4-Amino-2,5-Dichlorobenzenesulfonic Acid
Linshang Chemical
HS Code |
453205 |
Chemical Formula | C6H3Cl2NO3S |
Molecular Weight | 242.06 |
Appearance | Solid (usually white or off - white powder) |
Solubility In Water | Soluble to a certain extent |
Melting Point | Typically in a specific range (data needed for exact value) |
Boiling Point | Requires experimental data for exact value |
Density | Needs experimental determination |
Pka Value | Determines its acidic strength (data required) |
Flash Point | Value depends on experimental measurement |
Odor | May have a characteristic odor (description may vary) |
As an accredited 4-Amino-2,5-Dichlorobenzenesulfonic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 25 - kg bag packaging for 4 - amino - 2,5 - dichlorobenzenesulfonic Acid. |
Storage | 4 - amino - 2,5 - dichlorobenzenesulfonic acid should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and incompatible substances like strong oxidizers. Store it in a tightly closed container to prevent moisture absorption and contamination, which could affect its chemical properties and purity. |
Shipping | 4 - amino - 2,5 - dichlorobenzenesulfonic acid is shipped in tightly sealed containers, compliant with chemical transportation regulations. Care is taken to prevent spills, ensuring safe transit to destination. |
Competitive 4-Amino-2,5-Dichlorobenzenesulfonic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 4-Amino-2,5-Dichlorobenzenesulfonic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of medicine, it is also of great significance. Its special chemical structure may become a starting material or key intermediate for drug synthesis. Through chemical modification and transformation, it is expected to construct compounds with specific pharmacological activities for the development of new drugs to fight various diseases. In the preparation of some functional materials, 4-amino-2,5-dichlorobenzenesulfonic acid can also play a role. For example, in the synthesis of specific polymer materials, the introduction of this structural unit can endow the material with unique properties, such as improving the solubility and thermal stability of the material, or endowing it with special optical and electrical properties, etc., so as to meet the needs of different fields for special materials.
Under normal temperature, it is mostly white to light yellow crystalline powder, which is easy to identify and handle. Its light color indicates that the molecular structure is relatively stable and does not contain too many chromogenic groups that are prone to dark color.
When it comes to solubility, 4-amino-2,5-dichlorobenzenesulfonic acid can exhibit some solubility in water. The cover has a hydrophilic functional group of sulfonic acid in its molecular structure, and the electronegativity of sulfur atoms and oxygen atoms in sulfonic acid groups is significantly different, forming strong polar bonds, which can form hydrogen bonds with water molecules, thereby promoting its dissolution in water; however, some parts such as benzene rings are hydrophobic, which limits their solubility to a certain extent. In polar organic solvents, such as ethanol, it also has a certain solubility. This is because the polarity of the ethanol molecule can interact with some groups of the compound, but the degree of dissolution may vary depending on the complex relationship of intermolecular forces.
As for the melting point, 4-amino-2,5-dichlorobenzenesulfonic acid has a specific melting point value. The melting point is closely related to the intermolecular forces, and there are hydrogen bonds, van der Waals forces, and other interactions between molecules. The amino group and sulfonic acid group in the molecule can form hydrogen bonds, which enhances the intermolecular attraction, so that it needs a higher temperature to overcome this force and realize the transition from solid state to liquid state. The specific melting point value needs to be accurately determined by experiments.
The density of 4-amino-2,5-dichlorobenzenesulfonic acid is also an inherent physical property. The density reflects the mass of a substance per unit volume and is determined by its molecular structure and packing method. The type and arrangement of atoms in the molecular structure of the compound are fixed, and the degree of intermolecular packing is specific, which determines its density.
In addition, its odor is weak. Because the molecular structure does not contain volatile and strong odor groups, the number of molecules volatilized into the air is limited at room temperature and pressure, making it difficult to induce obvious odor perception.
The above physical properties are of great significance in the fields of chemical industry and medicine. In chemical synthesis, a suitable reaction solvent can be selected according to the solubility, and the reaction process and product purity can be controlled by the melting point characteristics. In pharmaceutical research and development, its physical properties may affect the pharmacological processes such as drug absorption and distribution, which are crucial to the design of drug dosage forms and the play of drug efficacy.
