4-Amino-6-Chloro-1,3-Benzenedisulphonamide (Dsa)
Linshang Chemical
HS Code |
981669 |
Chemical Formula | C6H6ClN3O4S2 |
Molar Mass | 285.71 g/mol |
Appearance | Solid (usually white or off - white) |
Solubility In Water | Moderately soluble |
Melting Point | Approximately 270 - 275 °C |
Odor | Odorless |
Ph In Solution | Neutral (around 7 when dissolved in pure water) |
Stability | Stable under normal conditions |
Reactivity | Reacts with strong oxidizing agents |
As an accredited 4-Amino-6-Chloro-1,3-Benzenedisulphonamide (Dsa) factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 4 - amino - 6 - chloro - 1,3 - benzenedisulphonamide (DSA) in sealed chemical - grade bags. |
Storage | 4 - amino - 6 - chloro - 1,3 - benzenedisulphonamide (DSA) should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contamination. Avoid storing near heat sources or reactive chemicals. Store in a well - ventilated area, preferably in a dedicated chemical storage cabinet to ensure safety. |
Shipping | 4 - amino - 6 - chloro - 1,3 - benzenedisulphonamide (DSA) is shipped in well - sealed containers, following strict chemical transportation regulations. Containers are designed to prevent leakage, ensuring safe transit to destination. |
Competitive 4-Amino-6-Chloro-1,3-Benzenedisulphonamide (Dsa) prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 4-Amino-6-Chloro-1,3-Benzenedisulphonamide (Dsa) supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the agricultural field, DSA also has important uses. Or it can be used to create new pesticides, with its special chemical properties, to achieve effective control of specific pests or pathogens. Some pesticides are synthesized by DSA, or have better targeting, better crop protection effect, and can reduce the adverse impact on the environment.
Furthermore, in the field of materials science, DSA can be used as a raw material for the synthesis of special materials. Because it contains specific functional groups, through specific reactions, or can construct polymer materials with unique properties, such as materials with special electrical and optical properties, it provides assistance for the development of electronics, optics and other fields.
In short, 4-amino-6-chloro-1,3-benzenediesulfonamide has important uses in medicine, agriculture, materials science and other fields, and is of great significance to promote the development of related industries.
It first appears as a white to light yellow crystalline powder, which makes it easy to identify and distinguish in practical application scenarios. From the perspective of solubility, the substance has good solubility in water and can decompose in the middle of water to produce ions. This property is of great significance for its reaction and application in many aqueous solutions.
In terms of acidity and alkalinity, 4-amino-6-chloro-1,3-benzenediesulfonamide is slightly basic due to the presence of amino groups, which can react with acids to form corresponding salts. In this process, the nitrogen atom of the amino group accepts protons by virtue of its lone pair of electrons, showing the characteristics of bases. At the same time, the sulfonamide group has a certain acidity and can give protons under specific conditions. This acid-base amphoteric makes the substance participate in a variety of acid-base related chemical reactions.
4-Amino-6-chloro-1,3-benzenediesulfonamide has relatively high chemical stability and is not easy to decompose on its own under conventional conditions. However, under extreme conditions such as high temperature, strong acid or strong base, its molecular structure may change. For example, in a strong acid environment, the sulfonamide group may hydrolyze, resulting in the destruction of the molecular structure; under strong base conditions, the amino group may participate in the reaction, affecting the original chemical properties and functions of the substance.
In addition, the presence of chlorine atoms in this substance makes it have certain nucleophilic substitution reactivity. The chlorine atom can be substituted by other nucleophiles as a leaving group, so as to modify and modify the molecular structure, providing the possibility for the synthesis of more derivatives with specific functions.
First, the purity of the raw material is the key. In the synthesis of DSA, if the purity of the raw material does not meet the standard, impurities are mixed into the reaction system, or side reactions occur, not only will the purity of the product be poor, but the yield will also be sharply reduced. Therefore, when purchasing raw materials, it is necessary to carefully select suppliers to carefully verify the purity of raw materials and Quality Standards.
Second, precise control of the reaction conditions is indispensable. Temperature, pH value, reaction time and other factors have a profound impact on the reaction process and product quality. If the temperature is too high, or the reaction is out of control and too many impurities are generated; if the temperature is too low, the reaction rate will be slow and take a long time. Or if the pH value is not good, or the reaction cannot proceed according to the expected path. Therefore, the reaction conditions must be monitored with precision instruments during production, and fine-tuned in real time according to the reaction process.
