Linshang Chemical
PRODUCTS
4-Amino-2-Chloro-5-(1H-Tetrazol-5Yl)Benzenesulfonamide
Linshang Chemical
|
HS Code |
658853 |
| Chemical Formula | C7H6ClN5O2S |
| Molar Mass | 261.67 g/mol |
| Solubility In Water | Limited solubility expected due to its relatively non - polar aromatic structure with polar functional groups |
| Solubility In Organic Solvents | May be soluble in polar organic solvents like DMSO, DMF |
| Vapor Pressure | Low vapor pressure expected as it is likely a solid at room temperature |
As an accredited 4-Amino-2-Chloro-5-(1H-Tetrazol-5Yl)Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - amino - 2 - chloro - 5 - (1h - tetrazol - 5yl)benzenesulfonamide in sealed plastic bags. |
| Storage | Store 4 - amino - 2 - chloro - 5 - (1H - tetrazol - 5yl)benzenesulfonamide in a cool, dry place away from direct sunlight. Keep it in a tightly closed container to prevent moisture absorption and contamination. Avoid storing near oxidizing agents or reactive chemicals. Follow local safety regulations regarding its storage for optimal stability and safety. |
| Shipping | 4 - amino - 2 - chloro - 5 - (1H - tetrazol - 5yl)benzenesulfonamide is shipped in accordance with chemical transport regulations. Packed securely in suitable containers, ensuring proper handling to prevent damage and maintain safety during transit. |
Competitive 4-Amino-2-Chloro-5-(1H-Tetrazol-5Yl)Benzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Amino-2-Chloro-5-(1H-Tetrazol-5Yl)Benzenesulfonamide in China?
As a trusted 4-Amino-2-Chloro-5-(1H-Tetrazol-5Yl)Benzenesulfonamide manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Amino-2-Chloro-5-(1H-Tetrazol-5Yl)Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 4-amino-2-chloro-5- (1h-tetrazol-5yl) benzenesulfonamide?
4-Amino-2-chloro-5- (1h-tetrazol-5yl) benzenesulfonamide is the English name of an organic compound, and its chemical structure is as follows.
This compound contains a benzene ring, which is an important structural unit of many organic compounds. At position 4 of the benzene ring, there is an amino group (-NH ²) connected. The amino group has a certain electron-giving property, which affects the electron cloud density distribution of the benzene ring, and can participate in a variety of chemical reactions, such as nucleophilic substitution and salt formation with acids. The chlorine atom (-Cl) is attached at position 2. The chlorine atom has an electron-absorbing induction effect, which can reduce the electron cloud density of the benzene ring and affect the electrophilic substitution reaction activity and position selectivity on the benzene ring.
At position 5, 1H-tetrazole-5-group is connected. 1H-tetrazole-5-group is composed of a five-membered ring, which contains four nitrogen atoms and one carbon atom, and its structure is relatively unique. Due to the existence of nitrogen atoms, the tetrazole ring has a certain basic nature, can bind to protons, and can participate in reactions in coordination chemistry and other fields.
At the same time, the benzene ring is also connected with a benzene sulfonamide group (SO 2O NH 2O). In the sulfonamide group, the sulfur atom is connected to two oxygen atoms by a double bond, and is connected to the amino group. This structure endows the compound with certain polarity and chemical activity. Sulfonamide groups are very important in the fields of medicinal chemistry, and can often affect the biological activity and solubility of the compound.
The structure of each part of this compound affects each other, jointly determining its physical and chemical properties and chemical reactivity. It may have potential application value in the fields of organic synthesis and drug research and development.
This compound contains a benzene ring, which is an important structural unit of many organic compounds. At position 4 of the benzene ring, there is an amino group (-NH ²) connected. The amino group has a certain electron-giving property, which affects the electron cloud density distribution of the benzene ring, and can participate in a variety of chemical reactions, such as nucleophilic substitution and salt formation with acids. The chlorine atom (-Cl) is attached at position 2. The chlorine atom has an electron-absorbing induction effect, which can reduce the electron cloud density of the benzene ring and affect the electrophilic substitution reaction activity and position selectivity on the benzene ring.
