Linshang Chemical
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4,5-Dichlorobenzene-1,2-Dicarboxylic Acid
Linshang Chemical
|
HS Code |
908989 |
| Chemical Formula | C8H4Cl2O4 |
| Molar Mass | 235.02 g/mol |
| Appearance | White to off - white solid |
| Melting Point | 219 - 223 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in some organic solvents like ethanol, acetone |
| Density | Approx. 1.62 g/cm³ |
| Acidity | Weakly acidic due to carboxylic acid groups |
| Pka | Typically around 2 - 4 for each carboxylic acid group |
| Stability | Stable under normal conditions, but may react with strong bases and oxidizing agents |
As an accredited 4,5-Dichlorobenzene-1,2-Dicarboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4,5 - dichlorobenzene - 1,2 - dicarboxylic acid packaged in a sealed plastic bag. |
| Storage | 4,5 - Dichlorobenzene - 1,2 - dicarboxylic acid should be stored in a cool, dry, and well - ventilated area. Keep it away from sources of heat, ignition, and incompatible substances such as strong oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and potential reactions, ensuring its stability during storage. |
| Shipping | 4,5 - dichlorobenzene - 1,2 - dicarboxylic Acid is shipped in properly sealed, corrosion - resistant containers. Packaging adheres to chemical transport regulations to prevent leakage during transit, ensuring safety. |
Competitive 4,5-Dichlorobenzene-1,2-Dicarboxylic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4,5-Dichlorobenzene-1,2-Dicarboxylic Acid in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4,5-Dichlorobenzene-1,2-Dicarboxylic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4,5-dichlorobenzene-1,2-dicarboxylic acid?
4,5-Difluorobenzene-1,2-dicarboxylic acid is a class of organic compounds. Its main uses are quite extensive.
In the field of medicinal chemistry, this compound is often a key intermediate in the synthesis of many specific drugs. Due to the unique properties of fluorine atoms, it can significantly change the physical, chemical and biological activities of compounds. By introducing the structure of 4,5-difluorobenzene-1,2-dicarboxylic acid, the synthesized drug may have better bioavailability, can more effectively penetrate the biofilm and reach the target of action; or have higher selectivity, can precisely act on specific biomolecules, reduce the adverse effects on other cells or tissues.
In the field of materials science, it also has outstanding performance. Using this as a raw material, polymer materials with excellent properties can be prepared. The obtained materials may have excellent thermal stability and can still maintain good physical properties in high temperature environments without deformation or decomposition; or have unique optical properties, such as good light transmittance and fluorescence properties, which can be applied to optical devices, display materials and other fields.
In the research and development of pesticides, 4,5-difluorobenzene-1,2-dicarboxylic acid also plays an important role. Pesticides synthesized on this basis may have stronger killing or inhibitory effects on specific pests and pathogens, and due to their structural characteristics or lower environmental toxicity, they are more in line with today's green environmental protection concept. When applied to farmland, they can effectively reduce the harm to soil, water sources, and non-target organisms.
In the field of medicinal chemistry, this compound is often a key intermediate in the synthesis of many specific drugs. Due to the unique properties of fluorine atoms, it can significantly change the physical, chemical and biological activities of compounds. By introducing the structure of 4,5-difluorobenzene-1,2-dicarboxylic acid, the synthesized drug may have better bioavailability, can more effectively penetrate the biofilm and reach the target of action; or have higher selectivity, can precisely act on specific biomolecules, reduce the adverse effects on other cells or tissues.
In the field of materials science, it also has outstanding performance. Using this as a raw material, polymer materials with excellent properties can be prepared. The obtained materials may have excellent thermal stability and can still maintain good physical properties in high temperature environments without deformation or decomposition; or have unique optical properties, such as good light transmittance and fluorescence properties, which can be applied to optical devices, display materials and other fields.
In the research and development of pesticides, 4,5-difluorobenzene-1,2-dicarboxylic acid also plays an important role. Pesticides synthesized on this basis may have stronger killing or inhibitory effects on specific pests and pathogens, and due to their structural characteristics or lower environmental toxicity, they are more in line with today's green environmental protection concept. When applied to farmland, they can effectively reduce the harm to soil, water sources, and non-target organisms.
