4-Amino-6-Chlorobenzene-1,3-Disulfonamide
Linshang Chemical
HS Code |
362844 |
Chemical Formula | C6H6ClN3O4S2 |
Molar Mass | 285.71 g/mol |
Appearance | Solid (usually powder) |
Solubility In Water | Poorly soluble |
Solubility In Organic Solvents | Soluble in some polar organic solvents |
Melting Point | Specific value would require experimental data |
Boiling Point | Specific value would require experimental data |
Density | Specific value would require experimental data |
Pka | Specific value would require experimental data |
Odor | Odorless (usually) |
As an accredited 4-Amino-6-Chlorobenzene-1,3-Disulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 4 - amino - 6 - chlorobenzene - 1,3 - disulfonamide in sealed chemical - grade bags. |
Storage | 4 - amino - 6 - chlorobenzene - 1,3 - disulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and contamination. Label the storage container clearly to avoid mix - ups. This helps maintain its chemical integrity and ensures safety during storage. |
Shipping | 4 - amino - 6 - chlorobenzene - 1,3 - disulfonamide is shipped in well - sealed containers, following strict chemical transport regulations. Packaging ensures protection from environmental factors during transit to maintain its integrity. |
Competitive 4-Amino-6-Chlorobenzene-1,3-Disulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 4-Amino-6-Chlorobenzene-1,3-Disulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Looking at its name, it is known that it is based on the benzene ring. The benzene ring, a six-membered carbon ring, has a unique conjugated structure and is the core skeleton of many compounds in organic chemistry. In this compound, there are four substituents above the benzene ring.
One, at position 4, is connected by an amino group (-NH -2). The amino group is composed of a nitrogen atom and two hydrogen atoms bonded, and has the property of electors, which can affect the electron cloud distribution of the benzene ring, thereby affecting the chemical activity of this compound.
Second, at position 6, it is occupied by the chlorine atom (-Cl). The chlorine atom has a certain electronegativity, which can produce induction effects in the molecule, and also affects the benzene ring electron cloud. And because of its large atomic radius, it also has an effect on the spatial structure of the molecule.
Furthermore, positions 1 and 3 are connected with sulfonamide groups (-SO2O) respectively. The sulfonamide group is formed by linking the sulfonyl group (-SO2O) to the amino group. The sulfonyl group has strong electron-withdrawing properties, and the amino group has a tendency to supply electricity. The combination of this structure makes the sulfonamide group exhibit unique chemical properties and plays an important role in many organic reactions.
In summary, the chemical structure of 4-amino-6-chlorobenzene-1,3-disulfonamide is based on a benzene ring, with an amino group at position 4, a chlorine atom at position 6, and a sulfonamide group at positions 1 and 3. Each substituent affects each other, giving this compound specific chemical and physical properties.
In the field of medicine, it is often a key raw material for traditional Chinese medicine, used to prepare a variety of specific drugs. Due to its unique chemical structure, it can interact with specific targets in organisms, exhibiting various pharmacological activities such as antibacterial and anti-inflammatory. For example, some drugs that target specific bacterial infections, this substance plays an indispensable role in it, helping drugs to act precisely on pathogens, inhibit their growth and reproduction, and achieve the purpose of curing diseases.
In the field of agriculture, it also has important functions. It can be used as a component of pesticides and contributes greatly to the control of crop diseases and pests. By interfering with the physiological process of pests or pathogens, it ensures the healthy growth of crops, improves crop yield and quality, and protects the fruits of agricultural harvest.
In industrial production, 4-amino-6-chlorobenzene-1,3-disulfonamide is also useful in dye synthesis. It can give unique color and stability to dyes, making dyes widely used in textile, printing and dyeing and other industries, adding brilliant color to people's lives.
In summary, 4-amino-6-chlorobenzene-1,3-disulfonamide plays a crucial role in many key fields such as medicine, agriculture, and industry, and has a profound impact on human life and production.
Looking at its properties, it may be a white to off-white crystalline powder under normal conditions, which is conducive to preliminary identification and distinction. The texture of the powder is delicate and can be perceived on the touch. This property is also related to subsequent processing and use.
When it comes to melting point, this substance has a specific melting point value. The melting point is the critical temperature at which a substance changes from solid to liquid. The melting point of 4-amino-6-chlorobenzene-1,3-disulfonamide can help identify its purity and is also a key reference for control conditions in chemical production. Those with high purity have a sensitive melting point and approach the theoretical value; if there are many impurities, the melting point shifts and the melting range widens.
