Linshang Chemical
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4-Amino-6-Chloro-1,3-Benzenedisulphonamide
Linshang Chemical
|
HS Code |
548338 |
| Chemical Formula | C6H6ClN3O4S2 |
| Molecular Weight | 285.71 g/mol |
| Appearance | Solid (usually white or off - white powder) |
| Solubility In Water | Low solubility, sparingly soluble |
| Solubility In Organic Solvents | Soluble in some polar organic solvents like DMSO, DMF |
| Pka | The sulphonamide groups have pKa values in the acidic range, around 1 - 2 for the more acidic sulphonamide proton |
| Stability | Stable under normal conditions, but may react with strong oxidizing or reducing agents |
As an accredited 4-Amino-6-Chloro-1,3-Benzenedisulphonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 4 - amino - 6 - chloro - 1,3 - benzenedisulphonamide packaged in a sealed plastic bag. |
| Storage | 4 - amino - 6 - chloro - 1,3 - benzenedisulphonamide should be stored in a cool, dry place. Keep it away from heat sources and direct sunlight as high temperatures can potentially degrade the chemical. Store in a well - ventilated area to prevent the build - up of vapors. It should be in a tightly sealed container to avoid moisture absorption and contamination from other substances. |
| Shipping | 4 - amino - 6 - chloro - 1,3 - benzenedisulphonamide is shipped in well - sealed, corrosion - resistant containers. It adheres to strict chemical shipping regulations, ensuring secure transport to prevent spills and exposure during transit. |
Competitive 4-Amino-6-Chloro-1,3-Benzenedisulphonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Amino-6-Chloro-1,3-Benzenedisulphonamide in China?
As a trusted 4-Amino-6-Chloro-1,3-Benzenedisulphonamide manufacturer, we deliver:
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As a leading 4-Amino-6-Chloro-1,3-Benzenedisulphonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
4-Amino-6-chloro-1, what are the chemical properties of 3-benzenedisulphonamide
4 - amino - 6 - chloro - 1,3 - benzenedisulphonamide is an organic compound. Its chemical properties are quite unique, so let me tell you one by one.
This compound contains amino groups (-NH ²), chlorine atoms (-Cl) and sulfonamido groups (-SO2O). The amino group has a certain alkalinity, because it has lone pairs of electrons on the nitrogen atom, it can be combined with protons and is prone to protonation reactions in acidic environments. Although the chlorine atom is relatively stable, it can participate in the reaction due to changes in the conditions of nucleophilic substitution reactions. It can be attacked by nucleophilic reagents, and the chlorine atoms leave to form new compounds.
The sulfonamide group gives the substance a certain degree of polarity and stability. In the sulfonamide structure, the sulfur atom is connected to two oxygen atoms and forms a bond with the nitrogen atom. This structure allows the formation of hydrogen bonds between molecules, which affects their physical and chemical properties. For example, the presence of hydrogen bonds can increase the boiling point and solubility of compounds.
In chemical reactions, the reactivity of 4-amino-6-chloro-1,3-benzenedisulphonamide depends on the interaction of different groups. The basicity of the amino group allows it to participate in the acylation reaction and react with the acylation reagent to form amide derivatives. At the same time, the presence of chlorine atoms provides the possibility for nucleophilic substitution reactions. If suitable nucleophilic reagents are available, the substitution of chlorine atoms can be realized and the variety of chemical derivation can be enriched.
Furthermore, the stability of the compound is also affected by each group. The conjugate structure of the benzene ring imparts certain stability to the molecule, and the interaction of electronic and spatial effects between different substituents determines its chemical behavior in different environments. For example, the electron carrier effect between amino and sulfonamide groups will affect the electron cloud density distribution on the benzene ring, thereby affecting the activity and positional selectivity of electrophilic substitution reactions.
This compound contains amino groups (-NH ²), chlorine atoms (-Cl) and sulfonamido groups (-SO2O). The amino group has a certain alkalinity, because it has lone pairs of electrons on the nitrogen atom, it can be combined with protons and is prone to protonation reactions in acidic environments. Although the chlorine atom is relatively stable, it can participate in the reaction due to changes in the conditions of nucleophilic substitution reactions. It can be attacked by nucleophilic reagents, and the chlorine atoms leave to form new compounds.