What are the physical properties of 4,5-dichlorobenzene-1,2-dicarboxylic acid?
4,5-Difluorobenzoic acid-1,2-dicarboxylic acid is a genus of organic compounds. Its physical properties are unique, and I will describe them in detail for you.
Looking at its properties, it is often in the form of white to off-white crystalline powder. This is its external characteristic, which shows its unique form where it can be seen. Its melting point is quite critical, about a certain temperature range. This temperature range is an important indicator for defining its physical state transformation. When the temperature rises to this specific range, it will gradually melt from the solid state to the liquid state. The characteristics of this melting point are of great significance in the identification and purification of compounds.
Furthermore, its solubility is also a major characteristic. In organic solvents, such as common ethanol, ether, etc., it has a certain solubility. This property allows it to participate in many chemical reactions and industrial processes in the form of solutions, which facilitates the smooth progress of the reaction. In water, its solubility is relatively limited. This difference reflects the different interactions between the compound and different solvents, and also affects its behavior in different environments.
In addition, the stability of the compound is also worth mentioning. Under normal temperature and pressure without special chemical reactions, its chemical structure is relatively stable and can maintain its inherent properties. However, in case of high temperature, strong oxidants or specific chemical reaction conditions, its structure may change and other compounds may be derived.
Its physical properties are of great value in the fields of chemical industry and medicine. In chemical synthesis, the reaction conditions and separation and purification steps can be reasonably planned according to its melting point, solubility and other characteristics; in pharmaceutical research and development, its stability and interaction with the biological environment, or related to the efficacy and safety of drugs, provide a basic basis for the creation of new drugs.
Looking at its properties, it is often in the form of white to off-white crystalline powder. This is its external characteristic, which shows its unique form where it can be seen. Its melting point is quite critical, about a certain temperature range. This temperature range is an important indicator for defining its physical state transformation. When the temperature rises to this specific range, it will gradually melt from the solid state to the liquid state. The characteristics of this melting point are of great significance in the identification and purification of compounds.
Furthermore, its solubility is also a major characteristic. In organic solvents, such as common ethanol, ether, etc., it has a certain solubility. This property allows it to participate in many chemical reactions and industrial processes in the form of solutions, which facilitates the smooth progress of the reaction. In water, its solubility is relatively limited. This difference reflects the different interactions between the compound and different solvents, and also affects its behavior in different environments.
In addition, the stability of the compound is also worth mentioning. Under normal temperature and pressure without special chemical reactions, its chemical structure is relatively stable and can maintain its inherent properties. However, in case of high temperature, strong oxidants or specific chemical reaction conditions, its structure may change and other compounds may be derived.
Its physical properties are of great value in the fields of chemical industry and medicine. In chemical synthesis, the reaction conditions and separation and purification steps can be reasonably planned according to its melting point, solubility and other characteristics; in pharmaceutical research and development, its stability and interaction with the biological environment, or related to the efficacy and safety of drugs, provide a basic basis for the creation of new drugs.
What are the chemical properties of 4,5-dichlorobenzene-1,2-dicarboxylic acid?
The chemical properties of 4,5-difluorobenzene-1,2-dicarboxylic acid are particularly important and are related to the process of many chemical changes. This compound is acidic because it contains a carboxyl group (-COOH) functional group. The carboxyl group can react with the base in a neutral manner, just like acetic acid interacts with sodium hydroxide to form sodium acetate and water. In case of base, 4,5-difluorobenzene-1,2-dicarboxylic acid also produces corresponding salts and water.
Furthermore, the carboxyl group can participate in the esterification reaction. When catalyzed by acid with alcohols, ester compounds can be formed. For example, ethanol and acetic acid under the catalysis of sulfuric acid form ethyl acetate and water. This 4,5-difluorobenzene-1,2-dicarboxylic acid can also react with alcohols in this way to produce esters with specific aromas and properties, which are quite useful in flavors, medicine and other industries.
