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4-Amino-N-(6-Chloropyrazin-2-Yl)Benzenesulfonamide

Linshang Chemical

Specifications

HS Code

314981

Chemical Formula C11H9ClN4O2S
Molecular Weight 296.73 g/mol
Appearance Solid (predicted)
Solubility Solubility in water is low, but may dissolve in some organic solvents (predicted)
Logp Predicted to have some lipophilicity
Stability Stable under normal conditions (predicted), but may react with strong oxidizing or reducing agents

As an accredited 4-Amino-N-(6-Chloropyrazin-2-Yl)Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - amino - N - (6 - chloropyrazin - 2 - yl)benzenesulfonamide in sealed plastic bags.
Storage 4 - amino - N - (6 - chloropyrazin - 2 - yl)benzenesulfonamide should be stored in a cool, dry place, away from direct sunlight. Keep it in a well - sealed container to prevent moisture absorption and exposure to air, which could potentially lead to degradation. Store it separately from incompatible substances, such as strong oxidizing agents or acids, to avoid chemical reactions.
Shipping 4 - amino - N - (6 - chloropyrazin - 2 - yl)benzenesulfonamide is shipped in accordance with strict chemical transport regulations. Packaged securely to prevent leakage, it's transported by approved carriers, ensuring safety during transit.
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4-Amino-N-(6-Chloropyrazin-2-Yl)Benzenesulfonamide 4-Amino-N-(6-Chloropyrazin-2-Yl)Benzenesulfonamide
General Information
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Frequently Asked Questions