At position 5, 1H-tetrazole-5-group is connected. 1H-tetrazole-5-group is composed of a five-membered ring, which contains four nitrogen atoms and one carbon atom, and its structure is relatively unique. Due to the existence of nitrogen atoms, the tetrazole ring has a certain basic nature, can bind to protons, and can participate in reactions in coordination chemistry and other fields.
At the same time, the benzene ring is also connected with a benzene sulfonamide group (SO 2O NH 2O). In the sulfonamide group, the sulfur atom is connected to two oxygen atoms by a double bond, and is connected to the amino group. This structure endows the compound with certain polarity and chemical activity. Sulfonamide groups are very important in the fields of medicinal chemistry, and can often affect the biological activity and solubility of the compound.
The structure of each part of this compound affects each other, jointly determining its physical and chemical properties and chemical reactivity. It may have potential application value in the fields of organic synthesis and drug research and development.
What are the main uses of 4-amino-2-chloro-5- (1h-tetrazol-5yl) benzenesulfonamide
4-Amino-2-chloro-5- (1H-tetrazole-5-yl) benzenesulfonamide, a fine chemical, has important uses in many fields.
In the field of medicine, it is a key class of drug intermediates. Drug developers often use this as a starting material through a series of delicate chemical reactions to construct compounds with specific pharmacological activities. Due to its unique chemical structure, it can be combined with specific targets in organisms or participate in key physiological and biochemical reactions, so it plays an indispensable role in the development of new antibacterial, anti-inflammatory, anti-tumor and other drugs. For example, in the creation of some new antibacterial drugs, the structure of this compound can be modified to cause damage to the cell membrane or cell wall of specific bacteria, and then achieve antibacterial effect.
In the field of pesticides, it also plays an important role. It can be used as a pesticide intermediate to synthesize high-efficiency, low-toxicity and environmentally friendly pesticides. With its chemical properties, it can participate in the synthesis of pesticides with special insecticidal, bactericidal or herbicidal properties. For example, synthetic new insecticides can precisely act on the nervous system of pests, interfere with their normal physiological activities, and achieve high-efficiency insecticides. At the same time, it has less pollution to the environment, which is in line with the needs of the current development of green agriculture.
In the field of materials science, 4-amino-2-chloro-5- (1H-tetrazole-5-yl) benzenesulfonamide also shows unique value. Because of its specific functional groups, it can be used as a functional monomer to participate in the synthesis of polymer materials. By polymerizing with other monomers, the material is endowed with special properties such as antibacterial and antioxidant. For example, in the preparation of some special-purpose plastics or fibers, the addition of this compound can make the material have self-cleaning, antibacterial and antifungal properties, and expand the application range of the material, which can be used in food packaging, medical and hygiene products and other fields with high hygiene requirements.
In the field of medicine, it is a key class of drug intermediates. Drug developers often use this as a starting material through a series of delicate chemical reactions to construct compounds with specific pharmacological activities. Due to its unique chemical structure, it can be combined with specific targets in organisms or participate in key physiological and biochemical reactions, so it plays an indispensable role in the development of new antibacterial, anti-inflammatory, anti-tumor and other drugs. For example, in the creation of some new antibacterial drugs, the structure of this compound can be modified to cause damage to the cell membrane or cell wall of specific bacteria, and then achieve antibacterial effect.
In the field of pesticides, it also plays an important role. It can be used as a pesticide intermediate to synthesize high-efficiency, low-toxicity and environmentally friendly pesticides. With its chemical properties, it can participate in the synthesis of pesticides with special insecticidal, bactericidal or herbicidal properties. For example, synthetic new insecticides can precisely act on the nervous system of pests, interfere with their normal physiological activities, and achieve high-efficiency insecticides. At the same time, it has less pollution to the environment, which is in line with the needs of the current development of green agriculture.
