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4-Amino-2-Chloro-5-(2H-Tetrazol-5-Yl)Benzenesulfonamide
Linshang Chemical
|
HS Code |
636406 |
| Chemical Formula | C7H6ClN5O2S |
| Molecular Weight | 261.67 g/mol |
| Appearance | Solid (usually powder) |
| Melting Point | Data may vary, needs specific experimental determination |
| Solubility In Water | Low solubility, may be sparingly soluble |
| Solubility In Organic Solvents | Solubility varies depending on solvent, e.g., more soluble in polar organic solvents like DMSO |
| Pka Value | Specific pKa values related to functional groups (amine, sulfonamide) would need experimental determination |
| Density | Data may vary, needs experimental measurement |
| Stability | Stable under normal conditions, but may decompose under extreme heat, light or in the presence of certain reactive substances |
As an accredited 4-Amino-2-Chloro-5-(2H-Tetrazol-5-Yl)Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - amino - 2 - chloro - 5 - (2H - tetrazol - 5 - yl)benzenesulfonamide in sealed plastic bags. |
| Storage | Store 4 - amino - 2 - chloro - 5 - (2H - tetrazol - 5 - yl)benzenesulfonamide in a cool, dry place away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent moisture absorption and contact with air, which could potentially lead to decomposition or degradation. Store separately from incompatible substances to avoid chemical reactions. |
| Shipping | 4 - amino - 2 - chloro - 5 - (2H - tetrazol - 5 - yl)benzenesulfonamide is shipped in accordance with strict chemical regulations. It's packaged securely in appropriate containers to prevent leakage during transit. |
Competitive 4-Amino-2-Chloro-5-(2H-Tetrazol-5-Yl)Benzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
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What is the chemical structure of 4-amino-2-chloro-5- (2h-tetrazol-5-yl) benzenesulfonamide?
This is a description of an organic compound named 4-amino-2-chloro-5- (2H-tetrazole-5-yl) benzenesulfonamide. To clarify its chemical structure, it is necessary to first analyze its name. This name is derived from the system nomenclature, which can show the composition and connection of each part of the molecule.
"4-Amino", the 4th position of the epiphenyl ring has an amino group (-NH2O); "2-chlorine" means that the 2nd position of the benzene ring is connected with a chlorine atom (-Cl); "5- (2H-tetrazole-5-yl) ", which means that the 5th position of the benzene ring is connected with 2H-tetrazole-5-yl, and the tetrazole ring contains four nitrogen atoms and one carbon atom to form a five-membered heterocycle. 2H means that the hydrogen atom is connected to the No. 2 nitrogen atom. 5-yl means that this ring is connected to the benzene ring at the 5th position; "benzene sulfonamide" means that the benzene ring is connected to the sulfonamide group (
Its chemical structure is mostly a benzene ring as the core, with a chlorine atom at position 2, an amino group at position 4, and a 2H-tetrazole-5-group at position 5, and the benzene ring is also connected with a sulfonamide group. In this way, the parts are connected in the order indicated by the name, resulting in the chemical structure of 4-amino-2-chloro-5- (2H-tetrazole-5-yl) benzenesulfonamide.
"4-Amino", the 4th position of the epiphenyl ring has an amino group (-NH2O); "2-chlorine" means that the 2nd position of the benzene ring is connected with a chlorine atom (-Cl); "5- (2H-tetrazole-5-yl) ", which means that the 5th position of the benzene ring is connected with 2H-tetrazole-5-yl, and the tetrazole ring contains four nitrogen atoms and one carbon atom to form a five-membered heterocycle. 2H means that the hydrogen atom is connected to the No. 2 nitrogen atom. 5-yl means that this ring is connected to the benzene ring at the 5th position; "benzene sulfonamide" means that the benzene ring is connected to the sulfonamide group (
Its chemical structure is mostly a benzene ring as the core, with a chlorine atom at position 2, an amino group at position 4, and a 2H-tetrazole-5-group at position 5, and the benzene ring is also connected with a sulfonamide group. In this way, the parts are connected in the order indicated by the name, resulting in the chemical structure of 4-amino-2-chloro-5- (2H-tetrazole-5-yl) benzenesulfonamide.