As a leading 4-Amino-N-(6-Chloropyrazin-2-Yl)Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of 4-amino-n- (6-chloropyrazin-2-yl) benzenesulfonamide?
This is about the chemical structure of "4 - amino - n- (6 - chloropyrazin - 2 - yl) benzenesulfonamide". This compound is analyzed according to chemical nomenclature. "4 - amino", indicating that its benzene ring is connected to an amino group at position 4; "n- (6 - chloropyrazin - 2 - yl) ", showing that the nitrogen atom of benzenesulfonamide group is related to 6 - chloropyrazine - 2 - group; "benzenesulfonamide", its core is determined to be benzenesulfonamide structure.
Described in the style of the ancient Chinese saying of "Tiangong Kaiwu", it is said: "This compound is originally in the shape of benzenesulfonamide. Above the benzene ring, there are amino groups attached at the four corners. There are nitrogen atoms, connected to 6-chloropyrazin-2-yl. Chlorine is located at the sixth of the pyrazine ring, and the second of the pyrazines is connected to nitrogen, forming this unique shape. In this way, it is the chemical structure of 4-amino-n- (6-chloropyrazin-2-yl) benzenesulfonamide." The characteristics of this structure are actually determined by the position and connection mode of each group, and the elements cooperate with each other to form this specific chemical morphology.
What are the main uses of 4-amino-n- (6-chloropyrazin-2-yl) benzenesulfonamide?
4-Amino-N- (6-chloropyrazin-2-yl) benzenesulfonamide, commonly known as 6-chloropyrazin-2-yl-4-aminobenzenesulfonamide in Chinese, is an organic compound. Its main uses involve the field of medical chemistry, as detailed below:
First, in the process of drug development, this compound can be used as a key intermediate. Taking the creation of innovative drugs as an example, pharmaceutical chemists hope to obtain new compounds with specific biological activities and pharmacological properties by ingeniously modifying and modifying their structures. For example, by connecting it to a larger molecular structure by specific chemical means, it may be possible to develop drugs with high affinity and selectivity for specific disease targets, laying the foundation for solving difficult diseases.
Second, in the field of antimicrobial drug research, 6-chloropyrazine-2-yl-4-aminobenzenesulfonamide has shown potential value. Studies have found that some compounds derived from this basis have the effect of inhibiting growth or killing specific bacteria. This provides new ideas for the development of new antimicrobial drugs, which is expected to alleviate the current problem of bacterial resistance and add new means to clinical anti-infective treatment.
Third, in the field of cancer treatment drug exploration, this compound has also attracted attention. Scientists speculate that by precisely regulating its structure, drugs that can interfere with specific signaling pathways or metabolic processes of cancer cells may be designed, thus achieving the purpose of inhibiting cancer cell proliferation and inducing cancer cell apoptosis, providing innovative strategies and drug candidates for cancer treatment.
What is the synthesis of 4-amino-n- (6-chloropyrazin-2-yl) benzenesulfonamide?
4 - amino - N - (6 - chloropyrazin - 2 - yl) benzenesulfonamide is also an organic compound. The synthesis method often requires a multi-step reaction, which is based on the principles of organic chemistry.
The first step is to always take appropriate starting materials, such as compounds containing benzenesulfonyl groups and compounds containing pyrazinyl groups. When preparing benzenesulfonyl-containing raw materials, or starting from benzene, the sulfonyl group can be introduced through a sulfonation reaction, and then treated with appropriate amination reagents to obtain benzenesulfonyl compounds containing amino groups.
As for the raw materials containing pyrazinyl groups, or suitable nitrogen-containing heterocyclic compounds can be halogenated to introduce chlorine atoms at specific positions in the pyrazine ring, such as the 6-position.
Then, these two types of raw materials undergo a condensation reaction, so that the benzenesulfonyl group is connected to the pyrazine group to form the basic structure of the target molecule. This condensation reaction may require specific catalysts and reaction conditions, such as a suitable base to promote the reaction, and control the reaction temperature and time to ensure that the reaction proceeds in the direction of generating the target product.
During the reaction process, attention should be paid to the selectivity and yield of each step of the reaction. Since organic reactions are often accompanied by side reactions, it is necessary to fine-tune the reaction conditions, such as temperature, reactant ratio, solvent, etc., to improve the purity and yield of the target product. After the reaction is completed, it is often necessary to separate and purify steps, such as column chromatography, recrystallization, etc., to obtain pure 4-amino-N- (6-chloropyrazin-2-yl) benzenesulfonamide products. In this way, the synthesis of this compound can be obtained.
What are the physical properties of 4-amino-n- (6-chloropyrazin-2-yl) benzenesulfonamide?
4 - amino - N - (6 - chloropyrazin - 2 - yl) benzenesulfonamide is an organic compound. Looking at its physical properties, under normal temperature and pressure, this substance is mostly in a solid state, or a crystalline solid. The lid has a certain lattice structure due to the interaction force between molecules.
When it comes to color, it is usually white or off-white, which is due to the absorption and reflection characteristics of the molecular structure of the compound for visible light. When it is in the solid state, the texture is more delicate, and the particle uniformity may vary depending on the preparation method.
With regard to the melting point, it has been determined by many experiments that it is about a certain temperature range. This is because the intermolecular forces require a specific energy to overcome, and then the substance changes from a solid state to a liquid state.
In terms of solubility, the solubility in water is quite limited. This is because although there are polar groups such as amino groups in the molecule of the compound, the hydrophobic part of the overall molecular structure accounts for a large proportion, and it is difficult to form a strong enough interaction with water molecules to achieve good solubility. However, in some organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., it has good solubility, because these organic solvents can form interactions such as van der Waals forces and hydrogen bonds with the compound molecules, which can help them disperse and dissolve.
Its density is also one of the important physical properties, and a specific value can be obtained by accurate measurement. This value reflects the mass of the substance per unit volume, and has a key guiding significance for its measurement and operation in practical applications.
What are the chemical properties of 4-amino-n- (6-chloropyrazin-2-yl) benzenesulfonamide?
4 - amino - N - (6 - chloropyrazin - 2 - yl) benzenesulfonamide is an organic compound with unique chemical properties.
It contains an amino group (-NH2O), and the amino group is nucleophilic and easily reacts with electrophilic reagents. If it can react with acylating reagents to form an amide bond, this reaction is often used in organic synthesis to construct complex structures. And because it is attached to the benzene ring, the activity is changed due to the electronic effect of the benzene ring.
Sulfonamide group (-SO 2O NH-) is also a key structure. The group is acidic to a certain extent, and the hydrogen on the nitrogen atom can be partially ionized, making it acidic under appropriate conditions. And the sulfonamide group has a regulatory effect on the electron cloud distribution of the benzene ring, affecting the activity and check point selectivity of the substitution reaction on the benzene ring.
6-chloropyrazine-2-yl part, the chlorine atom has an electron-absorbing induction effect, which reduces the electron cloud density of the pyrazine ring and the activity of the electrophilic substitution reaction, but enhances its tendency to react with nucleophiles. The pyrazine ring is a nitrogen-containing heterocycle, which has a certain alkalinity and can form salts with acids, which may be used in pharmaceutical preparations or separation and purification.
The compound as a whole presents unique physicochemical properties due to the interaction of different groups. Its solubility may vary depending on the hydrophilicity and hydrophobicity of each group, and the molecular polarity affects its dissolution in different solvents. Melting point and boiling point are also affected by intermolecular forces, such as hydrogen bonds, van der Waals forces, etc.
This compound may have potential uses in organic synthesis and medicinal chemistry. Its unique chemical properties provide a basis for the design and synthesis of new compounds and the exploration of biological activities.