4-Amino-6-Chloro-M-Benzenedisulfonamide
Linshang Chemical
HS Code |
739939 |
Chemical Formula | C6H7ClN2O4S2 |
Molecular Weight | 268.71 |
Appearance | Typically a solid (physical form can vary based on purity and preparation) |
Melting Point | Specific value would depend on purity and experimental conditions |
Solubility In Water | Limited solubility, being an organic sulfonamide compound |
Solubility In Organic Solvents | Soluble in some polar organic solvents like dimethyl sulfoxide (DMSO) |
Odor | Likely odorless or with a faint, characteristic organic odor |
Stability | Stable under normal conditions, but may react with strong oxidizing or reducing agents |
As an accredited 4-Amino-6-Chloro-M-Benzenedisulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 kg of 4 - amino - 6 - chloro - m - benzenedisulfonamide packaged in air - tight plastic bags. |
Storage | 4 - amino - 6 - chloro - m - benzenedisulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and direct sunlight. Store in a tightly sealed container to prevent moisture absorption and contact with air, which could potentially lead to degradation. It should also be separated from incompatible substances like strong oxidizers and acids. |
Shipping | 4 - amino - 6 - chloro - m - benzenedisulfonamide is shipped in well - sealed, corrosion - resistant containers. It adheres to strict chemical transportation regulations to ensure safety during transit, with special handling to prevent spills and contamination. |
Competitive 4-Amino-6-Chloro-M-Benzenedisulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 4-Amino-6-Chloro-M-Benzenedisulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
- ** Main structure of benzene ring **: With benzene ring as the core structure, benzene ring is a six-membered ring structure composed of six carbon atoms, with high stability and unique electron cloud distribution. In 4-amino-6-chloro-m-benzenedisulfonamide, benzene ring is the carrier basis for other functional groups.
- ** Substituent Distribution **:
- ** 4-position amino group **: At the position 4 of the benzene ring, there is an amino group (-NH -2). The nitrogen atom in the amino group has a lone pair electron, which shows an electron-giving effect, which can increase the electron cloud density of the benzene ring, which in turn affects the chemical activity and reaction check point of the compound. For example, in an electrophilic substitution reaction, the amino group makes the adjacent and para-position of the benzene ring more vulnerable to electrophilic attack.
- ** 6-position chlorine atom **: There is a chlorine atom (-Cl) attached to the position 6. The chlorine atom has strong electronegativity and has an electron-absorbing induction effect, but its p-orbital electrons form p-π conjugation with the large π bond of the benzene ring, and there is a donor-electron conjugation effect, so the overall electronic effect is weak. However, the presence of chlorine atoms still changes the electron cloud distribution of the benzene ring, affecting the reactivity and selectivity.
- ** meta-sulfonamide group **: The meta-position of the benzene ring (m-position) is connected with two sulfonamide groups (-SO _ 2O _ NH _). The sulfur atom in the sulfonamide group is in a high valence state, which has a strong electron-absorbing induction effect, and the sulfonyl group forms a conjugated The presence of two meta-sulfonamide groups greatly reduces the electron cloud density of the benzene ring, decreases the electrophilic substitution reactivity of the benzene ring, and imparts specific physical and chemical properties to the compound, such as certain water solubility and acidity.
The chemical structure of 4-amino-6-chloro-m-benzenedisulfonamide is composed of a benzene ring and a specific amino group, a chlorine atom and a sulfonamide group. The interaction of each part determines the chemical properties and reactivity of the compound.
In the field of medicine, it is often the key intermediate for the synthesis of many drugs. For example, some antibacterial drugs can obtain new compounds with unique antibacterial activities by modifying their chemical structures to resist infections caused by various bacteria. Due to their structural characteristics, they can interact with specific targets in bacteria, or interfere with the normal metabolic process of bacteria, or destroy the synthesis of bacterial cell walls and cell membranes, so as to achieve antibacterial effect.
In the chemical industry, it also has important uses in dye synthesis. It can be used as a raw material for the synthesis of specific structure and color dyes. Due to the functional groups such as amino and sulfonamide groups, it can participate in a variety of chemical reactions, help build complex dye molecular structures, endow dyes with good color fastness, bright color and other characteristics, and meet the needs of high-quality dyes in textile, printing and dyeing industries.
In addition, in the agricultural field, some compounds developed on the basis of 4-amino-6-chloro-isophenyldisulfonamide can be used as pesticide intermediates. After rational design and synthesis, the prepared pesticides can have functions such as insecticidal, weeding or plant growth regulation. For example, some pesticides with specific mechanisms of action can precisely act on specific physiological links of pests, achieving the purpose of high-efficiency and low-toxicity pest control, while having a relatively small impact on the environment, meeting the needs of the development of modern green agriculture.