The sulfonamide group gives the substance a certain degree of polarity and stability. In the sulfonamide structure, the sulfur atom is connected to two oxygen atoms and forms a bond with the nitrogen atom. This structure allows the formation of hydrogen bonds between molecules, which affects their physical and chemical properties. For example, the presence of hydrogen bonds can increase the boiling point and solubility of compounds.
In chemical reactions, the reactivity of 4-amino-6-chloro-1,3-benzenedisulphonamide depends on the interaction of different groups. The basicity of the amino group allows it to participate in the acylation reaction and react with the acylation reagent to form amide derivatives. At the same time, the presence of chlorine atoms provides the possibility for nucleophilic substitution reactions. If suitable nucleophilic reagents are available, the substitution of chlorine atoms can be realized and the variety of chemical derivation can be enriched.
Furthermore, the stability of the compound is also affected by each group. The conjugate structure of the benzene ring imparts certain stability to the molecule, and the interaction of electronic and spatial effects between different substituents determines its chemical behavior in different environments. For example, the electron carrier effect between amino and sulfonamide groups will affect the electron cloud density distribution on the benzene ring, thereby affecting the activity and positional selectivity of electrophilic substitution reactions.
What are the main uses of 4-amino-6-chloro-1, 3-benzenedisulphonamide
4-Amino-6-chloro-1,3-benzenedisulphonamide, that is, 4-amino-6-chloro-1,3-benzenesulfonamide, is widely used. In the field of medicine, it is often the key raw material for the creation of diuretics. Diuretics can promote the excretion of excess water and salt from the human body, and can treat diseases such as edema and hypertension. By affecting the process of water and electrolytes processed by the kidneys, it can increase the production and excretion of urine, reduce the body's edema, and assist in the regulation of blood pressure.
In the field of agriculture, 4-amino-6-chloro-1,3-benzenediesulfonamide may be involved in the research and development of pesticides. Some pesticides are composed of special chemical substances, which may be key components in them, helping to develop pesticide products with antibacterial, insecticidal and other properties. By inhibiting or killing pests, ensure the healthy growth of crops and improve crop yield and quality.
In the chemical industry, as an important organic synthesis intermediate, it can participate in the synthesis of a variety of complex organic compounds. With its unique chemical structure and reactivity, it can undergo various chemical reactions with other compounds, resulting in many chemical products with specific properties and uses, such as special dyes, functional polymer materials, etc., to meet the special needs of different industrial fields.
4-Amino-6-chloro-1,3-benzenedisulfonamide has important applications in many fields such as medicine, agriculture and chemical industry, and plays an indispensable role in promoting the development of various industries.
In the field of agriculture, 4-amino-6-chloro-1,3-benzenediesulfonamide may be involved in the research and development of pesticides. Some pesticides are composed of special chemical substances, which may be key components in them, helping to develop pesticide products with antibacterial, insecticidal and other properties. By inhibiting or killing pests, ensure the healthy growth of crops and improve crop yield and quality.
In the chemical industry, as an important organic synthesis intermediate, it can participate in the synthesis of a variety of complex organic compounds. With its unique chemical structure and reactivity, it can undergo various chemical reactions with other compounds, resulting in many chemical products with specific properties and uses, such as special dyes, functional polymer materials, etc., to meet the special needs of different industrial fields.
4-Amino-6-chloro-1,3-benzenedisulfonamide has important applications in many fields such as medicine, agriculture and chemical industry, and plays an indispensable role in promoting the development of various industries.
4-Amino-6-chloro-1, what is the production method of 3-benzenedisulphonamide
The preparation method of 4-amino-6-chloro-1,3-benzenedisulphonamide (4-amino-6-chloro-1,3-benzene disulfonamide) is commonly used in the following numbers.
The starting material is often selected from a suitable benzene-based compound, using benzene as the base, and gradually constructing the target molecular structure through specific chemical transformation. Generally, the benzene ring is chlorinated first, so that chlorine atoms are introduced at specific positions on the benzene ring. Usually, under appropriate reaction conditions, chlorine gas can be used as the chlorine source, and when the catalyst exists, chlorine atoms can be introduced precisely at specific positions in the benzene ring, such as position 6.