What are the main uses of 4-amino-2-chloro-5- (2h-tetrazol-5-yl) benzenesulfonamide
4 - amino - 2 - chloro - 5 - (2H - tetrazol - 5 - yl) benzenesulfonamide, Chinese name or 4 - amino - 2 - chloro - 5 - (2H - tetrazol - 5 - yl) benzenesulfonamide. This substance has a wide range of uses and is a key intermediate in the field of pharmaceutical research and development. When many new antibacterial and anti-inflammatory drugs are created, they are often used as starting materials and chemically modified to derive compounds with different structures and unique activities to achieve specific therapeutic effects.
In the field of pesticides, it may be involved in the creation of new pesticides. Through the study of its structure modification and activity, pesticide products with high insecticidal and bactericidal properties can be developed, and such pesticides may have low toxicity and environmentally friendly characteristics, which is in line with the current development needs of green agriculture.
In the field of materials science, this compound may participate in the preparation of functional materials due to its special structure and properties. For example, in the synthesis of some intelligent materials with recognition and adsorption functions for specific substances, it can act as a key structural unit and give materials specific functions.
At the level of scientific research, as an important intermediate in organic synthesis, it has made great contributions to the development of organic synthetic chemistry. Through the study of its reactivity and structural properties, researchers have developed new methods and new ideas for organic synthesis, and promoted the progress of organic chemistry.
In the field of pesticides, it may be involved in the creation of new pesticides. Through the study of its structure modification and activity, pesticide products with high insecticidal and bactericidal properties can be developed, and such pesticides may have low toxicity and environmentally friendly characteristics, which is in line with the current development needs of green agriculture.
In the field of materials science, this compound may participate in the preparation of functional materials due to its special structure and properties. For example, in the synthesis of some intelligent materials with recognition and adsorption functions for specific substances, it can act as a key structural unit and give materials specific functions.
At the level of scientific research, as an important intermediate in organic synthesis, it has made great contributions to the development of organic synthetic chemistry. Through the study of its reactivity and structural properties, researchers have developed new methods and new ideas for organic synthesis, and promoted the progress of organic chemistry.
What are the physical properties of 4-amino-2-chloro-5- (2h-tetrazol-5-yl) benzenesulfonamide
4 - amino - 2 - chloro - 5 - (2h - tetrazol - 5 - yl) benzenesulfonamide, which is an organic compound. Its physical properties are as follows:
In appearance, it is often in the state of white to off-white crystalline powder, delicate and pure, like snow falling at the beginning of winter, pure and free of impurities. Looking at it, I feel that its texture is uniform, delicate and subtle, and occasionally shimmering under light, just like snow reflecting sunlight, adding a little agility to its purity. In terms of solubility, in organic solvents such as dimethyl sulfoxide (DMSO), the compound melts like ice in water, quietly disappears, and shows good solubility. It can be integrated with DMSO, regardless of each other. In common organic solvents such as methanol and ethanol, although its solubility is slightly inferior to DMSO, it can also be partially dissolved, just like a drizzle moistening the soil and slowly penetrating into it. However, in water, its solubility is poor, just like oil dripping into water, it is difficult to blend, and it is mostly suspended in tiny particles, left to stand for a while, and then slowly settle.
Melting point is also an important physical property. After rigorous determination, its melting point is about a specific temperature range. Under this temperature, the compound is like a sleeping crystal, with a stable structure and unchanged appearance. However, when the temperature gradually rises to the melting point range, it begins to melt gradually like ice in the warm sun, gradually converting from a solid state to a liquid state, and the shape changes, just like the melting of ice and snow, opening a different state.
In terms of stability, in a normal temperature and pressure and dry environment, its properties are stable, just like ancient objects that have been precipitated over time. It is not easy to react with surrounding substances and can be preserved for a long time without deterioration. However, if placed in extreme environments such as high temperature, high humidity or strong acid and alkali, its stability will be like thin ice on fire, instantly disintegrating, and the structure is easily damaged, which will then trigger chemical reactions and transform into other substances. This compound has unique physical properties and is of great significance for applications in many fields.
In appearance, it is often in the state of white to off-white crystalline powder, delicate and pure, like snow falling at the beginning of winter, pure and free of impurities. Looking at it, I feel that its texture is uniform, delicate and subtle, and occasionally shimmering under light, just like snow reflecting sunlight, adding a little agility to its purity. In terms of solubility, in organic solvents such as dimethyl sulfoxide (DMSO), the compound melts like ice in water, quietly disappears, and shows good solubility. It can be integrated with DMSO, regardless of each other. In common organic solvents such as methanol and ethanol, although its solubility is slightly inferior to DMSO, it can also be partially dissolved, just like a drizzle moistening the soil and slowly penetrating into it. However, in water, its solubility is poor, just like oil dripping into water, it is difficult to blend, and it is mostly suspended in tiny particles, left to stand for a while, and then slowly settle.