Its appearance is mostly white to off-white crystalline powder. Looking at it, the pure one has uniform color and luster, and there is no obvious variegation and foreign matter. The powder is delicate and smooth to the touch, which is due to the molecular arrangement and crystalline morphology.
Melting point is one of the important physical properties. The melting point of this substance is in a specific range, about [X] ° C. At this temperature, the substance gradually melts from the solid state to the liquid state. This transition process requires a certain amount of heat to break the interlattice force.
Solubility is also a key property. In water, its solubility is limited and only slightly soluble. This is because although the molecular structure contains polar groups, which can form a certain interaction with water, the overall structure is still hydrophobic, making it difficult to dissolve in polar water. In some organic solvents, such as ethanol, acetone, etc., the dissolution status is slightly better. According to the principle of similar phase dissolution, the polarity and molecular structure of organic solvents are more suitable for 4-amino-6-chloro-m-benzenedisulfonamide, and the intermolecular force is enhanced. Therefore, the dissolution effect is better than that of water.
Its density also has a certain value, about [X] g/cm ³. This value reflects the mass of the substance per unit volume, which can help to consider its floating and mixing characteristics in different media.
In addition, the stability of this substance is of great concern. Under normal temperature and pressure, dark and dry environments, it is relatively stable and the molecular structure is not easy to change. However, if exposed to high temperatures, humidity, or strong light, or in contact with specific chemical substances, the molecular structure may change, causing its physical properties to change as well.
First, it can be started from isophenylenediamine. First, isophenylenediamine is sulfonated with an appropriate sulfonating agent, such as concentrated sulfuric acid, at a specific temperature and reaction time. When sulfonating, it is necessary to pay attention to the precise control of the reaction conditions. Due to different conditions, the check point and degree of sulfonation can be different. After this step, isophenylenediamine disulfonic acid derivatives can be obtained. Subsequently, chlorination reaction is carried out to introduce chlorine atoms. The chlorination reagent can choose suitable chlorine-containing compounds, and the reaction environment needs to be controlled to introduce chlorine atoms accurately into the target position. Finally, after a suitable reaction, one of the sulfonic acid groups is converted into a sulfonamide group to obtain 4-amino-6-chloro-m-benzenedisulfonamide. The reaction conditions of each step of this path are extremely critical, and it is difficult to achieve the expected product with a slight difference.
Second, it is also possible to use m-dichlorobenzene as the starting material. First, the sulfonation reaction of m-dichlorobenzene is carried out to introduce the sulfonic acid group on the benzene ring. Afterwards, through the amination reaction, one of the chlorine atoms is replaced with an amino group to form a 4-amino-6-chloro-isophthalenesulfonic acid-related intermediate. Finally, the sulfonic acid group is converted into a sulfonamide group to obtain the target product. In this route, the selectivity and efficiency of the amination reaction need to be carefully considered, and the reaction conditions need to be carefully regulated in order to obtain a high-purity product.
Third, other suitable benzene derivatives can be selected as the starting materials, and the target molecular structure can be gradually constructed through a series of reactions such as substitution, oxidation, and reduction. However, no matter what path, it is necessary to comprehensively weigh the characteristics of the reactants, the advantages and disadvantages of the reaction conditions, and the purity and yield of the products, and choose the optimal method to effectively synthesize 4-amino-6-chloro-m-benzenedisulfonamide.
First safety protection. This substance may be toxic and irritating, and appropriate protective equipment must be worn when exposed. Wear protective gloves to prevent direct contact with the skin, causing skin allergies or damage; wear safety goggles to protect the eyes from splashing damage; if used in a poorly ventilated place, wear a gas mask to prevent inhalation of its dust or volatile gases, which can damage the respiratory system.
Next time, store properly. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its nature or instability, high temperature, humid environment or deterioration may affect the use effect and even pose a safety hazard. And it needs to be stored separately from oxidants, acids, alkalis, etc., to avoid chemical reactions caused by mixed storage.
Furthermore, the use process must strictly follow the operating procedures. Weigh the required amount accurately, do not increase or decrease at will. When operating, the action should be steady and slow to prevent it from spilling. If it is accidentally spilled, clean it immediately to prevent pollution of the environment or contact with others. When preparing the solution, operate according to the specified ratio and sequence, pay attention to the dissolution temperature and stirring speed, and ensure that it dissolves fully and uniformly.
In addition, the waste after use should not be discarded at will. Dispose of it properly in accordance with relevant regulations and environmental protection requirements. It can be collected and handed over to a professional treatment agency to ensure its safe disposal without polluting the environment.
In short, the use of 4-amino-6-chloro-isophenyldisulfonamide requires safety. All links need to be handled with caution and in accordance with regulations to ensure personnel safety and use results.

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