4-Amino-N-(6-Chloro-5-Methoxy-4-Pyrimidinyl) Benzenesulfonamide(Mcp)
Linshang Chemical
HS Code |
745698 |
Chemical Formula | C11H10ClN5O4S |
Molar Mass | 357.75 g/mol |
Appearance | Typically a solid (color and physical form details may vary based on purity and preparation) |
Solubility | Solubility characteristics can vary; may have limited solubility in water and different solubility in organic solvents |
Melting Point | Specific melting point data would depend on the purity and crystal form, but it has a defined melting point range |
Boiling Point | Boiling point is relevant under appropriate conditions (usually requires high temperatures due to its structure) |
Pka | There are acidic and basic groups in the molecule which can have associated pKa values relevant to its behavior in solution |
Logp | LogP value indicates its lipophilicity, which is important for understanding its distribution between lipid and aqueous phases |
Stability | Stability can be affected by factors like temperature, light, and presence of reactive substances |
Reactivity | Can participate in chemical reactions due to the presence of functional groups like sulfonamide, amino, and pyrimidine moieties |
As an accredited 4-Amino-N-(6-Chloro-5-Methoxy-4-Pyrimidinyl) Benzenesulfonamide(Mcp) factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100 - gram bottles containing 4 - amino - N - (6 - chloro - 5 - methoxy - 4 - pyrimidinyl) Benzenesulfonamide (MCP). |
Storage | Store 4 - amino - N - (6 - chloro - 5 - methoxy - 4 - pyrimidinyl) Benzenesulfonamide (MCP) in a cool, dry place. Keep it away from direct sunlight and sources of heat. Ensure the storage area is well - ventilated. Store in a tightly sealed container to prevent moisture absorption and potential degradation, protecting its chemical integrity. |
Shipping | 4 - amino - N - (6 - chloro - 5 - methoxy - 4 - pyrimidinyl) Benzenesulfonamide (MCP) is shipped in well - sealed, corrosion - resistant containers. It adheres to strict chemical shipping regulations to ensure safe transport due to its chemical nature. |
Competitive 4-Amino-N-(6-Chloro-5-Methoxy-4-Pyrimidinyl) Benzenesulfonamide(Mcp) prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 4-Amino-N-(6-Chloro-5-Methoxy-4-Pyrimidinyl) Benzenesulfonamide(Mcp) supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the process of pharmaceutical research and development, MCP is often used as a key intermediate. Due to its unique chemical structure, it can interact with a variety of biological targets. Physicians and pharmacists use MCP to build more therapeutic drug molecules through exquisite design and synthesis. For example, in the creation of antibacterial drugs, MCP can precisely connect to specific metabolic pathways or proteins in bacteria, interfering with the normal physiological functions of bacteria, so as to inhibit or kill bacteria.
In the treatment of diseases, MCP has a wide range of implications. In the treatment of some inflammatory diseases, it may regulate the body's immune response and reduce inflammatory symptoms. By interfering with cell signaling pathways, it prevents the excessive release of inflammatory mediators and calms the body's inflammatory state. In the exploration of some cancer treatments, MCP has also emerged. It may inhibit the proliferation of tumor cells and induce their apoptosis, providing new ideas and means for solving cancer problems.
In addition, in the field of agriculture, MCP may have potential value. It can be developed as a new type of pesticide to target crop pests and diseases. With its unique chemical properties, it can affect the physiological activities of pests, interfere with their nerve conduction, or damage their digestive system, achieving efficient and low-toxicity pest control and helping agricultural production increase.
Looking at its chemical structure, this compound contains structural fragments of benzenesulfonamide and pyrimidine. The part of benzenesulfonamide gives it specific electronic properties and spatial configuration. The conjugate system of the benzene ring makes the molecule stable to a certain extent, and the sulfonamide group (-SO 2O NH 2O) is a functional group with strong polarity, which can participate in a variety of chemical reactions, such as forming complexes with metal ions, or substitution reactions under suitable conditions, and because it can form hydrogen bonds with other molecules, it also has a significant impact on the solubility, melting point, boiling point and other physical properties of the compound.
The pyrimidine ring part, the substituent of 6-chloro and 5-methoxy group, greatly changes the electron cloud distribution. The chlorine atom has an electron-absorbing induction effect, which can reduce the electron cloud density of the pyrimidine ring and enhance the electrophilic substitution reaction activity on the ring; the methoxy group has the effect of electron conjugation, which has a more complex effect on the electron cloud distribution of the ring, which can adjust the reactivity and chemical stability of the molecule to a certain extent. The combined effect of the two determines the unique chemical properties of this compound.
In terms of reactivity, the amino group (-NH2O) is nucleophilic and easily reacts with electrophilic reagents, such as acylation with acyl halides and acid anhydrides, etc., to generate corresponding amide derivatives. The sulfonyl part of benzenesulfonamide, whose sulfur atom can participate in some reactions as a nucleophilic center, such as reacting with electrophilic reagents to form new sulfur-carbon or sulfur-heteroatom bonds.
