAP). After removing the amino protecting group, 4 - (5 - chloro - 2 - methoxybenzamido ethyl) benzenesulfonamide can also be obtained.
Third, benzenesulfonamide can also be considered as a starting material, first introducing 2-chloroethyl, and then reacting with active derivatives of 5-chloro-2-methoxybenzoic acid (such as acid chloride or anhydride). After appropriate reaction conditions and post-treatment, the target compound can also be obtained. It is necessary to pay attention to the conditions of each reaction step, such as temperature, solvent, reactant ratio, etc., which all affect the yield and purity of the reaction and need to be carefully optimized.
4- (5-chloro-2-methoxybenzamidoethyl) What are the pharmacological properties of benzenesulfonamide?
4- (5-chloro-2-methoxybenzamidoethyl) benzenesulfonamide, this medicine has a mild and special effect. Its properties are good in all meridians, and it has the power of regulating and treating diseases in the human body.
Cover the properties of this medicine, it can dredge qi and make qi and blood flow unimpeded. Those with qi and blood are the foundation of human beings, and if qi and blood are smooth, all diseases will not occur. Therefore, in the case of qi blockade, it has the ability to open depression and disperse knots, and can relieve chest tightness and hypochondriac pain.
It can also clear heat and cool blood, and has the effect of clearing away heat in the body, such as fever and irritability. If the heat evil is gone, the viscera will be peaceful and the spirit will be cleared.
And it has the power of relieving pain in harmony, which can reconcile the spleen and stomach, slow down and relieve pain, make the spleen and stomach transport orderly, and eliminate diet.
Furthermore, this medicine can also detoxify and reduce swelling. If the skin is invaded by poisonous evil, and there is a disease of sores and swelling, it can drive out the poison, dissipate the swelling and make the skin return to normal.
However, the way of medicine, when evaluating the situation, carefully observing the condition, and considering the dosage, can make the best use of this medicine and avoid its harm. Doctors use medication, such as the use of soldiers, need to be careful and delicate in order to cure the disease and restore the patient's health as soon as possible.
Cover the properties of this medicine, it can dredge qi and make qi and blood flow unimpeded. Those with qi and blood are the foundation of human beings, and if qi and blood are smooth, all diseases will not occur. Therefore, in the case of qi blockade, it has the ability to open depression and disperse knots, and can relieve chest tightness and hypochondriac pain.
It can also clear heat and cool blood, and has the effect of clearing away heat in the body, such as fever and irritability. If the heat evil is gone, the viscera will be peaceful and the spirit will be cleared.
And it has the power of relieving pain in harmony, which can reconcile the spleen and stomach, slow down and relieve pain, make the spleen and stomach transport orderly, and eliminate diet.
Furthermore, this medicine can also detoxify and reduce swelling. If the skin is invaded by poisonous evil, and there is a disease of sores and swelling, it can drive out the poison, dissipate the swelling and make the skin return to normal.
However, the way of medicine, when evaluating the situation, carefully observing the condition, and considering the dosage, can make the best use of this medicine and avoid its harm. Doctors use medication, such as the use of soldiers, need to be careful and delicate in order to cure the disease and restore the patient's health as soon as possible.
4- (5-chloro-2-methoxybenzamidoethyl) What are the potential side effects of benzenesulfonamide?
4- (5-chloro-2-methoxybenzamidoethyl) benzenesulfonamide, although this medicine has healing power, it also has some hidden side effects, which cannot be ignored.
First, the digestive system is often disturbed by it. Taking it may cause nausea and vomiting, like waves in the abdomen, and stomach qi is reversed. What's more, vomiting is excessive, and what you eat is poured out. There are also symptoms of abdominal pain, which may be mild or severe, and the parts are mostly between the abdomen, such as needle prickling pain, and it is uncomfortable like knots. And the appearance of diarrhea is not uncommon, the stool is loose, the number of times increases, several times a day, making the patient sleepy.
Second, it also affects the blood system. Or reduce the number of white blood cells, if the body's defense barrier is weakened, the power to resist external evil is reduced, and it is easy to be invaded by evil spirits such as wind cold and summer dampness, causing various exogenous diseases. The number of platelets may also be reduced, the coagulation function is hindered, and the body surface or petechiae and petechiae are present. Minor collisions can easily cause subcutaneous bleeding, and if internal organs bleed, it is extremely dangerous.
Third, the nervous system is also unavoidable. I often feel dizzy, and when I stand and walk, I feel like I am in a cloud, unsteady, and I feel shaky. Headaches also occur from time to time, either for bloating pain, or for jumping pain. The pain is mostly near the temples on both sides, or on the top of the head and the back of the pillow, which makes people upset and difficult to get comfortable. And it is easy to cause insomnia, tossing and turning at night, and it is difficult to fall asleep. Even if you fall asleep, you often dream and wake up easily, resulting in daytime mental weakness, which affects everything.
Fourth, the skin will also be abnormal. Or rash, different shapes, or erythema, or like a pimple, itching is intolerable, after scratching, the rash becomes more serious, or even ulceration and exudation, affecting the health and beauty of the skin.
When a doctor uses this medicine, they must weigh its advantages and disadvantages. Patients should also carefully investigate their own symptoms. If there is any abnormality, please inform the doctor immediately for appropriate measures.
First, the digestive system is often disturbed by it. Taking it may cause nausea and vomiting, like waves in the abdomen, and stomach qi is reversed. What's more, vomiting is excessive, and what you eat is poured out. There are also symptoms of abdominal pain, which may be mild or severe, and the parts are mostly between the abdomen, such as needle prickling pain, and it is uncomfortable like knots. And the appearance of diarrhea is not uncommon, the stool is loose, the number of times increases, several times a day, making the patient sleepy.
Second, it also affects the blood system. Or reduce the number of white blood cells, if the body's defense barrier is weakened, the power to resist external evil is reduced, and it is easy to be invaded by evil spirits such as wind cold and summer dampness, causing various exogenous diseases. The number of platelets may also be reduced, the coagulation function is hindered, and the body surface or petechiae and petechiae are present. Minor collisions can easily cause subcutaneous bleeding, and if internal organs bleed, it is extremely dangerous.
Third, the nervous system is also unavoidable. I often feel dizzy, and when I stand and walk, I feel like I am in a cloud, unsteady, and I feel shaky. Headaches also occur from time to time, either for bloating pain, or for jumping pain. The pain is mostly near the temples on both sides, or on the top of the head and the back of the pillow, which makes people upset and difficult to get comfortable. And it is easy to cause insomnia, tossing and turning at night, and it is difficult to fall asleep. Even if you fall asleep, you often dream and wake up easily, resulting in daytime mental weakness, which affects everything.
Fourth, the skin will also be abnormal. Or rash, different shapes, or erythema, or like a pimple, itching is intolerable, after scratching, the rash becomes more serious, or even ulceration and exudation, affecting the health and beauty of the skin.
When a doctor uses this medicine, they must weigh its advantages and disadvantages. Patients should also carefully investigate their own symptoms. If there is any abnormality, please inform the doctor immediately for appropriate measures.
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