Then, the benzene ring is sulfonated, aiming to introduce the sulfonyl group at the 1,3 position. The sulfonation reaction commonly uses concentrated sulfuric acid, fuming sulfuric acid, etc. as sulfonation reagents. Under the control of appropriate temperature and reaction time, the purpose of sulfonation at the 1,3 position is achieved, and the corresponding benzene disulfonic acid derivatives are generated.
Furthermore, the sulfonic acid group needs to be converted into a sulfonamide group. It is often reacted with ammonia or amine compounds, and through a series of nucleophilic substitution processes, the sulfonic acid group is converted into a sulfonamide group.
As for the introduction of amino groups, there can be many ways. For example, if there are suitable substituents on the starting material benzene ring, the amino group can be introduced at the 4 position through nucleophilic substitution If there is a nitro group on the benzene ring, the nitro group can be reduced to an amino group by a reducing agent such as iron powder, hydrogen (under the catalysis of suitable catalysts such as palladium carbon), etc., to obtain 4-amino-6-chloro-1,3-benzenedisulphonamide. Each step requires fine regulation of reaction conditions, such as temperature, reactant ratio, reaction time, etc., to ensure the high efficiency of the reaction and the purity of the product.
The starting material is often selected from a suitable benzene-based compound, using benzene as the base, and gradually constructing the target molecular structure through specific chemical transformation. Generally, the benzene ring is chlorinated first, so that chlorine atoms are introduced at specific positions on the benzene ring. Usually, under appropriate reaction conditions, chlorine gas can be used as the chlorine source, and when the catalyst exists, chlorine atoms can be introduced precisely at specific positions in the benzene ring, such as position 6.
Then, the benzene ring is sulfonated, aiming to introduce the sulfonyl group at the 1,3 position. The sulfonation reaction commonly uses concentrated sulfuric acid, fuming sulfuric acid, etc. as sulfonation reagents. Under the control of appropriate temperature and reaction time, the purpose of sulfonation at the 1,3 position is achieved, and the corresponding benzene disulfonic acid derivatives are generated.
Furthermore, the sulfonic acid group needs to be converted into a sulfonamide group. It is often reacted with ammonia or amine compounds, and through a series of nucleophilic substitution processes, the sulfonic acid group is converted into a sulfonamide group.
As for the introduction of amino groups, there can be many ways. For example, if there are suitable substituents on the starting material benzene ring, the amino group can be introduced at the 4 position through nucleophilic substitution If there is a nitro group on the benzene ring, the nitro group can be reduced to an amino group by a reducing agent such as iron powder, hydrogen (under the catalysis of suitable catalysts such as palladium carbon), etc., to obtain 4-amino-6-chloro-1,3-benzenedisulphonamide. Each step requires fine regulation of reaction conditions, such as temperature, reactant ratio, reaction time, etc., to ensure the high efficiency of the reaction and the purity of the product.
What is the price range of 4-amino-6-chloro-1, 3-benzenedisulphonamide in the market?
I don't know the price range of "4 - amino - 6 - chloro - 1,3 - benzenedisulphonamide" in the market. This is a chemical product, and its price may vary depending on purity, output, supply and demand, origin and seller.
If you want to know its price, you can go to the chemical raw material market to inquire about it, and visit various merchants to compare their quotations. You can also use the chemical product trading website to view its listed price to find out its approximate price range. However, the online price may be untrue and is for reference only. The actual price still needs to be confirmed with the seller in detail.
Or consult the chemical industry, who have been here for a long time and are familiar with the market situation, or can tell the recent price range. However, the price of chemical products changes frequently. To obtain accurate prices, it is necessary to inquire in real time and inquire from multiple parties.
If you want to know its price, you can go to the chemical raw material market to inquire about it, and visit various merchants to compare their quotations. You can also use the chemical product trading website to view its listed price to find out its approximate price range. However, the online price may be untrue and is for reference only. The actual price still needs to be confirmed with the seller in detail.