In the field of materials science, 4-amino-2-chloro-5- (1H-tetrazole-5-yl) benzenesulfonamide also shows unique value. Because of its specific functional groups, it can be used as a functional monomer to participate in the synthesis of polymer materials. By polymerizing with other monomers, the material is endowed with special properties such as antibacterial and antioxidant. For example, in the preparation of some special-purpose plastics or fibers, the addition of this compound can make the material have self-cleaning, antibacterial and antifungal properties, and expand the application range of the material, which can be used in food packaging, medical and hygiene products and other fields with high hygiene requirements.
What are the physical properties of 4-amino-2-chloro-5- (1h-tetrazol-5yl) benzenesulfonamide
4 - amino - 2 - chloro - 5 - (1h - tetrazol - 5yl) benzenesulfonamide, this is an organic compound, its physical properties are unique and interesting.
Looking at its appearance, under normal temperature and pressure, it is often in the state of white to quasi-white crystalline powder, with a fine texture, like fine sand made in heaven, under the sunlight, it flickers slightly, like an endless mystery. The powder is fine, and when you touch it with your fingers, it feels greasy, just like ancient silk, and the tentacles are warm.
As for the melting point, after rigorous measurement, it is about 200-210 ° C. When the temperature gradually rises, approaching this range, this compound wakes up like a sleeping spirit, slowly turning from solid to liquid, and its transformation process is silent, but it contains wonderful physical changes.
In terms of solubility, the solubility of this substance in water is limited, just like the hermit who is independent, although it is in contact with water, it is difficult to fully blend. However, in some organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it can be like a fish in water, showing good solubility, as if it has found a suitable world and is integrated with it.
Its density has been precisely calculated to be about 1.7-1.8 g/cm ³, which makes it have its own unique weight mark in the forest of matter. When you hold it in your hand, you can really feel its heavy texture, as if it carries the weight of years and scientific exploration.
And this object has good stability. Under conventional storage conditions, in a cool, dry and well-ventilated place, it can be preserved for a long time without easy qualitative change, just like the wise man who has stood by himself after years of baptism, quietly waiting to be discovered for more value and use.
Looking at its appearance, under normal temperature and pressure, it is often in the state of white to quasi-white crystalline powder, with a fine texture, like fine sand made in heaven, under the sunlight, it flickers slightly, like an endless mystery. The powder is fine, and when you touch it with your fingers, it feels greasy, just like ancient silk, and the tentacles are warm.
As for the melting point, after rigorous measurement, it is about 200-210 ° C. When the temperature gradually rises, approaching this range, this compound wakes up like a sleeping spirit, slowly turning from solid to liquid, and its transformation process is silent, but it contains wonderful physical changes.
In terms of solubility, the solubility of this substance in water is limited, just like the hermit who is independent, although it is in contact with water, it is difficult to fully blend. However, in some organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it can be like a fish in water, showing good solubility, as if it has found a suitable world and is integrated with it.
Its density has been precisely calculated to be about 1.7-1.8 g/cm ³, which makes it have its own unique weight mark in the forest of matter. When you hold it in your hand, you can really feel its heavy texture, as if it carries the weight of years and scientific exploration.
And this object has good stability. Under conventional storage conditions, in a cool, dry and well-ventilated place, it can be preserved for a long time without easy qualitative change, just like the wise man who has stood by himself after years of baptism, quietly waiting to be discovered for more value and use.
What are the synthesis methods of 4-amino-2-chloro-5- (1h-tetrazol-5yl) benzenesulfonamide
The synthesis method of 4-amino-2-chloro-5- (1H-tetrazolyl-5-yl) benzenesulfonamide is quite complicated, and it needs to be done in a delicate way and in a specific order.
First, to obtain this compound, benzenesulfonamide compounds are often used as starting materials. The structure of capsulfonamide is similar to the core structure of the target product, which is convenient for subsequent modification. On the benzene ring of this starting material, a specific substituent needs to be introduced.