It contains fluorine atoms, and the electronegativity of fluorine atoms is extremely high, which has a great impact on the electron cloud distribution and chemical activity of molecules. Due to the electron-absorbing effect of fluorine atoms, the electron cloud density of the benzene ring decreases, which increases the difficulty of electrophilic substitution reactions on the benzene ring. At the same time, it also makes the compound have special stability and biological activity. In medicinal chemistry, fluorine-containing compounds often become key structural units for the development of new drugs due to their unique activities.
In addition, the carboxyl group of 4,5-difluorobenzene-1,2-dicarboxylic acid can be converted into alcohol hydroxyl group by reduction reaction. With appropriate reducing agent, such as lithium aluminum hydride (LiAlH) treatment, the carboxyl group can be reduced to the corresponding alcohol. This reaction broadens its use in organic synthesis, and can further derive a variety of different types of compounds, which is an important step in organic synthesis chemistry.
In short, 4,5-difluorobenzene-1,2-dicarboxylic acid has various chemical properties due to its structure of carboxyl groups and fluorine atoms. It has important applications in many fields such as chemical industry, medicine, materials, etc. It is an object of attention in organic chemistry research and practical production.
Furthermore, the carboxyl group can participate in the esterification reaction. When catalyzed by acid with alcohols, ester compounds can be formed. For example, ethanol and acetic acid under the catalysis of sulfuric acid form ethyl acetate and water. This 4,5-difluorobenzene-1,2-dicarboxylic acid can also react with alcohols in this way to produce esters with specific aromas and properties, which are quite useful in flavors, medicine and other industries.
It contains fluorine atoms, and the electronegativity of fluorine atoms is extremely high, which has a great impact on the electron cloud distribution and chemical activity of molecules. Due to the electron-absorbing effect of fluorine atoms, the electron cloud density of the benzene ring decreases, which increases the difficulty of electrophilic substitution reactions on the benzene ring. At the same time, it also makes the compound have special stability and biological activity. In medicinal chemistry, fluorine-containing compounds often become key structural units for the development of new drugs due to their unique activities.
In addition, the carboxyl group of 4,5-difluorobenzene-1,2-dicarboxylic acid can be converted into alcohol hydroxyl group by reduction reaction. With appropriate reducing agent, such as lithium aluminum hydride (LiAlH) treatment, the carboxyl group can be reduced to the corresponding alcohol. This reaction broadens its use in organic synthesis, and can further derive a variety of different types of compounds, which is an important step in organic synthesis chemistry.
In short, 4,5-difluorobenzene-1,2-dicarboxylic acid has various chemical properties due to its structure of carboxyl groups and fluorine atoms. It has important applications in many fields such as chemical industry, medicine, materials, etc. It is an object of attention in organic chemistry research and practical production.
What are the synthesis methods of 4,5-dichlorobenzene-1,2-dicarboxylic acid?
The synthesis method of 4,5-difluorobenzene-1,2-dicarboxylic acid covers various paths. One is to use fluorobenzene as the starting material and undergo a series of reactions such as halogenation and carboxylation. If a specific fluorobenzene is halogenated first and a halogen atom is introduced, the halogen atom has high activity and can be used as a key check point in subsequent reactions. Next, with a suitable carboxylation reagent, the halogen atom is replaced by a carboxyl group to construct the carboxyl structure of the target molecule. After carefully adjusting the reaction conditions in multiple steps, the synthesis of 4,5-difluorobenzene-1,2-dicarboxylic acid is gradually achieved.
Furthermore, other aromatic hydrocarbons are also used as starting materials, and they are first modified and modified, introducing fluorine atoms and corresponding functional groups, and then undergoing cyclization, oxidation and other reaction steps. For example, through clever reaction strategies, aromatic hydrocarbons are converted into intermediates with specific structures. This intermediate is cyclized appropriately to construct a benzene ring framework, and then through the oxidation process, the specific group is oxidized to a carboxyl group, and the position and quantity of fluorine atoms are ensured to meet the requirements of the target product, and 4,5-difluorobenzene-1,2-dicarboxylic acid is finally obtained.