Looking at its acidity, it can ionize hydrogen ions in water due to the presence of sulfonic acid groups (-SO and H), which is acidic and can neutralize with bases to generate corresponding salts and water. If it reacts with sodium hydroxide, the hydrogen in the sulfonic acid group combines with the hydroxide in sodium hydroxide to form water, resulting in 4-amino-2,5-dichlorobenzenesulfonic acid sodium.
Its amino (-NH2O) properties cannot be ignored. Amino groups are alkaline, can accept protons, and can react with acids under specific conditions. For example, when reacting with hydrochloric acid, the amino group can bind hydrogen ions to form a positively charged ammonium salt structure. Although the chlorine atom in the
molecule is not as easy to leave as some active halogen atoms, under appropriate nucleophilic substitution reaction conditions, the chlorine atom can be replaced by other nucleophilic reagents. For example, under more severe conditions such as strong alkalinity and high temperature, hydroxyl and other nucleophilic reagents may replace chlorine atoms.
In terms of stability, the compound is relatively stable, but in view of its containing a variety of functional groups, the molecular structure may change under extreme conditions such as strong acids, strong bases, high temperatures, and strong oxidants. With these chemical properties, 4-amino-2,5-dichlorobenzenesulfonic acid can be used as an important intermediate in the field of dye synthesis, using its functional groups to participate in the reaction to construct complex dye molecular structures; in pharmaceutical chemistry, it may also participate in the design and synthesis of drug molecules due to these properties, providing a key structural unit for the development of new drugs.
The starting material is usually based on 2,5-dichloroaniline. First, 2,5-dichloroaniline is placed in an appropriate reactor, and sulfuric acid is used as the sulfonating agent. This is a key step. The amount of sulfuric acid, the reaction temperature and time need to be carefully regulated.
The reaction temperature is generally maintained at a specific range. In the initial stage, it is appropriate to slowly heat up, so that the material is evenly heated and fully mixed. When the reaction starts, the temperature needs to rise and fall moderately according to the process. If the temperature is too low, the reaction will be slow and time-consuming; if the temperature is too high, it may cause side reactions to cluster and the product will be impure.
The reaction time depends on the reaction process and the test results. During this period, chemical analysis methods, such as thin layer chromatography, high performance liquid chromatography, etc., are often used to monitor the progress of the reaction to ensure that the reaction reaches the expected degree.
After the sulfonation reaction is completed, it is also important to separate and purify the product. The reaction mixture is cooled first, or crystals can be precipitated. Then the crude product is obtained by filtration. The crude product still contains impurities and needs to be purified by recrystallization. Select a suitable solvent to dissolve the crude product. After heating, cooling, filtering and other operations, pure 4-amino-2,5-dichlorobenzenesulfonic acid can be obtained.
In addition, during the reaction process, in order to achieve better results, or add an appropriate amount of catalyst to promote the reaction rate, and ensure the selectivity of the reaction, reduce unnecessary side reactions. When operating, also pay attention to safety, sulfuric acid is highly corrosive, be sure to follow the operating procedures and take protective measures.
First, store. First, choose a cool, dry and well-ventilated place. If it is in a humid place, this acid is prone to moisture, causing its quality to be damaged, or causing a chemical reaction that reduces its effectiveness. Second, it must be stored in isolation from oxidants, bases, etc. Because it has specific chemical properties, it may react violently with oxidants, causing the risk of explosion; if it is mixed with bases, it is easy to neutralize and lose its original properties. Third, the storage place should be prepared to contain the leaked materials accordingly, just in case of leakage, and can be stored in time to prevent its spread and cause greater harm.
Second described transportation. When transporting, the packaging must be tight. If the packaging is damaged, the acid leakage will not only pollute the environment, but also pose a threat to the transportation personnel. Transportation vehicles should be equipped with corresponding fire equipment and leakage emergency treatment equipment to prepare for accidents. During transportation, it is important to drive safely to avoid bumps and collisions, and to prevent material leakage caused by packaging damage. At the same time, transportation personnel should also be familiar with the characteristics of this acid and emergency treatment methods. In case of emergencies, they can respond quickly and properly.
In short, 4-amino-2,5-dichlorobenzenesulfonic acid must be stored and transported in accordance with relevant regulations, with due attention to details, to ensure safety and avoid accidents.

Scan to WhatsApp