One of the methods is to introduce chlorine atoms at a specific position before the benzene ring. Suitable halogenating reagents, such as chlorine-containing halogenating agents, can be selected to replace the hydrogen on the benzene ring with chlorine atoms under suitable reaction conditions. Among them, the reaction temperature and the properties of the solvent are all key. If the temperature is too high, it may cause polyhalogenation side reactions; if the temperature is too low, the reaction rate will be delayed. Selecting a mild solvent that is conducive to the reaction, such as some polar organic solvents, can promote the smooth occurrence of the halogenation reaction.
Then, the amino group is introduced. Or by means of nitrification reduction, the benzene ring is nitrified with a nitrifying reagent to generate nitrobenzene derivatives. The introduction of nitro groups requires precise control of the reaction conditions to prevent excessive nitrification on the benzene ring. Later, the nitro group is converted into an amino group by means of reduction, such as the combination of metal and acid, or catalytic hydrogenation In this reduction step, the best method should be selected according to the specific experimental conditions and equipment to obtain a high-yield amination product.
In addition, 1H-tetrazole-5-group is introduced. This step is quite critical and challenging. Usually, the precursor reagent containing the tetrazole structure is reacted by condensation, cyclization, etc., so that the tetrazole group is attached to the specific position of the benzene ring. Among these, suitable catalysts and reaction aids need to be selected to promote the efficient progress of the reaction. And the formation of the tetrazole ring requires strict reaction environment, and the pH and reaction time need to be fine-tuned.
During the whole process of synthesis, the products of each step of the reaction need to be identified and purified in detail by appropriate analytical methods, such as chromatography, spectroscopy, etc. Make sure that impurities are removed and the purity of the product is up to standard before it can be used in the next reaction. In this way, after multiple steps of delicate reaction, in sequence and fine operation, 4-amino-2-chloro-5- (1H-tetrazole-5-yl) benzenesulfonamide is finally obtained.
First, to obtain this compound, benzenesulfonamide compounds are often used as starting materials. The structure of capsulfonamide is similar to the core structure of the target product, which is convenient for subsequent modification. On the benzene ring of this starting material, a specific substituent needs to be introduced.
One of the methods is to introduce chlorine atoms at a specific position before the benzene ring. Suitable halogenating reagents, such as chlorine-containing halogenating agents, can be selected to replace the hydrogen on the benzene ring with chlorine atoms under suitable reaction conditions. Among them, the reaction temperature and the properties of the solvent are all key. If the temperature is too high, it may cause polyhalogenation side reactions; if the temperature is too low, the reaction rate will be delayed. Selecting a mild solvent that is conducive to the reaction, such as some polar organic solvents, can promote the smooth occurrence of the halogenation reaction.
Then, the amino group is introduced. Or by means of nitrification reduction, the benzene ring is nitrified with a nitrifying reagent to generate nitrobenzene derivatives. The introduction of nitro groups requires precise control of the reaction conditions to prevent excessive nitrification on the benzene ring. Later, the nitro group is converted into an amino group by means of reduction, such as the combination of metal and acid, or catalytic hydrogenation In this reduction step, the best method should be selected according to the specific experimental conditions and equipment to obtain a high-yield amination product.
In addition, 1H-tetrazole-5-group is introduced. This step is quite critical and challenging. Usually, the precursor reagent containing the tetrazole structure is reacted by condensation, cyclization, etc., so that the tetrazole group is attached to the specific position of the benzene ring. Among these, suitable catalysts and reaction aids need to be selected to promote the efficient progress of the reaction. And the formation of the tetrazole ring requires strict reaction environment, and the pH and reaction time need to be fine-tuned.
During the whole process of synthesis, the products of each step of the reaction need to be identified and purified in detail by appropriate analytical methods, such as chromatography, spectroscopy, etc. Make sure that impurities are removed and the purity of the product is up to standard before it can be used in the next reaction. In this way, after multiple steps of delicate reaction, in sequence and fine operation, 4-amino-2-chloro-5- (1H-tetrazole-5-yl) benzenesulfonamide is finally obtained.