Another method is to synthesize the compound containing carboxyl groups and fluorine atoms through functional group conversion and structural modification. Such compounds undergo specific reaction conditions to transform some functional groups, and at the same time precisely modify the molecular structure, such as through reduction, substitution and other reactions, gradually adjust the molecular structure, and finally realize the synthesis of 4,5-difluorobenzene-1,2-dicarboxylic acid. All methods need to control the reaction conditions in detail, such as temperature, catalyst, reaction time, etc., in order to achieve the optimal synthesis effect.
Furthermore, other aromatic hydrocarbons are also used as starting materials, and they are first modified and modified, introducing fluorine atoms and corresponding functional groups, and then undergoing cyclization, oxidation and other reaction steps. For example, through clever reaction strategies, aromatic hydrocarbons are converted into intermediates with specific structures. This intermediate is cyclized appropriately to construct a benzene ring framework, and then through the oxidation process, the specific group is oxidized to a carboxyl group, and the position and quantity of fluorine atoms are ensured to meet the requirements of the target product, and 4,5-difluorobenzene-1,2-dicarboxylic acid is finally obtained.
Another method is to synthesize the compound containing carboxyl groups and fluorine atoms through functional group conversion and structural modification. Such compounds undergo specific reaction conditions to transform some functional groups, and at the same time precisely modify the molecular structure, such as through reduction, substitution and other reactions, gradually adjust the molecular structure, and finally realize the synthesis of 4,5-difluorobenzene-1,2-dicarboxylic acid. All methods need to control the reaction conditions in detail, such as temperature, catalyst, reaction time, etc., in order to achieve the optimal synthesis effect.
What is the price range of 4,5-dichlorobenzene-1,2-dicarboxylic acid in the market?
I have not heard of the price of 4,5-difluorobenzene-1,2-dicarboxylic acid on the market. However, if you want to know its price, you should consider all the reasons in detail.
First, the price of raw materials. The preparation of this compound requires specific raw materials, and the price of raw materials fluctuates, which will cause the price of this product to change. If the raw materials are rare or difficult to prepare, the price must be high; if the raw materials are abundant and easy to obtain, the price may be slightly flat.
Second, the method of preparation. The simplicity and difficulty of the preparation process are related to the cost. The delicate and efficient method may reduce the cost. However, if the process is complicated, expensive reagents, special equipment are required, or it takes a long time, the cost will increase, and the price will follow.
Third, the supply and demand of the city. If there are many people who need this product, but there are few products, the supply is in short supply, and the price will rise; if there are too many products, and there are few people who need it, the supply will exceed the demand, and the price will go down.
Fourth, laws and policies and transportation. If regulations limit the preparation and sale of it, or the cost will increase; the distance and difficulty of transportation will also affect its final selling price.
If you want to know the market price of 4,5-difluorobenzene-1,2-dicarboxylic acid, you should check the chemical market information carefully, consult the merchants and manufacturers in the industry, and compare the quotations of various companies to know the approximate range of the price. However, the market situation changes, and the price is difficult to determine. It is necessary to pay attention to it from time to time to get a real-time price.
First, the price of raw materials. The preparation of this compound requires specific raw materials, and the price of raw materials fluctuates, which will cause the price of this product to change. If the raw materials are rare or difficult to prepare, the price must be high; if the raw materials are abundant and easy to obtain, the price may be slightly flat.
Second, the method of preparation. The simplicity and difficulty of the preparation process are related to the cost. The delicate and efficient method may reduce the cost. However, if the process is complicated, expensive reagents, special equipment are required, or it takes a long time, the cost will increase, and the price will follow.
Third, the supply and demand of the city. If there are many people who need this product, but there are few products, the supply is in short supply, and the price will rise; if there are too many products, and there are few people who need it, the supply will exceed the demand, and the price will go down.
Fourth, laws and policies and transportation. If regulations limit the preparation and sale of it, or the cost will increase; the distance and difficulty of transportation will also affect its final selling price.
If you want to know the market price of 4,5-difluorobenzene-1,2-dicarboxylic acid, you should check the chemical market information carefully, consult the merchants and manufacturers in the industry, and compare the quotations of various companies to know the approximate range of the price. However, the market situation changes, and the price is difficult to determine. It is necessary to pay attention to it from time to time to get a real-time price.
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