Linshang Chemical
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4-Bromo-1,2-Dichlorobenzene
Linshang Chemical
|
HS Code |
583826 |
| Chemical Formula | C6H3BrCl2 |
| Molar Mass | 225.898 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Odor | Aromatic odor |
| Density | 1.828 g/cm³ |
| Boiling Point | 240 - 242 °C |
| Melting Point | -11 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | 104.4 °C |
As an accredited 4-Bromo-1,2-Dichlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - bromo - 1,2 - dichlorobenzene packaged in a sealed, corrosion - resistant bottle. |
| Storage | 4 - bromo - 1,2 - dichlorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames as it is potentially flammable. Keep it in a tightly sealed container to prevent leakage and exposure to air or moisture. Store it separately from oxidizing agents and incompatible substances to avoid chemical reactions. |
| Shipping | 4 - bromo - 1,2 - dichlorobenzene is shipped in tightly sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring proper labeling and secure handling during transportation to prevent leakage and ensure safety. |
Competitive 4-Bromo-1,2-Dichlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Bromo-1,2-Dichlorobenzene in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Bromo-1,2-Dichlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-bromo-1,2-dichlorobenzene?
4-Bromo-1,2-dichlorobenzene is also an organic compound. It has a wide range of main uses and plays an important role in many fields of chemical industry.
In the process of pharmaceutical synthesis, 4-bromo-1,2-dichlorobenzene is often the key intermediate. Based on this, chemists can prepare a variety of drugs with specific curative effects through complex chemical reactions. Due to its unique structure, it can introduce specific functional groups into drug molecules, which help to adjust key properties such as drug activity, solubility and bioavailability. For example, in the synthesis of certain antimicrobial drugs, 4-bromo-1,2-dichlorobenzene provides a structural basis that allows the resulting drug to more easily bind to targets in bacteria, thereby effectively inhibiting bacterial growth and reproduction.
In the field of materials science, this compound also plays an important role. It can participate in the preparation of high-performance polymers. By polymerizing with other monomers, 4-bromo-1,2-dichlorobenzene can give polymers unique properties. Such as improving the heat resistance, chemical resistance and mechanical strength of polymers. In electronic materials, polymers containing 4-bromo-1,2-dichlorobenzene structure may exhibit good electrical properties and are suitable for the manufacture of printed circuit boards, electronic packaging materials, etc.
In the field of pesticides, 4-bromo-1,2-dichlorobenzene is also an important raw material for the synthesis of high-efficiency pesticides. After chemical modification, pesticide products with high selectivity and strong toxicity to specific pests can be prepared. Such pesticides play an indispensable role in ensuring crop yield and quality, and can accurately kill pests while reducing adverse effects on the environment and non-target organisms.
In addition, 4-bromo-1,2-dichlorobenzene is often used as a starting material or key intermediate in the synthesis of fine chemical products such as dyes and fragrances, giving unique structures and properties to a wide variety of fine chemicals.
In the process of pharmaceutical synthesis, 4-bromo-1,2-dichlorobenzene is often the key intermediate. Based on this, chemists can prepare a variety of drugs with specific curative effects through complex chemical reactions. Due to its unique structure, it can introduce specific functional groups into drug molecules, which help to adjust key properties such as drug activity, solubility and bioavailability. For example, in the synthesis of certain antimicrobial drugs, 4-bromo-1,2-dichlorobenzene provides a structural basis that allows the resulting drug to more easily bind to targets in bacteria, thereby effectively inhibiting bacterial growth and reproduction.
In the field of materials science, this compound also plays an important role. It can participate in the preparation of high-performance polymers. By polymerizing with other monomers, 4-bromo-1,2-dichlorobenzene can give polymers unique properties. Such as improving the heat resistance, chemical resistance and mechanical strength of polymers. In electronic materials, polymers containing 4-bromo-1,2-dichlorobenzene structure may exhibit good electrical properties and are suitable for the manufacture of printed circuit boards, electronic packaging materials, etc.
In the field of pesticides, 4-bromo-1,2-dichlorobenzene is also an important raw material for the synthesis of high-efficiency pesticides. After chemical modification, pesticide products with high selectivity and strong toxicity to specific pests can be prepared. Such pesticides play an indispensable role in ensuring crop yield and quality, and can accurately kill pests while reducing adverse effects on the environment and non-target organisms.