Melting point is also an important physical property. After rigorous determination, its melting point is about a specific temperature range. Under this temperature, the compound is like a sleeping crystal, with a stable structure and unchanged appearance. However, when the temperature gradually rises to the melting point range, it begins to melt gradually like ice in the warm sun, gradually converting from a solid state to a liquid state, and the shape changes, just like the melting of ice and snow, opening a different state.
In terms of stability, in a normal temperature and pressure and dry environment, its properties are stable, just like ancient objects that have been precipitated over time. It is not easy to react with surrounding substances and can be preserved for a long time without deterioration. However, if placed in extreme environments such as high temperature, high humidity or strong acid and alkali, its stability will be like thin ice on fire, instantly disintegrating, and the structure is easily damaged, which will then trigger chemical reactions and transform into other substances. This compound has unique physical properties and is of great significance for applications in many fields.
What is the synthesis method of 4-amino-2-chloro-5- (2h-tetrazol-5-yl) benzenesulfonamide
To prepare 4 - amino - 2 - chloro - 5 - (2h - tetrazol - 5 - yl) benzenesulfonamide, the method is as follows:
The starting material needs to prepare a compound containing a benzene ring, which should have a modifiable group to lay the foundation for the subsequent reaction. Take the benzene derivative containing the sulfonamide group first, which is the key to forming the benzene sulfonamide part of the target. On this compound, when finding a suitable check point, chlorine atoms are introduced. The introduction of chlorine atoms is often carried out by chlorination reagents, such as chlorine-containing halogenating agents, under suitable reaction conditions, or heating, or assisted by catalysts, so that chlorine atoms precisely replace hydrogen atoms at specific positions on the benzene ring to obtain 2-chloro-benzenesulfonamide intermediates.
Then, the 5- (2h-tetrazole-5-yl) group is to be added. Often by the method of nitrogen-containing heterocyclic synthesis, starting with a group containing a cyanide group or convertible to a cyanide group, and reacting with azide in a suitable solvent. Cyanide and azide react to form a tetrazole ring structure. This reaction requires attention to the control of reaction conditions. Temperature and pH will affect the efficiency and selectivity of cyclization. After successfully generating an intermediate containing 5- (2h-tetrazole-5-yl), try to connect it with the previously prepared 2-chloro-benzenesulfonamide intermediate.
The linking step requires the help of a coupling reagent or a specific chemical reaction mechanism to make the two skillfully spliced. In this process, the reaction parameters need to be carefully adjusted to ensure that the reaction proceeds in the direction of generating the target product and avoid the growth of side reactions. After the multi-step reaction, layer by layer modification and careful carving, 4-amino-2-chloro-5- (2h-tetrazol-5-yl) benzenesulfonamide was obtained. After each step of the reaction, the intermediate needs to be properly separated and purified to ensure the purity and efficiency of the subsequent reaction, so as to achieve the purpose of synthesis smoothly.
The starting material needs to prepare a compound containing a benzene ring, which should have a modifiable group to lay the foundation for the subsequent reaction. Take the benzene derivative containing the sulfonamide group first, which is the key to forming the benzene sulfonamide part of the target. On this compound, when finding a suitable check point, chlorine atoms are introduced. The introduction of chlorine atoms is often carried out by chlorination reagents, such as chlorine-containing halogenating agents, under suitable reaction conditions, or heating, or assisted by catalysts, so that chlorine atoms precisely replace hydrogen atoms at specific positions on the benzene ring to obtain 2-chloro-benzenesulfonamide intermediates.
Then, the 5- (2h-tetrazole-5-yl) group is to be added. Often by the method of nitrogen-containing heterocyclic synthesis, starting with a group containing a cyanide group or convertible to a cyanide group, and reacting with azide in a suitable solvent. Cyanide and azide react to form a tetrazole ring structure. This reaction requires attention to the control of reaction conditions. Temperature and pH will affect the efficiency and selectivity of cyclization. After successfully generating an intermediate containing 5- (2h-tetrazole-5-yl), try to connect it with the previously prepared 2-chloro-benzenesulfonamide intermediate.