Solubility is also an important physical property. It varies in different solvents, and its solubility in water is limited. However, it may have a better solubility in some organic solvents such as ethanol and acetone. This characteristic determines the choice of solvent in the synthesis, separation, purification and other steps, and affects the degree and efficiency of the reaction.
In addition, the density of 4-amino-6-chlorobenzene-1,3-disulfonamide also has a specific value. The density reflects the quality of the substance per unit volume and is of great significance in storage, transportation and preparation. Only by accurately knowing the density can we reasonably plan the packaging and container specifications to ensure the safety and efficiency of operation.
Its odor is weak and almost odorless. This is essential in application scenarios, especially when in contact with the human body or in specific environments. It has no pungent or bad odor, which can increase its convenience and applicability.
To sum up, the physical properties of 4-amino-6-chlorobenzene-1, 3-disulfonamide, such as properties, melting point, solubility, density, odor, etc., are all inherent characteristics, and are indispensable factors in chemical research, industrial production, and practical applications, which have a profound impact on its treatment, transformation, and end use.
First, a suitable starting material needs to be prepared, usually a compound containing a benzene ring as a group, such as a specific substituted benzene. This compound needs to have a group on the benzene ring that can be converted into a target functional group by reaction.
Then, a sulfonyl chloride group can be introduced first. Generally, chlorosulfonic acid or fuming sulfuric acid is co-heated with the starting material. Chlorosulfonic acid has high activity, and when reacting with the benzene ring, a sulfonyl chloride group can be introduced at a specific position. In this reaction, it is necessary to pay attention to the control of the reaction temperature and time. If the temperature is too high, or multiple substitution side reactions occur; if the time is too short, the reaction may be incomplete. After this step, a benzene derivative containing a sulfonyl chloride group can be obtained.
Then the sulfonyl chloride group is converted into a sulfonamide group. The above product can be reacted with ammonia or amine compounds. When ammonia reacts with sulfonyl chloride, the sulfonyl chloride group can be replaced with a sulfonamide group. This step is relatively mild and can be carried out at room temperature or slightly warmed up. However, it is necessary to pay attention to the proportion of the reactants. If there is an excess of ammonia, or other side reactions are initiated; if the amount is insufficient, the transformation is incomplete.
As for the introduction of amino groups, the method of nitro reduction can be used. First, the mixed acid of concentrated nitric acid and concentrated sulfuric acid is reacted with the benzene derivative containing sulfonamide group to introduce nitro groups at specific positions in the benzene ring. This nitrification reaction requires strict temperature control. Due to the violent nitrification reaction, improper temperature is prone to explosion and other dangers. After obtaining the product containing nitro groups, the nitro groups are reduced to amino groups with suitable reducing agents, such as iron powder and hydrochloric acid, lithium aluminum hydride, etc. The reduction method of iron powder and hydrochloric acid is more commonly used, and the reaction is relatively mild and low cost. However, the post-reaction treatment is slightly more complicated, and impurities such as iron salts need to be removed.
After the above steps of reaction, careful operation and proper treatment of the reaction product, 4-amino-6-chlorobenzene-1,3-disulfonamide can be obtained. However, each step of the reaction needs to be strictly operated according to the reaction conditions, and attention should be paid to the separation and purification of the product to improve the purity and yield of the product.
Bear the brunt and be safe. This substance may be toxic and irritating. When exposed, it must be fully armed and well protected. Before starting the operation, read the safety data table carefully to understand the potential hazards. The operation room should be well ventilated to prevent the accumulation of harmful gases. If it comes into contact with the skin or eyes, rinse with plenty of water immediately and seek medical attention immediately.
Furthermore, storage should not be ignored. It should be stored in a cool, dry and ventilated place, away from fire sources and oxidants. Store in categories to avoid mixing with other chemicals to prevent dangerous reactions. Strictly follow the storage conditions, check the packaging regularly, and if there is any damage, dispose of it in time.
During use, precisely control the dose and conditions. According to the experimental or production needs, measure accurately, and must not increase or decrease at will. Follow the established operating procedures and pay attention to the reaction temperature, time and other parameters. If used for synthetic reactions, closely monitor the reaction process to ensure the normal progress of the reaction.
In addition, waste disposal should not be underestimated. It should not be discarded at will, and it needs to be properly disposed of in accordance with relevant regulations and standards. For remaining materials and reaction waste, hand them over to professional institutions for recycling or disposal to protect the environment and avoid pollution.
All these precautions are related to the safety and effectiveness of the use of 4-amino-6-chlorobenzene-1,3-disulfonamide, and must be treated with caution and must not be taken lightly.

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