In addition, 4-bromo-1,2-dichlorobenzene is often used as a starting material or key intermediate in the synthesis of fine chemical products such as dyes and fragrances, giving unique structures and properties to a wide variety of fine chemicals.
What are the physical properties of 4-bromo-1,2-dichlorobenzene?
4-Bromo-1,2-dichlorobenzene is one of the organic compounds. Its physical properties are quite impressive.
Under normal temperature and pressure, it often takes the form of a colorless to light yellow liquid. When it is pure, it is clear and transparent, with shimmering light, like the crystal of morning dew.
As for its smell, it has a special aromatic smell. However, this fragrance is not pleasant and fragrant, and the smell is pungent. If you stay in it for a long time, it will be uncomfortable, because it has a certain irritation.
When it comes to the boiling point, it is about 245 ° C. At this temperature, the liquid gradually turns into a gas and rises into the air. The number of boiling points is an important physical property and is indispensable in separation, purification and other processes.
And the melting point is about -21 ° C. When the temperature drops to this temperature, the originally flowing liquid gradually solidifies and turns into a solid state, such as the ice on the lake surface, the shape changes, and the physical properties also change.
Its density is greater than that of water, about 1.87 g/³ cm. Placing it in one place with water shows that it sinks to the bottom of the water, like a stone falling into the abyss, which is due to the difference in density.
In terms of solubility, it is extremely difficult to dissolve in water, just like the incompatibility of oil and water. However, in organic solvents such as ethanol, ether, benzene, etc., they are quite compatible, like a duck to water, and they are completely soluble. This property is very useful in organic synthesis and related chemical operations.
The physical properties of 4-bromo-1,2-dichlorobenzene have their own uses. They are all key factors in many fields such as chemical industry and scientific research. They are related to the success or failure of the process and the quality of the product.
Under normal temperature and pressure, it often takes the form of a colorless to light yellow liquid. When it is pure, it is clear and transparent, with shimmering light, like the crystal of morning dew.
As for its smell, it has a special aromatic smell. However, this fragrance is not pleasant and fragrant, and the smell is pungent. If you stay in it for a long time, it will be uncomfortable, because it has a certain irritation.
When it comes to the boiling point, it is about 245 ° C. At this temperature, the liquid gradually turns into a gas and rises into the air. The number of boiling points is an important physical property and is indispensable in separation, purification and other processes.
And the melting point is about -21 ° C. When the temperature drops to this temperature, the originally flowing liquid gradually solidifies and turns into a solid state, such as the ice on the lake surface, the shape changes, and the physical properties also change.
Its density is greater than that of water, about 1.87 g/³ cm. Placing it in one place with water shows that it sinks to the bottom of the water, like a stone falling into the abyss, which is due to the difference in density.
In terms of solubility, it is extremely difficult to dissolve in water, just like the incompatibility of oil and water. However, in organic solvents such as ethanol, ether, benzene, etc., they are quite compatible, like a duck to water, and they are completely soluble. This property is very useful in organic synthesis and related chemical operations.
The physical properties of 4-bromo-1,2-dichlorobenzene have their own uses. They are all key factors in many fields such as chemical industry and scientific research. They are related to the success or failure of the process and the quality of the product.
What are the chemical properties of 4-bromo-1,2-dichlorobenzene?
4-Bromo-1,2-dichlorobenzene belongs to the genus of organohalogenated aromatics. In its molecular structure, bromine atoms and dichlorine atoms above the benzene ring occupy specific positions, and this structure greatly affects its chemical properties.
As far as the reactivity is concerned, the electron cloud density of the benzene ring is reduced due to the electron-absorbing induction effect of the halogen atom, and the electrophilic substitution activity is lower than that of benzene. However, under suitable conditions, electrophilic substitution can still occur, and the halogen atom is an ortho-para-site group, so the electrophilic reagents tend to be ortho-or para-site attack of the halogen atom.
The substitution reaction of the halogen atom, the bromine and chlorine atoms in this compound can be replaced by nucleoph When encountering strong nucleophilic reagents, such as sodium alcohol, ammonia, etc., halogen atoms can undergo nucleophilic substitution with them, and the activity of bromine atoms is slightly higher than that of chlorine atoms. Because the carbon-bromine bond energy is lower than that of carbon-chlorine bonds, bromine atoms are more likely to leave.