Or consult the chemical industry, who have been here for a long time and are familiar with the market situation, or can tell the recent price range. However, the price of chemical products changes frequently. To obtain accurate prices, it is necessary to inquire in real time and inquire from multiple parties.
4-Amino-6-chloro-1, 3-benzenedisulphonamide precautions during use
4-Amino-6-chloro-1,3-benzene disulfonamide, this is a very important chemical substance. During use, many precautions must be kept in mind.
Those who bear the brunt, safety protection must not be slack. This substance may be toxic and irritating to a certain extent. When in contact, be sure to wear appropriate protective equipment. Gloves are selected to be chemically resistant to protect your hands; protective glasses can effectively block it from splashing into your eyes and avoid eye damage; wearing protective clothing can prevent it from touching your skin. The operation must be carried out in a well-ventilated environment. If conditions permit, it is more appropriate to operate in a fume hood, so that volatile harmful gases can be discharged in time to ensure the safety of the operator's breathing.
Furthermore, accurate operation is essential. When taking the substance, the measuring tool used must be accurate, and the weighing and measurement should be strictly operated according to the standard process to ensure the accuracy of the amount required for the experiment or production. During the dissolution or reaction process, conditions such as temperature and pH should also be carefully controlled. Different reaction conditions may cause the purity and yield of the product to vary greatly. For example, if the temperature is too high or too low, the reaction rate may be abnormal, and even side reactions may be triggered, which will affect the quality of the final product.
Storage should also not be ignored. It should be stored in a dry, cool and ventilated place, away from fire sources and oxidants. Due to its chemical properties or more active, improper storage environment or deterioration will affect the use effect. Storage containers should also be carefully selected, and corrosion-resistant materials should be used to prevent chemical reactions between containers and substances, resulting in leakage or pollution.
In addition, waste disposal after use should also follow relevant regulations and standards. It must not be discarded at will. It should be treated by suitable methods according to its chemical properties to avoid pollution to the environment. In some cases, pre-treatment such as neutralization and precipitation should be carried out before being handed over to professional waste treatment institutions for disposal.
In conclusion, when using 4-amino-6-chloro-1,3-benzene disulfonamide, many aspects such as safety protection, accurate operation, proper storage and rational disposal of waste need to be treated with caution to ensure the safety and efficiency of the use process.
Those who bear the brunt, safety protection must not be slack. This substance may be toxic and irritating to a certain extent. When in contact, be sure to wear appropriate protective equipment. Gloves are selected to be chemically resistant to protect your hands; protective glasses can effectively block it from splashing into your eyes and avoid eye damage; wearing protective clothing can prevent it from touching your skin. The operation must be carried out in a well-ventilated environment. If conditions permit, it is more appropriate to operate in a fume hood, so that volatile harmful gases can be discharged in time to ensure the safety of the operator's breathing.
Furthermore, accurate operation is essential. When taking the substance, the measuring tool used must be accurate, and the weighing and measurement should be strictly operated according to the standard process to ensure the accuracy of the amount required for the experiment or production. During the dissolution or reaction process, conditions such as temperature and pH should also be carefully controlled. Different reaction conditions may cause the purity and yield of the product to vary greatly. For example, if the temperature is too high or too low, the reaction rate may be abnormal, and even side reactions may be triggered, which will affect the quality of the final product.
Storage should also not be ignored. It should be stored in a dry, cool and ventilated place, away from fire sources and oxidants. Due to its chemical properties or more active, improper storage environment or deterioration will affect the use effect. Storage containers should also be carefully selected, and corrosion-resistant materials should be used to prevent chemical reactions between containers and substances, resulting in leakage or pollution.
In addition, waste disposal after use should also follow relevant regulations and standards. It must not be discarded at will. It should be treated by suitable methods according to its chemical properties to avoid pollution to the environment. In some cases, pre-treatment such as neutralization and precipitation should be carried out before being handed over to professional waste treatment institutions for disposal.
In conclusion, when using 4-amino-6-chloro-1,3-benzene disulfonamide, many aspects such as safety protection, accurate operation, proper storage and rational disposal of waste need to be treated with caution to ensure the safety and efficiency of the use process.
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