Furthermore, safety in production should not be taken lightly. Some raw materials used in DSA production may be toxic and corrosive, and the operation is slightly careless, which will endanger the safety of personnel and the environment. Operators should have complete protective equipment and be familiar with the characteristics of various chemical substances and emergency treatment methods. The factory also needs to set up perfect ventilation, fire protection and wastewater treatment systems to ensure the safety of the production environment and avoid environmental pollution.
Repeat, the cleaning and maintenance of the equipment is also important. After the production is completed, clean the equipment in time to prevent material residue and corrosion of the equipment, which will affect the next production. Regular comprehensive inspection and maintenance of the equipment can detect potential problems and repair them in time to ensure the stable operation of the equipment, reduce the number of failures and downtime, and ensure the continuity of production.
At the end, quality inspection runs through all the time. From the raw materials entering the factory to the finished product leaving the factory, all links should be strictly tested. Use high performance liquid chromatography, mass spectrometry and other analytical methods to ensure that the product quality meets the standards and prevent substandard products from entering the market, which will damage the reputation of the enterprise and the interests of customers.
In the pharmaceutical field, DSA is often a key intermediate in drug synthesis. With the vigorous development of the pharmaceutical industry, the demand for various high-efficiency drugs is increasing day by day. As an important raw material, the quality and supply stability of DSA are crucial. In recent years, the upsurge of innovative drug research and development has promoted the demand for DSA from pharmaceutical companies. At the same time, the strict standards and long cycle of drug research and development also affect the marketing activities of DSA. If a breakthrough is made in the research and development of new drugs, and a large number of DSA is required as a raw material, the market demand will usher in significant growth; conversely, if the research and development process is blocked, the growth rate of market demand may slow down.
In the chemical industry, DSA can be used as a synthetic raw material for some special chemicals. The diversified development of the chemical industry has a rich and diverse demand for various fine chemicals. With its unique chemical structure, DSA can give specific properties to chemical products. With the technological innovation of the chemical industry, there may be new progress in the development and application of DSA derivatives, thereby expanding the market space of DSA. However, the competition in the chemical industry is intense, and the emergence of new raw materials and new technologies may pose a challenge to DSA's market share.
Furthermore, the impact of environmental protection policies on the market prospects of DSA should not be underestimated. The production process of DSA may involve some links that have an impact on the environment. If environmental protection regulations are tightened, manufacturers must invest more resources in the construction and upgrading of environmental protection facilities, which will increase production costs, or have an impact on market prices and product competitiveness. Some small-scale production enterprises may withdraw from the market due to the increase in environmental protection costs, which will affect the market supply pattern.
Overall, the market prospects of 4-amino-6-chloro-1,3-benzenedisulfonamide (DSA) are full of opportunities and challenges. The development needs of the pharmaceutical and chemical industries provide them with a broad market space, but factors such as R & D risks, competitive pressures, and environmental protection policies also bring many uncertainties to their market development. Enterprises need to gain insight into market dynamics, improve their technical level, and strengthen environmental protection measures in order to occupy a favorable position in the DSA market.
One is the sulfonation and chlorination method. First, benzene is used as the initial raw material, and through the sulfonation reaction, benzene and concentrated sulfuric acid are co-heated under specific temperature and duration conditions to achieve sulfonation, and benzenesulfonic acid intermediates are obtained. Then this intermediate product is reacted with chlorine gas in the presence of a catalyst to achieve the purpose of chlorination, and then 4-hydroxy-6-chloro-1,3-benzenedisulfonic acid is obtained. The raw materials of this method are common, but the reaction steps are slightly complicated, and the sulfonation and chlorination processes have strict requirements on the control of reaction conditions. Accurate temperature control, speed regulation, etc. are required to ensure the purity and yield of the product.
The second is the hydroxyl substitution method. First prepare chlorobenzene sulfonic acid compounds, which can be obtained by chlorination and sulfonation of benzene. Then use appropriate hydroxylation reagents, such as alkali metal hydroxides, etc., under specific solvents and temperatures, the chlorine atoms are replaced by hydroxyl groups to form the target product 4-hydroxy-6-chloro-1,3-benzenesulfonic acid. The advantage of this method is that the hydroxyl group introduction step is relatively direct, but the requirements for reaction conditions and hydroxylation reagent selection are quite high, otherwise it is easy to produce side reactions and affect the quality of the product
The third is the direct synthesis method. Select specific starting materials, such as aromatic compounds with suitable substituents, and directly synthesize 4-hydroxy-6-chloro-1,3-benzene disulfonic acid through one or a few steps. This approach can theoretically reduce the reaction steps and improve the utilization rate of atoms. However, the selection of raw materials and the control of reaction conditions are extremely strict, and the reaction route and catalyst system need to be precisely designed to promote the reaction to proceed in the expected direction and achieve the purpose of efficient synthesis.

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