And because it contains halogen atoms, it can participate in metal-catalyzed coupling reactions, such as the construction of carbon-carbon bonds with organometallic reagents under the action of palladium, nickel and other metal catalysts, which is widely used in the field of organic synthesis. It can be used to synthesize complex organic molecules.
In addition, under reduction conditions, halogen atoms can be reduced and removed. For example, metal zinc and acid are used as reducing agents, halogen atoms can be gradually removed to restore the benzene ring to a relatively simple state. However, this reduction process requires precise control of the reaction conditions to prevent excessive reduction or other side reactions.
The chemical properties of 4-bromo-1,2-dichlorobenzene are determined by its structure, and it has important applications in many fields such as organic synthesis, pharmaceutical chemistry, and materials science. With in-depth understanding of its reactivity, chemists can more subtly manipulate the reaction to create the desired organic compounds.
As far as the reactivity is concerned, the electron cloud density of the benzene ring is reduced due to the electron-absorbing induction effect of the halogen atom, and the electrophilic substitution activity is lower than that of benzene. However, under suitable conditions, electrophilic substitution can still occur, and the halogen atom is an ortho-para-site group, so the electrophilic reagents tend to be ortho-or para-site attack of the halogen atom.
The substitution reaction of the halogen atom, the bromine and chlorine atoms in this compound can be replaced by nucleoph When encountering strong nucleophilic reagents, such as sodium alcohol, ammonia, etc., halogen atoms can undergo nucleophilic substitution with them, and the activity of bromine atoms is slightly higher than that of chlorine atoms. Because the carbon-bromine bond energy is lower than that of carbon-chlorine bonds, bromine atoms are more likely to leave.
And because it contains halogen atoms, it can participate in metal-catalyzed coupling reactions, such as the construction of carbon-carbon bonds with organometallic reagents under the action of palladium, nickel and other metal catalysts, which is widely used in the field of organic synthesis. It can be used to synthesize complex organic molecules.
In addition, under reduction conditions, halogen atoms can be reduced and removed. For example, metal zinc and acid are used as reducing agents, halogen atoms can be gradually removed to restore the benzene ring to a relatively simple state. However, this reduction process requires precise control of the reaction conditions to prevent excessive reduction or other side reactions.
The chemical properties of 4-bromo-1,2-dichlorobenzene are determined by its structure, and it has important applications in many fields such as organic synthesis, pharmaceutical chemistry, and materials science. With in-depth understanding of its reactivity, chemists can more subtly manipulate the reaction to create the desired organic compounds.
What are the synthesis methods of 4-bromo-1,2-dichlorobenzene?
4-Bromo-1,2-dichlorobenzene is also an organic compound. The method of synthesis is quite difficult, but there are various ways to find.
One method is to use o-dichlorobenzene as the starting material, through the reaction of bromination, this compound can be obtained. O-dichlorobenzene and bromine, in the presence of suitable catalysts such as iron powder or iron tribromide, can undergo a substitution reaction. In this reaction, bromine atoms replace hydrogen atoms on the benzene ring, and due to the positioning effect of existing chlorine atoms on the benzene ring, the bromine atoms are mainly replaced in specific positions, thereby generating 4-bromo-1,2-dichlorobenzene. When reacting, it is necessary to pay attention to control the temperature of the reaction, the amount of bromine and the proportion of the catalyst. If the temperature is too high, side reactions such as polybromination may occur; improper bromine dosage will also affect the purity and yield of the product.
Another method is to use 1,2-dichloro-4-nitrobenzene as the starting material. The nitro group is first reduced to an amino group to obtain 1,2-dichloro-4-aminobenzene. This reduction reaction can be carried out with suitable reducing agents, such as iron and hydrochloric acid. Then, the amino group is converted into a diazo salt through diazotization. The diazonium salt reacts with cuprous bromide and hydrobromic acid, and the Sandmeier reaction occurs. The diazonium group is replaced by bromine atoms, and finally 4-bromo-1,2-dichlorobenzene is obtained. There are many steps in this pathway, but the conditions of each step of the reaction must be carefully regulated to ensure the smooth progress of each step of the reaction, so as to obtain a product with higher yield and purity.
In addition, other benzene derivatives with suitable substituents can also be used to synthesize 4-bromo-1,2-dichlorobenzene through multi-step transformation. However, no matter what method is used, it is necessary to have a deep understanding and grasp of the principles of organic synthesis, reaction conditions, separation and purification of products, etc., in order to effectively and efficiently synthesize this compound.