Furthermore, due to its containing multiple heteroatoms and polar groups, this compound may have certain solubility in water or polar organic solvents, and solubility is closely related to reactivity and biological activity. In the field of medicinal chemistry, its structural characteristics may make it have potential biological activities, such as antibacterial, antiviral, etc., because it can interact with specific targets in organisms, and interfere with the normal function of biological macromolecules by virtue of non-covalent bonds such as hydrogen bonds and van der Waals forces.
The chemical properties of this compound are determined by its unique structure, and the interaction of various functional groups makes it show broad application prospects in the fields of organic synthesis and drug development. However, further research is needed to understand and utilize its properties.
The selection of starting materials is very critical. Or choose compounds containing pyrimidine structure and derivatives containing benzenesulfonamide structure as starting materials. If 6-chloro-5-methoxy-4-halogenated pyrimidine and p-aminobenzenesulfonamide are used as starting materials, the nucleophilic substitution reaction can be used to promote the synthesis process. In this reaction, the amino group of p-aminobenzenesulfonamide is nucleophilic, while the halogen atom of 6-chloro-5-methoxy-4-halopyrimidine is the electrophilic site. In a suitable solvent, such as dimethylformamide (DMF) or acetonitrile, an appropriate amount of base, such as potassium carbonate or triethylamine, can promote the deprotonation of the amino group of p-aminobenzenesulfonamide and enhance its nucleophilicity. When the temperature is raised to a suitable temperature and the reaction takes place for a period of time, the nucleophilic substitution reaction can occur to generate the target product 4-amino-N - (6-chloro-5-methoxy-4-pyrimidinyl) benzenesulfonamide.
After the reaction is completed, the product needs to be separated and purified. The column chromatography method is often used to select the appropriate stationary phase and mobile phase, and the separation is achieved according to the difference in the distribution coefficient between the product and the impurity between the stationary phase and the mobile phase. The recrystallization method can also be used to select a suitable solvent, and the pure target product can be obtained by taking advantage of the different solubility of the product and the impurity in the solvent at different temperatures.
Synthesis of 4-amino-N- (6-chloro-5-methoxy-4-pyrimidinyl) benzenesulfonamide requires precise control of starting materials, reaction conditions, separation and purification to ensure the purity and yield of the product.
Looking at its market prospects, its potential is still obvious. At the end of pharmaceutical research and development, many studies have shown its potential value in the treatment of specific diseases. For example, for certain types of inflammation and related diseases, it may be used as a lead compound. After optimization and transformation, it is expected to become a new drug with high efficiency and low toxicity. Due to the current demand for innovative drugs in the pharmaceutical market, those who can target difficult diseases and have good safety will surely attract attention. If MCP can follow this path, in-depth study of pharmacological mechanisms, and improve pharmacokinetic properties, it will be able to occupy a seat in the market.
In the field of chemical production, MCP, as a key intermediate, can derive a variety of high-value-added products. With the vigorous development of the fine chemical industry, the demand for characteristic intermediates is increasing. Due to its unique structure, MCP can add to the innovation of chemical products. If manufacturers can optimize production processes, improve yield and purity, and reduce costs, they will be able to stand out in the market competition and expand their application scope to more chemical segments.
However, its market also has challenges. Developing new drugs requires huge funds and long cycles, and the success rate is not 100%. In chemical production, the pressure of environmental protection is increasing day by day, and the production process must meet the strict environmental protection standards, otherwise it may be restricted to stop production. But in general, if the challenges can be properly met and the opportunities can be grasped, the market prospect of 4-amino-N - (6-chloro-5-methoxy-4-pyrimidinyl) benzenesulfonamide (MCP) is still promising.
First, safety protection must be comprehensive. This substance may have certain toxicity and irritation. When contacting, it must be fully armed, wearing protective clothing, protective gloves and goggles to prevent direct contact with skin and eyes. In case of inadvertent contact, rinse with plenty of water immediately. In severe cases, seek medical attention in time.
Second, storage conditions are strict. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its chemical properties or instability, improper storage can easily deteriorate or cause dangerous reactions. At the same time, it should be stored separately from oxidants, acids, alkalis and other substances to avoid accidents caused by mixing with each other.
Third, the operation must be precise and standardized. Before use, the relevant equipment and instruments need to be fully inspected and calibrated to ensure that they are in good working condition. During operation, strictly follow the established operating procedures and process flow, and precisely control the reaction conditions, such as temperature, pressure, reaction time, etc. Minor deviations may have a significant impact on the reaction results and even cause safety accidents.
Fourth, waste disposal should not be underestimated. After use, the remaining substance and related waste must not be discarded at will. It needs to be properly disposed of in accordance with relevant environmental regulations and regulations. Generally speaking, it should be collected in categories and handed over to professional environmental protection treatment institutions for harmless disposal to prevent pollution to the environment.
Only when using 4-amino-N - (6-chloro-5-methoxy-4-pyrimidinyl) Benzenesulfonamide (MCP), the above precautions should be highly regarded and strictly implemented to ensure the safety and efficiency of the use process, while minimizing the potential harm to the environment and human body.

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