The linking step requires the help of a coupling reagent or a specific chemical reaction mechanism to make the two skillfully spliced. In this process, the reaction parameters need to be carefully adjusted to ensure that the reaction proceeds in the direction of generating the target product and avoid the growth of side reactions. After the multi-step reaction, layer by layer modification and careful carving, 4-amino-2-chloro-5- (2h-tetrazol-5-yl) benzenesulfonamide was obtained. After each step of the reaction, the intermediate needs to be properly separated and purified to ensure the purity and efficiency of the subsequent reaction, so as to achieve the purpose of synthesis smoothly.
What is the market outlook for 4-amino-2-chloro-5- (2h-tetrazol-5-yl) benzenesulfonamide?
4 - amino - 2 - chloro - 5 - (2H - tetrazol - 5 - yl) benzenesulfonamide, which is the name of a chemical substance, often called tetrazolium sulfonamide. Looking at its market prospects, there are many things to be said.
From the perspective of the pharmaceutical field, such compounds may have unique biological activities, or may become key starting materials for the development of new drugs. Today, the pharmaceutical industry is thirsty for novel and highly effective therapeutic drugs, and researchers are constantly looking for potential chemical entities as a weapon to overcome various diseases. Tetrazole sulfonamide may exhibit various biological activities such as antibacterial, anti-inflammatory and even anti-tumor due to its structure containing special tetrazole and sulfonamide groups. Therefore, in the process of innovative drug research and development, it may be a candidate ingredient that has attracted much attention. It is expected that after in-depth research and optimization, new specific drugs will be born, and then a broad market will be opened up.
In the field of agriculture, this substance also has potential applications. With people's increasing requirements for food safety and the quality of agricultural products, the development of high-efficiency, low-toxicity and environmentally friendly pesticide products has become a general trend. The unique chemical structure of tetrazole sulfonamide may endow it with functions such as insecticidal, bactericidal or plant growth regulation. Over time, with proper development, it may become the core ingredient of new pesticides, contributing to ensuring crop harvest and improving the quality of agricultural products, and the market potential should not be underestimated.
Looking at the use of scientific research, because of its unique structure, it may be an important tool for chemical synthesis and medicinal chemistry research. Researchers can use it to carry out reaction mechanism exploration, structure-activity relationship research, etc., to help in-depth understanding of the nature of chemical processes and biological activities, and lay the foundation for more innovative research. In this way, it can also occupy a place in the scientific research reagent market.
However, its market development is not smooth. Optimization of synthetic processes and cost control of large-scale production are all problems that need to be solved urgently. Only by overcoming various obstacles can we fully unleash its market potential and thrive in various fields.
From the perspective of the pharmaceutical field, such compounds may have unique biological activities, or may become key starting materials for the development of new drugs. Today, the pharmaceutical industry is thirsty for novel and highly effective therapeutic drugs, and researchers are constantly looking for potential chemical entities as a weapon to overcome various diseases. Tetrazole sulfonamide may exhibit various biological activities such as antibacterial, anti-inflammatory and even anti-tumor due to its structure containing special tetrazole and sulfonamide groups. Therefore, in the process of innovative drug research and development, it may be a candidate ingredient that has attracted much attention. It is expected that after in-depth research and optimization, new specific drugs will be born, and then a broad market will be opened up.
In the field of agriculture, this substance also has potential applications. With people's increasing requirements for food safety and the quality of agricultural products, the development of high-efficiency, low-toxicity and environmentally friendly pesticide products has become a general trend. The unique chemical structure of tetrazole sulfonamide may endow it with functions such as insecticidal, bactericidal or plant growth regulation. Over time, with proper development, it may become the core ingredient of new pesticides, contributing to ensuring crop harvest and improving the quality of agricultural products, and the market potential should not be underestimated.
Looking at the use of scientific research, because of its unique structure, it may be an important tool for chemical synthesis and medicinal chemistry research. Researchers can use it to carry out reaction mechanism exploration, structure-activity relationship research, etc., to help in-depth understanding of the nature of chemical processes and biological activities, and lay the foundation for more innovative research. In this way, it can also occupy a place in the scientific research reagent market.
However, its market development is not smooth. Optimization of synthetic processes and cost control of large-scale production are all problems that need to be solved urgently. Only by overcoming various obstacles can we fully unleash its market potential and thrive in various fields.
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