One method is to use o-dichlorobenzene as the starting material, through the reaction of bromination, this compound can be obtained. O-dichlorobenzene and bromine, in the presence of suitable catalysts such as iron powder or iron tribromide, can undergo a substitution reaction. In this reaction, bromine atoms replace hydrogen atoms on the benzene ring, and due to the positioning effect of existing chlorine atoms on the benzene ring, the bromine atoms are mainly replaced in specific positions, thereby generating 4-bromo-1,2-dichlorobenzene. When reacting, it is necessary to pay attention to control the temperature of the reaction, the amount of bromine and the proportion of the catalyst. If the temperature is too high, side reactions such as polybromination may occur; improper bromine dosage will also affect the purity and yield of the product.
Another method is to use 1,2-dichloro-4-nitrobenzene as the starting material. The nitro group is first reduced to an amino group to obtain 1,2-dichloro-4-aminobenzene. This reduction reaction can be carried out with suitable reducing agents, such as iron and hydrochloric acid. Then, the amino group is converted into a diazo salt through diazotization. The diazonium salt reacts with cuprous bromide and hydrobromic acid, and the Sandmeier reaction occurs. The diazonium group is replaced by bromine atoms, and finally 4-bromo-1,2-dichlorobenzene is obtained. There are many steps in this pathway, but the conditions of each step of the reaction must be carefully regulated to ensure the smooth progress of each step of the reaction, so as to obtain a product with higher yield and purity.
In addition, other benzene derivatives with suitable substituents can also be used to synthesize 4-bromo-1,2-dichlorobenzene through multi-step transformation. However, no matter what method is used, it is necessary to have a deep understanding and grasp of the principles of organic synthesis, reaction conditions, separation and purification of products, etc., in order to effectively and efficiently synthesize this compound.
What to pay attention to when storing and transporting 4-bromo-1,2-dichlorobenzene
4-Bromo-1,2-dichlorobenzene is also an organic compound. When storing and transporting, pay attention to many matters.
The first priority is safety. This compound has certain toxicity and irritation, and contact can cause human damage. Therefore, the storage place must be well ventilated and away from fire and heat sources to prevent the risk of fire and explosion. When handling, the operator should wear protective clothing, protective gloves and goggles to avoid contact with the skin and eyes. In case of accidental contact, rinse with plenty of water immediately and seek medical treatment.
Second words storage conditions, it should be stored in a cool, dry place to prevent moisture. Because it is sensitive to humidity, damp or deterioration, it affects its quality and use efficiency. At the same time, it should be stored separately from oxidants, alkalis, etc., and must not be mixed with storage and transportation, because the reaction with it may be dangerous.
Furthermore, when transporting, be sure to ensure that the packaging is complete and the loading is secure. The transportation vehicle should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. During the journey, it is necessary to prevent exposure to the sun, rain and high temperature. Transport in accordance with relevant regulations and standards, and strictly abide by the operating procedures to ensure the safety of the transportation process.
All of these are for the storage and transportation of 4-bromo-1,2-dichlorobenzene. Be careful to avoid hazards and ensure the safety of personnel and the environment.
The first priority is safety. This compound has certain toxicity and irritation, and contact can cause human damage. Therefore, the storage place must be well ventilated and away from fire and heat sources to prevent the risk of fire and explosion. When handling, the operator should wear protective clothing, protective gloves and goggles to avoid contact with the skin and eyes. In case of accidental contact, rinse with plenty of water immediately and seek medical treatment.
Second words storage conditions, it should be stored in a cool, dry place to prevent moisture. Because it is sensitive to humidity, damp or deterioration, it affects its quality and use efficiency. At the same time, it should be stored separately from oxidants, alkalis, etc., and must not be mixed with storage and transportation, because the reaction with it may be dangerous.
Furthermore, when transporting, be sure to ensure that the packaging is complete and the loading is secure. The transportation vehicle should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. During the journey, it is necessary to prevent exposure to the sun, rain and high temperature. Transport in accordance with relevant regulations and standards, and strictly abide by the operating procedures to ensure the safety of the transportation process.
All of these are for the storage and transportation of 4-bromo-1,2-dichlorobenzene. Be careful to avoid hazards and ensure the safety of personnel and the environment.
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