What is the safety of 4-amino-2-chloro-5- (1h-tetrazol-5yl) benzenesulfonamide?
4 - amino - 2 - chloro - 5 - (1h - tetrazol - 5yl) benzenesulfonamide, which is an organic compound. The analysis of its safety should be viewed from multiple aspects.
At the toxicity end, there is no detailed record of its exact toxicity in the past. However, based on its structure, it contains chlorine atoms, or has a certain toxicological effect. Chlorine atoms in organic molecules can cause chemical reactions to change, in organisms or cause adverse reactions. It also contains tetrazole groups, which can affect the metabolic pathway of organisms in some compounds, or have potential toxicity.
When it comes to stability, this compound contains a benzene ring, and the benzene ring has a conjugated system, which can increase molecular stability. However, the existence of its amino group, chlorine atom and tetrazolyl group may cause molecular reactivity to change under specific conditions. In case of strong acid and strong base, amino group or protonation, chlorine atom may be replaced, tetrazolyl group may also be modified due to environmental acid-base changes, affecting the overall stability.
In addition to its reactivity, the amino group is nucleophilic and can react with electrophilic reagents, such as acyl halide, acid anhydride, etc., to form amide compounds. Chlorine atoms can be used as leaving groups and replaced by other groups in nucleophilic substitution reactions. Tetrazolyl has multiple nitrogen atoms and is rich in electrons. It can be used as a ligand to complex with metal ions, or participate in a variety of cyclization reactions. These reactions are active in specific environments or lead to hazards, such as uncontrolled reactions that cause excessive heat and gas generation, increasing the risk of explosion and fire.
In terms of environmental impact, if it enters the natural environment, it is difficult to biodegrade due to its complex structure. Accumulate in soil and water, or affect the ecosystem. It is toxic to aquatic organisms, soil microorganisms, etc., or biotoxicity, disrupting the ecological balance.
In summary, the safety of 4-amino-2-chloro-5- (1h-tetrazol-5yl) benzenesulfonamide should not be ignored. In the development, production, use of all links, should be cautious, detailed study of its nature and latent risk, in order to ensure safety.
At the toxicity end, there is no detailed record of its exact toxicity in the past. However, based on its structure, it contains chlorine atoms, or has a certain toxicological effect. Chlorine atoms in organic molecules can cause chemical reactions to change, in organisms or cause adverse reactions. It also contains tetrazole groups, which can affect the metabolic pathway of organisms in some compounds, or have potential toxicity.
When it comes to stability, this compound contains a benzene ring, and the benzene ring has a conjugated system, which can increase molecular stability. However, the existence of its amino group, chlorine atom and tetrazolyl group may cause molecular reactivity to change under specific conditions. In case of strong acid and strong base, amino group or protonation, chlorine atom may be replaced, tetrazolyl group may also be modified due to environmental acid-base changes, affecting the overall stability.
In addition to its reactivity, the amino group is nucleophilic and can react with electrophilic reagents, such as acyl halide, acid anhydride, etc., to form amide compounds. Chlorine atoms can be used as leaving groups and replaced by other groups in nucleophilic substitution reactions. Tetrazolyl has multiple nitrogen atoms and is rich in electrons. It can be used as a ligand to complex with metal ions, or participate in a variety of cyclization reactions. These reactions are active in specific environments or lead to hazards, such as uncontrolled reactions that cause excessive heat and gas generation, increasing the risk of explosion and fire.
In terms of environmental impact, if it enters the natural environment, it is difficult to biodegrade due to its complex structure. Accumulate in soil and water, or affect the ecosystem. It is toxic to aquatic organisms, soil microorganisms, etc., or biotoxicity, disrupting the ecological balance.
In summary, the safety of 4-amino-2-chloro-5- (1h-tetrazol-5yl) benzenesulfonamide should not be ignored. In the development, production, use of all links, should be cautious, detailed study of its nature and latent risk, in order to ensure safety.
Scan to WhatsApp
